[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dietary-protein\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dietary-protein":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100571566","continuous-vs-bolus-protein-protein-regimen-outcomes-in-critically-ill-children-kids-in-distress-100571566",false,"NCT06721923","Continuous vs Bolus Protein (Protein Regimen Outcomes) in Critically Ill Children (Kids In Distress)","Continuous Versus Bolus Dietary Protein and Nutrition Status in the Pediatric Intensive Care Unit: Pilot Study","PRO-KID","Inclusion Criteria:\n\n* Children admitted to PICU over 1 year of age and younger than 11 years of life\n* Expected to remain in the pediatric intensive care unit for longer than 72 hours\n* Receiving standard pediatric formula via NGT\u002FOGT\u002FGT\n\nExclusion Criteria:\n\n* Neuromuscular condition such as muscular dystrophy\n* Admitted with home prescription for high dose steroids, receives growth hormone or insulin\n* Enteral nutrition is contraindicated or if nutrition requirements are partially\u002Ffully met by parenteral nutrition\n* Formula delivered into the small bowel (duodenum\u002Fjejunum, NJT\u002FGJ)\n* Those who require a highly specialized diet (E.g., large burns or metabolic diseases)\n* Patients with a cow's milk protein allergy cannot safely receive a whey-based protein supplement","ALL","1 Year","11 Years",{"count":21,"type":22},96,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this intervention study is to evaluate the difference in nutrition status markers (weight and muscle mass) when giving dietary protein by continuous or bolus delivery in critically ill children ages 1-11y.\n\nThe main questions it aims to answer are:\n\nPrimary: Bolus protein delivery will lessen the decline in mid-upper arm circumference (MUAC) z-score by 0.5 standard deviation in critically ill children aged 1-11y after 1wk. Ultrasound will correlate to MUAC.\n\nSecondary: Bolus protein delivery will provide more (grams per day) than when provided continuously, therefore it is more likely to meet the minimum estimated needs.\n\nParticipants will have daily nutrition intake data collected, and undergo body composition measures (weight, MUAC and ultrasound of the upper thigh muscle) at day of enrollment, and MUAC\u002FUltrasound on follow up days 3, 5, 7 and 14 after the intervention started.",[28,29,30,31],"Critical Illness","Pediatric Intensive Care","Enteral Nutrition Therapy","Dietary Protein",[33,34,35,36,37,38],"enteral nutrition","pediatric critical care","bolus protein delivery","continuous protein delivery","ultrasound","mid-upper arm circumference","RECRUITING","2026-02-09",{"date":42,"type":43},"2026-02-12","ACTUAL",{"date":45,"type":43},"2024-02-13",{"date":47,"type":22},"2027-12-12",{"name":49,"class":50},"University of British Columbia","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":23,"phases":64,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100556464","dietary-protein-sources-and-glycemic-variability-100556464","NCT06525441","Dietary Protein Sources and Glycemic Variability","The Impact of Dietary Protein Sources on Glycemic Variability in Overweight or Obese Individuals: a Randomized Controlled Trial","ProG","Inclusion Criteria:\n\n1. Men or women aged 20-65 years.\n2. Body Mass Index (BMI) greater than 25kg\u002Fm2.\n3. Capable of using a smartphone application daily for taking photos and recording dietary intake.\n4. Maintained stable body weight over the past three months with a regular routine.\n5. Possess self-care ability for independent living.\n6. Not currently participating in any other clinical research projects.\n7. Signed the informed consent form and willing to adhere to and complete the entire research process.\n\nExclusion Criteria:\n\n1. With diagnosed diabetes.\n2. With severe cardiovascular or cerebrovascular diseases (e.g., angina, myocardial infarction, or stroke) or cancer.\n3. Taking medications affecting weight or energy intake\u002Fenergy expenditure in the last 3 months, including weight loss medications, antipsychotic drugs or other medications as determined by the study physician.\n4. Participating in weight loss treatments.\n5. History of severe gastrointestinal diseases or gastrointestinal surgery within the past 12 months.\n6. Those with allergic reactions to common foods (for example, eggs, nuts, grains) or those who are lactose intolerant.\n7. Women who are pregnant or plan to become pregnant.\n8. Diagnosis of HIV, hepatitis B or C, or active tuberculosis.\n9. Special groups who are specifically unsuitable for a diet consisting of whole plant proteins.\n10. Patients who are unwilling or unable to give informed consent.",true,"20 Years","65 Years",{"count":21,"type":22},[25],"This goal of trial is to evaluate the effects of plant-based vs. animal-based diets on glycemic variability in overweight or obese adults through a 3-week dietary intervention.\n\nThe main question it aims to answer is:\n\nWill a plant-based diet be able to reduce glycemic variability in overweight or obese adults compared with an animal-based diet?\n\nParticipants will strictly follow a designated plant-based or animal-based dietary regimen throughout the duration of the 3-week study. They will wear a Continuous Glucose Monitor (CGM) throughout the study, engage in weekly clinical assessments, and record their daily dietary intake.",[67,68,69,70,31],"Metabolic Disease","Diabetes","Overweight","Obesity","NOT_YET_RECRUITING","2024-07-29",{"date":74,"type":43},"2024-07-31",{"date":76,"type":22},"2024-08-01",{"date":78,"type":22},"2025-02-01",{"name":80,"class":50},"Guangdong Provincial People's Hospital"]