[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"edentulous-jaw\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:edentulous-jaw":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,39,65,90,127,155,180,201],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100642732","accuracy-of-complete-arch-implant-photogrammetry-100642732",false,"NCT07643441","Accuracy of Complete-Arch Implant Photogrammetry","Accuracy of Complete-arch Implant Scans Obtained Using Intraoral Photogrammetry and a Mobile-phone Based Photogrammetry.","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Completely edentulous patients rehabilitated with implant-supported complete-arch prostheses.\n* Presence of at least four osseointegrated implants in the edentulous arch.\n* Patients able to undergo digital implant scanning procedures.\n* Patients willing to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Patients with unstable or failed implants.\n* Presence of peri-implant disease, active oral infection, or significant soft-tissue inflammation around the implants.\n* Inadequate access for placement of photogrammetry scan bodies or markers.\n* Patients with conditions that prevent proper scanning procedures (e.g., inability to maintain mouth opening or remain still during data acquisition).\n* Patients requiring immediate implant placement or immediate loading protocols.\n* Patients unwilling or unable to provide informed consent.\n* Incomplete clinical records or inability to complete all study procedures.","ALL","18 Years","50 Years",{"count":20,"type":21},42,"ESTIMATED","OBSERVATIONAL","This prospective comparative clinical study evaluated the accuracy and chairside time of complete-arch implant scans obtained using an intraoral photogrammetry system and a mobile-phone-based photogrammetry system in edentulous patients rehabilitated with complete-arch implant-supported prostheses. Implant positions recorded by each system were compared with a reference dataset to assess linear and angular discrepancies. The chairside time required for data acquisition was also measured. The study aimed to determine whether mobile-phone-based photogrammetry can provide clinically acceptable accuracy comparable to that of intraoral photogrammetry while improving clinical efficiency. The findings may help clinicians select appropriate digital impression techniques for complete-arch implant rehabilitation.",[25],"Edentulous Jaw","RECRUITING","2026-06-07",{"date":29,"type":30},"2026-06-11","ACTUAL",{"date":32,"type":30},"2026-01-01",{"date":34,"type":21},"2026-08-01",{"name":36,"class":37},"Menoufia University","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":46,"targetDuration":4,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":54,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":38},"100642830","clinical-outcomes-of-3d-printed-and-milled-complete-dentures-100642830","NCT07586774","Clinical Outcomes of 3D Printed and Milled Complete Dentures","An Open, Single-center, Prospective, Randomized, Two-armed, Interventional, Post-market Clinical Investigation of 3D Printed Complete Dentures and Milled Complete Dentures During a 5-year Follow-up Period","Inclusion Criteria:\n\n* Adult aged 18 years or above at time of informed consent.\n* Subject willing to participate in the clinical investigation and able to understand the content of the clinical investigation.\n* Subject willing to comply with investigational related procedures and to return for follow-up visits for a period of 5 years.\n* Subject has signed and dated the informed consent form.\n* Subjects in need of complete dentures in maxilla and mandible.\n* Prosthodontic Diagnostic Index (PDI) Completely edentulous classification (Class 1-3).\n* History of edentulism of at least 1 year.\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to any of the components.\n* Subjects with significant systemic health issues or chronic conditions (American Society of Anesthesiologists (ASA) class 3-6 ).\n* Known pregnancy at time of enrolment.\n* Subjects unlikely to comply with investigational procedures, or unlikely to come back for follow-up visits, as judged by the Investigator.\n* Previous enrolment in the present clinical investigation.\n* Involvement in the planning and conduct of the clinical investigation (applies to both Dentsply Sirona personnel and the clinical investigation site).\n* PDI Completely edentulous classification (Class 4)\n\n  * Presence of severely atrophied ridge.\n  * Presence of severe ridge undercuts.\n  * Clinically severe Xerostomia.\n  * Absence of hard or soft tissue pathology that precludes denture therapy.\n  * Maxillofacial defects.\n* Uncontrolled pathological process in the oral cavity, as judged by the Investigator.\n* Participation in another clinical investigation that may interfere with the present clinical investigation.",{"count":47,"type":21},68,"INTERVENTIONAL",[50],"NA","This is a two-armed, single-center clinical study evaluating performance, efficacy and safety of three dimensional (3D) printed complete dentures and milled complete dentures during a 5-year follow-up period. The primary objective of this clinical investigation is to evaluate survival rate, i.e. subjects with survived dentures in both upper and lower jaw, of 3D printed complete dentures and milled complete dentures after 1 year (in each of the groups separately).",[53,25],"Edentulous Mouth","NOT_YET_RECRUITING","2026-06-05",{"date":57,"type":30},"2026-06-08",{"date":59,"type":21},"2026-05-30",{"date":61,"type":21},"2032-10-30",{"name":63,"class":64},"Dentsply Sirona Implants and Consumables","INDUSTRY",{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":4,"eligibilityCriteria":71,"healthyVolunteers":72,"sex":16,"minAge":17,"maxAge":73,"enrollmentInfo":74,"targetDuration":4,"studyType":48,"phases":76,"briefSummary":77,"conditions":78,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":38},"100606589","primary-stability-and-peri-implant-outcomes-of-short-implants-in-post-extraction-single-tooth-sites-100606589","NCT07177521","Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites","Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites: a Randomized Controlled Trial.","Inclusion Criteria:\n\n* Age ≥18 years.\n* Single-tooth post-extraction sites requiring immediate implant placement in posterior regions (premolars\u002Fmolars) or selected anterior sites.\n* Planned short implant (≤7-8 mm length, 3.5-5.0 mm diameter).\n* Adequate oral hygiene, no active periodontal disease.\n* Written informed consent.\n\nExclusion Criteria:\n\n* Heavy smoking (\\>20 cigarettes\u002Fday).\n\n  * Uncontrolled diabetes or systemic conditions affecting bone healing.\n  * Current bisphosphonate\u002Fantiresorptive therapy.\n  * Immunosuppression, pregnancy.\n  * Poor oral hygiene or acute infection at site.\n  * Severe bone dehiscence preventing primary stability.",true,"75 Years",{"count":75,"type":21},10,[50],"The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time. The management of the peri-implant gap and soft tissues may influence primary stability, hard\u002Fsoft tissue remodeling, and implant success.",[25,79,80],"Tooth Loss","Toothless Mouth","2026-01-23",{"date":83,"type":30},"2026-01-27",{"date":85,"type":30},"2025-01-10",{"date":87,"type":21},"2026-08-10",{"name":89,"class":37},"University of Bari Aldo Moro",{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":96,"eligibilityCriteria":97,"healthyVolunteers":72,"sex":16,"minAge":98,"maxAge":99,"enrollmentInfo":100,"targetDuration":4,"studyType":48,"phases":102,"briefSummary":103,"conditions":104,"keywords":108,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":38},"100597976","accuracy-of-standard-and-geometric-pattern-assisted-digital-scanning-for-full-arch-implant-prosthesis-frameworks-100597976","NCT07065487","Accuracy of Standard and Geometric Pattern-Assisted Digital Scanning for Full-Arch Implant Prosthesis Frameworks","Accuracy of Standard vs Geometric Pattern-Assisted Digital Scanning Techniques for Construction of Full Arch Implant Prosthesis Framework: A Crossover Study","GPA Scan","Inclusion Criteria:\n\nAdults aged 30 to 70 years\n\nCompletely edentulous mandible\n\nPresence of four osseointegrated implants in the lower jaw\n\nGood oral and general health\n\nWillingness to participate and provide written informed consent\n\nAvailability for all study appointments\n\nExclusion Criteria:\n\nSystemic diseases or conditions that affect bone healing or implant integration\n\nPresence of oral inflammation, infection, or soft tissue abnormalities at implant sites\n\nHistory of bruxism or parafunctional habits\n\nInability to understand or comply with study procedures","30 Years","70 Years",{"count":101,"type":21},4,[50],"This clinical trial aims to compare three different impression techniques used to fabricate full-arch implant-supported dental prostheses. Accurate impressions are essential to ensure a passive and precise fit of the final prosthetic framework, which contributes to long-term implant success and patient comfort.\n\nIn this crossover study, participants with four osseointegrated dental implants in the lower jaw will undergo three types of impressions:\n\nConventional splinted impression using polyvinyl siloxane (PVS) material.\n\nStandard digital impression using an intraoral scanner.\n\nGeometric pattern-assisted digital impression, which incorporates a visual reference pattern to improve scan alignment and accuracy.\n\nEach participant will receive all three impression techniques in a randomized sequence, at different time points. The accuracy of each method will be assessed by evaluating the passivity of the resulting prosthetic frameworks using two methods: (1) digital superimposition analysis to measure three-dimensional (3D) spatial deviation, and (2) the clinical \"one-screw test\" to detect misfit.\n\nThe study seeks to determine whether digital scanning, particularly with geometric pattern assistance, can provide accuracy comparable to or better than conventional methods. Findings may guide improvements in digital prosthodontic workflows and support more efficient, predictable treatment outcomes.",[25,105,106,107],"Dental Prosthesis, Implant-Supported","Prosthodontics","Dental Implantation, Endosseous",[109,110,111,112,113,114,115,116,117],"Digital impression","Full-arch implant","Geometric pattern","Prosthesis framework","Intraoral scanner","Splinted impression","CAD\u002FCAM prosthodontics","Passive fit","Dental implants","2025-07-13",{"date":120,"type":30},"2025-07-15",{"date":122,"type":21},"2025-09-30",{"date":124,"type":21},"2026-09-15",{"name":126,"class":37},"Mirna ashraf anis heneen",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":72,"sex":16,"minAge":134,"maxAge":4,"enrollmentInfo":135,"targetDuration":4,"studyType":48,"phases":137,"briefSummary":138,"conditions":139,"keywords":140,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":154},"100510280","marginal-bone-changes-in-fixed-all-on-four-mandibular-prosthesis-using-ot-bridge-attachment-system-100510280","NCT05924386","Marginal Bone Changes in Fixed All-on-Four Mandibular Prosthesis Using OT Bridge Attachment System","Marginal Bone Changes in Fixed All-on-Four Mandibular Prosthesis Using OT Bridge Attachment System Versus Conventionally Screw Retained Multiunit Abutments: A Randomized Clinical Trial","Inclusion Criteria:\n\nPatients with completely edentulous patients\n\n* Aged 40 years or older.\n* Sufficient inter -arch space not less than 13 mm.\n* Good oral hygiene\n* Minimum bone height 10 mm and minimum bone diameter should be 6 mm\n\nExclusion Criteria:\n\n* General contraindications for oral surgery\n* Heavy smokers (greater than 20 cigarettes a\n* Local acute or chronic infections\n* Substance abuse (drugs or alcohol)\n* Patients with neuromuscular or psychiatric disorders.\n* Treatment with intravenous bisphosphonates\n* Irradiation of the neck or head area in the past 5 years\n* Diabetic patients (HbA1c\\>7.5%)","40 Years",{"count":136,"type":21},20,[50],"Group I (control) Edentulous mandible receiving all on four fixed mandibular prosthesis using conventionally screw retained multiunit abutments.\n\nGroup II (intervention) Edentulous mandible receiving all on four fixed prostheses using OT bridge attachments system.\n\nFor both groups, the implant sites will be prepared aided by the surgical template. 4 implants with length 11-13 mm will be placed, two anterior implants will be aligned in an axial orientation and two posterior implants will be distally aligned according to the all-on-four concept in the inter foraminal area. Implants will be ideally placed at bone level.\n\nFor both groups:\n\nAfter implant placement and surgical guide removal, healing abutments ( will be connected during healing periods (eight to twelve weeks).\n\nGroup I ( control) After eight to twelve weeks from implant placement, multiunit abutments with appropriate heights and angulations will be connected to the implants.\n\nGroup II ( intervention) After eight to twelve weeks from implant placement, narrow- and low-profile OT Equator abutment will be screwed onto the implants according to the manufacturer.\n\nmarginal bone changes and prosthetic complications are the outcomes Radiographic follow up will be performed for marginal bone changes Serial of standardized digital periapical radiographs using will be taken at the time fixed prosthesis insertion (baseline), 3,6,9,12 months.\n\nType and incidence of prosthetic complications for the prothesis for each group will be evaluated in 3, 6,9 and 12 months, these complications included: loosening or fracture of the prosthetic screw, prosthesis mobility and fracture of the prosthesis.",[25],[141,142,143,144],"OTbridge attachment","ALL ON 4","fixed supported implant prosthesis","conventional screw retained fixed prosthesis","2025-04-23",{"date":147,"type":30},"2025-04-25",{"date":149,"type":30},"2024-12-01",{"date":151,"type":21},"2026-01-31",{"name":153,"class":37},"Cairo University",2,{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":72,"sex":16,"minAge":18,"maxAge":162,"enrollmentInfo":163,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":165,"conditions":166,"keywords":167,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":38},"100522285","facial-prediction-technology-for-edentulous-patients-100522285","NCT06080633","Facial Prediction Technology for Edentulous Patients","Research on Facial Prediction Technology for Edentulous Implant-Supported Fixed Prostheses Based on Multimodal Data Fusion","Inclusion Criteria:\n\n* Patients with complete edentulism,\n* aged 50 years or above,\n* in good physical health,\n\nExclusion Criteria:\n\n* patients who refuse to participate in the study，\n* patients who cannot undergo facial scanning.","100 Years",{"count":164,"type":21},24,"According to data from the World Health Organization, approximately 160 million people worldwide are edentulous. The incidence increases with age, and the proportion of edentulous patients is higher in the population aged 60 and above. Loss of teeth or edentulism can affect facial appearance, causing people to feel self-conscious and loss confidence in social situations, and even lead to psychological illnesses. Therefore, edentulous patients not only pay close attention to the recovery of oral function but also attach great importance to facial contour improvement. For a long time, due to technological limitations, clinicians have been unable to depict the changes in facial contour after implant placement for patients before surgery. However, with the development of artificial intelligence technology, deep learning-based methods for predicting soft tissue facial deformation have made this mission a possibility. This study established a multi-modal dataset for edentulous patients before and after implant restoration to lay the foundation for predicting facial contour changes after implant treatment. A graph generative adversarial network based on multi-modal data was proposed to achieve fast and high-precision facial contour prediction. To address the common challenges of slow computation and excessive computational resource consumption in current triangular mesh deformation simulation methods, this project innovatively proposed a graph generative adversarial network that uses multi-modal data and incorporates self-attention mechanisms to achieve fast and high-precision facial contour prediction for edentulous patients after implant restoration.",[25],[25,168,169,170],"deep learning","oral implantology","facial prediction","2024-06-12",{"date":173,"type":30},"2024-06-13",{"date":175,"type":30},"2023-06-01",{"date":177,"type":21},"2026-12-01",{"name":179,"class":37},"KU Leuven",{"id":181,"slug":182,"hasResults":11,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":4,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":187,"targetDuration":4,"studyType":48,"phases":189,"briefSummary":190,"conditions":191,"keywords":4,"overallStatus":54,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":38},"100527797","maxillary-implant-overdentures-retained-by-bars-or-locator-100527797","NCT06152432","Maxillary Implant Overdentures Retained by Bars or Locator","Maxillary Implant Overdentures Retained by Bars or Locator Attachments: a 10-year Comparative Prospective Study.","Inclusion Criteria:\n\n* Fully edentulous patients or patients with an overdenture in the mandible, who were referred to the Department of Oral and Maxillofacial Surgery (University Medical Center Groningen, the Netherlands) 10 years ago, because they suffered from a lack of retention and stability of the upper (and lower) denture;\n* Edentulous in the maxilla for at least one year;\n* Sufficient bone volume in height in the anterior region of the maxilla to place the implants;\n* The patient was 18 years or older;\n* Sufficient interocclusal space for placement of an overdenture with attachment system;\n* The patient was capable of understanding and giving informed consent.\n\nExclusion Criteria:\n\nExclusion criteria at the time of treatment:\n\n* Patients with American Society of Anesthesiologists score (ASA score) ≥ III;\n* Patients who were smoking;\n* Patients with a history of radiotherapy in the head and neck region;\n* Patients with a history of pre-prosthetic surgery or previous implant placement in the maxilla.",{"count":188,"type":21},50,[50],"* Background Patients experiencing problems with their conventional maxillary denture can benefit from implant- retained overdentures. Several retention systems are available. These retention systems can be roughly divided into bar-retained implant overdentures, in which multiple implants are splinted and the overdenture is attached through retentive clips, and into retention systems using non-splinted solitary attachments (locators). Evidence on maxillary implant overdenture attachment systems has been mostly short to medium term, non-comparing or retrospective. Even more, 10-years data of comparative studies are lacking.\n* Main research question To compare treatment outcomes of fully edentulous patients with maxillary overdentures, supported by four implants, retained by either bars or locators . The primary objective of the study is to analyze marginal bone level changes by radiological assessments at 10-years follow-up. Secondary objectives are implant and overdenture survival, condition of peri- implant mucosa and patients' satisfaction.\n* Design (including population, confounders\u002Foutcomes) The study design is an observational study of a group of patients which were treated 10 years ago with dental implants and an overdenture in the maxilla because of problems with retention and stability with their conventional denture. Outcomes: primary outcome is the change in marginal peri-implant bone level 10 years after placing the overdenture. Secondary outcome measures will be implant and overdenture survival, peri-implant mucosa health and patients' satisfaction using a questionnaire.",[25],"2024-05-08",{"date":194,"type":30},"2024-05-09",{"date":196,"type":21},"2024-10-01",{"date":198,"type":21},"2027-12-31",{"name":200,"class":37},"University Medical Center Groningen",{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":4,"eligibilityCriteria":207,"healthyVolunteers":72,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":208,"targetDuration":4,"studyType":48,"phases":210,"briefSummary":211,"conditions":212,"keywords":215,"overallStatus":54,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":4},"100537352","rct-comparing-ks-versus-ts-for-ovedenture-100537352","NCT06276712","RCT Comparing KS Versus TS for Ovedenture","A Randomized Controlled Trial Comparing Titanium Grade V (KS) Versus Titanium Grade IV (TS) Implants for the Treatment of Edentulous Mandible","Inclusion Criteria:\n\n* Any edentulous patient (post-extractive sites must to be healed from at least 3 months), with sufficient bone height and width in the anterior mandible (between canines) to allow the placement of two implants of 3.5 mm diameter of at least 8.5 mm of length.\n* 18 years or older, and able to sign an informed consent.\n* Smokers will be included and categorized into: 1) non smokers; 2) moderate smokers (smoking up to 10 cigarettes\u002Fday); 3) heavy smokers (smoking more than 11 cigarettes\u002Fday).\n* In case of post-extractive sites, they must have been healing for at least 3 months before being treated in the study.\n\nExclusion Criteria:\n\nExclusion criteria\n\n* General contraindications to implant surgery.\n* Patients irradiated in the head and neck area.\n* Immunosuppressed or immunocompromised patients.\n* Patients treated or under treatment with intravenous amino-bisphosphonates.\n* Patients with untreated periodontitis.\n* Patients with poor oral hygiene and motivation.\n* Previous guided bone reconstruction at the intended implant sites.\n* Uncontrolled diabetes.\n* Pregnancy or nursing.\n* Substance abuser.\n* Psychiatric problems or unrealistic expectations.\n* Lack of opposite occluding dentition in the area intended for implant placement.\n* Patients with infection and or inflammation in the area intended for implant placement.\n* Patients participating in other studies, if the present protocol cannot be properly adhered to.\n* Patients referred only for implant placement and cannot be followed ant the treating centre.\n* Patients unable to be followed for 5 years.",{"count":209,"type":21},48,[50],"To evaluate the clinical and radiographic outcomes of KS implants used to rehabilitate edentulous mandible with dental-retained overdentures, and to compare it with same treatment on TS implants",[213,214,25],"Dental Implant","Dental Implant-Abutment Design",[213,216,217],"Overdenture","Implant-abutment connection","2024-02-21",{"date":220,"type":30},"2024-02-26",{"date":222,"type":21},"2024-03-01",{"date":224,"type":21},"2028-01-30",{"name":226,"class":37},"Università degli Studi di Sassari"]