[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"eating-disorders-in-adolescence\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:eating-disorders-in-adolescence":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,59,92,130],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":58},"100632819","feasibility-of-the-transitioned-framework-for-youth-and-young-adults-with-eating-disorders-100632819",false,"NCT07518641","Feasibility of the TransitionED Framework for Youth and Young Adults With Eating Disorders","TransitionED 3","Inclusion Criteria:\n\nYouth and Young Adults (YYA):\n\n* Currently receiving paediatric eating disorder care at a participating study site.\n* Age 16 years or or older (approaching age-based transition to adult-care)\n* Expressed interest in transitioning to adult eating disorder care or other appropriate adult mental health services\n* Identified by the clinical team as appropriate to begin formal transition planning (e.g., sufficient transition readiness and interest in ongoing care)\n* Able and willing to provide informed consent\u002Fassent (as applicable at the site) and participate in study procedures\n\nCaregivers:\n\n* One caregiver (e.g., parent\u002Flegal guardian) of a participating YYA\n* Able and willing to provide informed consent and participate in study procedures (including questionnaires and interviews)\n\nClinicians (intervention deliverers):\n\n* Patient facing clinician at a participating site who provides transition support for participating YYA\u002Fcaregivers and is responsible for delivering intervention components (e.g., joint meeting(s), communication\u002Fcoordination related to the transition).\n* Able and willing to provide informed consent and participate in study procedures (e.g., focus groups)\n\nImplementation Team Members:\n\n* Program leadership\u002Fmanagers\u002Fsenior clinicians at a participating site involved in implementation of the intervention at that site.\n* Able and willing to provide informed consent and participate in study procedures (e.g., focus group).\n\nExclusion Criteria:\n\nYYA:\n\n* Not receiving pediatric eating disorder care at a participating site.\n* Under age 16 years\n* Does not express interest in transitioning to adult eating disorder care or other appropriate adult mental health services.\n* Not identified by the clinical team as ready\u002Fappropriate to engage in formal transition planning during the study period (e.g., insufficient transition readiness or not currently at the transition-planning stage).\n* Unable to provide informed consent\u002Fassent or unable to participate in study procedures (e.g., due to significant cognitive\u002Fcommunication barriers as determined by the clinical\u002Fresearch team).\n\nCaregivers:\n\n* Not the caregiver of an enrolled YYA (only one caregiver per YYA is enrolled).\n* Unable to provide informed consent or participate in study procedures.\n\nClinicians and Implementation Team Members:\n\n* Not affiliated with a participating site or not in an eligible role as defined above.\n* Peripheral providers who may be involved in care but are not enrolled as participants (e.g., family physicians or adult providers who might attend a joint meeting).\n* Unable to provide informed consent or participate in study procedures.","ALL","16 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","Moving from pediatric (children's) health care to adult health care can be challenging for youth and young adults with eating disorders. Many young people and families report feeling unprepared, unsure of what to expect, and worried about losing support during this time. Gaps in care during this transition can increase stress and make recovery more difficult.\n\nThis study is testing a structured transition support program called the TransitionED framework. The goal is to see whether this program can be successfully used in real hospital settings and whether youth, caregivers, and clinicians find it helpful.\n\nThe TransitionED framework is designed to help youth and families prepare for the move to adult care. It includes:\n\n1. A transition planning package for youth\n2. A separate planning package for caregivers\n3. At least two guided transition meetings with a clinician\n4. A short \"Personal Transition Profile\" written by the youth to help new adult providers understand them better\n5. Optional virtual peer support sessions for youth and for caregivers\n6. Tools to help pediatric and adult providers communicate more clearly\n\nYouth who are 16 years or older and currently receiving care in a participating pediatric eating disorder program may be invited to join, along with one caregiver. Clinicians and program leaders will also take part to help deliver and evaluate the program.\n\nParticipants will complete surveys at the beginning of the study, about two months later, and six months after finishing the program. Some participants will also take part in interviews to share their experiences.\n\nThis study is focused on feasibility. That means the main goal is to learn whether this transition program is practical, acceptable, and workable in everyday clinical care. What we learn will help improve transition support for youth and young adults with eating disorders in the future.",[26,27],"Eating Disorders in Adolescence","Transition of Care",[29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45],"eating disorders","healthcare transitions","Transition to Adult Care","Adolescent health","Young adults","Paediatric to adult care","Continuity of care","Mental Health Services","Implementation science","Feasibility study","Mixed Methods","Clinical Practice guidelines","Transition readiness","TRAQ","Peer support","Eating disorder treatment","Knowledge translation","NOT_YET_RECRUITING","2026-04-02",{"date":49,"type":50},"2026-04-08","ACTUAL",{"date":52,"type":20},"2026-05",{"date":54,"type":20},"2028-03-31",{"name":56,"class":57},"McMaster University","OTHER",2,{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":11,"sex":16,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":4,"studyType":21,"phases":71,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":91},"100577029","evaluation-of-a-digital-school-based-intervention-for-the-primary-prevention-of-eating-disorders-in-pre-adolescents-preta-program-100577029","NCT06792981","Evaluation of a Digital School-Based Intervention for the Primary Prevention of Eating Disorders in Pre-Adolescents (PRETA Program)","Effectiveness and Cost-effectiveness of an Online School-based Program for Reducing Risk Factors in Pre-adolescents (PRETA): Protocol for a Cluster Randomized Controlled Trial","PRETA","Inclusion Criteria:\n\n* Enrolled in the fifth or sixth year of primary education.\n* Informed consent provided by the student's legal guardians and responsible teacher to participate.\n\nExclusion Criteria:\n\n* Significant comprehension difficulties that limit adequate participation in the program and questionnaires.","10 Years","13 Years",{"count":70,"type":20},1068,[23],"Background:\n\nEating Disorders (ED) are mental health conditions, characterized by pathological behaviors toward food intake or a persistent obsession with weight control. EDs have a high prevalence among pre-adolescents in developed countries and pose a significant economic burden. Preventive interventions targeting at-risk populations for ED have proven effective. The use of Information and Communication Technologies (ICTs) facilitates access to larger population groups while also reducing costs.\n\nObjectives:\n\n* Develop and validate a universally applied intervention (PRETA), mediated by ICTs, to reduce eating-disorder risk and modifiable risk factors, through cultural adaptation and adjustment of the POtsdam Prevention at Schools (POPS) Program to preadolescents.\n* Assess the efficacy of the PRETA Program through a randomized controlled trial (RCT).\n* Evaluate the efficiency of the PRETA Program from a social perspective. Methodology The PRETA Program uses 9 online sessions with interactive activities for pre- adolescents, plus education for their families and teachers.\n\nIts content includes addressing key factors in the development of ED, such as eating habits, beauty standards, and media literacy, as well as activities aimed at strengthening psychological dimensions (self-esteem, emotional regulation, problem-solving, psychological flexibility, and resilience) and social skills, including communication styles and distinguishing between jokes and bullying.\n\nThe study involves schools being randomly assigned to either the PRETA Program or regular health activities. The effect of the intervention will be evaluated 3 months after its start.",[26,74],"Food Addiction",[29,76,77,78,79,80],"school-based intervention","efficacy","efficiency","Universal Prevention Program","Online Health","RECRUITING","2025-09-15",{"date":84,"type":50},"2025-09-19",{"date":86,"type":50},"2025-03-10",{"date":88,"type":20},"2025-12-31",{"name":90,"class":57},"Servicio Canario de Salud",1,{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":98,"eligibilityCriteria":99,"healthyVolunteers":100,"sex":16,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":4,"studyType":105,"phases":4,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":58},"100598018","a-study-of-the-intestinal-microbiota-in-children-and-adolescents-with-eating-disorders-a-perspective-from-psychoneuroimmunology-100598018","NCT07066033","A Study of the Intestinal Microbiota in Children and Adolescents With Eating Disorders. A Perspective From Psychoneuroimmunology","Getting Into the Guts of Eating Disorders in Children and Adolescents. A Perspective From Psychoneuroimmunology.","PSYNIGED","Inclusion Criteria:\n\n* Age: 7-17.9 years\n* Diagnosis of Anorexia Nervosa, both restrictive (ANR) and binge-purging (ANBP) subtypes, Other Specified Feeding and Eating Disorders (OSFED), Avoidant\u002FRestrictive Food Intake Disorder (ARFID) according to DSM-V (APA, 2013).\n* Males and females\n* First episode or less than 1 year evolution since initial symptoms\n* Written informed consent by parent\u002Ftutor and also by the adolescent if age is more than 12 y.\n\nExclusion Criteria:\n\n* Comorbidities: Current infectious disease at admission; Severe neurodevelopmental disorders with impaired language development; Moderate or severe intellectual disability; Endocrine disorders such as diabetes mellitus or thyroid disease; Celiac disease; Suicidal behaviors in the previous 3 months.\n* Patients with previous unsuccessful treatments for more than one year.\n* Use of the following medications before entering the study: laxatives, anabolic steroids, immunosuppressant drugs, Helicobacter pylori eradication treatment, thyroid hormones or antibiotic treatment in the previous two months\n* Surgery in the previous month. Control group participants' exclusion criteria are the same plus the following: History with diagnosis of mental disease (including EDs). Current autoimmune or infectious disease.",true,"7 Years","18 Years",{"count":104,"type":20},158,"OBSERVATIONAL","The goal of this observational study is to learn if behavioral and psychological factors are associated with the intestinal microbiota composition and function in children and adolescents with eating disorders (ED). The main questions it aims to answer are:\n\n* Are there any differences between the microbiota composition and function in adolescent patients with eating disorders and healthy adolescents?\n* Are the dietary pattern and other lifestyle habits associated with the intestinal microbiota composition in patients with a recent onset eating disorder?\n* Is it possible to predict the treatment response at one year by looking at any of the psychological and biological factors measured in the patients at baseline?\n* Are there any differences in the intestinal microbiota among patients with different subtypes of anorexia nervosa (restrictive, binge-purging, atypical) or with avoidance\u002Frestrictive food intake disorder (ARFID)? Researchers will compare the results with those obtained from a group of healthy children and adolescents matched by sex and age to find out if the associations observed differ between ED and control participants.\n\nParticipants with ED will fill in different lifestyle questionnaires and psychological tests; they will also undergo anthropometrical measurements and will provide fecal and blood samples at baseline and one year later. Healthy participants will provide the same lifestyle information, anthopometrical measurements and stool and blood samples. They will only undergo the baseline evaluation.",[26,108],"Eating Disorders in Children",[110,111,112,113,114,115,116,117,118,119],"Eating disorders","psychopathology","intestinal microbiota","diettary pattern","neuroendocrine peptides","neurotransmitters","inflammation","short chain fatty acids","metagenomics","prognostic factors","2025-07-03",{"date":122,"type":50},"2025-07-15",{"date":124,"type":50},"2024-08-29",{"date":126,"type":20},"2027-08",{"name":128,"class":129},"Esther Nova","OTHER_GOV",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":16,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":4,"studyType":21,"phases":141,"briefSummary":142,"conditions":143,"keywords":148,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":91},"100549272","evaluation-of-a-new-treatment-program-for-adolescents-with-eating-disorders-minerva-program-100549272","NCT06431854","Evaluation of a New Treatment Program for Adolescents With Eating Disorders: MINERVA Program","The Efficacy, Efficiency, and Patient Experience of a New Intensive Treatment Program for Adolescents With High-complexity Eating Disorders: MINERVA","Inclusion Criteria for the prospective experimental group:\n\n* Patient diagnosed with an Eating Disorder (according to the DSM-5) through a semi-structured interview (K-SADS PL-5)\n* Aged between 12 and 17 years old\n* Both patients and parents are willing to participate in the study and sign the informed consent to accept participation\n* Patient with a poor response to treatment, defined as having one of the following two conditions:\n\n  1. undergoing over a year of treatment, including partial and total hospitalization, without symptom stabilization, experiencing severe psychological distress, eating symptomatology, comorbidities, or family dysfunction during this period (clinical improvement of at least 50 on the CGAS functioning scale) OR\n  2. undergoing more than three admissions without symptom stabilization (clinical improvement of at least 50 on the CGAS functioning scale).\n\n     Exclusion criteria for the prospective group:\n* Acute ED pathology and biological decompensation that require urgent pediatric attention or admission to an acute psychiatric ward.\n\nInclusion criteria for the retrospective control group:\n\n* Aged between 12 and 17 years old\n* Diagnosed with an Eating Disorder (according to the DSM-5)\n* Received treatment in Sant Joan de Déu between 2012 and 2022\n* Patient with a poor response to treatment, defined as having one of the following two conditions:\n\n  1. undergoing over a year of treatment, including partial or total hospitalization, without achieving stabilization of ED symptomatology (needing high-intensive treatment units i.e. not being able to follow individual treatment in external consultations) OR\n  2. undergoing more than three admissions without symptom stabilization once referred to partial hospitalization in less than one year, including a similar psychological state and characteristics as the first condition\n\nExclusion criteria for the retrospective control group:\n\n* Missingness of 20% or more of the required data","12 Years","17 Years",{"count":140,"type":20},120,[23],"The aim of this study is to investigate the efficacy, efficiency, and patient experience of a new intervention program on adolescents with high-complexity eating disorders (ED). A prospective group of adolescents with ED (N=60) will follow this treatment program including four different phases: 1) Inpatient treatment; 2) Family Treatment Apartment; 3) Home Treatment; 4) Recovery within the community. The investigators will use a retrospective, control group (N=60) that matched the prospective group in age, sex, ED diagnosis, and severe symptomatology. Primary variables regarding Body Mass Index (BMI), ED symptomatology, functionality, recovery (yes\u002Fno), type of outpatient services (low\u002Fmid\u002Fhigh intensity), number of readmissions, and patient experience will be assessed at discharge, and after 6 and 12 months. Secondary variables include anxiety, depression, readiness to recover, quality of life symptoms, caregiver skills, and functionality of the family",[26,144,145,146,147],"Anorexia Nervosa","Bulimia Nervosa","Binge-Eating Disorder","Other Specified Feeding or Eating Disorder",[149,150,151,152,153,154,155,156],"Eating Disorders","Adolescence","Inpatient treatment","Home treatment","Cognitive Behaviorial Therapy","Family-Based Treatment","Dialectical Behavioral Therapy","Systemic Family Treatment","2024-05-21",{"date":159,"type":50},"2024-05-29",{"date":161,"type":50},"2023-10-23",{"date":163,"type":20},"2026-12",{"name":165,"class":57},"Fundació Sant Joan de Déu"]