[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"electroencephalographydrug-effects\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:electroencephalographydrug-effects":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100636152","comparison-of-maintenance-of-propofol-and-sevoflurane-spectral-study-100636152",false,"NCT07561970","COmparison of Maintenance of Propofol And Sevoflurane Spectral Study","Comparison of EEG Power Spectrum During Maintenance of Anesthesia With Propofol Versus Sevoflurane","COMPASS","Inclusion Criteria: Adult patients undergoing elective electrophysiological interventions, such as atrial fibrillation ablation procedures, under general anesthesia\n\n* Capable to give informed consent\n* French-speaking patients\n\nExclusion Criteria:\n\n* Need for a premedication with benzodiazepine before anesthesia\n* Reduced left ventricular ejection fraction (\\\u003C 50%) or underlying cardiac pathology requiring a more balanced anesthesia (administration of benzodiazepine and\u002For ketamine during anesthesia)\n* Preoperative MoCA score \\\u003C 26\u002F30 (for patients \\> ou = 55 years old)\n* Patients treated with anti-epileptic drugs\n* Patients treated with benzodiazepines (ex: for anxiolysis or sleep disorders)\n* Emergencies\n* Morbid obesity (BMI \\> 40kg\u002Fm2)\n* Background of severe postoperative nausea\u002Fvomit","ALL","18 Years",{"count":20,"type":21},280,"ESTIMATED","INTERVENTIONAL",[24],"NA","Lower EEG alpha band power is currently extensively studied as a potential biomarker of brain vulnerability. No previous study has evaluated whether there was a difference in EEG power spectrum ranges between propofol and sevoflurane, the two main anesthetic agents for maintenance of general anesthesia, in order to define a cut-off value for the prediction of a higher risk of postoperative delirium.\n\n* Primary objective: comparison of EEG alpha power (dB) during maintenance of anesthesia with propofol and sevoflurane using data available in the NeuroSense® depth-of-anesthesia monitoring\n* Secondary objectives: comparison of other EEG frequency bands during maintenance of anesthesia with propofol and sevoflurane using data from the NeuroSense® depth-of-anesthesia monitoring",[27],"Electroencephalography\u002FDrug Effects",[29,30],"intraoperative electroencephalography","alpha-band power","RECRUITING","2026-04-24",{"date":34,"type":35},"2026-05-01","ACTUAL",{"date":37,"type":35},"2026-04-13",{"date":39,"type":21},"2027-12",{"name":41,"class":42},"Cliniques universitaires Saint-Luc- Université Catholique de Louvain","OTHER"]