[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"disclosure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:disclosure":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100616277","ai-driven-consent-simplification-study-100616277",false,"NCT07303517","AI-Driven Consent Simplification Study","ACCESS: AI-Driven Consent Simplification Study","ACCESS","Inclusion Criteria:\n\nGroup 1:\n\n* Age 60 years and above\n* UCLA patient\n* English speaking\n* Ability to provide informed consent\n\nGroup 2:\n\n* UCLA investigators who are health providers that perform clinical trials\n* Must be clinical research investigatory and staff actively involved in research operations at UCLA\n* English speaking\n\nGroup 3:\n\n* Individuals involved in IRB activities (chairs, committee members, staff)\n* Must be a director or staff at UCLA\n* English speaking\n\nExclusion Criteria:\n\n* Group 1: None\n* Group 2: PI and co-PIs of the study \"Donor Chimerism and Graft Survival Following Combined HLA-Identical Sibling Living Donor Kidney and Hematopoietic Stem Cell Transplantation Utilizing a Conditioning Regimen of Total Lymphoid Irradiation (TLI) and Rabbit Anti-Thymocyte Globulin (rATG)\"\n* Group 3: Individuals from the IRB who have reviewed the study submission for \"Donor Chimerism and Graft Survival Following Combined HLA-Identical Sibling Living Donor Kidney and Hematopoietic Stem Cell Transplantation Utilizing a Conditioning Regimen of Total Lymphoid Irradiation (TLI) and Rabbit Anti-Thymocyte Globulin (rATG)\"",true,"ALL","18 Years",{"count":21,"type":22},230,"ESTIMATED","OBSERVATIONAL","The overarching goal of this pilot is to explore how generative artificial intelligence (genAI) can be used to improve the accessibility and understandability of informed consent materials in clinical research. The study will test the extent to which informed consent text can be improved by large language models (LLM; specifically, ChatGPT and NotebookLM) along with other AI tools (specifically, ElevenLabs) through qualitative and quantitative analyses.\n\nSimplifying such forms using genAI may facilitate better comprehension, ensuring truly informed consent. Improving informed consent form (ICF) comprehension can lead to more informed and willing participation in clinical studies. This improved understanding may result in higher enrollment rates, better subject retention, and more accurate data collection as individuals will have a clearer understanding of study procedures and risks.",[26,27,28,29],"Informed Consent","Comprehension","Communication","Disclosure",[31,32,33,34],"Informed Consent Readability","Plain language","Simplified consent forms","Research ethics","RECRUITING","2026-05-04",{"date":38,"type":39},"2026-05-08","ACTUAL",{"date":41,"type":39},"2026-01-08",{"date":43,"type":22},"2026-12-01",{"name":45,"class":46},"University of California, Los Angeles","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":5},"100545657","honest-open-proud-for-psychotic-and-bipolar-disorder-in-norway-100545657","NCT06384755","Honest Open Proud for Psychotic and Bipolar Disorder in Norway","Evaluation of a Norwegian Adaptation of the Honest Open Proud Program for Adults With Psychotic and Bipolar Disorders in an Outpatient Setting","HOP-NOR","Inclusion Criteria:\n\n* Diagnosed current psychotic (F 20) or bipolar disorder (F 30) according to International Classification of Diseases 10th Revision (ICD-10)\n* Age 18 to 65\n* Ability to provide written informed consent.\n* Fluent in Norwegian (needed for self-report measures)\n* Experience difficulties with stigma and disclosure regarding mental illness.\n\nExclusion Criteria:\n\n* Intellectual disability\n* Organic disorders","65 Years",{"count":58,"type":22},40,"INTERVENTIONAL",[61],"NA","The purpose of this pilot study is to evaluate the feasibility, acceptability and efficacy of a Norwegian adaptation of the group-based intervention 'Honest Open Proud' among adults with psychotic and bipolar disorders in an outpatient setting.",[64,65,29],"Psychotic Disorders","Bipolar Disorder",[67,68],"Honest Open Proud program","Psychotic and Bipolar disorders","2024-04-30",{"date":71,"type":39},"2024-05-02",{"date":73,"type":39},"2024-04-20",{"date":75,"type":22},"2026-12-31",{"name":77,"class":46},"Oslo University Hospital"]