[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"distal-radius-fracture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:distal-radius-fracture":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,19,0,[8,50,77,102,129,162,187,212,242,264,286,308,348,378,406,433,461,487,512],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100634333","wrist-injury-strengthening-exercise-wise-versus-usual-care-advice-for-improving-pain-and-function-100634333",false,"NCT07538323","Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function","Progressive Resistance and Flexibility Exercises Versus Usual Care Advice for Improving Pain and Function After Distal Radius Fracture in Adults Aged 50 Years or Over in Denmark: the WISE-DK Randomised Trial","WISE-DK","Inclusion Criteria:\n\n* Distal radius fracture treated surgically or non-surgically\n* Willing and able to give informed consent\n\nExclusion Criteria:\n\n* Injury is more than two months old\n* There is evidence that the patient would be unable to participate in therapy or a self-guided exercise program provided by a participating center or adhere to study procedures (including cognitive impairment and fracture\u002Fsurgery complications such as Complex Regional Pain Syndrome)\n* No e-mail address to receive electronic questionnaires\n* Open fractures with a Gustilo \\& Anderson grading \\>1","ALL","50 Years",{"count":20,"type":21},588,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice they would normally receive. The main question it aims to answer is:\n\n• Will participants who receive a therapist-supervised exercise program have better improvement in pain and function, as measured by the Patient Rated Wrist Evaluation questionnaire, six months after their injury?\n\nResearchers will compare these participants with those who receive usual care, which includes advice on self-management, to see if the supervised exercise program leads to greater recovery.\n\nParticipants will:\n\n* Either receive supervised exercise, with a therapy session of up to 60 minutes and two additional sessions of up to 30 minutes each in addition to usual-care, or they will receive solely usual-care, consisting of advice on self-management.\n* Complete questionnaires electronically at baseline, 3-months, and 6-months.",[27,28,29,30,31],"Distal Radius Fracture","Colles Fracture","Wrist Fracture","Wrist Fractures","Fracture Arm",[33,34,35,36],"Exercise","Therapy","Resistance training","Strengthening exercise","RECRUITING","2026-06-26",{"date":40,"type":41},"2026-06-30","ACTUAL",{"date":43,"type":41},"2026-05-12",{"date":45,"type":21},"2029-12",{"name":47,"class":48},"University of Aarhus","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":57,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":64,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":4},"100643961","kinesiophobia-and-functional-outcomes-in-distal-radius-fractures-100643961","NCT07668531","Kinesiophobia and Functional Outcomes in Distal Radius Fractures","Time-Dependent Changes in Kinesiophobia and Functional Outcomes in Conservatively Treated Distal Radius Fractures","Inclusion Criteria:\n\n* Age range: 18-65 years\n* Non-intra-articular extension (AO type A) distal radius fracture\n* Treatment with closed reduction and short arm cast\n* No complications during treatment (redisplacement, fracture failure, etc.)\n* Ability to cooperate and complete the questionnaire\n\nExclusion Criteria:\n\n* History of previous fracture or neurological pathology in the same extremity\n* Associated wrist, elbow, or shoulder injury\n* Cognitive impairment or serious psychiatric illness\n* Surgically treated distal radius fractures","FEMALE","18 Years",{"count":60,"type":21},100,[24],"Distal radius fractures are among the most common fractures in adults and are frequently treated with closed reduction and cast immobilization. Although fracture healing is generally successful, some patients may develop fear of movement (kinesiophobia) after cast removal because of pain, reinjury concerns, or reduced confidence in using the injured wrist.\n\nThe purpose of this study is to evaluate the level of kinesiophobia in adults with conservatively treated distal radius fractures and to investigate how kinesiophobia changes over time following cast removal. The study will also examine the relationship between kinesiophobia and functional recovery.\n\nParticipants will be assessed after cast removal and again at three months following injury. Kinesiophobia, pain intensity, hand and wrist function, range of motion, grip strength, and upper extremity disability will be evaluated using standardized assessment tools. The findings may help clinicians better understand the role of movement-related fear in recovery and support the development of rehabilitation strategies aimed at improving functional outcomes after distal radius fractures.",[27],[65,66],"Kinesiophobia","Functional Recovery","NOT_YET_RECRUITING","2026-06-19",{"date":70,"type":41},"2026-06-25",{"date":72,"type":21},"2026-07-19",{"date":74,"type":21},"2027-02-05",{"name":76,"class":48},"Ebru Aloğlu Çiftçi",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":87,"conditions":88,"keywords":89,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":101},"100502129","satisfaction-and-recovery-after-distal-radius-fracture-100502129","NCT05818241","Satisfaction and Recovery After Distal Radius Fracture","Study on the Immediate Recovery and Satisfaction After Distal Radius Fracture During the First Three Months- a PROM Based Observational Study With Day-to-day Records","Inclusion Criteria:\n\n* Unilateral distal radius fractures in patients without any other significant injuries regardless of ligament injuries and ulnar fractures.\n* Signed written consent\n\nExclusion Criteria:\n\n* Compound injuries\n* Open fractures\n* Patients with post traumatic function deficits at any level in the affected arm prior to the distal radius fracture.\n* Patients with function deficits in the affected arm due to other medical conditions (e.g. Parkinsons disease, Rheumatoid Arthritis)\n* Reduced mental capacity (e.g. dementia, substance abuse)",{"count":85,"type":21},300,"OBSERVATIONAL","Distal radius fracture is the most common fracture in Sweden, but little is known about the patient's experience of pain and hand function during the first three months after the injury. This observational study will provide detailed information on a daily basis regarding pain, use of analgesic drugs, use of splints and hand function as measured weekly by a condition-specific questionnaire.",[27],[90,91],"wrist function","recovery","2026-04-21",{"date":94,"type":41},"2026-04-24",{"date":96,"type":41},"2023-01-12",{"date":98,"type":21},"2028-04-01",{"name":100,"class":48},"Sahlgrenska University Hospital",2,{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":109,"enrollmentInfo":110,"targetDuration":112,"studyType":86,"phases":4,"briefSummary":113,"conditions":114,"keywords":116,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":101},"100615353","the-investigation-of-kinesiophobia-in-conservative-distal-radius-fractures-100615353","NCT07291505","The Investigation of Kinesiophobia in Conservative Distal Radius Fractures","Investigation of the Predictability of Kinesiophobia on Functional Outcomes in Conservatively Treated Distal Radius Fractures","Inclusion Criteria:\n\n* Having been treated conservatively with an isolated distal radius fracture diagnosis,\n* Having a cognitive level that allows one to understand assessment methods and apply instructions.\n\nExclusion Criteria:\n\n* Comorbid musculoskeletal-neurovascular injuries\n* Bilateral injuries","65 Years",{"count":111,"type":21},34,"18 Weeks","This study aimed to investigate the predictability of kinesiophobia on functional outcomes in conservatively treated patients with distal radius fractures. For this purpose, patients' level of kinesiophobia will be assessed using the Tampa Kinesiophobia Scale. To assess the functional status of patients, joint range of motion and upper extremity weight bearing measurements will be performed. Patients' functionality will be additionally assessed with the Patient Rated Wrist Evaluation Questionnaire.",[27,65,115],"Functional Status",[117,118,90,119],"Tampa Scale of Kinesiophobia","distal radius fracture","upper extremity weight bearing","2026-03-09",{"date":122,"type":41},"2026-03-10",{"date":124,"type":41},"2026-02-02",{"date":126,"type":21},"2026-12-30",{"name":128,"class":48},"Pamukkale University",{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":137,"sex":17,"minAge":58,"maxAge":138,"enrollmentInfo":139,"targetDuration":4,"studyType":22,"phases":141,"briefSummary":142,"conditions":143,"keywords":144,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":49},"100235749","hematoma-block-for-distal-radius-fracture-100235749","NCT02346929","Hematoma Block for Distal Radius Fracture","Comparison of Ultrasound-guided Hematoma Block and \"Blind\" Hematoma Block for Analgesia in Distal Radius Fractures","Hematoma Block","Inclusion Criteria:\n\n* Adult patient ≥ 18 years old presenting to the emergency department with complaint of distal radius fracture\n\nExclusion Criteria:\n\n* High acuity\u002Fdistress per the Attending ED physician\n* Altered mental status or intoxication\n* Aphasia, mental retardation, dementia, or insurmountable communication barrier\n* Acute psychiatric illness",true,"100 Years",{"count":140,"type":21},115,[24],"The purpose of this study is to determine the efficacy of ultrasound guided hematoma block versus traditional \"blind\" hematoma block for analgesia in distal radius fracture reduction.",[27],[145,146,147,148,149,150,151,152],"Hematoma block","distal radius fracture reduction","ultrasound","ultrasound guided hematoma block","traditional hematoma block for analgesia","bupivacaine","pain reduction","wrist fracture","2026-03-02",{"date":155,"type":41},"2026-03-03",{"date":157,"type":41},"2014-08",{"date":159,"type":21},"2027-12",{"name":161,"class":48},"Beth Israel Deaconess Medical Center",{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":137,"sex":17,"minAge":58,"maxAge":109,"enrollmentInfo":169,"targetDuration":4,"studyType":22,"phases":171,"briefSummary":172,"conditions":173,"keywords":174,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":185,"locationsCount":49},"100625768","home-based-photobiomodulation-effects-in-the-postoperative-period-of-distal-radius-fractures-100625768","NCT07426926","Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures","Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures: A Double-Blind, Randomized, Controlled Clinical Trial","Inclusion criteria:\n\n* Adults aged 18 to 65 years,\n* Both sexes,\n* Patients with isolated, closed distal radius fractures with displacement and surgical indication,\n* Surgical indication defined by instability criteria:\n* Dorsal tilt of the distal fragment \\>20°,\n* Radial shortening ≥10 mm,\n* Articular incongruity,\n* Dorsal comminution,\n* Fractures classified as Fernandez types I, II, or III,\n* Fractures classified as AO\u002FOTA types 2R3A2, 2R3A3, 2R3B, or 2R3C (except 2R3C3).\n\nExclusion criteria:\n\n* Previous wrist injuries, sequelae, or motor deficits due to neurological lesions,\n* Pathological fractures,\n* Ipsilateral fractures in other regions of the limb,\n* Neurovascular injury with sensory deficit at the fracture site,\n* Local or systemic contraindications to surgery or postoperative recovery,\n* History of photosensitivity,\n* Neurological and\u002For psychiatric disorders,\n* Proliferative or infectious skin lesions at the wrist region,\n* Pregnancy,\n* Surgical complications (neurological or vascular injuries, or fracture line extension) - excluded from analysis but reported.",{"count":170,"type":21},42,[24],"This double-blind, randomized controlled clinical trial aims to evaluate the adjuvant effect of home-based photobiomodulation (PBM) therapy on the rehabilitation of surgically treated DRFs combined with an unsupervised home exercise program. A total of 42 participants will be randomly allocated into two groups. The Control Group will undergo the standard surgical procedure, perform the prescribed home exercises recommended by the hospital service, and use an inactive LED plate (photobiomodulation device). The PBM Group will follow the same surgical and exercise protocols but will use an active PBM device. Home exercises will begin 24 hours after surgery and should be performed twice daily for a total of 12 weeks. The device will be applied once daily to the wrist for 12 minutes (6 minutes on the dorsal side and 6 minutes on the palmar side). The primary outcome will be functional wrist assessment using the QuickDASH (Quick Disabilities of the Arm, Shoulder, and Hand) questionnaire at 2 weeks. Secondary outcomes will include wrist range of motion, grip strength, wrist function, and pain (assessed using the PRWE-BR instrument), as well as fracture healing. Assessments will be performed at 2, 4, 6, and 12 weeks post-surgery, except for bone consolidation (assessed starting at week 4) and for pain and range of motion, which will also be evaluated at 24 hours.",[27],[175,176,177,178],"photobiomodulation","distal radius","locked volar plate","early mobility","2026-02-20",{"date":181,"type":41},"2026-02-23",{"date":183,"type":41},"2025-07-01",{"date":126,"type":21},{"name":186,"class":48},"University of Nove de Julho",{"id":188,"slug":189,"hasResults":11,"nctId":190,"briefTitle":191,"officialTitle":192,"acronym":4,"eligibilityCriteria":193,"healthyVolunteers":137,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":194,"targetDuration":4,"studyType":22,"phases":196,"briefSummary":198,"conditions":199,"keywords":200,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":49},"100489275","phase-1-impact-of-early-adl-participation-on-outcomes-post-drf-100489275","NCT05650996","Impact of Early ADL Participation on Outcomes Post DRF","The Impact of Early ADL Participation on Functional Outcomes Post Distal Radius Fracture","Inclusion Criteria:\n\nEnglish Speaking\n\nDRFs treated with a cast\n\nIndividuals over the age of 18\n\nLess than 3 weeks from DRF\n\nExclusion Criteria:\n\nIndividuals with pre-existing neurological conditions affecting the upper limb\n\nIndividuals with cognitive deficits that would limit the ability to correctly report information on outcome measures\n\nIndividuals with psychological deficits which would limit the ability to correctly report information on outcome measures\n\nIndividuals with multiple injuries to the affected upper limb\n\nIndividuals with multiple injuries to both upper limbs\n\nIndividuals requiring surgery to fixate the distal radius fracture\n\nPrior distal radius fracture involving the same wrist\n\nIndividuals receiving hand therapy for another injury at enrollment into study",{"count":195,"type":21},64,[197],"PHASE1","This study is a randomized controlled trial (RCT). This RCT which will study the effect of performing daily activities early after a distal radius fracture being treated conservatively in a cast. This study will have two groups. The experimental group will watch a video and be given a handout on how to perform daily activities with the hand of the injured wrist while in a cast and cast care. The control group will watch a video on cast care and be given a handout on cast care. Outcome measures will be taken at initial evaluation between 0-3 weeks, at 6 weeks, at 9 weeks, and at 3 months. Outcome measures will include the Michigan Wrist Evaluation, Visual Analog Pain Scale, Tampa Scale of Kinesiophobia-11 Scale, finger mobility testing, grip and pinch strength, and the 9 hole peg test to test fine motor coordination. Outcome measure scores will be compared between groups using a t-test statistical test. Outcome measure scores will also be tested within groups using a paired t-test.",[27],[201,202],"Activities of Daily Living","Patient Education","2026-02-10",{"date":205,"type":41},"2026-02-12",{"date":207,"type":41},"2023-04-18",{"date":209,"type":21},"2026-09-30",{"name":211,"class":48},"George Washington University",{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":218,"eligibilityCriteria":219,"healthyVolunteers":11,"sex":17,"minAge":109,"maxAge":4,"enrollmentInfo":220,"targetDuration":4,"studyType":22,"phases":222,"briefSummary":223,"conditions":224,"keywords":227,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":239,"locationsCount":241},"100596183","no-reduction-compared-to-closed-reduction-for-distal-radius-fractures-in-patients-over-65-or-older-100596183","NCT07042139","No Reduction Compared to Closed Reduction for Distal Radius Fractures in Patients Over 65 or Older","A Randomized Controlled Trial Comparing No Reduction to Closed Reduction for Distal Radius Fractures in Patients 65 Years and Older (DISCLOSE Trial): A Study Protocol","DISCLOSE","Inclusion Criteria:\n\n* Age 65 years or older\n* Independent living patients\n* Displaced distal radius fracture (AO\u002FOTA 23A\u002F23C) with 15-40 degree dorsal angulation, and\u002For of shortening of the radius for more than 2 mm.\n* Associated ulnar styloid fracture is permitted\n* Low energy injury, (fall from \\\u003C1 m)\n\nExclusion Criteria:\n\n* Patient unable to provide consent\n* Patients who are actively working in a paid position\n* Volar angulation, partial articular fractures (AO\u002FOTA 23B)\n* Concomitant fracture of the ulna proximal to the base of the styloid process\n* Associated fracture or dislocation in any other body part that would affect the use of the injured distal radius\n* Distal radius fractures in both arms\n* Open injury, Gustilo 2 or higher\n* No bony contact between the main fragments\n* High energy injuries",{"count":221,"type":21},532,[24],"DISCLOSE trial is a randomized controlled trial including 532 participants with low-energy distal radius fractures. The primary objective is to evaluate whether casting without prior closed reduction is equivalent to casting following closed reduction with respect to wrist-related pain and disability, as measured by the Patient-Rated Wrist Evaluation (PRWE) score at 12 months, in patients aged 65 years or older with a displaced distal radius fracture.\n\n* Primary endpoint will be PRWE at 12 months\n* Follow-up visits are scheduled at 3 and 12 months. 5-year follow-up will be considered as an exploratory endpoint",[27,225,226],"Casting","Closed Reduction",[118,228,229,230,231],"casting","closed reduction","nonoperative treatment","DISCLOSE trial","2026-01-19",{"date":234,"type":41},"2026-01-21",{"date":236,"type":41},"2025-08-01",{"date":238,"type":21},"2033-07-01",{"name":240,"class":48},"Tampere University Hospital",10,{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":109,"enrollmentInfo":249,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":251,"conditions":252,"keywords":253,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":49},"100619205","minimal-clinically-important-difference-of-the-push-off-test-100619205","NCT07341594","Minimal Clinically Important Difference of the Push-Off Test","Determination of the Minimal Clinically Important Difference of the Push-Off Test in Distal Radius Fractures","Inclusion Criteria:\n\n* Diagnosis of distal radius fracture (DRF) and treatment with either conservative or surgical methods\n* Voluntary participation\n* Age between 18 and 65 years\n* Having a cognitive level sufficient to understand the assessment methods and follow instructions\n\nExclusion Criteria:\n\n* Presence of concomitant musculoskeletal or neurovascular injuries in the affected extremity\n* Presence of a neurological, orthopedic, rheumatologic, or metabolic condition that could affect the affected extremity",{"count":250,"type":21},109,"The aim was to determine the minimal clinically important difference of the push-off test in distal radius fractures.",[27],[118,254,255],"minimal clinically important difference","the push-off test","2026-01-06",{"date":258,"type":41},"2026-01-14",{"date":260,"type":21},"2026-01-16",{"date":262,"type":21},"2026-06-12",{"name":128,"class":48},{"id":265,"slug":266,"hasResults":11,"nctId":267,"briefTitle":268,"officialTitle":269,"acronym":4,"eligibilityCriteria":270,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":271,"targetDuration":4,"studyType":22,"phases":273,"briefSummary":274,"conditions":275,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":277,"lastUpdatePostDateStruct":278,"startDateStruct":280,"completionDateStruct":282,"leadSponsor":284,"locationsCount":101},"100437443","quantitative-and-clinical-assessment-of-flexor-tendon-gliding-following-application-of-a-bioresorbable-hydrogel-a-prospective-randomized-study-in-patients-undergoing-distal-radius-fracture-repair-100437443","NCT04976335","Quantitative and Clinical Assessment of Flexor Tendon Gliding Following Application of a Bioresorbable Hydrogel: A Prospective, Randomized Study in Patients Undergoing Distal Radius Fracture Repair","Quantitative and Clinical Assessment of Flexor Tendon Gliding Following Application of a Bioresorbable Hydrogel: A Prospective, Randomized Study in Patients Undergoing Distal Radius Fracture Repair.","Inclusion Criteria:\n\n* Cognitively able to converse in English or in native language supported by a certified medical interpreter;\n* Diagnosed with a closed, distal radius fracture treated with open reduction and internal fixation using a volar distal radius plating system.\n\nExclusion Criteria:\n\n* open injury;\n* concomitant injury to the contralateral wrist;\n* history of flexor tendon repair involving one or both hands or wrists;\n* use of a trans-carpal fixation device (bridge plate or external fixator) that would preclude wrist motion post-operatively;\n* concomitant fracture \u002F injury to the thumb or index finger of one or both hands;\n* concomitant carpal tunnel release.",{"count":272,"type":21},50,[24],"The investigators will be evaluating the use of versawrap in the setting of distal radius fractures by placing membrane between plate and flexor tendons. Investigators will then evaluate tendon gliding morphology and number of tendon ruptures",[27,276],"Tendon Rupture","2025-09-30",{"date":279,"type":41},"2025-10-02",{"date":281,"type":41},"2021-09-13",{"date":283,"type":21},"2027-07",{"name":285,"class":48},"University of Colorado, Denver",{"id":287,"slug":288,"hasResults":11,"nctId":289,"briefTitle":290,"officialTitle":291,"acronym":4,"eligibilityCriteria":292,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":293,"targetDuration":4,"studyType":22,"phases":294,"briefSummary":295,"conditions":296,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":300,"lastUpdatePostDateStruct":301,"startDateStruct":303,"completionDateStruct":305,"leadSponsor":306,"locationsCount":49},"100463748","use-of-a-vibration-tool-for-postoperative-pain-control-in-distal-radius-fractures-100463748","NCT05318729","Use of a Vibration Tool for Postoperative Pain Control in Distal Radius Fractures","Application of a Unique Vibration Modality for Postoperative Pain Control in Patients With Distal Radius Fractures to Reduce Postoperative Pain and Opioid Use","Inclusion Criteria:\n\n* Patients with a distal radius fracture who have undergone an open reduction and internal fixation using a volar FCR approach with a single volar plate\n* Patients who can read, write, and follow direction in English\n* Willing to undergo occupational therapy at Northwestern Medicine's Hand Surgery clinic\n\nExclusion Criteria:\n\n* Patients undergoing oncologic surgery\n* Patients who undergo simultaneous surgery such as open carpal tunnel\n* Patients who only require closed reduction of distal radius fractures\n* Operative patients that require dorsal plate fixation or separate radial styloid plate fixation",{"count":60,"type":21},[24],"The purpose of this research study is to determine if using a vibration tool improves pain control after surgical treatment of distal radius fracture. Additionally, the investigators would like to determine if this tool has any impact on consumption of pain medications postoperatively.",[27,297,298,299],"Radius Fracture Distal","Radius; Fracture, Lower or Distal End","Postoperative Pain","2025-09-23",{"date":302,"type":41},"2025-09-29",{"date":304,"type":21},"2026-03",{"date":283,"type":21},{"name":307,"class":48},"Northwestern University",{"id":309,"slug":310,"hasResults":11,"nctId":311,"briefTitle":312,"officialTitle":313,"acronym":314,"eligibilityCriteria":315,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":109,"enrollmentInfo":316,"targetDuration":4,"studyType":22,"phases":318,"briefSummary":319,"conditions":320,"keywords":325,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":339,"lastUpdatePostDateStruct":340,"startDateStruct":342,"completionDateStruct":344,"leadSponsor":346,"locationsCount":49},"100597180","digital-aftercare-for-wrist-and-clavicle-fractures-100597180","NCT07055139","Digital Aftercare for Wrist and Clavicle Fractures","Comparison of Digital Versus Traditional Aftercare for Uncomplicated Distal Radius and Clavicle Fractures","DA-DRAC","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Surgically treated, uncomplicated distal radius or clavicle fracture\n* Use of a smartphone (iOS or Android)\n* Ability to understand German and complete study-related questionnaires\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Polytrauma or additional injuries to the same upper extremity\n* No access to or inability to use a smartphone\n* Cognitive, psychiatric, or language barriers impairing participation\n* Pregnancy\n* Inability or unwillingness to comply with the study protocol",{"count":317,"type":21},84,[24],"This prospective, two-arm, open-label clinical trial compares digital aftercare with traditional follow-up in adult patients after surgical treatment of uncomplicated distal radius or clavicle fractures. The primary objective is to assess functional recovery at three months, using the Patient-Rated Wrist Evaluation (PRWE) for wrist fractures and the QuickDASH for clavicle fractures. Secondary outcomes include range of motion, patient satisfaction, quality of life, complication rates, healthcare costs, and work disability. In the digital aftercare group, program adherence and user experience will also be evaluated through app usage data and a structured questionnaire. The study aims to determine whether digital aftercare is a clinically and economically equivalent alternative to standard in-person care.",[27,321,322,323,324],"Clavicle Fracture","Postoperative Care","Patient-Reported Outcome Measures (PROMs)","Upper Extremity Fractures",[118,326,327,328,329,29,330,331,332,333,334,335,336,337,338,322],"clavicle fracture","digital aftercare","app-based aftercare","App-Based Rehabilitation","Fracture Recovery","Functional Outcome","QuickDASH","PRWE","eHealth","Patient Satisfaction","Quality of Life","EQ-5D","Complication Rate","2025-06-27",{"date":341,"type":41},"2025-07-08",{"date":343,"type":21},"2025-09-01",{"date":345,"type":21},"2027-03-31",{"name":347,"class":48},"Luzerner Kantonsspital",{"id":349,"slug":350,"hasResults":11,"nctId":351,"briefTitle":352,"officialTitle":353,"acronym":4,"eligibilityCriteria":354,"healthyVolunteers":11,"sex":17,"minAge":355,"maxAge":356,"enrollmentInfo":357,"targetDuration":4,"studyType":22,"phases":359,"briefSummary":360,"conditions":361,"keywords":363,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":369,"lastUpdatePostDateStruct":370,"startDateStruct":372,"completionDateStruct":374,"leadSponsor":375,"locationsCount":4},"100595137","remeos-drillpin-for-fixation-of-distal-radius-fractures-in-children-100595137","NCT07028541","RemeOs™ DrillPin for Fixation of Distal Radius Fractures in Children","To Evaluate the Feasibility of the Clinical Application of Mg-based RemeOs™ DrillPin for Fixation of Fractures of the Distal Radius in Children From the Age of Over 5 and Under 14.","Inclusion Criteria:\n\n* Distal Radius Fractures\n* Written informed consent of the parent, oral agreement of the patient documented as informant consent of the child\n* Subject and parents have been informed of the nature of the study, agrees to participate and parent signs the approved consent form. • Female patients in childbearing age (female patients who have begun menstruation) perform a pregnancy test prior inclusion\n\nExclusion Criteria:\n\n* Pathological bone lesions (e.g. bone cyst or osteomyelitis)\n* Underlying diseases (kidney diseases, uncontrolled diabetes mellitus)\n* Polytraumatized patients\n* Suspicion of child abuse\n* Inability or unwillingness to give informed consent\n* Multiple fracture (excluding associated ulna fracture)\n* Open Fracture\n* Pregnancy (tested in all female patients who have begun menstruation)","5 Years","13 Years",{"count":358,"type":21},20,[24],"This is a pre-market, single-arm, open-label, monocenter clinical investigation evaluating the safety and performance of the magnesium (Mg)-based bioresorbable RemeOs™ DrillPin for surgical fixation of distal radius fractures in pediatric patients. The study will enroll 20 children aged over 5 and under 14 years to assess implantation success, early safety outcomes, and long-term effects on growth and bone healing.",[362,27],"Fracture Fixation, Internal",[364,365,366,367,368],"Distal radius","fracture","RemeOs","DrillPin","Biodegradable Implant","2025-06-11",{"date":371,"type":41},"2025-06-19",{"date":373,"type":21},"2025-09",{"date":159,"type":21},{"name":376,"class":377},"Bioretec Ltd.","INDUSTRY",{"id":379,"slug":380,"hasResults":11,"nctId":381,"briefTitle":382,"officialTitle":383,"acronym":384,"eligibilityCriteria":385,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":386,"targetDuration":4,"studyType":22,"phases":387,"briefSummary":388,"conditions":389,"keywords":390,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":397,"lastUpdatePostDateStruct":398,"startDateStruct":400,"completionDateStruct":402,"leadSponsor":404,"locationsCount":49},"100587671","early-strengthening-rehabilitation-training-for-post-operative-fracture-distal-radius-100587671","NCT06931418","Early Strengthening Rehabilitation Training for Post-operative Fracture Distal Radius","Randomized Controlled Trial for Post-operative Fracture Distal Radius Rehabilitation - The Early Motion Protocol Rehabilitation vs. Early Strengthening Study (EMPRESS Trial)","EMPRESS","Inclusion Criteria:\n\n* Aged 50 years or older\n* Diagnosed with an isolated closed injury, displaced, distal radius fracture (AO\u002FOTA Classification 23-A1-3, B1-2, C1-2) without articular comminution\n* Requires operative fixation\n* Able to give consent\n\nExclusion Criteria:\n\n* History of previous hand or wrist surgery\n* Neurological injury or pre-existing neurological conditions to the upper limb\n* Underlying osteoarthritis of the wrist\n* Unfit for surgical anesthesia\n* Subacute fractures with delayed presentation (\\>2 weeks since initial injury)\n* Unable to consent\n* Refuse surgical intervention\n* Unable to follow commands for rehabilitation\n* Fixation construct or injuries requiring immobilization after surgery, such as unfixed distal ulna head or shaft fractures that require splintage or distal radio-ulnar joint instability planned for immobilization",{"count":272,"type":21},[24],"The primary objective of this study is to demonstrate safety and efficacy of an early strengthening and passive mobilization rehabilitation program for post-operative distal radius fracture fixation surgery compared to current conventional rehabilitation.",[27],[391,392,393,394,395,396],"Distal radius fracture","Rehabilitation","Patient outcomes","Physiotherapy","Occupational therapy","Orthopaedic fracture repair","2025-04-22",{"date":399,"type":41},"2025-04-25",{"date":401,"type":41},"2024-05-22",{"date":403,"type":21},"2027-10-31",{"name":405,"class":48},"The University of Hong Kong",{"id":407,"slug":408,"hasResults":11,"nctId":409,"briefTitle":410,"officialTitle":411,"acronym":4,"eligibilityCriteria":412,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":413,"targetDuration":4,"studyType":22,"phases":414,"briefSummary":415,"conditions":416,"keywords":417,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":424,"lastUpdatePostDateStruct":425,"startDateStruct":427,"completionDateStruct":429,"leadSponsor":431,"locationsCount":49},"100581961","supracondylar-radial-nerve-block-guided-by-ultrasound-versus-hematoma-block-for-analgesic-management-in-closed-reduction-of-distal-radius-fractures-100581961","NCT06857110","\"Supracondylar Radial Nerve Block Guided by Ultrasound Versus Hematoma Block for Analgesic Management in Closed Reduction of Distal Radius Fractures\"","\"Supracondylar Radial Nerve Block Guided by Ultrasound Versus Hematoma Block for Analgesic Management in Closed Reduction of Distal Radius Fractures: a Randomized Controlled Clinical Trial\"","Inclusion Criteria:\n\n* Patients over 18 years old with skeletal maturity evidenced in the initial radiographs.\n* Patients with a radiological diagnosis of distal radius fracture\n* Patients whose clinical condition is considered acute (duration of symptoms less than one week).\n* Patients who have an indication for closed reduction as a definitive or initial management of their distal radius fracture\n* Patients treated at San Ignacio University Hospital in Bogotá, Colombia\n\nExclusion Criteria:\n\n* • Patients with bilateral distal radius fractures\n\n  * Patients with open distal radius fractures.\n  * Patients with another fracture in the same limb\n  * Patients in a state of intoxication or under the influence of psychoactive substances.\n  * Patients with hemodynamic instability that prevents prioritizing closed reduction as management.\n  * Patients with a known allergy to local anesthetics\n  * Patients on full-dose anticoagulant therapy.\n  * Patients who refuse to participate in the study\n  * Patients with cognitive, visual, or auditory impairments that prevent the proper completion of questionnaires",{"count":272,"type":21},[24],"Non-surgical treatment with closed reduction and immobilization using a splint or cast is the preferred approach for stable distal radius fractures, particularly in elderly patients. It is also the initial intervention for displaced fractures with a surgical indication before the procedure, aiming to reduce edema, manage pain, and prevent associated complications. However, the maneuvers required for bone reduction can cause significant pain, and there is still insufficient evidence to favor one anesthetic method over another. In recent years, there has been a trend toward utilizing local methods, such as hematoma block or ultrasound-guided supracondylar block of the radial nerve, due to their lower incidence of complications. Nonetheless, there are currently no studies comparing the efficacy of these two analgesic approaches.\n\nThis study aims to compare the analgesic effect of ultrasound-guided supracondylar block with that obtained through hematoma block in patients with distal radius fracture during closed reduction, using the Numeric Rating Scale. Additionally, it aims to compare the quality of the reduction through radiographic measures and assess the frequency of adverse events after the two interventions.",[27],[418,419,420,421,422,423],"Wrist fractures","closed fracture reduction","analgesia","Anesthesia, local","nerve block","pain measurement","2025-03-12",{"date":426,"type":41},"2025-03-17",{"date":428,"type":41},"2024-06-01",{"date":430,"type":21},"2025-06-30",{"name":432,"class":48},"Hospital Universitario San Ignacio",{"id":434,"slug":435,"hasResults":11,"nctId":436,"briefTitle":437,"officialTitle":438,"acronym":4,"eligibilityCriteria":439,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":440,"enrollmentInfo":441,"targetDuration":4,"studyType":22,"phases":443,"briefSummary":444,"conditions":445,"keywords":448,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":452,"lastUpdatePostDateStruct":453,"startDateStruct":455,"completionDateStruct":457,"leadSponsor":459,"locationsCount":49},"100575214","the-effects-of-whirlpool-and-contrast-bath-in-patients-with-complex-regional-pain-syndrome-after-distal-radius-fracture-100575214","NCT06769373","The Effects of Whirlpool and Contrast Bath in Patients with Complex Regional Pain Syndrome After Distal Radius Fracture","The Effects of Whirlpool Bath and Contrast Bath Treatments on Pain, Disability, Functionality and Grip Strength in Patients with Complex Regional Pain Syndrome After Distal Radius Fracture","Inclusion Criteria:\n\n* Patients with complex regional pain syndrome type-1 (CRPS-type 1) after distal radius fracture, who were followed conservatively (long\u002Fshort arm splint-cast) between the ages of 18-70, who applied to AFSU Physical Medicine and Rehabilitation Clinic. It is planned to use the Budapest diagnostic criteria for the diagnosis of CRPS Type 1.\n\nExclusion Criteria:\n\n* Orthopedic injuries (other accompanying orthopedic fractures, such as ulna fracture, carpal bone fractures),\n* Other system injuries,\n* Patients whose distal radius fractures were surgically treated,\n* Patients who had previously undergone surgery on the same upper extremity,\n* Nerve, tendon and artery injuries accompanying the fracture,\n* Other neurological, orthopedic or rheumatological problems affecting the same upper extremity,\n* Serious cardiovascular disease,\n* Presence of active infection, active dermatitis, skin diseases such as pemphigus, febrile diseases,\n* Presence of a fixed catheter in the area,\n* Impaired temperature sensationin in the area.","70 Years",{"count":442,"type":21},40,[24],"The aim of our study is to investigate the effects of whirlpool bath and contrast bath treatments on pain, disability, functionality and grip strength in patients with complex regional pain syndrome after distal radius fracture.",[27,446,447],"Complex Regional Pain Syndrome Type I","Complex Regional Pain Syndrome",[449,450,451],"Whirlpool","Contrast bath","hydrotherapy","2025-01-28",{"date":454,"type":41},"2025-01-30",{"date":456,"type":21},"2025-01-31",{"date":458,"type":21},"2025-06-15",{"name":460,"class":48},"Afyonkarahisar Health Sciences University",{"id":462,"slug":463,"hasResults":11,"nctId":464,"briefTitle":465,"officialTitle":466,"acronym":4,"eligibilityCriteria":467,"healthyVolunteers":11,"sex":17,"minAge":468,"maxAge":4,"enrollmentInfo":469,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":471,"conditions":472,"keywords":473,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":478,"lastUpdatePostDateStruct":479,"startDateStruct":481,"completionDateStruct":483,"leadSponsor":485,"locationsCount":49},"100491815","fracture-registry-university-hospital-basel-100491815","NCT05684042","Fracture Registry University Hospital Basel","Fracture Database of the University Hospital Basel: A REDCap Assisted Reliability and Validity Study of Fracture Classifications of the Distal Radius","Inclusion Criteria:\n\n* Patients at least 16 years of age and regardless of gender\n* Surgical treatment of a primary fracture of the distal radius was performed\n* Pre-therapeutic radiographs of good quality and in two planes\n* General consent for quality assurance and research was not rejected\n\nExclusion Criteria:\n\n* Existence of a documented refusal\n* Patients under the age of 16, as they are treated in the children's hospital\n* Conservative treatment of the distal radius fracture\n* Re-fracture after conservative or surgical treatment\n* Incorrect planes and poor quality of X-rays\n* Exclusive performance of a computed tomography, e.g. after polytrauma\n* Duplicates within the database\n* X-rays with forearm cast","16 Years",{"count":470,"type":21},216,"The primary goal of this research project is to measure the accuracy of the classifications of the distal radius fracture in the fracture database. The evaluation of the extracted data analyzes the validity of the fracture classifications that the medical staff carry out in everyday clinical practice.\n\nEndpoint of this project is the reclassification of the selected fractures by an in-house group of experts in order to be able to carry out a subsequent statistical evaluation. It is analyzed whether there are significant deviations between the classifications of the expert group and the fracture database.",[27],[474,475,476,477],"Fracture Database","Fracture Classifications of the Distal Radius","Quality assurance","REDCap","2024-12-06",{"date":480,"type":41},"2024-12-09",{"date":482,"type":41},"2022-06-09",{"date":484,"type":21},"2033-06",{"name":486,"class":48},"University Hospital, Basel, Switzerland",{"id":488,"slug":489,"hasResults":11,"nctId":490,"briefTitle":491,"officialTitle":492,"acronym":4,"eligibilityCriteria":493,"healthyVolunteers":11,"sex":17,"minAge":468,"maxAge":4,"enrollmentInfo":494,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":496,"conditions":497,"keywords":498,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":502,"lastUpdatePostDateStruct":503,"startDateStruct":505,"completionDateStruct":507,"leadSponsor":509,"locationsCount":49},"100459596","functional-outcome-after-epl-rupture-after-distal-radius-fracture-100459596","NCT05264675","Functional Outcome After EPL-rupture After Distal Radius Fracture","Functional Outcome After Suture or EIP-transfer in EPL-rupture After Distal Radius Fracture","Inclusion criteria:\n\n* Distal Radius Fracture\n* EPL-rupture\n\nExclusion Criteria:\n\n* comorbidity interfering with thumb function\n* inability to fill in forms",{"count":495,"type":21},60,"Rupture of the extensor pollicis longus, (EPL) is a common complication after distal radius fractures. A rupture prevents the thumb extension, which in turn has a negative impact on hand function. An EPL-rupture can either be surgically treated by primary suture, which means that the ends of the tendon are sutured. This is however not recommended if the tendon is weakened. In such cases the rupture can be treated by a transfer of, most often, extensor indicis proprius (EIP) to the thumb.\n\nDistal radius fractures are common and a rupture of the EPL-tendon is a known complication thar interferes with hand function and therefore more studies on this patient group are warranted.\n\nThe aim of this prospective study is to compare regaining of thumb function after surgery, with the non-injured side, after primary suture and EIP-transfer after EPL-rupture as a complication following distal radius fracture.",[27],[499,391,500,501],"EPL-rupture","Function","ADL","2024-11-13",{"date":504,"type":41},"2024-11-14",{"date":506,"type":41},"2022-01-01",{"date":508,"type":21},"2026-12-01",{"name":510,"class":511},"Vastra Gotaland Region","OTHER_GOV",{"id":513,"slug":514,"hasResults":11,"nctId":515,"briefTitle":516,"officialTitle":517,"acronym":518,"eligibilityCriteria":519,"healthyVolunteers":137,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":520,"targetDuration":4,"studyType":22,"phases":522,"briefSummary":523,"conditions":524,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":525,"lastUpdatePostDateStruct":526,"startDateStruct":528,"completionDateStruct":530,"leadSponsor":532,"locationsCount":4},"100452715","minimally-invasive-fixation-for-distal-radius-fractures-100452715","NCT05175118","Minimally Invasive Fixation for Distal Radius Fractures","Minimally Invasive Surgical Fixation for Unstable Fractures of the Distal End Radius in Adults","DRF","Inclusion Criteria:\n\n1. patients with unstable distal radial fracture\n2. skeletally mature Patients.\n3. Acute fractures within one weeks of injury\n\nExclusion Criteria:\n\n1. contaminated open fractures.\n2. fractures associated with vascular injury requiring repair, and suspected pathologic Fracture",{"count":521,"type":21},30,[24],"Minimally invasive surgery avoids the tissue damage and impairment of physiological function caused by open surgery because of its precise location techniques and can effectively promote the early recovery of wrist function. Under conditions of no cutting of fracture fragments, no blood supply compromise in the fracture fragments",[27],"2024-08-02",{"date":527,"type":41},"2024-08-05",{"date":529,"type":21},"2024-12-20",{"date":531,"type":21},"2025-10",{"name":533,"class":48},"Assiut University"]