[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"diplegic-cerebral-palsy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:diplegic-cerebral-palsy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,71,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100605051","dual-task-training-with-vestibular-stimulation-in-children-with-diplegic-cerebral-palsy-100605051",false,"NCT07157488","Dual Task Training With Vestibular Stimulation in Children With Diplegic Cerebral Palsy","Inclusion Criteria:\n\n\\- Diagnosis of diplegic cerebral palsy (confirmed by physician\u002Ftherapist).\n\nAge between 6-12 years.\n\nGross Motor Function Classification System (GMFCS) levels II-III.\n\nAbility to walk with or without assistive devices.\n\nStable medical condition for the past 6 months.\n\nParental\u002Fguardian consent to participate.\n\nExclusion Criteria:\n\n* History of recent orthopedic surgery (within the past 6 months).\n\nBotulinum toxin injections within the past 6 months.\n\nSevere uncontrolled epilepsy or other uncontrolled medical conditions.\n\nSevere cognitive impairment preventing ability to follow instructions.\n\nSignificant visual, auditory, or vestibular disorders unrelated to cerebral palsy.\n\nParticipation in another interventional clinical study within the last 3 months.","ALL","6 Years","12 Years",{"count":19,"type":20},54,"ESTIMATED","INTERVENTIONAL",[23],"NA","Dual task training enhances gross motor function, reduce fatigue and minimize cognitive motor interference in children with diplegic cerebral palsy by promoting neuroplasticity and improving dual task processing. Vestibular stimulation improve balance triggering the vestibulospinal reflex, which play a key role in maintaining posture and reducing the risk of fall. Integrating dual task training with vestibular stimulation can provide a more holistic rehabilitation strategy by enhancing balance and posture stability through improved vestibular system activation, supporting motor and cognitive coordination by challenging the brain to handle tasks concurrently, and boosting functional mobility by mimicking everyday situations that require divided attention. This RCT evaluates its effectiveness in optimizing motor-cognitive integration, functional mobility and endurance compared to conventional motor training approaches.",[26],"Diplegic Cerebral Palsy",[28,29,30],"Diplegic cerebral palsy","Dual task training","Vestibular stimulation","NOT_YET_RECRUITING","2025-08-27",{"date":34,"type":35},"2025-09-05","ACTUAL",{"date":37,"type":20},"2025-09",{"date":39,"type":20},"2025-12",{"name":41,"class":42},"University of Lahore","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100600364","effectiveness-of-suit-therapy-with-dual-task-exercises-on-gross-motor-functions-and-walking-in-children-with-diplegic-cerebral-palsy-100600364","NCT07096531","Effectiveness of Suit Therapy With Dual Task Exercises on Gross Motor Functions and Walking in Children With Diplegic Cerebral Palsy","The Effectiveness of Suit Therapy With Dual Task Exercises on Gross Motor Functions and Walking in Children With Diplegic Cerebral Palsy","Inclusion Criteria:\n\n* Age from 6 to 12 years.\n* Both sexes.\n* A medical diagnosis of spastic diplegic CP made by pediatricians or pediatric neurologists.\n* Children with spasticity grades ranged from 1 to 2+ according to the Modified Ashworth scale (MAS).\n* Children who can sit on the chair with good balance and recognize and follow verbal orders and commands are included in both testing and training techniques.\n\nExclusion Criteria:\n\n* They had a permanent deformity (bony or soft tissue contractures).\n* Children having visual or auditory defects.\n* Current hospitalization for urgent medical reasons.\n* Severe mental retardation.\n* Children who will undergo fewer than twelve regular sessions of physical therapy at their place will not be included in the survey.\n* Children with a history of epileptic seizure or any diagnosed cardiac or orthopedic disability that may hinder assessment methods and treatment.",{"count":51,"type":20},30,[23],"This study aims to investigate the effect of suit therapy combined with dual-task training on gross motor performance and walking abilities in children with diplegic cerebral palsy.",[55,56,57,58,59,26],"Suit Therapy","Dual Task Exercises","Gross Motor Functions","Walking","Children","RECRUITING","2025-07-24",{"date":63,"type":35},"2025-07-31",{"date":65,"type":35},"2023-10-01",{"date":67,"type":20},"2025-09-30",{"name":69,"class":42},"Kafrelsheikh University",1,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":15,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":84,"conditions":85,"keywords":86,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":70},"100542501","immediate-effect-of-dafo-on-gross-motor-function-and-balance-in-diplegic-cerebral-palsy-100542501","NCT06343688","\"Immediate Effect of DAFO on Gross Motor Function and Balance in Diplegic Cerebral Palsy","Examination of the Instant Effect of DAFO Use on Balance and Lower Extremity Gross Motor Functions in Individuals With Spastic Diplegic Cerebral Palsy","Inclusion Criteria:\n\n* Diagnosed with Spastic Diplegic type of cerebral palsy\n* Age between 4 and 15 years\n* Using bilateral Dynamic Ankle-Foot Orthosis (DAFO)\n* Communication Function Classification System (CFCS) level between 1 and 2\n* Gross Motor Function Classification System (GMFCS) level between 1 and 2\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Having experienced lower extremity fractures or muscle-tendon and bone surgery in the past 6 months, or having undergone spinal or orthopedic surgery affecting the lower extremities\n* Exposure to any pharmacological agent or intervention inhibiting spasticity in the past 6 months.",true,"4 Years","15 Years",{"count":82,"type":20},38,"OBSERVATIONAL","\" Study will investigate the immediate effect of DAFO usage on balance and gross motor functions in individuals with spastic diplegic cerebral palsy. The study is planned to be conducted with children aged 4-15 who have GMFCS levels 1 and 2 and who are willing to participate along with their families at the Turkey Spastic Children Foundation Metin Sabancı Special Education and Rehabilitation Center. During the dates of the study, children who meet the inclusion criteria will be evaluated. Demographic information such as age, height, and weight will be obtained for the participating children. To classify the gross motor levels of the children, the Gross Motor Function Classification System (GMFCS), the Manual Abilities Classification System (MACS) for hand skills, the Communication Function Classification System (CFCS) for communication skills, and the Eating and Drinking Ability Classification System (EDACS) for feeding skills will be used. In addition, the Gross Motor Function Measure (GMFM-88) items D and E for assessing motor skills, the Wii Balance Board for testing balance, the Pediatric Berg Balance Scale, and the functional reach test will be utilized. The balance and gross motor functions of the included children will be assessed in two different ways: with and without DAFO. Data analysis will be conducted by a blinded statistician who is not part of the research team. IBM SPSS 26 (Statistical Package for Social Sciences) will be used for statistical analysis of the data. Normality of continuous variables will be assessed using the Kolmogorov-Smirnov test. If continuous variables follow a normal (parametric) distribution, paired sample t-tests will be conducted on pre-test and post-test data. If the data are non-parametric, Wilcoxon test will be used. Pearson chi-square test or Spearman correlation coefficient will be used to determine the relationship between variables based on assumptions. Results will be evaluated at a significance level of p \\\u003C 0.05 with a 95% confidence interval.\"",[26],[87,88,89,90,91],"cerebral palsy","Diplegia","Spastic","orthosis","balance","2025-02-05",{"date":94,"type":35},"2025-02-06",{"date":96,"type":35},"2024-04-01",{"date":98,"type":20},"2025-12-01",{"name":100,"class":42},"Abant Izzet Baysal University",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":15,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":114,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":127},"100578615","the-best-intervention-to-improve-gait-pattern-in-children-with-spastic-diplegic-cerebral-palsy-100578615","NCT06813599","The Best Intervention to Improve Gait Pattern in Children with Spastic Diplegic Cerebral Palsy","Effect of Motor Planning Exercises Versus Neurodevelopmental Technique on Gait Pattern in Children with Spastic Diplegic Cerebral Palsy","Inclusion Criteria:\n\n1. Parents\u002Flegals representatives consenting to their child's participation\n2. Diagnosis of cerebral palsy\n3. Ages 3-14 years - Cooperative behavior\n4. Their grade of spasticity will be from 1 to 2 according to Modified Ashworth scale\n5. They will be on Level I and II according to Gross Motor Functional Classification System\n6. The child will be able to follow verbal commands and instructions.\n\nExclusion Criteria: The children will be excluded if they have one of the following:\n\n1. Previous neurological or orthopedic surgery in the lower extremities.\n2. Botox injection in the lower extremities in the past 6 months.\n3. Fixed deformity in the joints of lower limb.\n4. Severe hearing and visual problems.\n5. Different diagnosis than cerebral palsy.\n6. Inability to \"walk freely or with a mobility aid (GMFCS Level IV or V)\" .\n7. Irregular attendance at assessments or therapy sessions.","3 Years","14 Years",{"count":51,"type":20},[23],"Cerebral palsy is the most common disability in childhood, is a devastating non-progressive ailment of the infants' brain with lifelong sequelae (e.g., spastic paresis, chronic pain, inability to walk, intellectual disability, behavioral disorders) for which there is no cure at present. Cerebral palsy has different causes such as perinatal asphyxia, stroke and central nervous system CNS infection.\n\nCerebral palsy may have several associated comorbidities, including epilepsy, musculoskeletal problems, intellectual disability, feeding difficulties, visual abnormalities, hearing abnormalities, and communication difficulties. There are different classifications of CP primarily based on motor type and topography one of them is diplegic CP, lower limbs are more seriously affected than the upper limb at times, patients have toe strolling because of a dorsiflexion problem of the foot and expansion in the tone of the lower leg. In serious cases, there is a flexion of the hips, knees and elbows, and when the child is held upward, the firmness of the lower furthest points is generally articulated and tightness of the adductor muscles of the lower legs cause scissoring of lower limits.\n\nNeurodevelopmental therapy NDT is a popular approach to rehabilitation for people with cerebral palsy. It focuses on improving movement by analyzing how the body moves, understanding the relationship between posture and movement, and using sensory information to guide motor control. NDT therapists often use techniques like handling to facilitate movement and train people to use more typical motor patterns. While NDT has been widely used, there's ongoing debate about its effectiveness compared to other approaches, and its specific practices can vary across different countries and settings.\n\nMotor planning is defined as either an explicit decision-making or implicit process that takes into consideration both the goal and the constraints of the desired movement . This process is thought to rely on a feedforward internal model based on action simulation . Before a motor command is sent, the system briefly perceives the environmental cues to anticipate the realization of an adapted movement . Through the representation of the sensorimotor associations learned from past experiences, a prediction of the sensory consequences of the action is made . This step appears before action initiation and is believed to be based on the copy of the motor command for a subset of tasks .\n\nMotor planning is a large concept encompassing terms such as anticipatory control, motor preparation, and motor programming, with the terminology changing over time and varying by field of study.\n\nMotor Planning Organization of Motor Actions Motor planning is the ability to automatically organize a motor act so that it can be performed or implemented. This involves the internal process of organizing one's motor actions, without consciously planning out the action is believed to be largely dependent on tactile proprioceptive sensory inputs, although visual perceptual and visual spatial skills are also often associated with this area of function. Most often, problems in motor planning are reflected in difficulties in planning body movements.",[26],[115,116,117,118],"CP","Diaplegic","motor planning","Gait pattern","2025-02-03",{"date":121,"type":35},"2025-02-07",{"date":123,"type":20},"2025-03-01",{"date":125,"type":20},"2025-07-01",{"name":69,"class":42},2]