[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"electrolytes\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:electrolytes":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100632512","validation-of-a-regional-citrate-anticoagulation-protocol-in-critically-ill-patients-on-continuous-renal-replacement-therapy-100632512",false,"NCT07514650","Validation of a Regional Citrate Anticoagulation Protocol in Critically Ill Patients on Continuous Renal Replacement Therapy","CRRT","Inclusion Criteria\n\n* Age ≥18 years\n* Admission to the intensive care unit (ICU)\n* Diagnosis of acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT)\n* Use of regional citrate anticoagulation during CRRT Exclusion Criteria\n* Known allergy or intolerance to citrate\n* Contraindications to citrate anticoagulation (e.g., severe liver failure or severe metabolic disorders affecting citrate metabolism)\n* Pregnancy or breastfeeding","ALL","18 Years",{"count":19,"type":20},43,"ESTIMATED","INTERVENTIONAL",[23],"NA","The objective of this study is to evaluate the effectiveness of a modified continuous renal replacement therapy (CRRT) protocol in maintaining electrolyte balance in adult patients with acute kidney injury (AKI) admitted to the intensive care unit (ICU).\n\nThe study assesses whether the use of continuous venovenous hemodiafiltration (CVVHDF) with post-filter replacement under citrate anticoagulation reduces electrolyte losses and the need for electrolyte supplementation compared with standard dialytic CRRT.\n\nParticipants receiving standard CRRT will be compared with those treated with the modified protocol.\n\nThe duration of participation corresponds to the period during which CRRT is required. Data collection will cease once CRRT is discontinued.",[26,27,28,29],"Acute Kidney Injury","ICU Patients","Continuous Renal Replacement Therapy (CRRT)","Electrolytes",[31,26,32,33,34,29],"Regional Citrate Anticoagulation","ICU patients","Continuous Renal Replacement Therapy","Diluted citrate","RECRUITING","2026-04-01",{"date":38,"type":39},"2026-04-07","ACTUAL",{"date":41,"type":39},"2024-11-24",{"date":43,"type":20},"2026-11",{"name":45,"class":46},"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau","OTHER"]