[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ectopia-lentis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ectopia-lentis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100600371","efficacy-of-visual-and-perceptual-training-on-visual-function-for-operative-congenital-ectopia-lentis-children-100600371",false,"NCT07096622","Efficacy of Visual and Perceptual Training on Visual Function for Operative Congenital Ectopia Lentis Children","Efficacy of Visual and Perceptual Training on Visual Function for Operative Congenital Ectopia Lentis Children: A Randomized Controlled Clinical Trial","Inclusion Criteria\n\n1. Aged 4-12 years, with no gender restriction;\n2. Diagnosed with congenital ectopia lentis;\n3. Underwent bilateral lensectomy combined with IOL scleral fixation, and within 1 month ± 1 week after the second-eye surgery;\n4. Best-corrected visual acuity (BCVA) of unilateral or bilateral eyes is no worse than 20\u002F200 but below the normal level for the corresponding age: for 4-year-old children, BCVA ≤ 20\u002F40; for children aged 5 years and above, BCVA ≤ 20\u002F30;\n5. Written informed consent signed by the patient and their parents or legal guardians.\n\nExclusion Criteria\n\n1. History of ocular trauma or previous ocular surgery other than the study-related procedure;\n2. Unable to cooperate with treatment, examinations, and follow-up assessments;\n3. Complicated with recurrent lens dislocation, severe cataract (dense, axial, opacity diameter \\>3 mm and affecting central vision), secondary glaucoma, corneal endothelial decompensation, retinal detachment, or other conditions requiring urgent surgical intervention;\n4. Presence of diplopia in either eye;\n5. Known history of neurological disorders (e.g., photosensitive epilepsy);\n6. Participation in other clinical trials within the postoperative period that may affect the outcomes of the present study;\n7. Use of topical or systemic medications that may cause visual impairment, or other vision therapies other than refractive correction in the past 3 months (e.g., atropine penalization, occlusion therapy, digital therapy, Bangerter filters, optical suppression, VR training, etc.).","ALL","4 Years","12 Years",{"count":20,"type":21},82,"ESTIMATED","INTERVENTIONAL",[24],"NA","This is a multi-centre, open-label, parallel-group randomized controlled trial with the following objectives: Firstly, the investigators aim to evaluate the efficacy of web-based visual and perceptual training therapy on visual function in children with postoperative congenital ectopia lentis. Secondly, the investigators target to investigate the in stereoacuity, quality of life scores, and treatment compliance following visual and perceptual training intervention. Thirdly, to explore the safety profile of visual and perceptual training therapy software in this specific patient population. Lastly, this study aims to provide evidence-based recommendations for visual rehabilitation training strategies in children with postoperative congenital ectopia lentis in the Chinese population.",[27,28],"Ectopia Lentis","Lens Subluxation or Dislocation","RECRUITING","2026-04-21",{"date":32,"type":33},"2026-04-27","ACTUAL",{"date":35,"type":21},"2026-06-01",{"date":37,"type":21},"2029-06-30",{"name":39,"class":40},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},"100489508","follow-up-study-on-visual-prognosis-and-complications-of-ectopia-lentis-lens-100489508","NCT05654025","Follow up Study on Visual Prognosis and Complications of Ectopia Lentis Lens","Inclusion Criteria:\n\n* Diagnosed with congenital lens dislocation and age ≥ 3 years old.\n* Agree to participate in this study with written informed consent from patients or legal guardians.\n\nExclusion Criteria:\n\n* History of ophthalmic trauma or other ophthalmic surgeries.\n* Combined with other ophthalmic diseases such as primary glaucoma, uveitis and corneal disease.\n* Patients who could not cooperate in the examinations.",true,"3 Years",{"count":50,"type":21},604,"OBSERVATIONAL","This is a single-centre, observational cohort study with the following objectives: Firstly, the investigators aim to evaluate the vision-related quality of life and mental health status in congenital ectopia lentis patients. Secondly, the investigators target to investigate the correlations between genotype and clinical phenotype in patients of congenital ectopia lentis. Thirdly, to explore the metabolic profiles in the aqueous humor (AH) of patients with congenital ectopia lentis. Lastly, this study aims to explore the longitudinal changes of ocular biological parameters and complications in patients with postoperative congenital ectopia lens in the Chinese population.",[27,54],"Dislocation, Lens","2024-08-06",{"date":57,"type":33},"2024-08-07",{"date":59,"type":33},"2022-12-05",{"date":61,"type":21},"2027-12",{"name":39,"class":40},1]