[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"electrical-stimulation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:electrical-stimulation":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100638363","photobiomodulation-effects-on-fatigue-and-muscle-damage-induced-by-nmes-100638363",false,"NCT07602933","Photobiomodulation Effects on Fatigue and Muscle Damage Induced by NMES","Effects of Photobiomodulation on Fatigue and Muscle Damage Induced by Neuromuscular Electrical Stimulation in Healthy Individuals: a Randomized Clinical Trial","Inclusion Criteria:\n\n* Healthy male and female volunteers.\n* Age between 18 and 45 years.\n* Practice physical activity regularly\n* No history of musculoskeletal injuries in the lower limbs in the last 6 months\n* Ability to tolerate NMES\n\nExclusion Criteria:\n\n* Have sensory intolerable changes due to NMES\n* Consumed coffee or another stimulant in the last 12 hours\n* Have a body mass index (BMI) greater than 30 kg\u002Fm2 (grade I obesity)\n* Present any contraindication for the performance of maximum effort\n* Abnormal increase in blood pressure after maximal exertion",true,"ALL","18 Years","45 Years",{"count":21,"type":22},36,"ESTIMATED","INTERVENTIONAL",[25],"NA","Neuromuscular electrical stimulation (NMES) is widely used to improve muscle strength and mitigate atrophy. However, its clinical efficacy is often limited by early neuromuscular fatigue, muscle damage, and discomfort, which reduce patient tolerance and contraction time. Photobiomodulation (PBM) has emerged as a potential therapy to enhance muscle performance and accelerate recovery by minimizing fatigue and damage. Despite its potential, few studies have investigated the effects of PBM applied specifically before an NMES-evoked fatigue protocol. This randomized, double-blind, placebo-controlled trial aims to evaluate the acute effects of PBM on neuromuscular fatigue, muscle damage, and functional outcomes in healthy young subjects. Participants will receive either active PBM (cluster probe: 5 lasers 810nm\u002F200mW; 4 LEDs 660nm\u002F10mW; Total Energy: 249.6 J per limb) or sham treatment 5 minutes before a fatiguing NMES protocol (80 contractions at 20% MVIC, 80 Hz, 1ms pulse width) applied to the quadriceps muscle. Assessments will be performed at baseline, immediately post-intervention, and at 24h, 48h, and 72h post-intervention. Primary outcomes include maximum and evoked isometric strength, mechanical work, and electrical muscle activity. Secondary outcomes include muscle damage (ultrasound echo-intensity), delayed onset muscle soreness (DOMS), functional performance (unilateral vertical jump), and clinical discomfort. The study seeks to determine if PBM can effectively modulate NMES-induced fatigue and muscle damage, potentially optimizing its clinical application.",[28,29,30,31,32],"Photobiomodulation","Fatigue","Discomfort","Electrical Stimulation","Muscle Damage",[28,29,30,32,34],"Electrical stimulation","RECRUITING","2026-06-24",{"date":38,"type":39},"2026-06-25","ACTUAL",{"date":41,"type":22},"2026-06-01",{"date":43,"type":22},"2026-09-30",{"name":45,"class":46},"Federal University of Rio Grande do Sul","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":17,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":47},"100637313","impact-of-neuromuscular-control-with-and-without-electrical-stimulation-and-long-term-effect-of-kinetic-chain-exercises-in-multidirectional-shoulder-instability-patients-100637313","NCT07611006","Impact of Neuromuscular Control With and Without Electrical Stimulation and Long-term Effect of Kinetic Chain Exercises in Multidirectional Shoulder Instability Patients","Inclusion Criteria:\n\n* Age: Between 20 and 50 years old.\n\nPatients with Multidirectional Shoulder Instability Must Meet the Following Conditions:\n\n(A) Generalized Joint Hypermobility: Beighton score ≥ 4\u002F9. (B) Shoulder Laxity Verified in at Least Two Directions During Clinical Examination (must meet A and B, or A and C): Inferior: Presence of a sulcus sign under the acromion or a positive Gagey hyperabduction test.\n\nAnterior: Positive anterior load and shift test or active shoulder external rotation \\> 85 degrees or passive shoulder external rotation \\> 90 degrees.\n\nPosterior: Positive posterior load and shift test or positive posterior jerk test.\n\n(C) Shoulder Pain for at Least Three Months Before the Start of the Study. (D) Signs of Shoulder Instability in Daily Life Without a Traumatic Cause. (E) Ability to Raise the Arm Above 120 Degrees Without Experiencing Subluxation or Dislocation of the Shoulder.\n\nExclusion Criteria:\n\n* Shoulder pain caused by trauma. History of shoulder fractures or dislocations. Cervical radiculopathy. Degenerative joint disease of the shoulder. Previous shoulder surgery. Frozen shoulder. Pain score greater than 5 during experimental movements. Redness, swelling, or open wounds on the skin within the experimental area. Sensory abnormalities. Cognitive impairment.","20 Years","50 Years",{"count":57,"type":22},60,[25],"Background: Shoulder instability is commonly observed in adolescents and young females, ranging from asymptomatic multidirectional instability (MDI) to symptomatic conditions. Patients with MDI often experience shoulder pain, muscle tension, and episodes of subluxation. This condition is associated with hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS), both characterized by generalized joint laxity and recurrent joint dislocations, significantly affecting daily activities and athletic performance. Current literature lacks clarity on the actual humeral head displacement, shoulder joint kinetics, and muscle activity characteristics during movement in patients with MDI accompanied by HSD or hEDS. Additionally, the effects of electrical stimulation on different shoulder muscles and its impact on humeral head displacement in MDI patients remain to be validated.\n\nObjective: The purposes of this study are to (1) examine whether patients with hEDS\u002FHSD and MDI have increased humeral head translation compared to healthy controls during three isometric contraction ; (2) investigate the relationship between humeral head translation and associated muscle activity during three isometric exercises ; (3) examine the effect of NMES and NMCT to humerus\u002Fscapula muscles on humeral head translations in MDI patients with hEDS\u002FHSD Outcome measurements: The primary outcomes include changes in acromiohumeral distance (AHD) or humeroglenoid distance (HGD) under four conditions (no stimulation, NMCT, BLH\u002FInfraspinatus\u002FMD stimulation, and SA stimulation) during three isometric contractions (shoulder flexion, horizontal adduction, and fully extended elbow holding weight).\n\nThe secondary outcomes assess muscle activation differences in BLH, infraspinatus, MD, UT, LT, and SA before and after NMCT.",[61,62,31,63,64],"Multidirectional Instability","Hypermobility Spectrum Disorder","Neuromuscular Control","Humeral Head Translation","2026-05-20",{"date":67,"type":39},"2026-05-28",{"date":69,"type":39},"2025-11-09",{"date":71,"type":22},"2026-07-30",{"name":73,"class":46},"National Taiwan University Hospital",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":23,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":47},"100469661","conditioning-electrical-stimulation-to-improve-outcomes-in-cubital-tunnel-syndrome-100469661","NCT05395715","Conditioning Electrical Stimulation to Improve Outcomes in Cubital Tunnel Syndrome","Conditioning Electrical Stimulation Enhances Recovery Following Surgery for Severe Cubital Tunnel Syndrome: A Double-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n1. Patients aged \\>18 yr,\n2. If signs and symptoms of severe CuTS (ie, McGowan-Goldberg grade 3) were observed,\n3. If needle EMG examination showed evidence of chronic motor axonal loss and reduced recruitment in the ulnar-innervated intrinsic hand muscles, and\n4. If electrophysiologic evidence of severe motor axonal loss with motor unit number estimation (MUNE) greater than 2 standard deviations below the normative mean.\n\nExclusion Criteria:\n\n1\\) Patients were excluded if they had concurrent nerve injury, prior surgery for CuTS or coexisting neurologic conditions","79 Years",{"count":83,"type":22},30,[25],"Cubital tunnel syndrome is the second most common compression neuropathy. In severe cases, functional recovery, even with surgery, is often poor. Therefore, alternative adjunct treatments capable of increasing the speed of nerve regeneration are much needed.",[87,31],"Cubital Tunnel Syndrome",[89,90,34,91,92,93,94],"Cubital tunnel syndrome","Nerve regeneration","Functional outcomes","Randomized control trial","Surgery","Peripheral nerve regeneration","2026-02-04",{"date":97,"type":39},"2026-02-09",{"date":99,"type":39},"2022-04-01",{"date":101,"type":22},"2028-06-28",{"name":103,"class":46},"University of Alberta"]