[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dyslexia-acquired\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dyslexia-acquired":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100609048","acquired-dyslexia-modeling-and-treatment-100609048",false,"NCT07209488","Acquired Dyslexia Modeling and Treatment","Evidence-based Modeling for Acquired Dyslexia Treatments","AMT","Inclusion Criteria:\n\n* Fluent in English as a first language pre-stroke by self report.\n* Normal or corrected-to-normal vision.\n* Normal or aided hearing.\n* Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan).\n* Impaired reading as confirmed by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III.\n\nExclusion Criteria:\n\n* Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke.\n* Severe apraxia of speech (determined by consensus judgment among speech-language pathologists).\n* History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders.\n* Inability to undergo, or provide a copy of, a post-stroke brain imaging scan.","ALL","18 Years","85 Years",{"count":21,"type":22},12,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.",[28,29],"Stroke","Dyslexia, Acquired",[31,32,33,34],"reading","computational model","treatment","therapy","RECRUITING","2026-05-05",{"date":38,"type":39},"2026-05-06","ACTUAL",{"date":41,"type":39},"2025-12-03",{"date":43,"type":22},"2026-09",{"name":45,"class":46},"Rutgers, The State University of New Jersey","OTHER",3,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100429735","neurofeedback-intervention-for-reading-deficits-in-subacute-stroke-100429735","NCT04875936","Neurofeedback Intervention for Reading Deficits in Subacute Stroke","Rehabilitation of Reading Deficits in Subacute Stroke Using Functional Magnetic Resonance Imaging (fMRI) Neurofeedback and Motor Imagery","ReadingNFB","Inclusion Criteria:\n\n* First-ever left-hemisphere stroke \\\u003C 3 months prior to study recruitment or healthy volunteer\n* Age: 18 - 80 years old\n* Fluent and literate in English prior to stroke\n* Reading deficits, defined as \\>3 errors on the Paragraphs test (subtests VIII, IX) of the Reading Comprehension Battery for Aphasia-2nd ed. (RCBA-2) in keeping with the healthy control accuracy criterion of 86-100% correct.\n\nExclusion Criteria:\n\n* Inability to consent or complete study tasks\n* Inability to undergo MRI (e.g., pregnancy, non-MRI compatible implants, claustrophobia)\n* A history of prior neurological disease (e.g., brain tumor, Alzheimer's disease)",true,"80 Years",{"count":59,"type":22},28,[25],"The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation. Using a novel brain imaging technique, called real-time functional magnetic resonance imaging (fMRI) neurofeedback combined with right hand motor imagery, this project will re-instate brain activity in the left language-dominant hemisphere. Stroke patients will practice modulating their own brain activity using fMRI neurofeedback signal and will select the most effective mental strategies that help them maintain brain activation patterns associated with better reading recovery.",[28,29],"2026-05-04",{"date":65,"type":39},"2026-05-08",{"date":67,"type":39},"2023-04-03",{"date":69,"type":22},"2027-06-30",{"name":71,"class":46},"Kessler Foundation",1]