[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"digital-intervention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:digital-intervention":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,85,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100623739","prospective-exploratory-study-on-the-comprehensive-application-effectiveness-of-exercise-prescription-decision-support-tools-in-the-management-of-patients-with-four-highs-hypertension-hyperglycemia-hyperlipidemia-hyperuricemia-100623739",false,"NCT07400549","Prospective Exploratory Study on the Comprehensive Application Effectiveness of Exercise Prescription Decision Support Tools in the Management of Patients With \"Four Highs\" (Hypertension, Hyperglycemia, Hyperlipidemia, Hyperuricemia)","Inclusion Criteria:\n\n1. Aged 18 years or older.\n2. Willing to participate in the study and able to provide written informed consent.\n3. Diagnosed with at least one of the following \"Four Highs\" conditions:\n\n   Hypertension: Diagnosed primary hypertension, defined as seated office SBP ≥ 140 mmHg and\u002For DBP ≥ 90 mmHg on at least three non-consecutive days, or currently taking antihypertensive medication. Blood pressure must be controlled while on four or more antihypertensive agents. Diabetes Mellitus: Diagnosed diabetes, defined as having typical symptoms plus random plasma glucose ≥ 11.1 mmol\u002FL, or fasting plasma glucose ≥ 7.0 mmol\u002FL, or 2-hour plasma glucose during OGTT\n\n   ≥ 11.1 mmol\u002FL, or HbA1c ≥ 6.5%, or currently taking glucose-lowering medication. HbA1c level must be between 6.5% and 13.0%. Hyperlipidemia: Diagnosed hyperlipidemia, defined as total cholesterol (TC) ≥ 6.22 mmol\u002FL, or LDL-C ≥ 4.14 mmol\u002FL, or HDL-C \\\u003C 1.04 mmol\u002F L, or triglycerides (TG) \\> 2.26 mmol\u002FL, or currently taking lipid-lowering medication. Hyperuricemia: Diagnosed hyperuricemia, defined as a fasting serum uric acid level \\> 420 μmol\u002FL (7 mg\u002FdL) in men and postmenopausal women, or \\> 360 μmol\u002FL (6 mg\u002FdL) in premenopausal women, on two non-consecutive days under a normal purine diet, or currently taking urate-lowering medication.\n4. Capable of using a smartphone.\n5. A local permanent resident who receives basic public health service management at the designated community health center\u002Fstation or township hospital.\n6. Has not engaged in regular moderate- to vigorous-intensity physical activity (defined as at least 30 minutes per session, on at least 3 days per week) in the past three months.\n\nExclusion Criteria:\n\nPatients meeting any of the following criteria will be excluded:\n\n1. History or acute episode of cardiovascular or cerebrovascular disease, including: angina pectoris, myocardial infarction, coronary revascularization surgery, stroke (ischemic or hemorrhagic, including transient ischemic attack), symptomatic peripheral arterial disease requiring surgery or diagnosed by vascular imaging, ventricular arrhythmia, uncontrolled atrial fibrillation, congestive heart failure (New York Heart Association Class III or IV), hypertrophic cardiomyopathy, history of aneurysm with diameter ≥ 5.5 cm or prior aneurysm surgery.\n2. Current malignant tumor or history of malignant tumor within the past five years.\n3. Contraindications to exercise, such as bone and joint diseases.\n4. Severe respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), restricted lung volume (due to obesity, pregnancy, or spinal deformity), or cystic fibrosis.\n5. Neuromuscular and degenerative diseases, such as muscular dystrophy, poliomyelitis, and dementia.\n6. Severe mental illness, including schizophrenia, bipolar disorder, eating disorders, or depression (with hospitalization for the condition within the past 6 months).\n7. Movement and other neurological disorders, such as Huntington's disease, torsion dystonia, Parkinson's disease, and certain epileptic disorders.\n8. Severe comorbidities with a life expectancy of less than 24 months.\n9. Plans to relocate from the area within the next three months.\n10. Participation in other physical activity level intervention programs within the six months prior to the screening visit.\n11. Current participation in another randomized clinical trial.\n12. Any other condition that, in the investigator's judgment, may interfere with adherence to the trial protocol.","ALL","18 Years",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study conducted a six-month exploratory clinical trial to evaluate the impact of an exercise prescription mini-program, based on the \"Exercise Guidelines for the 'Four Highs'\", on the physical activity levels and related health indicators of patients with hypertension, hyperglycemia, hyperlipidemia, and hyperuricemia in primary healthcare settings in China.",[25,26,27,28,29],"Hypertension","Hyperglycemia","Hyperlipidemia","Hyperuricemia","Digital Intervention",[31,32,33,34],"Digitally-Enabled Health","Chronic Disease Prevention and Control","Sports prescription","Primary health care (PHC)","RECRUITING","2026-02-09",{"date":38,"type":39},"2026-02-10","ACTUAL",{"date":41,"type":39},"2025-06-01",{"date":43,"type":19},"2026-03-01",{"name":45,"class":46},"China National Center for Cardiovascular Diseases","OTHER_GOV",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":16,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":69,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":47},"100613917","usability-study-of-gestational-and-postpartum-weight-management-program-100613917","NCT07272824","Usability Study of Gestational and Postpartum Weight Management Program","Usability Study of Gestational and 6 Months Postpartum Weight Management Program - Hope D","Hope-D_Use","Inclusion Criteria:\n\n* General pregnant women with prepregnancy BMI at least 30 kg\u002Fm2\n* Competence in using the digital care pathway and electronic maternity card\n\nExclusion Criteria:\n\n\\- Significant difficulty in cooperating (e.g. inadequate Finnish language skills)",true,"FEMALE","50 Years",{"count":60,"type":19},30,"OBSERVATIONAL","The principal aim of this study is to evaluate the usability of the Hope-D gestational and 6 months postpartum weight management program. We will evaluate the usability, functionality, and acceptability of the developed Hope-D weight management program that includes digital pathway for weight management, general or individual weight management plan and individual or group coaching for weight management from pregnancy to 6 months postpartum.",[64,65,66,67,29,68],"Pregnancy","Postpartum","Obese Pregnant Women","Weight Management","Usability",[70,71,72,73,74,75],"Hope-D","digital pathway","Gestational weight management","Postpartum weight management","gestational weight management plan","coaching","2025-12-16",{"date":78,"type":39},"2025-12-23",{"date":80,"type":39},"2025-12-09",{"date":82,"type":19},"2026-01-31",{"name":84,"class":46},"Turku University Hospital",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":56,"sex":15,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":20,"phases":96,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":5},"100603672","a-digital-intervention-to-improve-oral-health-practices-100603672","NCT07139561","A Digital Intervention to Improve Oral Health Practices","Oral Health in Hands: A Digital Intervention to Improve Oral Health Practices in Children","Inclusion Criteria:\n\n* Parents or primary caregivers of children aged 6-10 years.\n* Child must be free from major systemic illnesses or developmental disabilities that could interfere with oral hygiene practices.\n* Parent\u002Fcaregiver owns a smartphone with access to WhatsApp or similar digital platform.\n* Ability to read or understand Urdu or English instructions.\n* Willingness to participate for the full 12-week duration and provide informed consent.\n\nExclusion Criteria:\n\n* Children with serious medical conditions (e.g., immunodeficiency, congenital anomalies) that may affect oral health.\n* Parents or children currently enrolled in another oral health education or digital intervention program.\n* Children who have received professional oral health education or structured interventions within the past 4 months.\n* Parents\u002Fcaregivers unwilling or unable to comply with digital reporting and participation requirements.","6 Years","10 Years",{"count":95,"type":19},800,[22],"This study evaluates a 16-week parent-focused digital intervention to improve oral health practices in children aged 6-10 through daily reminders, quizzes, challenges, gamification, and behavior tracking, supported by an optional moderated WhatsApp group for peer engagement and motivation.",[29,99],"Oral Health Behavior Change","NOT_YET_RECRUITING","2025-08-17",{"date":103,"type":39},"2025-08-24",{"date":105,"type":19},"2025-08-18",{"date":107,"type":19},"2026-02-18",{"name":109,"class":110},"Universiti Putra Malaysia","OTHER",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":56,"sex":15,"minAge":16,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":20,"phases":121,"briefSummary":122,"conditions":123,"keywords":128,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":146},"100570792","testing-and-comparing-the-impacts-of-mhealth-based-and-web-based-education-on-oral-cancer-100570792","NCT06711848","Testing and Comparing the Impacts of Mhealth-Based and Web-Based Education on Oral Cancer","A Comparative Analysis of the Effectiveness, Usability, Uptake, and Acceptability of an Educational Website and a Mobile Health Application Prototype in Improving Knowledge on Oral Cancer","Inclusion Criteria:\n\n* being a first-year bachelor degree student of either University of Rwanda (Rwanda), University of Peradeniya (Sri Lanka), Usmanu Danfodiyo University (Nigeria), University of Ibadan (Nigeria), or Saveetha University (India)\n* being within the age range of 18 to 39 years\n* having a personal smartphone\n* willingness to participate in the study\n\nExclusion Criteria:\n\n* being a member of staff or a visitor or a non-first year bachelor degree student of University of Rwanda (Rwanda), University of Peradeniya (Sri Lanka), Usmanu Danfodiyo University (Nigeria), University of Ibadan (Nigeria), or Saveetha University (India)\n* being a student of a tertiary institution not selected for the study\n* being below the age of 18 years or above the age of 39 years.\n* not having a personal smartphone\n* not willing to participate in the study","39 Years",{"count":120,"type":19},75,[22],"Introduction: Oral cancer is a malignant neoplastic disease affecting the lip, oral cavity (mouth) and\u002For the oropharynx. Despite the intense and diverse public health interventions on oral cancer prevention, the global prevalence rates of oral cancer and its major risk factors are still very high. Hence, oral cancer is an issue of serious global health importance.\n\nAim: To test and compare the effectiveness, usability, uptake, and acceptability of an educational website and a mobile health application prototype on oral cancer in improving oral cancer knowledge among university students.\n\nMethods: This study will adopt a randomised control trial design, and it will be conducted among 75 first-year bachelor's degree students from five universities across two continents: University of Rwanda (Rwanda, Africa), Usmanu Danfodiyo University (Nigeria, Africa), University of Peradeniya (Sri Lanka, Asia), University of Ibadan (Nigeria), and Saveetha University (India, Aisa). The study participants will be in three groups (Group 1, Group 2, and Group 3). The participants in Group 1 will be the control group (n = 25 participants; 5 participants from each university); that is the group that will not receive an educational intervention. However, those in Group 2 (n = 25 participants; 5 participants from each university) will receive a web-based educational intervention on oral cancer while those in Group 3 (n = 25 participants; 5 participants from each university) will receive an app-based educational intervention on oral cancer. Pretest survey and posttest survey will be done for all participants. The data collected will be statistically analysed using the Statistical Package for Social Sciences (SPSS) version 28 software. Descriptive statistics will be done for all variables while inferential statistics (analysis of variance) will be done to test for associations between variables of interest.\n\nConclusion: The findings of this study will determine the effectiveness, usability, uptake, and acceptability of the tested digital intervention tools.",[124,125,29,126,127],"Oral Cancer","Health Education, Community","MHealth Application","MHealth Intervention",[129,130,131,132,133,134,135,136],"mobile health","application","website","impact","knowledge","oral cancer","public health","intervention","2024-11-28",{"date":139,"type":39},"2024-12-02",{"date":141,"type":19},"2025-01-05",{"date":143,"type":19},"2025-04-30",{"name":145,"class":110},"University of Rwanda",5]