[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"drive\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:drive":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100473585","depression-and-driving-100473585",false,"NCT05446805","Depression and Driving","The Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older Adults (Depression and Driving)","D&D","Inclusion Criteria:\n\n* Drive on average at least once per week\n* Has a valid driver's license\n* Willing to complete blood draw\n* Willing to complete either lumbar puncture or PET imaging\n* 65 years or older\n* Speaks English\n\nExclusion Criteria:\n\n* Not willing to complete blood draw and\u002For one other biomarker\n* Less than 65 years of age\n* Does not drive a vehicle\u002F is no longer actively driving","ALL","65 Years",{"count":20,"type":21},150,"ESTIMATED","OBSERVATIONAL","This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).",[25,26],"Depression","Drive","RECRUITING","2026-06-04",{"date":30,"type":31},"2026-06-08","ACTUAL",{"date":33,"type":31},"2021-06-17",{"date":35,"type":21},"2027-12-17",{"name":37,"class":38},"Washington University School of Medicine","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":51,"conditions":52,"keywords":55,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":39},"100545472","glycemic-excursions-in-patients-with-type-1-diabetes-mellitus-using-closed-loop-systems-100545472","NCT06382350","Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems","Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems (Insulin Pump and Continuous Glucose Monitor) Versus Conventional Treatment in Different Life Situations - an Observational Multicenter Study","SAFEDRIVE","Inclusion criteria\n\nStudy group:\n\n* type 1 diabetes\n* patients aged ≥18 year\n* diabetes duration ≥3 years\n* regularly driving (non-professional drivers only)\n* treated with insulin pump MiniMed 780 G for at least 6 months with closed-loop setting treatment\n* willing to fill in the study questionnaires\n* signed patient's informed consent form\n\nControl group:\n\n* type 1 diabetes\n* patients aged ≥18 years\n* diabetes duration ≥3 years\n* regularly driving (non-professional drivers only)\n* treatment with multiple daily injections (MDI) of insulin therapy and the use of CGM for at least 6 months\n* willing to fill in the study questionnaires\n* signed patient's informed consent form\n\nExclusion Criteria (for study and control groups)\n\n* professional drivers\n* pregnancy\n* inability to be present at the follow-up visit\n* inability to complete the study questionnaires\n* participation in another clinical study within the last 3 months","18 Years",{"count":50,"type":21},120,"The study aims to compare glycemic excursions during several life situations (such as periods of driving, periods of night sleep, periods of occupation, periods of physical activity, and periods of stress) in patients with type 1 diabetes treated with closed-loop system and multiple daily insulin dose therapy",[53,54,26],"Type 1 Diabetes Mellitus","Type 1 Diabetes Mellitus With Hypoglycemia",[56,57,58],"Type 1 diabetes mellitus","Driving","Closed-loop system","2024-06-02",{"date":61,"type":31},"2024-06-04",{"date":63,"type":31},"2024-05-29",{"date":65,"type":21},"2026-05",{"name":67,"class":38},"University Hospital, Motol"]