[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dietary-supplementation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dietary-supplementation":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100622465","the-impact-of-12-week-retention-of-nutrients-on-skin-and-the-perception-of-physical-health-status-100622465",false,"NCT07383974","The Impact of 12 Week Retention of Nutrients on Skin and the Perception of Physical Health Status","Inclusion Criteria:\n\n1. Chinese adults of Asian descent aged 18 and above;\n2. Daily fruit and vegetable intake \\\u003C 240g (calculated based on the fruit and vegetable section of the food frequency questionnaire);\n3. S3 measurement index \\\u003C 30000;\n4. Participants must possess basic Chinese reading comprehension and expression skills, and be able to independently complete questionnaire surveys;\n5. Voluntary participation in the test and signing of the informed consent form;\n6. Willingness to comply with all evaluation requirements.\n\nExclusion Criteria:\n\n1. Presence of open facial skin lesions, clearly visible scars, acne marks, etc.;\n2. Skin lesions, scars, or significant pigmentation on the hand measurement area;\n3. Symptoms of skin disease on the face or hand measurement areas;\n4. Having undergone medical aesthetic procedures within the last 6 months;\n5. Participation in other clinical trials involving product use within the last 3 months;\n6. Use of health supplements or nutritional supplements (e.g., vitamins, minerals) within the last 1 month;\n7. Currently planning for pregnancy, pregnant, or lactating;\n8. Presence of any disease under current treatment;\n9. Any other health issues or chronic diseases that affect behavioral or cognitive abilities;\n10. Other iatrogenic reasons identified by experts or professionals that may affect the evaluation results.\n\nThe S3 instrument refers to a Raman spectroscopy-based biophotonic scanner. The threshold for the S3 screening value is based on previously published literature, which indicated that participants with a daily fruit and vegetable intake of less than 240g had an average Raman spectroscopy biophotonic scanner score below 25,000. However, considering practical recruitment challenges, the inclusion criterion was set at \\\u003C 30,000. The S3 device measures the Skin Carotenoid Index, a non-invasive biomarker reflecting skin carotenoid levels.",true,"ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"NA","This is a randomized, double-blind, placebo-controlled clinical trial exploring the effects of a 12-week dietary supplement regimen on skin condition and perceived overall health status.\n\nThe study will involve 120 healthy Chinese adults aged 18 and above with low daily fruit and vegetable intake. Participants will be randomly assigned to one of two groups: one group will take a combination of Nu Skin's Vitamin C \\& Green Tea Capsules and Multivitamin \\& Mineral Capsules, while the other group will take a matching placebo.\n\nThe primary goal is to assess if the supplement combination improves skin health after 12 weeks, measured through specialized facial imaging (assessing spots, redness, evenness) and probe measurements (assessing elasticity, moisture, gloss). Secondary goals include evaluating changes in participants' self-perceived health status (via quality of life, fatigue, and digestive health questionnaires), psychological resilience, memory, and exploring a new method for measuring skin carotenoid levels.\n\nThis study is not intended to verify the approved health functions of the products but to explore the potential combined effects of antioxidant and nutritional supplementation on skin and general well-being.",[26,27,28,29,30],"Healthy Volunteers","Dietary Supplementation","Skin Health","Health Status","Antioxidants","RECRUITING","2026-01-26",{"date":34,"type":35},"2026-02-03","ACTUAL",{"date":37,"type":35},"2025-11-03",{"date":39,"type":20},"2026-02-02",{"name":41,"class":42},"ChinaNorm","INDUSTRY",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":15,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":43},"100535816","resistance-exercise-induced-anabolism-in-youths-and-adults-100535816","NCT06256744","Resistance Exercise-induced Anabolism in Youths and Adults","Inclusion Criteria:\n\n* healthy\n* free of injury that would prevent resistance exercise\n\nExclusion Criteria:\n\n* consumed any medications in the past year which may affect muscle function\n* had an injury in the past 6 months that would limit the movements required for the protocols\n* been told that has diabetes\n* been told that had a heart problem\n* been told that have a breathing problem (e.g., asthma)\n* been told that sometimes experience seizures\n* had joint instability or ongoing join chronic pain\n* been told that had kidney problems\n* had stomach problems such as ulcers\n* experience prolonged bleeding after a cut","7 Years","35 Years",{"count":53,"type":20},60,[23],"Resistance exercise training (RET) in children and adolescents has become a popular area of research, with a growing body of evidence supporting its use. Position and consensus statements about RET for children indicate that it is safe and effective at increasing muscular strength, improving sport performance, and mitigating injury risk. Neural and muscular mechanisms can improve muscle strength following RET. Neural factors include improved recruitment and firing of an individual's motor units, and muscular factors primarily include an increase in the size of the muscle (hypertrophy).\n\nIn children, little is known about how these mechanisms relate to muscle strength. There is very little evidence of morphological changes following RET in children. Therefore, conventional wisdom is that children rely only on neural factors to improve strength following RET. Nevertheless, some studies have suggested RET-induced muscle hypertrophy in children and adolescents, indicating that with certain training protocols, children may achieve muscle growth.\n\nHypertrophy of muscle fibres occurs when the rate of muscle protein synthesis (MPS) is greater than the rate of protein breakdown, and is enhanced with the ingestion of dietary amino acids. Due to ethical concerns with obtaining muscle samples (i.e., from muscle biopsies) in pediatric populations, MPS rates have not been previously assessed following RET in children. Recent advancements in stable-isotope methodology (specifically, leucine) allow for the estimation of MPS in a non-invasive breath test.\n\nThe objective of the proposed research is to examine the effects of an acute bout of RET on leucine retention (a proxy for MPS) in children, adolescents, and adults using a non-invasive breath test.",[27,57],"Exercise",[59,60,61,62],"Children","Muscle","Protein","Resistance training","2024-08-14",{"date":65,"type":35},"2024-08-16",{"date":67,"type":20},"2024-09",{"date":69,"type":20},"2025-09",{"name":71,"class":72},"Brock University","OTHER"]