[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"disease-activity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:disease-activity":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,39],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100621726","isthmin-1-as-a-biomarker-of-disease-activity-in-rheumatoid-arthritis-correlation-with-musculoskeletal-ultrasound-findings-100621726",false,"NCT07374367","Isthmin-1 as a Biomarker of Disease Activity in Rheumatoid Arthritis: Correlation With Musculoskeletal Ultrasound Findings","Serum Isthmin-1 Level as a Biomarker of Disease Activity in Rheumatoid Arthritis: Correlation With Musculoskeletal Ultrasound Findings","Inclusion Criteria:\n\n-Adult patients (≥18 years old) clinically diagnosed with rheumatoid arthritis according to the 2010 ACR\u002FEULAR classification criteria.\n\nExclusion Criteria:\n\n* Patients less than 18 years old.\n* Patients with other autoimmune diseases.\n* Participants with active infections, malignancies or diabetes.\n* Recent hand surgery, trauma, deformity and neurological conditions affecting hand function",true,"ALL","18 Years","65 Years",{"count":21,"type":22},66,"ESTIMATED","OBSERVATIONAL","The goal of this case control study is to detect serum isthmin-1 level in RA patient compered to healthy control . The main questions it aims to answer are:\n\nwhat is the serum isthmin-1 level in RA patient? what is the correlation between serum isthmin-1 and RA disease activity? what is the correlation between serum isthmin-1 level and MSUS finding in RA patients?",[26],"Disease Activity","NOT_YET_RECRUITING","2026-01-25",{"date":30,"type":31},"2026-01-28","ACTUAL",{"date":33,"type":22},"2026-05-01",{"date":35,"type":22},"2027-12-01",{"name":37,"class":38},"Amera Imam Abdel - Ghany Ahmed","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":46,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":48,"conditions":49,"keywords":52,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":66},"100588757","evaluation-of-intestinal-lesions-and-disease-activity-in-inflammatory-bowel-disease-based-on-18f-fapi-pet-imaging-100588757","NCT06945549","Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging","IBD，18F-FAPI","Inclusion Criteria:\n\n* Patients diagnosed with IBD according to clinical, imaging, endoscopic, and histopathological criteria;\n* Patients ≥18 years old;\n* 18F-FAPI PET\u002FCT intestinal imaging, conventional endoscopic and enhanced CT were performed within 1 week;\n* Intestinal segment matching was evaluated by endoscopy and imaging;\n* Patients voluntarily participate and sign informed consent.\n\nExclusion Criteria:\n\n* Pregnant or lactating patients;\n* Imaging images are of poor quality and cannot be used for diagnosis and evaluation;\n* Patients with contraindications for endoscopic or CT examination.",{"count":47,"type":22},30,"The goal of this observational study is to evaluate the role and effect of 18F-FAPI PET imaging in the identification of intestinal lesions and the assessment of disease activity in inflammatory bowel disease. The main question it aims to answer is:\n\nCan 18F-FAPI PET imaging effectively identify intestinal lesions in inflammatory bowel disease and accurately assess disease activity? Colonoscopy, enhanced abdominal CT, and 18F-FAPI intestinal imaging were completed within 1 week, and major adverse outcomes (MAO) were followed up 12 months after enrollment.\n\nLast updated on March 25, 2025",[50,26,51],"Inflammatory Bowel Disease (IBD)","FAPI",[53,54,55],"Inflammatory bowel disease","18F-FAPI PET","disease activity","RECRUITING","2025-06-25",{"date":59,"type":31},"2025-06-29",{"date":61,"type":31},"2025-04-25",{"date":63,"type":22},"2027-12-31",{"name":65,"class":38},"Daping Hospital and the Research Institute of Surgery of the Third Military Medical University",1]