[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ectopic-pregnancy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ectopic-pregnancy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,40,77,102,128,150,176,202,227,247,270,294,313],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100637912","phase-2-letrozole-versus-methotrexate-for-management-of-undisturbed-ectopic-pregnancy-100637912",false,"NCT07624903","Letrozole Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy","Inclusion Criteria:\n\n* Confirmed ectopic pregnancy on trans vaginal ultrasound\n* Age between 20 and 35 years\n* A β-hCG levels \\\u003C 3000 Iu\u002F L\n* The average diameter of the adnexal mass ≤3.5 cm\n* Stable hemodynamic condition\n\nExclusion Criteria:\n\n* Presence of fetal heart pulsation\n* Heterotopic pregnancy\n* Presence of significant abdominal pain\n* history of allergic reactions to MTX or letrozole\n* Any known liver disorder or abnormal liver enzyme levels (AST or ALT )\n* Any known renal disorder or impaired renal function tests (abnormal creatinine)","FEMALE","20 Years","35 Years",{"count":19,"type":20},70,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","The aim of work is to study the effectiveness of letrozole in treatment of early undisturbed ectopic pregnancy in comparison with Methotrexate.",[26],"Ectopic Pregnancy","NOT_YET_RECRUITING","2026-05-30",{"date":30,"type":31},"2026-06-03","ACTUAL",{"date":33,"type":20},"2026-06",{"date":35,"type":20},"2027-07",{"name":37,"class":38},"Kafrelsheikh University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":53,"conditions":54,"keywords":59,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":39},"100563413","randomized-study-of-a-dematerialized-management-for-post-emergency-gynecological-follow-up-100563413","NCT06615843","Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-Up","GYNAB","Inclusion Criteria:\n\n* Women aged 18 and 60 years\n* No consultation at the gynecological emergency department in the previous month and\u002For for the same pregnancy.\n* Requires post-emergency follow-up for one of the following clinical conditions:\n\n  * Genital Infections (IGH): Acute pelvic pain with or without leucorrhea requiring antibiotic treatment\n  * Ectopic Pregnancy (GEU): Non-complicated, not ruptured, no significant effusion on ultrasound, GEU \\< 4 cm, no cardiac activity if embryo present, stable hemodynamic state, HCG \\< 5000, compliant patient, no contraindications for Methotrexate\n  * Early Pregnancy of Uncertain Viability (GLI): Early stage with a positive bHCG test, no visible gestational sac on ultrasound, no effusion, bHCG \\< 1500 IU\n  * Missed Miscarriage (GAM): Confirmed by an intrauterine gestational sac ≥ 25mm without an embryo or an intrauterine gestational sac with an embryo ≥ 7mm without visible cardiac activity, treated with Misoprostol\n  * First Trimester Bleeding (MTRt1): Moderate vaginal bleeding with an ongoing intrauterine pregnancy without hemodynamic instability\n  * Hyperemesis Gravidarum (VG): Severe vomiting before 12 weeks of pregnancy without severe criteria necessitating emergency follow-up\n\nExclusion Criteria:\n\n* Severe clinical intolerance, defined by:\n\n  * Signs of severe sepsis with unstable hemodynamics (TA with SBP \\\u003C 90 mmHg and FC ≥ 105 bpm)\n  * Abdominal defense or contracture\n  * Pain not controlled by level 1 analgesics (EVA \\\u003C7)\n  * Severe dehydration defined by a body weight loss of more than 10%\n  * Total food intolerance due to vomiting necessitating hospitalization\n  * Uncontrolled active hemorrhage\n* Significant ultrasound findings:\n\n  * Tubo-ovarian abscess ≥ 3 cm\n  * Significant intra-abdominal effusion\n* Non-French speaking patients\n* Inability to download or use the digital application due to precarious or isolated digital circumstances\n* Refusal to sign consent form\n* Patients under legal guardianship or court protection (tutelage, curatorship, or guardianship)\n* Patients not affiliated with a social security system","18 Years","60 Years",{"count":50,"type":20},200,[52],"NA","The GYNAB study aims to compare patient satisfaction and clinical outcomes between dematerialized post-emergency gynecological follow-up using a connected health app and traditional in-person follow-up. Conducted by Drs. Laëtitia CAMPIN and Louis MARCELLIN at Hôpital Cochin, it is sponsored by Assistance Publique - Hôpitaux de Paris. The main objective is to assess patient satisfaction at day 7 on a scale from 0 to 10, considering symptom management, follow-up quality, and task performance. Secondary objectives include comparing satisfaction at day 28, PROM-ED scores for symptom relief, understanding, reassurance, and care planning at days 7 and 28, hospitalization rates, unscheduled consultations, surgical interventions, total hospital time by day 28, and physician satisfaction at 28 days. This randomized trial involves women aged 18-60 needing follow-up for conditions like genital infections, non-complicated ectopic pregnancies, unlocated pregnancy, first trimester metrorrhagia, miscarriages , and severe vomiting before 12 weeks. Inclusion criteria are women aged 18-60 needing specified follow-up. Exclusion criteria are severe clinical intolerance, severe criteria ultrasound findings, non-French speakers, and inability to use digital applications. The intervention group uses a connected health app for data collection and communication, logging symptoms and test results, with medical team notifications for urgent updates. The control group receives traditional in-person follow-up with scheduled consultations and emergency contact information. The study hypothesizes that digital follow-up will improve patient experience, reduce hospital visits, and provide comparable or superior satisfaction and clinical outcomes. The results could promote broader digital health adoption in various medical fields.",[55,26,56,57,58],"Genital Diseases, Female","Uncertain Viability of Pregnancy","Abortion, Missed","Hyperemesis Gravidarum",[60,61,62,63,64,65,66],"Gynecological Emergencies","Post-Emergency Follow-Up","Patient-Reported Outcome Measures (PROMs)","Digital Health","Patient satisfaction","Telehealth","Asynchronous Medical Follow-up","RECRUITING","2026-04-20",{"date":70,"type":31},"2026-04-21",{"date":72,"type":31},"2025-06-30",{"date":74,"type":20},"2027-07-30",{"name":76,"class":38},"Assistance Publique - Hôpitaux de Paris",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":83,"enrollmentInfo":84,"targetDuration":86,"studyType":87,"phases":4,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":39},"100634611","doppler-flow-in-tubal-ectopic-pregnancy-in-diagnosis-as-a-predictor-of-treatment-success---conservative-and-mtx-treatment-100634611","NCT07541937","Doppler Flow in Tubal Ectopic Pregnancy in Diagnosis as a Predictor of Treatment Success - Conservative and MTX Treatment","Inclusion criteria:\n\n* Tubal ectopic pregnancy\n* Hemodynamically stable, with no suspicion of rupture,\n* Eligible for MTX or conservative therapy.\n\nExclusion criteria:\n\n* Intrauterine pregnancy\n* Hemodynamic instability\n* Suspected tubal rupture\n* Other ectopic pregnancy: CSP, Ovarian, heterotopic pregnancy","45 Years",{"count":85,"type":20},60,"2 Months","OBSERVATIONAL","The study \"Doppler Flow in Tubal Ectopic Pregnancy as a Predictor of Treatment Success: Conservative and MTX Therapy\" aims to evaluate the role of Doppler ultrasound parameters (RI, PI, and PSV) in predicting treatment success for tubal ectopic pregnancies. Ectopic pregnancies, affecting \\~2% of all pregnancies (98% in fallopian tubes), pose significant risks, including rupture and maternal mortality. Diagnosis is typically achieved via transvaginal ultrasound, with Doppler imaging enhancing accuracy by detecting characteristic vascular patterns.\n\nManagement options include conservative monitoring, methotrexate (MTX) therapy, or surgery, based on clinical stability, β-hCG levels, and ultrasound findings. While β-hCG levels are a known predictor of MTX treatment failure, there is no consensus on an optimal threshold. Prior research suggests increased vascularization on Doppler ultrasound may correlate with higher MTX success rates.\n\nThis prospective study will involve 60 women aged 18-45 with stable, unruptured tubal ectopic pregnancies. It will assess Doppler parameters and other clinical factors as predictors of treatment success. Findings aim to address gaps in the literature and improve management strategies for tubal ectopic pregnancies.",[26],[91,92,93],"ectopic pregnancy conservative management","Ectopic pregnancy MTX therapy","Doppler flow parameters in ectopic pregnancy","2026-04-14",{"date":70,"type":31},{"date":97,"type":31},"2024-06-01",{"date":99,"type":20},"2027-06-01",{"name":101,"class":38},"Meir Medical Center",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":114,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100626113","reproductive-health-education-birth-control-and-sexual-quality-of-life-in-ectopic-pregnancy-100626113","NCT07431411","Reproductive Health Education, Birth Control and Sexual Quality of Life in Ectopic Pregnancy","The Effect of Reproductive Health Education on Contraceptive Method Use Intention and Sexual Life Quality of Women Diagnosed With Ectopic Pregnancy","Inclusion Criteria:\n\n* Women admitted to the Obstetrics and Gynecology clinics at Izmir City Hospital,\n* Aged 18 years and older,\n* Diagnosed with ectopic pregnancy,\n* Able to read and write in Turkish,\n* Voluntarily agree to participate in the study.\n\nExclusion Criteria:\n\n* Women undergoing infertility treatment,\n* Women requesting tubal ligation.",{"count":110,"type":20},102,[52],"Ectopic pregnancy (EP) is defined as the implantation of a fertilized ovum outside the uterine cavity, most commonly in the fallopian tubes. EP is a potentially life-threatening condition due to the risk of tubal rupture and intra-abdominal bleeding. Management of ectopic pregnancy may involve medical or surgical treatment, often requiring hospitalization.\n\nFollowing treatment and discharge, women may experience physical, emotional, and sexual health challenges. In addition, the need for effective contraception after ectopic pregnancy treatment is critical due to the risk of recurrent ectopic pregnancy and the potential teratogenic effects of treatment agents such as methotrexate. However, limited data are available regarding contraceptive intentions and sexual quality of life after ectopic pregnancy treatment in Türkiye.\n\nThis study aims to evaluate contraceptive intention and sexual quality of life in women treated for ectopic pregnancy and to examine the relationship between length of hospital stay, contraceptive intention, and sexual quality of life. Data will be collected using the Participant Information Form, the Contraceptive Intention Scale (CIS), and the Sexual Life Quality Scale-Women (SLQS-W). In addition, a reproductive health educational brochure will be provided to participants as part of post-treatment counseling.",[26],[115,116,117,118],"ectopic pregnancy","reproductive health","quality of sexual life","health education","2026-02-23",{"date":121,"type":31},"2026-02-24",{"date":123,"type":20},"2026-02-18",{"date":125,"type":20},"2026-07-30",{"name":127,"class":38},"Buket Kömürcü",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":83,"enrollmentInfo":135,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":136,"conditions":137,"keywords":138,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":149},"100616521","posttraumatic-stress-disorder-in-ectopic-pregnancy-100616521","NCT07306689","Posttraumatic Stress Disorder in Ectopic Pregnancy","Posttraumatic Stress Disorder Symptoms Complicating Ectopic Pregnancy","Inclusion Criteria:\n\n* ectopic pregnancy\n* gestational age up to 14 weeks.\n\nExclusion Criteria:\n\n* heterotopic pregnancy",{"count":50,"type":20},"The objective of the study is to prospectively assess the prevalence of post-traumatic stress disorder (PTSD) symptoms in a population of women who have experienced a diagnosis of ectopic pregnancy. The investigation into the prevalence of PTSD symptoms will aid in better identifying women who may benefit from early psychological intervention.",[26],[115,139],"PTSD","2025-12-14",{"date":142,"type":31},"2025-12-29",{"date":144,"type":31},"2025-12-15",{"date":146,"type":20},"2027-12-31",{"name":148,"class":38},"Jagiellonian University",2,{"id":151,"slug":152,"hasResults":11,"nctId":153,"briefTitle":154,"officialTitle":155,"acronym":4,"eligibilityCriteria":156,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":157,"enrollmentInfo":158,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":160,"conditions":161,"keywords":162,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":39},"100607251","methotrexate-treatment-in-cases-of-ectopic-pregnancy-with-relative-contraindications-100607251","NCT07186127","Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications","A Retrospective Evaluation of the Effectiveness of Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications","Inclusion Criteria:\n\n* Diagnosed with ectopic pregnancy\n* Received methotrexate (MTX) treatment\n* Underwent surgical treatment due to lack of response to MTX therapy\n* Compliant with treatment follow-up\n\nExclusion Criteria:\n\n* Participants with contraindications to methotrexate (MTX) treatment\n* Participants non-compliant with follow-up","48 Years",{"count":159,"type":20},230,"Study Description (For Patients, Families, and Healthcare Providers)\n\nPurpose:\n\nThe aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for whom this treatment is relatively contraindicated.\n\nBackground:\n\nMethotrexate is a medication commonly used in the treatment of ectopic pregnancy (a pregnancy that occurs outside the uterus, usually in the fallopian tube). However, in certain conditions - such as kidney or liver dysfunction - methotrexate use may carry increased risks. These situations are known as relative contraindications. This study will retrospectively examine treatment outcomes in this specific patient population.\n\nMethod:\n\nThe study will analyze medical records of patients who were previously treated with methotrexate for ectopic pregnancy. No new interventions will be performed. The analysis will be based solely on existing clinical data.\n\nWhy Is This Important? The findings of this study may help us better understand the safety limits of methotrexate therapy and guide healthcare providers in managing similar cases in the future.",[26],[26,163,164,165],"Relative Contraindication","Methotrexate","Laparoscopic surgery","2025-09-15",{"date":168,"type":31},"2025-09-22",{"date":170,"type":31},"2025-05-01",{"date":172,"type":20},"2026-05-01",{"name":174,"class":175},"Bagcilar Training and Research Hospital","OTHER_GOV",{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":182,"eligibilityCriteria":183,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":184,"enrollmentInfo":185,"targetDuration":4,"studyType":21,"phases":187,"briefSummary":188,"conditions":189,"keywords":190,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":39},"100597332","comparison-of-vnotes-and-laparoscopic-salpingectomy-in-the-surgical-treatment-of-ectopic-pregnancy-100597332","NCT07057115","Comparison of vNOTES and Laparoscopic Salpingectomy in the Surgical Treatment of Ectopic Pregnancy","Comparison of vNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery) Salpingectomy and Laparoscopic Salpingectomy Performed for Ectopic Pregnancy","vNOTES","Inclusion Criteria:\n\nWomen diagnosed with ectopic pregnancy Without heterotopic pregnancy Women aged 18-55 years, within reproductive age Patients for whom medical treatment is not appropriate Patients requiring surgical intervention Patients without systemic diseases that may contraindicate surgery Patients who have signed and approved the informed consent form to participate in the study\n\nExclusion Criteria:\n\nEctopic pregnancy cases that can be treated with medical therapy Patients with advanced pelvic infections or pelvic anatomical abnormalities Patients with immunodeficiency or systemic diseases that contraindicate surgery","55 Years",{"count":186,"type":20},56,[52],"This study compares vNOTES salpingectomy and laparoscopic salpingectomy in the treatment of ectopic pregnancy, focusing on outcomes such as operative time, postoperative pain, and recovery.",[26],[182,191,192],"laparoscopy","salpingectomy","2025-08-03",{"date":195,"type":31},"2025-08-05",{"date":197,"type":31},"2025-07-01",{"date":199,"type":20},"2026-06-01",{"name":201,"class":175},"Gaziosmanpasa Research and Education Hospital",{"id":203,"slug":204,"hasResults":11,"nctId":205,"briefTitle":206,"officialTitle":207,"acronym":4,"eligibilityCriteria":208,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":4,"enrollmentInfo":209,"targetDuration":4,"studyType":21,"phases":211,"briefSummary":212,"conditions":213,"keywords":217,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":4},"100593697","nalbuphine-dosing-and-its-impact-on-anxiety-and-depression-in-ectopic-pregnancy-surgery-100593697","NCT07009808","Nalbuphine Dosing and Its Impact on Anxiety and Depression in Ectopic Pregnancy Surgery","Effects of Different Doses of Nalbuphine on Anxiety and Depression in Patients Undergoing Ectopic Pregnancy Surgery: A Prospective, Randomized, Controlled Study","Inclusion Criteria:\n\n1. Confirmed diagnosis of ectopic pregnancy, aged ≥18 years, and with normal psychological status.\n2. Patients planned to undergo single-port laparoscopic surgery under general anesthesia, followed by postoperative patient-controlled intravenous analgesia (PCIA).\n3. Patients classified as ASA I or II.\n4. Able to understand the study process and methods, voluntarily participate, and sign the informed consent form.\n\nExclusion Criteria:\n\n1. Patients using other analgesic methods or multiple analgesic approaches.\n2. Patients with a history of allergies or allergies to anesthetic drugs.\n3. Patients with a history of depression or mental illness.\n4. Patients with other severe organ dysfunction.\n5. Patients unable to operate the intravenous analgesia pump independently.",{"count":210,"type":20},165,[52],"This prospective, randomized, controlled study aims to evaluate the impact of different doses of nalbuphine on anxiety and depression in patients undergoing surgery for ectopic pregnancy. Ectopic pregnancy, which occurs in approximately 2% of all pregnancies, often requires surgical intervention, leading to potential psychological distress such as anxiety and depression in affected women. Effective postoperative pain management is essential to enhance recovery and reduce emotional disturbances.\n\nThe study will involve 165 eligible patients diagnosed with ectopic pregnancy at Jinjiang District Maternal and Child Health Hospital. Participants will be randomly assigned to three groups, each receiving a different concentration of nalbuphine combined with metoclopramide for postoperative analgesia. The primary outcome will focus on changes in anxiety and depression scores measured on postoperative day three, while secondary outcomes will assess pain levels, the use of patient-controlled analgesia (PCA), the necessity for rescue analgesics, and the occurrence of adverse reactions.\n\nSample size calculations suggest that at least 165 participants are required to achieve adequate statistical power. Data will be analyzed using SPSS 25.0 software, with results expected to provide insights into the effectiveness of nalbuphine in improving postoperative recovery and mental health in women experiencing ectopic pregnancy. The study has received ethical approval and is funded by the Chengdu Medical Research Projects (No. 2023465, 2022548, and 2023304).",[26,214,215,216],"Anxiety","Depression","Nalbuphine",[26,214,215,216],"2025-06-06",{"date":220,"type":31},"2025-06-08",{"date":222,"type":20},"2025-06-20",{"date":224,"type":20},"2025-10-30",{"name":226,"class":38},"Chengdu Jinjiang Maternity and Child Health Hospital",{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":232,"acronym":4,"eligibilityCriteria":233,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":83,"enrollmentInfo":234,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":236,"conditions":237,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":4},"100571526","psychatric-effect-of-ectopic-pregnancy-100571526","NCT06721403","Psychatric Effect of Ectopic Pregnancy","Assessment of Anxiety,Depressive Symptoms &PTSD in Cases of Post Ectopic Pregnancy","Inclusion Criteria:\n\n* All pregnant woman 18:45 years old presented with ectopic pregnancy.\n\nExclusion Criteria:\n\n* intrauterine pregnancy\n* previous diagnosis of psychiatric disorders\n* Unwell to give consent",{"count":235,"type":20},85,"Assessment of anxiety,depressive symptoms and post traumatic stress after ectopic pregnancy Determine factors associated with development of anxiety,depressive symptoms and post-traumatic stress after ectopic pregnancy",[26],"2024-12-05",{"date":240,"type":31},"2024-12-06",{"date":242,"type":20},"2025-01-01",{"date":244,"type":20},"2026-04-30",{"name":246,"class":38},"Assiut University",{"id":248,"slug":249,"hasResults":11,"nctId":250,"briefTitle":251,"officialTitle":252,"acronym":4,"eligibilityCriteria":253,"healthyVolunteers":254,"sex":15,"minAge":47,"maxAge":255,"enrollmentInfo":256,"targetDuration":4,"studyType":21,"phases":258,"briefSummary":259,"conditions":260,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":268,"locationsCount":4},"100558733","chromotubation-on-the-remaining-fallopian-tube-after-a-laparoscopic-salpingectomy-due-to-tubal-pregnancy-100558733","NCT06554964","Chromotubation on the Remaining Fallopian Tube After a Laparoscopic Salpingectomy Due to Tubal Pregnancy","Feasibility, Safety and Effectiveness of Chromotubation on the Remaining Fallopian Tube After a Laparoscopic Salpingectomy Due to Tubal Pregnancy","Inclusion Criteria:\n\nPatients undergoing laparoscopic salpingectomy for tubal ectopic pregnancy.\n\nExclusion Criteria:\n\n1. Patients with a history of unilateral salpingectomy\n2. Patients with suspected heterotopic pregnancy\n3. Patients with suspected allergic reaction to blue dye injection",true,"50 Years",{"count":257,"type":20},100,[52],"Ectopic pregnancy prevalence is approximately 1-2% of all pregnancies, majority of which located in the fallopian tube. Among the risk factors for ectopic pregnancy is tubal factor - meaning a mechanical problem within the fallopian tube resulting in the pregnancy remaining in the fallopian tube. The treatment o tubal pregnancy can be expectant, medical via metotrexate or surgicl via laparoscopic salpingectomy of the involved fallopian tube. The purpose of this study is to assess the feasibility of chromotubation during laparoscopic salpingectomy for the surgical management of tubal ectopic pregnancy hence assessing the function of the remaining fallopian tube and trying to predict future fertility for the patient.",[26],"2024-10-03",{"date":263,"type":31},"2024-10-08",{"date":265,"type":20},"2024-09-30",{"date":267,"type":20},"2025-09-01",{"name":269,"class":175},"Assaf-Harofeh Medical Center",{"id":271,"slug":272,"hasResults":11,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":4,"eligibilityCriteria":276,"healthyVolunteers":254,"sex":15,"minAge":47,"maxAge":83,"enrollmentInfo":277,"targetDuration":4,"studyType":21,"phases":279,"briefSummary":280,"conditions":281,"keywords":284,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":286,"lastUpdatePostDateStruct":287,"startDateStruct":289,"completionDateStruct":290,"leadSponsor":292,"locationsCount":4},"100553463","novel-diagnosis-of-ectopic-pregnancy-100553463","NCT06486415","Novel Diagnosis of Ectopic Pregnancy","Serial Measurement of Beta-Human Chorionic Gonadotropin (BHCG) Values During the Day in the Diagnosis of Ectopic Pregnancy","Inclusion Criteria:\n\n* Positive bhcg levels\n\nExclusion Criteria:\n\n* clinically diagnosis of intrauterine pregnancy",{"count":278,"type":20},20,[52],"In the project, the investigators aim to determine the Beta- human chorionic gonadotropin (BHCG) value with serial measurements on the same day in the diagnosis of ectopic pregnancy.",[26,282,283],"hCG","Pregnancy of Unknown Location",[115,282,285],"Pregnancy with unknown location","2024-07-01",{"date":288,"type":31},"2024-07-03",{"date":286,"type":20},{"date":291,"type":20},"2025-04-01",{"name":293,"class":38},"Acibadem University",{"id":295,"slug":296,"hasResults":11,"nctId":297,"briefTitle":298,"officialTitle":298,"acronym":4,"eligibilityCriteria":299,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":300,"enrollmentInfo":301,"targetDuration":4,"studyType":87,"phases":4,"briefSummary":303,"conditions":304,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":305,"lastUpdatePostDateStruct":306,"startDateStruct":308,"completionDateStruct":310,"leadSponsor":312,"locationsCount":39},"100552290","the-effect-of-different-treatment-modalities-of-tubal-ectopic-pregnancy-on-ovarian-reserve-a-prospective-cohort-study-100552290","NCT06471166","The Effect of Different Treatment Modalities of Tubal Ectopic Pregnancy on Ovarian Reserve: a Prospective Cohort Study","Inclusion Criteria:\n\n* The study will include patients aged 18-44 years with known diagnosis or suspicion of diagnosis of tubal ectopic pregnancy (abnormal doubling rates of their b-HCG levels as well as ultrasonographically identified or unidentified gestational sacs outside the uterus)\n* Included patients must have capacity to provide informed consent. Given the potential emergent nature of presentation, women will not be recruited if fully informed consent could be compromised due to a highly distressed emotional state or significant hemorrhage necessitating the need for urgent surgery\n\nExclusion Criteria:\n\n1. The use of hormonal contraceptives within two months of enrolment\n2. If other surgery was conducted at the time of salpingectomy.\n3. If a woman was pregnant at follow up visit for AMH measurement\n4. History of previous surgeries of fallopian tubes and\u002For ovaries","44 Years",{"count":302,"type":20},90,"Detect the effect of different treatment modalities of tubal ectopic pregnancy on ovarian reserve",[26],"2024-06-18",{"date":307,"type":31},"2024-06-24",{"date":309,"type":20},"2024-07-10",{"date":311,"type":20},"2025-10-10",{"name":246,"class":38},{"id":314,"slug":315,"hasResults":11,"nctId":316,"briefTitle":317,"officialTitle":318,"acronym":319,"eligibilityCriteria":320,"healthyVolunteers":11,"sex":15,"minAge":47,"maxAge":4,"enrollmentInfo":321,"targetDuration":4,"studyType":21,"phases":323,"briefSummary":325,"conditions":326,"keywords":327,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":330,"lastUpdatePostDateStruct":331,"startDateStruct":333,"completionDateStruct":335,"leadSponsor":337,"locationsCount":39},"100543328","phase-4-use-of-letrozole-for-ectopic-pregnancy-100543328","NCT06354439","Use of Letrozole for Ectopic Pregnancy","Use of Letrozole in the Treatment of Early Ectopic Pregnancy","EcZOL","Inclusion Criteria:\n\n* 18 years or older\n* Diagnosis of ectopic pregnancy\n* Desire for reproduction\n* Ease of return\n* Undetermined pregnancy location with abnormal hCG growth\n* Presence of a heterogeneous adnexal mass on pelvic ultrasound suggestive of a tubal ectopic pregnancy with an hCG level ≤ 3000 mIU\u002Fml\n* Absence of fetal cardiac activity\n* Average diameter of the adnexal mass ≤ 3.5 cm\n* Hemodynamically stable\n* No significant abdominal pain (i.e, \\\u003C 6 on a visual analog scale)\n\nExclusion Criteria:\n\n* Presence of a significant amount of free fluid in the pelvis (as assessed by the ultrasound technician)\n* Allergy to methotrexate or letrozole\n* A reduction in β-hCG ≥ 50% in 2 measurements with 48 hours between them or\n\n  ≥ 85% in 4 days, or ≥ 95% in 7 days before randomization\n* Abnormal liver function test (Alanine transaminase (ALT) ≥ 2 times the upper limit of normal)\n* Abnormal renal function test (glomerular filtration rate ≤ 45 ml\u002Fmin)\n* Hemoglobin \\\u003C10 g\u002Fdl\n* Platelets \\\u003C120.000\u002Fml\n* Presence of heterotopic pregnancy\n* Do not wish to participate in the study.",{"count":322,"type":20},130,[324],"PHASE4","A randomized clinical trial using oral letrozole 10mg\u002Fday for 7 days, for treating early cases of ectopic pregnancy, compared to intramuscular methotrexate",[26],[115,328,329],"letrozole","methotrexate","2024-04-05",{"date":332,"type":31},"2024-04-09",{"date":334,"type":31},"2024-03-27",{"date":336,"type":20},"2026-12-31",{"name":338,"class":38},"Hospital de Clinicas de Porto Alegre"]