[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"digestive-system-surgical-procedures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:digestive-system-surgical-procedures":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100634426","comparing-traditional-risk-scores-and-an-ai-based-multimodal-model-for-predicting-cardiovascular-events-after-gastrointestinal-surgery-100634426",false,"NCT07539532","Comparing Traditional Risk Scores and an AI-Based Multimodal Model for Predicting Cardiovascular Events After Gastrointestinal Surgery","Value of Some Risk Scores in Predicting Cardiovascular Events After Gastrointestinal Surgery","GI-MACE-AI","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Undergoing gastrointestinal surgery at Bach Mai Hospital between January 2025 and December 2026.\n* Available preoperative, intraoperative, and postoperative data sufficient for analysis.\n\nExclusion Criteria:\n\n* Death within 24 hours after surgery due to a clearly non-cardiovascular cause.\n* Incomplete data required for analysis.","ALL","16 Years",{"count":20,"type":21},5000,"ESTIMATED","30 Days","OBSERVATIONAL","The goal of this observational study is to develop and evaluate an artificial intelligence (AI)-based multimodal model for predicting major cardiovascular events within 30 days after gastrointestinal surgery in adults at Bach Mai Hospital. The study will also compare the predictive performance of this AI-based model with commonly used traditional risk scores.\n\nThe main questions it aims to answer are:\n\nCan an AI-based multimodal model predict major cardiovascular events within 30 days after gastrointestinal surgery? Does the AI-based model show better predictive performance than the Revised Cardiac Risk Index (RCRI), the American College of Surgeons National Surgical Quality Improvement Program Myocardial Infarction or Cardiac Arrest calculator (ACS NSQIP MICA), and the ACS NSQIP Surgical Risk Calculator (ACS NSQIP SRC)? Researchers will compare the AI-based multimodal model with traditional risk scores using measures of predictive performance, including discrimination, calibration, net reclassification improvement, and integrated discrimination improvement.\n\nParticipants will be adults undergoing gastrointestinal surgery. Researchers will review medical record data from patients treated in 2025 and will also collect the same types of clinical data prospectively in 2026. The clinical outcome being predicted is the occurrence of major cardiovascular events within 30 days after surgery. The study will not change routine clinical care.",[26,27,28],"Postoperative Complications","Cardiovascular Diseases","Digestive System Surgical Procedures",[30,31,32,33],"Major adverse cardiovascular events","Gastrointestinal surgery","Artificial intelligence","Multimodal model","RECRUITING","2026-04-16",{"date":37,"type":38},"2026-04-20","ACTUAL",{"date":40,"type":38},"2026-01-01",{"date":42,"type":21},"2026-07-31",{"name":44,"class":45},"Bach Mai Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100379390","study-to-evaluate-the-efficacy-of-a-polyamine-deficient-diet-for-treating-postoperative-pain-after-abdominal-surgery-100379390","NCT04219956","Study to Evaluate the Efficacy of a Polyamine-deficient Diet for Treating Postoperative Pain After Abdominal Surgery","A Prospective Randomized Multicenter Study to Evaluate the Efficacy of a Polyamine-deficient Diet for the Treatment of Postoperative Pain After Abdominal Surgery.","POLYAMAL","Inclusion Criteria:\n\n* Adult (\\>18 years)\n* Indication for a \" major \" abdominal surgery as second surgical procedure : cure of eventration and restoration of digestive continuity\n* Intended Use of a Patient Controlled Morphine Pump (PCA) postoperatively or taking oral opioids\n* Possible follow-up during 7 months (post-operative consultation at 1 month and 6 months only if postoperative pain or complications)\n* Written informed consent form obtained from the patient\n* Affiliated to the social security\n\nExclusion Criteria:\n\n* Pregnant women\n* Minor, adult under guardianship or benefiting from a legal protection\n* Oncological surgery\n* Surgery not painful (cholecystectomy, hernia, thyroidectomy, bariatric surgery)\n* Drug addicts patients, or under opiate dependency\n* Chronic pain patients (pain over 3 months)\n* Patients in nursing home or convalescence home (diet non possible in institution)\n* Planned hospitalisation before the intervention (during the 7 days before the surgery)\n* Severe undernutrition defined by the HAS criteria (weight loss \\> 10% in 1 month and\u002For \\> 15% in 6 months, albumin at inclusion \\\u003C15g\u002Fl)\n* Patient refusing the possibility to change his eating habits\n* Oral feeding impossible preoperatively\n* Patient not able to express himself on their pain (silent, …)\n* Decompensated psychiatric pathologies (severe depression syndrome,…)\n* Patient unable to understand the protocol and\u002For to give his informed consent","18 Years",{"count":57,"type":21},278,"INTERVENTIONAL",[60],"NA","The aim of this study is to evaluate if a polyamine deficient diet started 7 days prior to a major abdominal surgery (eventration cure and digestive continuity) and followed 7 days post-surgery reduces the area under the curve of the numerical pain rating scale in the 72 hours post-surgery.",[28],[64,65,66,67,68],"Abdominal surgery","Polyamine","Postoperative pain","Morphine","Hypersensitivity","2025-11-13",{"date":71,"type":38},"2025-11-14",{"date":73,"type":38},"2020-02-03",{"date":75,"type":21},"2027-11",{"name":77,"class":45},"Nantes University Hospital",4]