[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dyspnea-during-activity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dyspnea-during-activity":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100623238","phase-2-effect-of-ipratropium-bromide-on-eilo-100623238",false,"NCT07394036","Effect of Ipratropium Bromide on EILO","The Effect of Ipratropium Bromide on Exercise-Induced Laryngeal Obstruction (EILO) in Pediatric Patients","Inclusion Criteria:\n\n* Patients must be diagnosed with EILO confirmed by Continuous Laryngoscopy During Exercise\n* Patients must be able to complete exercise testing\n* Patients must report dyspnea\n* Patients must have given assent with parental consent, understand all study procedures, and comply with them for the entire length of the study.\n\nExclusion Criteria:\n\n* Patients that do not have EILO.\n* Patients who did not undergo diagnostic CPET with CLE.\n* Patients with hypersensitivity to atropine or its derivatives due to structural similarity with ipratropium bromide.\n* Patients with a history of atrial flutter and\u002For fibrillation\n* Patients taking anticholinergic medications that cannot be paused for 24 hours.\n* Unable to perform exercise tests\n* Current drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.\n* Inability or unwillingness of patient or parent\u002Flegally authorized representative to give written informed consent.","ALL","8 Years","17 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","The investigators propose a study that compares breathlessness and airway obstruction during intense exercise in 34 children and adolescents with Exercise-Induced Laryngeal Obstruction after breathing in ipratropium bromide or placebo. It is hypothesized that breathlessness and airway obstruction will be lower following breathing in ipratropium bromide compared with placebo.",[27,28],"Exercise-Induced Laryngeal Obstruction","Dyspnea During Activity",[27,30,31],"Shortness of Breath during Exercise","Ipratropium Bromide","NOT_YET_RECRUITING","2026-05-01",{"date":35,"type":36},"2026-05-05","ACTUAL",{"date":38,"type":21},"2026-06-01",{"date":40,"type":21},"2029-12-31",{"name":42,"class":43},"Cook Children's Health Care System","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":56,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":44},"100600830","sweep-shuttle-walking-test-for-exercise-evaluation-in-pulmonary-resection-100600830","NCT07102589","SWEEP: Shuttle Walking Test for Exercise Evaluation in Pulmonary Resection","Predictive Value of the Shuttle Walking Test for Postoperative Dyspnea in Chronic Respiratory Disease Patients Undergoing Lung Resection: A Prospective Observational Study","SWEEP","Inclusion Criteria:\n\n* \\- Age ≥ 40 years\n* Scheduled for surgical lung resection (e.g., for lung cancer or benign tumor)\n* Diagnosis of chronic respiratory disease (COPD, ILD, or bronchiectasis)\n* Able to perform Shuttle Walking Test (ISWT + ESWT) before surgery\n* Able to complete pre- and postoperative symptom questionnaires (dyspnea, EQ-5D)\n\nExclusion Criteria:\n\n* \\- Illiteracy or inability to read study materials\n* Inability to communicate in Korean\n* Decline or withdraw consent\n* Severe lower limb disability interfering with walking (e.g., fracture, paralysis)","40 Years",{"count":55,"type":21},100,"3 Months","OBSERVATIONAL","This is a prospective observational study that evaluates whether the Shuttle Walking Test (SWT) can predict postoperative symptoms, particularly dyspnea, in patients with chronic respiratory diseases undergoing lung resection.\n\nCurrently, tools such as DLCO or cardiopulmonary exercise testing (CPET) are used to assess surgical risk and exercise capacity before lung surgery. However, these tests are not always accessible due to equipment limitations or long waiting times. The SWT is a simpler, safer, and more cost-effective alternative that has been recently recognized as a new medical technology in Korea for evaluating exercise capacity.\n\nIn this study, patients with chronic lung diseases (such as COPD, ILD, or bronchiectasis) who are scheduled to undergo lung resection will perform the SWT before surgery. Their symptoms and quality of life will be assessed through questionnaires before and three months after the surgery. The goal is to determine whether SWT results can help predict postoperative dyspnea and provide useful information for preoperative risk stratification.",[60,61,62,63,28],"COPD","ILD","Bronchiectasis","Lung Cancer NOS","RECRUITING","2025-07-30",{"date":67,"type":36},"2025-08-04",{"date":69,"type":36},"2025-06-01",{"date":71,"type":21},"2026-05-31",{"name":73,"class":43},"Seoul National University Bundang Hospital"]