[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"diseases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:diseases":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":4,"leadSponsor":41,"locationsCount":44},"100194349","oral-specimen-and-data-acquisition-study-of-subjects-requiring-third-molar-removal-100194349",false,"NCT01805869","Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal","* INCLUSION CRITERIA:\n* Ages greater than or equal to 16-50 years\n* Clinical evidence of need for third molar extraction as determined by medical, dental, and radiographic evaluation by a NIDCR oral surgeon\n* Willing to allow for the collection of extracted waste tissue (e.g., teeth, alveolar bone, excessive gingival tissue) to be used for research\n* In good general health as defined by the American Society of Anesthesiologists (ASA) status I or II\n* Able to understand and sign an informed consent\n\nEXCLUSION CRITERIA:\n\n* Pregnant or nursing women\n* Unable to have third molar extraction as determined by NIDCR surgeon\u002Fdentist, due to medical conditions (beyond ASA I or II), complexity of the surgery, or history that precludes safe outpatient conscious sedation. These clinical decisions will be based on the risks and benefits related to the surgery.",true,"ALL","16 Years","50 Years",{"count":20,"type":21},3000,"ESTIMATED","OBSERVATIONAL","Background:\n\n\\- The third molars (wisdom teeth) normally grow in during late adolescence or early adulthood. Many people need or choose to have these teeth removed with oral surgery. Normally, the removed teeth and tissue are thrown away as medical waste. However, oral health researchers want to collect the teeth and tissue for research. They also want to encourage dentists at the National Institutes of Health to improve their skills in oral surgery. This study will collect the teeth and tissue of people who need to have oral surgery to remove their wisdom teeth.\n\nObjectives:\n\n* To provide continued dental skills training for dentists at the National Institutes of Health.\n* To collect teeth and tissue samples following wisdom tooth removal surgery.\n\nEligibility:\n\n\\- Individuals between 16 and 50 who need to have their wisdom teeth removed.\n\nDesign:\n\n* This study will involve a minimum of three visits. There will be a screening visit, a surgery visit, and at least one follow-up visit.\n* Participants will be screened with a physical exam and medical history. A full dental exam with x-rays will be given to evaluate the need for surgery.\n* At the second visit, participants will have oral surgery to remove their wisdom teeth. The teeth and tissue removed during the surgery will be collected for study.\n* Participants will receive drugs to control the pain after surgery. They will also be able to contact a dentist if there are any problems.\n* Between 7 and 21 days after surgery, participants will have a followup visit to check the healing. If they are having no problems, this will be the last visit. If there are any postsurgery issues, they will be scheduled for additional visits as needed.",[25,26,27,28,29],"Stomatognatic","Tooth Diseases","Diseases","Tooth","Tooth Impaction",[31,32,33],"Third Molar","Specimen Acquisition","Natural History","RECRUITING","2026-06-27",{"date":37,"type":38},"2026-06-30","ACTUAL",{"date":40,"type":38},"2013-06-19",{"name":42,"class":43},"National Institute of Dental and Craniofacial Research (NIDCR)","NIH",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":44},"100524950","non-invasive-ventilation-assisted-fiber-optic-bronchoscopy-100524950","NCT06115395","Non-invasive Ventilation Assisted Fiber-optic Bronchoscopy","Efficacy and Safety of Using Non-invasive Ventilation Assisted Fiber-optic Bronchoscopy","Inclusion Criteria:\n\n* Patients who admitted to the pulmonology ward or intensive care unit with any (diagnostic and\u002For therapeutic) bronchoscopy indication.\n\n  1. Age 18 years or more.\n  2. Patients accepted to participate in the study.\n\nExclusion Criteria:\n\n* Patients with:\n\n  1. Cardiac or respiratory arrest.\n  2. Impaired consciousness or confusion.\n  3. Type II respiratory failure.\n  4. Hemodynamic instability.\n  5. Inability to cooperate or to protect the airway.\n  6. Vomiting, bowel obstruction, recent upper gastrointestinal tract surgery and esophageal injury.\n  7. Patients refusing participation in the study.\n  8. Patients unfit for NIV and or NIV mask.\n  9. Intubation and or invasive ventilation candidates.\n  10. Presence of contraindications for bronchoscopy procedure such as insufficient platelet number or coagulopathy.","18 Years","70 Years",{"count":55,"type":21},100,"INTERVENTIONAL",[58],"NA","The purpose of this study is the evaluation of using bi-level positive airway pressure ventilation in candidates for fiber-optic bronchoscopy regarding benefits and drawbacks.",[61,27],"Lung",[63,64],"non- invasive ventilation","fiber-optic bronchoscopy.","2025-05-07",{"date":67,"type":38},"2025-05-11",{"date":69,"type":38},"2020-07-25",{"date":71,"type":21},"2025-12-31",{"name":73,"class":74},"Mansoura University","OTHER"]