[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ehlers-danlos-syndrome-eds\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ehlers-danlos-syndrome-eds":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100628626","stable-pilates-for-hypermobility-100628626",false,"NCT07464093","STABLE Pilates for Hypermobility","Pilates for Hypermobility: A Pilot Feasibility Study","STABLE","Inclusion Criteria:\n\n* ≥ 18 years old;\n* Self-reported hypermobility with confirmed or suspected diagnosis of hEDS\u002FHSD;\n* Self-reported persistent pain ≥ 3 months;\n* A minimum of 3\u002F10 self-reported pain intensity in the past week\n* Able to get on and off the floor without assistance;\n* Able to communicate fluently in English; and\n* Able to provide written, informed consent\n\nExclusion Criteria:\n\n* Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min\u002Fweek over the past 6 months;\n* Recent surgery or acute bone, joint or nerve injury (\\\u003C6 months);\n* Have a history of a severe or progressive neurological or movement disorder;\n* Pregnant, planning to become pregnant during the study, or currently breast feeding;\n* Unable to get on and off the floor without assistance;\n* Unable to complete study procedures due to cognitive impairment;\n* Unable to provide written, informed consent; or\n* Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.",[27,28,29],"Ehlers-Danlos Syndrome (EDS)","Hypermobile EDS (hEDS)","Hypermobile Spectrum Disorder",[31,32,33],"hypermobility","pilates","pain","RECRUITING","2026-06-09",{"date":37,"type":38},"2026-06-11","ACTUAL",{"date":40,"type":21},"2026-07",{"date":42,"type":21},"2027-12",{"name":44,"class":45},"Brigham and Women's Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":46},"100604573","impact-of-ehlers-danlos-syndrome-on-gynaecological-health-100604573","NCT07151274","Impact of Ehlers-Danlos Syndrome on Gynaecological Health","Impact of Ehlers-Danlos Syndrome on Gynaecological Health: Focus on the Prevalence of Dysmenorrhoea","GYNESED","Inclusion Criteria:\n\n* Women aged 18 or over.\n* Willing to participate voluntarily in the study via an online questionnaire.\n* Of childbearing age.\n* Reporting a diagnosis of EDS (all types) or not having EDS (control group) and being part of a database of healthy volunteers.\n\nExclusion Criteria:\n\n* Minors (\\\u003C 18 years old).\n* Menopausal women\n* People who do not understand French well enough to complete the questionnaire.\n* Uncertain diagnosis of EDS (exclusion of participants who suspect EDS but without medical confirmation).",true,"FEMALE","50 Years",{"count":59,"type":21},156,"OBSERVATIONAL","Dysmenorrhea is a common problem in gynaecology, significantly impacting patients' quality of life. Ehlers-Danlos syndrome (EDS) is associated with joint hypermobility, tissue fragility and chronic pain. Some studies suggest an increased prevalence of gynaecological disorders, including dysmenorrhea, in patients with EDS. However, data remain limited and few studies have compared the intensity and characteristics of dysmenorrhea in women with EDS. There is also little data on the prevalence of other gynaecological conditions in women with EDS.\n\nThis study therefore aims to compare the severity of dysmenorrhea in patients with EDS and a control group in order to better characterise the gynaecological impact of EDS. It will also compare the prevalence of other gynaecological conditions between women with EDS and women without EDS.",[27],[64,65,66,67,68],"gynaecological disorder","dysmenorrhea","menorrhagia","dyspareunia","endometriosis","2026-06-08",{"date":71,"type":38},"2026-06-10",{"date":73,"type":38},"2025-07-07",{"date":75,"type":21},"2026-08-01",{"name":77,"class":45},"University Hospital, Rouen",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":4},"100605986","multicentre-longitudinal-study-of-bone-mineralisation-characteristics-in-marfan-syndrome-and-ehlers-danlos-syndrome-100605986","NCT07169669","Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos Syndrome","BONE","Inclusion Criteria:\n\n* Subjects with Marfan syndrome and Ehlers-Danlos syndrome according to the revised reference criteria belonging to the Cardiovascular genetic center at IRCCS Policlinico San Donato and the Reference Centre for Ehlers-Danlos Syndromes Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico;\n* Adult and paediatric subjects who have performed at least one Bone Mineral Densitometry within the observation period of the study.\n\nExclusion Criteria:\n\n* Presence of prostheses in the spinal column;\n* Presence of prostheses in the coxofemoral joint;\n* Oncological bone diseases reported in history.",{"count":86,"type":21},150,"The general objective of this research is to evaluate the characteristics of bone mineralisation in patients with Marfan syndrome or Ehlers-Danlos syndrome on a large case series.\n\nIn particular we intend to obtain data regarding the characteristics of bone mineralisation, as well as their variation over time and the relationships existing with other clinical-anamnestic parameters, in patients with Marfan syndrome or Ehlers-Danlos syndrome by retrospectively analysing (data already collected for normal clinical practice and already available at the hospital) the case history of the Cardiovascular genetic center at IRCCS Policlinico San Donato and the related Computerized Bone Mineralometry (MOC) examinations performed at the Radiology Service of the same hospital between 1 September 2019 and 31 December 2022.",[89,27,90],"Marfan Syndrome","Mineral Density","NOT_YET_RECRUITING","2025-09-04",{"date":94,"type":38},"2025-09-12",{"date":96,"type":21},"2025-10-31",{"date":98,"type":21},"2026-05-31",{"name":100,"class":45},"IRCCS Policlinico S. Donato"]