[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"early-childhood-caries-ecc\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:early-childhood-caries-ecc":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,39,72,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100636985","midwives-perspectives-on-oral-health-in-pregnancy-and-early-childhood-a-cross-sectional-online-survey-100636985",false,"NCT07572799","Midwives' Perspectives on Oral Health in Pregnancy and Early Childhood: A Cross-Sectional Online Survey","Perceived Role and Perspectives of Midwives in Oral Health of Pregnant Women and Young Children: A Cross-Sectional Online Survey","Inclusion Criteria:\n\n* Practicing midwives in Germany\n* Age ≥ 18 years\n* Consent to participate in the online survey\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Not currently working as a midwife\n* Students without completed professional qualification\n* No informed consent provided","ALL","18 Years",{"count":19,"type":20},200,"ESTIMATED","OBSERVATIONAL","This study aims to explore how midwives in Germany perceive their professional role in the context of oral health of pregnant women and young children.\n\nA nationwide, anonymous, non-interventional online survey will be conducted to assess self-perceived role, confidence in counseling, perceived barriers, information sources, and training needs.\n\nThe study is designed as an exploratory cross-sectional survey without hypothesis testing.",[24,25,26],"Oral Health in Pregnancy and Early Childhood","Early Childhood Caries (ECC)","Health Promotion by Midwives","NOT_YET_RECRUITING","2026-04-30",{"date":30,"type":31},"2026-05-07","ACTUAL",{"date":33,"type":20},"2026-05-01",{"date":35,"type":20},"2026-08",{"name":37,"class":38},"University Medical Center Goettingen","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100622332","efficacy-of-silver-diamine-fluoride-versus-nano-silver-fluoride-in-arresting-active-dentin-caries-in-primary-teeth-in-young-children-100622332","NCT07382245","Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children","Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Apparently healthy children.\n* Children with age ranged from 3-5 years from both genders.\n* Children who refused dental treatment with Frankl Behavior Rating Scale 1 and 2.\n* Children having molars with active dentin caries score (2,3,4) according to International Caries Detection and Assessment System- ICDAS II, detected by visual and tactile.\n* Parents\u002Fguardians accept treatment and write informed consent.\n\nExclusion Criteria:\n\n* Children with allergy to silver from their medical history.\n* Children with ulcerative gingivitis.\n* Children with primary molars with the following criteria:\n* Symptomatic\n* Involving the pulp\n* Presence of fistula or sinus\n* Presence of gingival inflammation and Pain on percussion\n* Close to exfoliation","3 Years","5 Years",{"count":49,"type":20},60,"INTERVENTIONAL",[52],"NA","Early childhood caries is a major public health problem affecting preschool children worldwide. Silver Diamine Fluoride is a well-established non-invasive treatment for arresting caries; however, it causes black discoloration of treated lesions. Nano-Silver Fluoride has been introduced as an alternative that may arrest caries without discoloration.\n\nThis randomized clinical trial aims to compare the efficacy of Silver Diamine Fluoride and Nano-Silver Fluoride in arresting active dentin caries in primary teeth and to assess discoloration, post-operative pain, and parental satisfaction over a 12-month follow-up period.",[25,55],"Active Dentin Caries in Primary Molars",[57,58,59,60,61],"Early Childhood Caries","primary molar","Nano-Silver Fluoride","Silver Diamine Fluoride","SDF","2026-01-25",{"date":64,"type":31},"2026-02-02",{"date":66,"type":20},"2026-01-30",{"date":68,"type":20},"2026-03-15",{"name":70,"class":38},"October University for Modern Sciences and Arts",1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":16,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":84,"conditions":85,"keywords":86,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":71},"100618357","caries-risk-in-children-treated-under-general-anesthesia-for-early-childhood-caries-100618357","NCT07330570","Caries Risk in Children Treated Under General Anesthesia for Early Childhood Caries","The Evaluation of Current Caries Risk in Children Treated Under General Anesthesia Due to Early Childhood Caries Between 2015-2020","Inclusion Criteria:\n\n* Pediatric patients who underwent dental treatment under general anesthesia for early childhood caries (ECC) at the Department of Pediatric Dentistry, Faculty of Dentistry, Aydın Adnan Menderes University between 2015-2020\n* Patients whose follow-up information (e.g., discharge summary, treatment plan) is accessible through clinical records\n* Individuals who provide written informed consent signed by their parents\u002Flegal guardians and assent from the child to participate in the study\n\nExclusion Criteria:\n\n* Individuals with medical conditions that may affect oral health, such as systemic diseases, immunodeficiencies, or chronic illnesses\n* Children with special healthcare needs or mental\u002Fphysical disabilities\n* Patients who do not cooperate during the examination or do not allow the completion of the oral examination",true,"6 Years","16 Years",{"count":83,"type":20},44,"This observational, cross-sectional study aims to evaluate the current caries risk profiles of children who underwent dental treatment under general anesthesia (GA) for early childhood caries (ECC) between 2015 and 2020 at Aydın Adnan Menderes University, Faculty of Dentistry. A minimum of 44 systemically healthy children will be included.\n\nCaries risk will be assessed using the Cariogram model, incorporating clinical parameters (DMFT\u002Fdmft, Plaque Index, Gingival Index, probing depth), salivary factors (stimulated flow rate, buffer capacity), and standardized questionnaires covering diet, fluoride exposure, socioeconomic status, and dental visit history. Data will be collected in a single visit, analyzed using SPSS.\n\nThe study aims to provide scientific evidence for long-term preventive strategies and oral health policies targeting high-risk pediatric populations treated under GA for ECC.",[25],[87,88,89,90],"General Anesthesia","Pediatric Dentistry","Cariogram","Caries Risk Factors","RECRUITING","2025-12-29",{"date":94,"type":31},"2026-01-09",{"date":96,"type":31},"2025-05-07",{"date":98,"type":20},"2026-07",{"name":100,"class":38},"Aydin Adnan Menderes University",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":79,"sex":16,"minAge":46,"maxAge":46,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":111,"conditions":112,"keywords":113,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":71},"100589676","analysis-of-salivary-proteins-in-young-children-as-an-device-to-improve-caries-risk-assessment-100589676","NCT06957509","Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment","Salivary Metaproteome as a Prediction Tool in Early Childhood Caries","DecodECC","Inclusion Criteria:\n\n* 3-year-old children residing in the areas served by Folktandvården Danderyd and Järva, respectively\n* Written consent, signed by both parents (guardians)\n\nExclusion Criteria:\n\n* children older than three years\n* medication intake, and antibiotic use at the time of examination\n* children who have consumed food, drink, or used oral hygiene products within 2 hours before the dental visit\n* children who appear uncooperative during saliva sampling",{"count":110,"type":20},100,"The goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for caries risk.\n\nThe main question to answer is:\n\n• Can the host´s salivary protein profile (expression and abundance) show a correlation with the caries prevalence between the individuals in the different study cohorts?\n\nTwo cohorts of children with different documented demographic characteristics in the region of Stockholm (Sweden) will be examined.\n\nParticipants will be asked to provide saliva samples and undergo clinical oral examinations conducted by trained dental practitioners.",[25],[114,115,116,117],"early childhood caries","saliva","metaproteins","caries risk assessment","2025-05-02",{"date":120,"type":31},"2025-05-04",{"date":122,"type":31},"2025-04-04",{"date":124,"type":20},"2027-12",{"name":126,"class":38},"Karolinska Institutet"]