[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"diverticular-diseases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:diverticular-diseases":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100614202","initial-safety-of-sfm-plus-otoloc-for-creating-side-to-side-or-end-to-side-colorectal-anastomoses-100614202",false,"NCT07276529","Initial Safety of SFM Plus OTOLoc for Creating Side-to-side or End-to-side Colorectal Anastomoses","Safety and Device Functionality of the Flexagon Self Forming Magnet Anastomosis Plus OTOLoc for Creating Ileo-colic, Colo-colonic and Colorectal Anastomoses in Patients Undergoing Surgical Procedures","Colonic","Inclusion Criteria:\n\n1. Aged 22 years or older at screening\n2. Candidate for surgery requiring Right of Left Hemicolectomy or Sigmoidectomy or Low Anterior resection with cardiac\u002Fmedical clearance for surgery\n3. Able to understand and sign informed consent document\n4. American Society of Anesthesiologists (ASA) score \\\u003C IV at time of procedure\n5. All cancer patients must have completed chemotherapy ≥2 months prior to procedure\n6. Lives, and intends to remain, within a 150-mile radius of study center for the duration of the study\n7. Able to refrain from smoking during study follow-up period\n\nExclusion Criteria:\n\n1. Known or suspected allergy to silicone, nickel, titanium or Nitinol\n2. BMI \\> 55 kg\u002Fm2\n3. Uncontrolled diabetes (defined as HbA1c \\>10%)\n4. Congenital or acquired anomalies of the GI tract, including atresia or malrotation that would inhibit passing of SFM magnet\n5. Participants with an acute diagnosis of obstructed or perforated colon cancer at the time of the Screening Visit\n6. Any documented conditions for which endoscopy and\u002For laparoscopy would be contraindicated or history of previous failed endoscopy that may suggest difficulty during endoscopic delivery of magnets\n7. History of recurrent small bowel obstructions.\n8. Coagulation deficiency not normalized by medical treatment or platelet count \\\u003C50,000\u002FµL\n9. Known moderate to severe renal disease (eGFR \\\u003C 44 milliliters per minute per 1.73m2) or ongoing dialysis\n10. Hyperkalemia \u002F hypercoagulability or prior Venus Thromboembolism \u002F Pulmonary Embolism\n11. Immunocompromised (e.g., active treatment for malignancies, hematologic malignancy, on immunosuppressive therapy, moderate or severe primary immunodeficiency, advanced or untreated HIV, active treatment with high-dose corticosteroids (i.e., 20 or more mg of prednisone or equivalent per day when administered for 2 or more weeks prior to surgery) or other immunosuppressive or immunomodulatory agents\n12. Congestive heart failure with ejection fraction \\\u003C35% or clinically significant arrhythmia (any rhythm disturbances except sinus tachycardia, sinus bradycardia or a sinus rhythm with premature atrial or ventricular complexes)\n13. Decompensated chronic obstructive lung disease\n14. Active or suspected infection at the surgical site or a CDC Class 3\u002Fcontaminated or Class 4\u002Fdirty-infected surgical wound.\n15. Contraindication to general anesthesia\n16. Breast-feeding, pregnant, or planning on becoming pregnant during the follow-up period\n17. Currently participating or has participated in another clinical trial within the past 30 days and is receiving\u002Fhas received an investigational drug, device, or biologic agent\n18. Contraindication to general anesthesia\n19. Participant is not appropriate for inclusion in the clinical trial, per the medical opinion of the Principal Investigator","ALL","22 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","The primary objective of this trial is to investigate the safety and effectiveness of the Flexagon 25mm SFM system plus OTOLoc when used to create a side-to-side Ileo-colic, Colo-colonic and side-to-side or end-to-side colorectal anastomoses in participants undergoing colon surgery. This will be evaluated via a composite safety\u002Feffectiveness endpoint of patient success defined as successful creation of the target anastomosis without placement procedure, device or target anastomosis related reoperation through 30 days.",[27,28],"Colorectal Cancer","Diverticular Diseases","RECRUITING","2026-04-09",{"date":32,"type":33},"2026-04-13","ACTUAL",{"date":35,"type":33},"2026-04-01",{"date":37,"type":21},"2026-08",{"name":39,"class":40},"GI Windows, Inc.","INDUSTRY",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":41},"100502983","robotic-versus-laparoscopic-colectomy-for-diverticulitis-100502983","NCT05829343","RObotic Versus LAparoscopic Colectomy for DIverticulitis.","RObotic vs LAparoscopic Colectomy for DIverticulitis. A Multicenter Observational Prospective Study.","ROLADI","Inclusion Criteria:\n\n* Age \\> 18 years\n* Elective or delayed urgency colorectal resection for left-sided DD\n* Fully minimally invasive (robotic or laparoscopic) procedures.\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Urgent resection for DD\n* Hybrid minimally invasive resection\n* Conventional open resection.","18 Years",{"count":52,"type":21},1450,"OBSERVATIONAL","Over the last decade there has been a growing interest toward the application of robotic approach for diverticular disease. The evidence available on the literature showed that robotic approach, compared to the laparoscopic surgery, offers significant advantages in terms of conversion rate and shortened hospital stay for the treatment of diverticular disease.\n\nThe investigators aimed at evaluating whether robotic colectomy may offer some advantages over the laparoscopic approach for surgical treatment of diverticular disease by analyzing a one year multicenter prospective study.\n\nPrimary objective is to evaluate if robotic approach reduce the rate of conversion to open approach compared to laparoscopic surgery. Secondary objective is to assess difference between the two approaches in terms of rate of intraoperative complication, postoperative morbidities (according with Clavien and Dindo Classification), hospital stay and at one year follow up. Inclusion criteria are: elective colectomy for complicated or non-complicated diverticular disease performed with laparoscopic or robotic approach and age between 18 and 90 years. Exclusion criteria are non-elective colectomy (emergency resection), open procedure, diverticular resection performed during other procedure (i.e. colectomy for cancer). Data will be collected in one year from the start of the study.\n\nDue to the lack of available evidence, it is impossible to draw definitive conclusions. With this study, the investigators hope to clarify the role of the robotic approach in the treatment of diverticular disease.",[28,56],"Diverticulitis",[58,59,60,61,62],"Diverticular Disease","Robotic surgery","Laparoscopic surgery","Minimal invasive surgery","Colorectal surgery","2025-01-26",{"date":65,"type":33},"2025-01-29",{"date":67,"type":33},"2023-06-01",{"date":69,"type":21},"2025-06-30",{"name":71,"class":72},"S.M. Misericordia Hospital","OTHER",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":4},"100520812","endoscopic-ultrasound--guided-hartmann-reversal-procedure-100520812","NCT06061432","Endoscopic Ultrasound- Guided Hartmann Reversal Procedure","Endoscopic Reconstruction of the Gastrointestinal Tract After Surgical Resection Procedures Within the Large Intestine (Hartmann's Procedure- Modification of the Method Facilitating the Restoration of Gastrointestinal Continuity)","EndoHARP","Inclusion Criteria:\n\n* participants of both sexes aged above 18 years\n* participants, who provided informed consent for such treatment\n* eligibility for Hartmann's procedure according to current medical knowledge based on evidence-based medicine.\n\nExclusion Criteria:\n\n* pregnancy, breastfeeding, or intention to become pregnant during the study\n* contraindications to electrosurgical instruments\n* allergy to any of the materials used in the study\n* participants with advanced cancer in the metastatic stage\n* participants ineligible for restoration of gastrointestinal continuity\n* participants ineligible for surgery\n* participants ineligible for general anesthesia",{"count":82,"type":21},100,[24],"The goal of this clinical trial is to learn about clinical usefulness endoscopic gastrointestinal anastomoses to restore the gastrointestinal continuity in patients with permanent colostomy after Hartmann procedure.\n\nThe main questions it aims to answer are:\n\n* is the endoscopic restore the gastrointestinal continuity procedure effective?\n* is this endoscopic procedure safe?",[86,28,87],"Colorectal Neoplasms","Inflammatory Bowel Diseases",[89,90,91,92,93,94],"colorectal surgery","endotherapy","anastomosis","endoscopic ultrasound","gastrointestinal continuity","Hartmann procedure","NOT_YET_RECRUITING","2023-09-24",{"date":98,"type":33},"2023-09-29",{"date":100,"type":21},"2023-12-01",{"date":102,"type":21},"2026-12-31",{"name":104,"class":72},"Nicolaus Copernicus University"]