[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dislocation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dislocation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100574042","assessing-ai-supported-fracture-detection-in-emergency-care-units-100574042",false,"NCT06754137","Assessing AI-Supported Fracture Detection in Emergency Care Units","Evaluating the Cost-Efficiency and Workflow Impact of AI-Supported Fracture Detection in an Orthopedic Emergency Care Unit","Inclusion Criteria:\n\n* Presenting to the emergency department with an isolated injury or joint complaint\n* Patients able and willing to provide informed consent.\n\nExclusion Criteria:\n\n* Patients with injuries or complaints involving multiple body regions\n* Patients with prior imaging of the affected extremity or region within the past 6 months\n* Contraindications to X-ray imaging (e.g., pregnancy or severe instability)\n* Patients with other ongoing studies that may interfere with this study\n* Patients unable to provide consent due to cognitive impairment or language barriers without an available representative.","ALL",{"count":18,"type":19},4800,"ESTIMATED","INTERVENTIONAL",[22],"NA","Brief Summary The purpose of this study is to determine if artificial intelligence (AI) can assist doctors in detecting broken bones, effusions, dislocations and bone lesions more quickly and accurately in an emergency room setting. The study will also evaluate whether AI can save time and reduce costs in healthcare.\n\nThe main questions to be addressed are:\n\n* Does AI improve the accuracy of detecting broken bones\u002Fdislocations\u002Feffusions\u002Fbone lesions?\n* Can AI expedite the process of diagnosing broken bones\u002Fdislocations\u002Feffusions\u002Fbone lesions?\n* Does AI reduce healthcare costs by enhancing efficiency?\n\nTo investigate these questions, two groups of patients will be compared. One group will follow the traditional diagnostic approach, while the other group will utilize AI to assist in diagnosing X-rays.\n\nParticipants in the study will:\n\nUndergo standard X-ray imaging of injured arms or legs, as part of routine care.\n\nHave X-rays reviewed by doctors with or without AI support, depending on the assigned group.\n\nThe study will include patients of all ages presenting to the emergency room with an isolated injury or joint complaints. No additional tests or treatments beyond standard care will be involved.",[25,26,27,28],"Fractures, Bone","Effusion Joint","Bone Lesion","Dislocation",[30,31,32,33,34,35,36,37,28,27],"Artificial Intelligence","Fracture Detection","Emergency Care","Cost-Efficiency","AI-Assisted Diagnosis","Diagnostic Accuracy","Orthopedic Diagnostics","Effusion","RECRUITING","2026-01-20",{"date":41,"type":42},"2026-01-22","ACTUAL",{"date":44,"type":42},"2025-03-31",{"date":46,"type":19},"2026-04-30",{"name":48,"class":49},"Salzburger Landeskliniken","OTHER",{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":20,"phases":62,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100377494","phase-2-intranasal-dexmedetomidine-plus-ketamine-for-procedural-sedation-100377494","NCT04195256","Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation","Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation in Children: an Adaptive Randomized Controlled Non-inferiority Multicenter Trial","Ketodex","INCLUSION CRITERIA\n\nGeneral Criteria\n\n1. Provision of signed and dated informed consent form\n2. Stated willingness to comply with all study procedures and availability for the duration of the study\n3. Deemed by treating physician to require procedural sedation\n\nSpecific criteria\n\n1. Children presenting to the paediatric EDs of participating sites age 2-17 years\n2. Weighing up to and including 100 kg\n3. One of the following injuries:\n\n   * Closed forearm fracture\n   * Metacarpal or phalangeal fracture\n   * Dislocation of a shoulder or elbow\n   * Type II supracondylar fracture\n4. Expected to not require more than one dose of IV sedative medication if they were not in the trial (as determined by the procedure physician and not including cast or splint application).\n5. Both nares are fully patent\n6. Physician plans to sedate patient\n\nEXCLUSION CRITERIA\n\n1. Previous hypersensitivity reaction to ketamine or dexmedetomidine including rash, difficulty breathing, hypotension, apnea, or laryngospasm;\n2. Suspected globe rupture;\n3. Concomitant traumatic brain injury with intracranial hemorrhage;\n4. Uncontrolled hypertension;\n5. Nasal bone deformity or septal deviation;\n6. Poor English or French fluency in the absence of native language interpreter;\n7. American Society of Anesthesiologists (ASA) class 3 or greater;\n8. Previous diagnosis of schizophrenia or active psychosis as per the treating physician\n9. Neuro-cognitive impairment that precludes informed consent, assent, or ability to self-report pain and satisfaction;\n10. More than one fracture or dislocation requiring reduction;\n11. Hemodynamic compromise as per the treating physician;\n12. Glasgow coma score \\\u003C 15;\n13. Previous sedation with ketamine or hematoma block within 24 hours;\n14. Fracture is comminuted or associated with a dislocation;\n15. Participant has undergone a hematoma block within 24 hours;\n16. Obstructive sleep apnea\n17. Previous enrollment in the trial;\n18. Suspected pregnancy\n19. Congenital heart disease or known cardiac dysrhythmia\n20. Known or suspected hepatic impairment\n21. Known renal insufficiency\n22. Uncorrected mineralocorticoid deficiency","2 Years","17 Years",{"count":61,"type":19},400,[63,64],"PHASE2","PHASE3","Orthopedic injuries comprise more than 10% of ED visits in children and 25 to 50% of children will sustain a fracture before age 16 years. Distal radius fractures account for 20-32% of fractures in children, making them the most common fracture type. Between 20 and 40% of extremity fractures in children require a closed reduction, often necessitating procedural sedation and analgesia (PSA). Intravenous (IV) ketamine is the most commonly used sedative agent used to perform a closed reduction. However, children rate IV insertion as the most painful hospital experience, second only to the injury itself. IV insertion can be more technically difficult in children because of smaller veins and lack of cooperation, often leading to multiple IV attempts. A combination of intranasal (IN) dexmedetomidine plus ketamine (IN Ketodex) may provide effective sedation for children undergoing a closed reduction without the distress and pain related to IV insertion. A less painful experience has been found to correlate with child satisfaction which may reduce caregiver anxiety and improve the therapeutic relationship with the health care team. This study is a multi-centre, two-arm, randomized, blinded, controlled, non-inferiority trial designed to test the hypothesis that IN Ketodex is non-inferior to intravenous (IV) ketamine with respect to depth of sedation as measured using the Pediatrics Sedation State Scale (PSSS).",[67,28],"Fracture","2024-11-01",{"date":70,"type":42},"2024-11-05",{"date":72,"type":42},"2020-03-11",{"date":74,"type":19},"2026-12",{"name":76,"class":49},"Naveen Poonai",6,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":58,"studyType":90,"phases":4,"briefSummary":91,"conditions":92,"keywords":4,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":4},"100548810","virtual-reality-in-the-management-of-painful-or-anxiety-provoking-procedures-in-emergency-departments-100548810","NCT06425835","Virtual Reality in the Management of Painful or Anxiety-provoking Procedures in Emergency Departments","Virtual Reality in the Management of Painful or Anxiety-provoking Procedures in Emergency Departments: (Open Prospective Observational Study)","VR","Inclusion Criteria:\n\n* Patients aged 09 and 24 years\n* suturing a wound\n* changing a dressing\n* lumbar puncture,\n* peripheral venous line\n* blood test\n* intramuscular injection\n* reduction of a fracture\n* casting or plastering.\n\nExclusion Criteria:\n\n* impaired consciousness\n* epilepsy\n* wound\u002Finfection covering the helmet area\n* headache\n* intellectual\u002Fmental retardation\n* nausea, vomiting\n* patient already included in the protocol\n* pain requiring immediate medical attention. analgesic (VAS \\>5 and described as intolerable).","9 Years","24 Years",{"count":89,"type":19},300,"OBSERVATIONAL","Study and evaluate the effectiveness of virtual reality in pain management.",[93,28,94],"Pain and Anxiety","Suture","NOT_YET_RECRUITING","2024-05-21",{"date":98,"type":42},"2024-05-22",{"date":100,"type":19},"2024-08-15",{"date":102,"type":19},"2026-12-15",{"name":104,"class":49},"University of Monastir"]