[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"electroconvulsive-therapy-treated-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:electroconvulsive-therapy-treated-patients":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100578902","the-effect-of-a-music-intervention-on-postictal-agitation-in-electroconvulsive-therapy-patients-100578902",false,"NCT06817330","The Effect of a Music Intervention on Postictal Agitation in Electroconvulsive Therapy Patients","the Effect of a MUsic Intervention on poStictal Agitation in Electroconvulsive Therapy Patients: the MUSE Trial","MUSE","Inclusion Criteria:\n\n* Patients undergoing ECT treatment for depression (including depression as part of bipolar disorder)\n* Adult patients (≥18 years)\n* Hypnotic agent used is etomidate\n* Sufficient understanding of the Dutch language (in judgement of the attending physician or researcher)\n* Written informed consent by patient or legal representative\n\nExclusion Criteria:\n\n* Significant impaired hearing (defined as unable to communicate verbally or listen to music)\n* Severe neurological condition (defined as interfering with the ability to process music)\n* Patients receiving ECT for treatment of schizophrenic disorders","ALL","18 Years",{"count":20,"type":21},92,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will investigate the effect of music on postictal agitation when played peri-interventionally for patients undergoing electroconvulsive therapy for severe depression.",[27,28,29],"Music Intervention","Electroconvulsive Therapy Treated Patients","Agitation on Recovery From Sedation",[31,32,33],"music","postictal agitation","electroconvulsive therapy","RECRUITING","2025-12-09",{"date":37,"type":38},"2025-12-17","ACTUAL",{"date":40,"type":38},"2025-11-25",{"date":42,"type":21},"2027-02-28",{"name":44,"class":45},"Erasmus Medical Center","OTHER",2,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100600121","lma-vs-high-flow-nasal-oxygen-during-ect-in-obese-patients-100600121","NCT07093372","LMA vs High-flow Nasal Oxygen During ECT in Obese Patients","Comparison Between Laryngeal Mask and High-flow Nasal Oxygen Therapy in Obese Patients Undergoing Electroconvulsive Therapy","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients scheduled to undergo ≥ 4 electroconvulsive therapy (ECT) sessions\n* Body mass index (BMI) ≥ 30 kg\u002Fm² (WHO obesity classification)\n* American Society of Anesthesiologists (ASA) physical status class I to III\n* Provided written informed consent (by patient or legal guardian)\n\nExclusion Criteria:\n\n* Patients under 18 years of age\n* Patients with ASA class IV or V\n* Patients with anticipated dental injury risk that precludes use of a laryngeal mask airway\n* Patients or guardians who refuse participation","19 Years",{"count":56,"type":21},25,[24],"This study aims to compare two oxygenation strategies-laryngeal mask airway (LMA) ventilation and high-flow nasal cannula (HFNC)-during electroconvulsive therapy (ECT) in obese patients. Due to their physiological characteristics, obese patients are at increased risk of hypoxia during ECT under general anesthesia.\n\nAdult patients with a body mass index (BMI) ≥30 who are scheduled to undergo ECT will participate. Each participant will receive both oxygenation strategies in a fixed alternating order during four consecutive ECT sessions. The procedures will follow standard anesthesia protocols.\n\nDuring the ECT procedures and the 30-minute recovery period in the post-anesthesia care unit, we will monitor the occurrence of hypoxia (SpO₂ \\\u003C92%), ventilator parameters, vital signs, postoperative confusion within 24 hours, and any reports of dental discomfort. This information will help assess the safety and clinical utility of each oxygenation method for obese patients receiving ECT.",[28,60],"Obesity",[33,62,63],"obesity","ventilation strategy","NOT_YET_RECRUITING","2025-07-23",{"date":67,"type":38},"2025-07-30",{"date":69,"type":21},"2025-08-01",{"date":71,"type":21},"2026-07-31",{"name":73,"class":45},"Eulji University Hospital",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":96},"100421121","neural-biomarkers-of-electroconvulsive-therapy-response-100421121","NCT04763655","Neural Biomarkers of Electroconvulsive Therapy Response","Neural Biomarkers of Electroconvulsive Therapy Response in Schizophrenia","Inclusion Criteria:\n\n1. current positive symptoms rated ≥4 (moderate) on one or more of these BPRS 53 items: hallucinatory behavior, unusual thought content, suspiciousness, conceptual disorganization;\n2. has failed at least one trial of treatment with antipsychotic drug, lasting 6 weeks in duration,\n3. competent and willing to sign informed consent;\n4. for women, negative pregnancy test and agreement to use a medically accepted birth control method; and\n5. Diagnostic and Statistical Manual (DSM)-IV diagnosis of schizophrenia, schizoaffective or schizophreniform disorder.\n\nExclusion Criteria:\n\n1. serious neurological or endocrine disorder;\n2. any medical condition which requires treatment with a medication with psychotropic effects;\n3. significant risk of suicidal or homicidal behavior;\n4. cognitive (MMSE ≤ 23) or language limitations that would preclude subjects providing informed consent;\n5. contraindications to treatment with electroconvulsive therapy;\n6. contraindications to magnetic resonance imaging (e.g. pacemaker)","80 Years",{"count":83,"type":21},75,[24],"In the proposed study, the investigators will utilize resting-state functional MRI (fMRI) and structural MRI-based electrical field modeling to study the effect of electroconvulsive therapy on human neural circuitry. Our study will recruit patients who are beginning treatment with bilateral electroconvulsive therapy (N=75). Our design will be longitudinal where patients will be followed up until their 8th week electroconvulsive therapy clinically. The primary measure of interest will be the slope of clinical change estimated with mixed effect modeling (see Approach). Secondary measures will be the cognitive performance change between baseline and the 8th week electroconvulsive therapy time point.",[28],"2024-09-27",{"date":89,"type":38},"2024-10-01",{"date":91,"type":38},"2020-04-01",{"date":93,"type":21},"2025-07-01",{"name":95,"class":45},"Northwell Health",1]