[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dysphagia-following-cerebrovascular-accident\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dysphagia-following-cerebrovascular-accident":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100579669","transcutaneous-auricular-vagus-nerve-stimulation-for-treating-post-stroke-dysphagia-100579669",false,"NCT06827301","Transcutaneous Auricular Vagus Nerve Stimulation for Treating Post-stroke Dysphagia","Transcutaneous Auricular Vagus Nerve Stimulation Combined With Rehabilitation Therapy for the Treatment of Post-stroke Dysphagia","LOGIC","Inclusion Criteria:\n\n* Acute ischemic or hemorrhagic stroke (within 7 days of onset)\n* Dysphagia diagnosed by FEES with a Fiberoptic Endoscopic Dysphagia Severity Scale (FEDSS) score between 3 and 5\n\nExclusion criteria:\n\n* Pre-existing stroke dysphagia\n* Dementia or other medical conditions that may interfere with the study","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of the present project is to use transcutaneous auricular vagus nerve stimulation (t-VNS) for the treatment of dysphagia in acute stroke patients to improve swallowing function and reduce mortality and disability related to this condition.\n\n30 patients will be randomized into one of the two arms of the study:\n\n* REAL: real t-VNS + speech therapy\n* SHAM: t-VNS placebo + speech therapy. The experimental treatment consists in the association between t-VNS (real or placebo) and speech therapy exercises to improve swallowing functionality. Each patient will undergo a speech therapy rehabilitation session lasting approximately 40 minutes a day for 3 consecutive days, simultaneously with t-VNS on left ear.\n\nSwallowing function and clinical conditions will be evaluated before the intervention (baseline, T0), immediately after the intervention (T1) and 3 months after the intervention (T2).",[27],"Dysphagia Following Cerebrovascular Accident",[29,30,31],"vagus nerve stimulation","dysphagia","stroke","RECRUITING","2025-02-10",{"date":35,"type":36},"2025-02-14","ACTUAL",{"date":38,"type":36},"2024-11-23",{"date":40,"type":21},"2026-06",{"name":42,"class":43},"Campus Bio-Medico University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":55,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":44},"100531108","dysphagia-after-transesophageal-echocardiography-in-acute-stroke---follow-up-trial-100531108","NCT06195501","Dysphagia After Transesophageal Echocardiography in Acute Stroke - Follow Up Trial","Transoesophageal Echocardiography - Dysphagia Risk in Acute Stroke- TEDRAS 2 - Follow Up","TEDRAS2","Inclusion Criteria:\n\n* Acute cerebral infarction detected by cMRI or cCT\n* Indication for TEE\n* Neurological deficits\n* Written informed consent\n\nExclusion Criteria:\n\n* Cerebral hemorrhage\n* Contraindications to FEES (lack of alertness as well as lack of compliance)",{"count":54,"type":21},40,"2 Years","OBSERVATIONAL","The aim of the prospective observational TEDRAS - Follow-up Trial is to investigate the limitations of the initial TEDRAS - Trial in patients with acute Dysphagia is a common consequence from ischemic stroke and it correlates with an increased risk of pulmonary complications such as aspiration pneumonia and an increased mortality risk.\n\nTEDRAS-Trial (Transesophageal Echocardiography: Dysphagia Risk in the Acute Phase After Stroke; ClinTrial.gov identifier NCT04302883) was the first randomized and controlled trial to address the question of the extent to which TEE increases dysphagia risk in acute stroke patients. The results of the study confirmed the hypothesis that dysphagia severity worsens after TEE in the intervention group.\n\nThe aim of the prospective observational TEDRAS - Follow-up Trial is to investigate the limitations of the initial TEDRAS - Trial in patients with acute ischemic stroke.",[59,27],"Ischemic Stroke, Acute","2024-06-05",{"date":62,"type":36},"2024-06-06",{"date":64,"type":36},"2023-05-01",{"date":66,"type":21},"2025-08-31",{"name":68,"class":43},"University of Giessen"]