[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"disc-disease-lumbar\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:disc-disease-lumbar":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100635923","mirror-image-spine-correction-exercises-versus-conservative-physiotherapy-for-lumbar-radiculopathy-100635923",false,"NCT07558993","Mirror Image Spine Correction Exercises Versus Conservative Physiotherapy for Lumbar Radiculopathy","Randomized, Parallel-Group, Superiority Trial of Mirror Image Spine Correction Exercises Versus Conservative Physiotherapy for Lumbar Nerve Root Microstructural Integrity Assessed by Diffusion Tensor Imaging in Adults With Lumbar Radiculopathy","MIRROR-LR","Inclusion Criteria:\n\n* Adults aged 18 years or older. Clinical diagnosis of unilateral lumbar radiculopathy. Presence of at least two of the following: dermatomal radiating leg pain, neurological deficit, positive neural tension test.\n\nMRI-confirmed lumbar nerve root compression or irritation consistent with symptoms.\n\nPain intensity of 3\u002F10 or greater. Able to undergo MRI and Diffusion Tensor Imaging (DTI). Able to understand study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Previous lumbar spine surgery. Bilateral radiculopathy or unclear diagnosis. Tumor, infection, fracture, inflammatory spinal disease, or cauda equina syndrome.\n\nSevere progressive neurological deficit requiring urgent treatment. Contraindications to MRI (pacemaker, incompatible implants, severe claustrophobia).\n\nRecent lumbar injections or surgery. Other neurological or musculoskeletal disorders affecting outcomes. Pregnancy if MRI contraindicated by local policy. Cognitive impairment or inability to follow instructions.","ALL","18 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","Lumbar radiculopathy is a common condition caused by irritation or compression of a lumbar nerve root, often resulting in radiating leg pain, numbness, weakness, and functional limitation. Conservative physiotherapy is commonly used as first-line treatment, but outcomes vary among patients.\n\nThis randomized controlled trial will compare Mirror Image Spine Correction Exercises with standardized conservative physiotherapy in adults with lumbar radiculopathy. Participants will be randomly assigned to one of two treatment groups for 12 weeks.\n\nThe primary outcome is lumbar nerve root microstructural integrity measured using Diffusion Tensor Imaging (DTI), including Fractional Anisotropy and other diffusion parameters. Secondary outcomes include pain intensity, disability, spinal alignment, and adverse events.\n\nThe purpose of this study is to determine whether a targeted posture-correction exercise approach provides greater improvement than conventional physiotherapy.",[27,28,29,30],"Radiculopathy","Radiculopathy Lumbar","Sciatica","Disc Disease Lumbar",[32,33,34,35,36,37,38,39,40,41],"Mirror Image Exercise","Physiotherapy","Diffusion Tensor Imaging","DTI","Conservative Physiotherapy","Low Back Pain","Nerve Root Compression","Postural Correction","Randomized Controlled Trial","Rehabilitation","NOT_YET_RECRUITING","2026-04-23",{"date":45,"type":46},"2026-04-30","ACTUAL",{"date":48,"type":21},"2026-09-01",{"date":50,"type":21},"2027-09-30",{"name":52,"class":53},"University of Sharjah","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":4,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":65,"briefSummary":66,"conditions":67,"keywords":68,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":54},"100495272","ultrasound-guided-microendoscopic-versus-fluoroscopic-guided-lumbar-transforaminal-epidural-steroid-injections-100495272","NCT05729022","Ultrasound-Guided Microendoscopic Versus Fluoroscopic-Guided Lumbar Transforaminal Epidural Steroid Injections","Ultrasound-Guided Microendoscopic Versus Fluoroscopic-Guided Lumbar Transforaminal Epidural Steroid Injections: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 64 years old of either sex\n* Disease status of American Society of Anesthesiologists grades I to II\n* Patients presenting with single-level disc disease and radiculopathy (L2-L3; L3-L4; L4-L5) for steroid injection\n* Confirmation of herniated disk by CT or MRI\n* Able to give informed consent\n\nExclusion Criteria:\n\n* Age under 18 or over 64 years old\n* Pregnant women\n* Disease status of American Society of Anesthesiologists grades III to IV\n* Unable to provide an informed consent\n* Radiculopathies at multiple spinal levels\n* Non-lumbar herniated discs\n* Clinically obvious or known spinal deformity or stenosis\n* Previous spine surgery\n* Local or systemic infection\n* Allergy to steroids, anesthetics, or contrast material\n* Uncorrectable coagulopathy and patients on anticoagulation therapy\n* Patients who refuse the procedure\n* Spine tuberculosis or tumors\n* Prior injections within 3 months","64 Years",{"count":64,"type":21},124,[24],"The purpose of this study is to compare the Microendoscopic combined with ultrasound technique to the standard routinely used X-ray guided transforaminal steroid injection technique.",[28,30],[69,70,71,72],"Epidural Injections","Lumbar Manipulation","Fluoroscopy","Ultrasound","2024-06-19",{"date":75,"type":46},"2024-06-21",{"date":77,"type":21},"2024-12-01",{"date":79,"type":21},"2025-12-01",{"name":81,"class":53},"American University of Beirut Medical Center"]