[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"emergency-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:emergency-surgery":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,72,102],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100628781","hemodynamic-effects-of-intravenous-paracetamol-in-patients-undergoing-emergency-laparotomy-100628781",false,"NCT07466108","Hemodynamic Effects of Intravenous Paracetamol in Patients Undergoing Emergency Laparotomy","Hemodynamic Effects of Intravenous Paracetamol in Patients Undergoing Emergency Laparotomy: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients, ASA I-III undergoing emergency laparotomy\n\nExclusion Criteria:\n\n* Severe cardiac morbidities (impaired contractility with ejection fraction \\\u003C 40%, heart block, arrhythmias, tight valvular lesions)\n* Hemodynamically unstable patients (defined as patients with MAP \\\u003C 65 mmHg or need vasopressor to maintain MAP\\>65 mmHg).\n* Patients with high shock index (heart rate \u002F systolic blood pressure \\>1)\n* Pregnant or lactating women,\n* Allergy of any of the study drugs","ALL","21 Years","65 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","Emergency laparotomy is a high-risk procedure often performed in patients with severe physiological derangements due to sepsis, making perioperative management challenging. Although multimodal analgesia is essential, options are often limited by factors such as hemodynamic instability, renal dysfunction, and coagulopathy. Intravenous paracetamol is commonly recommended for perioperative analgesia because of its opioid-sparing effect, but evidence suggests it may cause hypotension through peripheral vasodilation, particularly in critically ill patients. Most data on this effect come from observational studies, and evidence regarding its intraoperative hemodynamic impact remains limited.",[27,28,29],"Paracetamol","Hypotension Drug-Induced","Emergency Surgery","RECRUITING","2026-03-18",{"date":33,"type":34},"2026-03-20","ACTUAL",{"date":31,"type":34},{"date":37,"type":21},"2026-09",{"name":39,"class":40},"Cairo University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":53,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":41},"100582001","preoperative-hemoglobin-and-acute-kidney-injury-in-emergency-surgery-100582001","NCT06857630","Preoperative Hemoglobin and Acute Kidney Injury in Emergency Surgery","The Association Between Preoperative Hemoglobin and Acute Kidney Injury in Emergency Surgery: A Prospective Observational Study","Inclusion Criteria:\n\n* Patients undergoing emergency non-cardiac surgery\n\nExclusion Criteria:\n\n* Known renal failure\n* Need for reoperation within 48 hours postoperatively\n* Exit status within 48 hours postoperatively\n* Known hematological disease\n* Known kidney transplantation\n* Urgent surgery planned due to urinary system related diseases\n* Patients who did not accept to participate in the study","18 Years","80 Years",{"count":52,"type":21},420,"2 Years","OBSERVATIONAL","Optimization of hemoglobin levels for organ perfusion is essential, especially in critically ill patients. Although anemia is associated with severe organ failure, especially in coronary artery disease, the effects of blood transfusion or various interventions to increase hemoglobin levels on outcomes continue to be debated. The effects of hemoglobin levels in emergency surgery patients on the development of postoperative AKI have been investigated in a small number of studies in the literature, and clear results have not yet been reported. This study was designed to evaluate the effect of hemoglobin levels on the development of AKI after adjustment for known predictive factors.",[29,57,58],"Acute Kidney Injury","Hemoglobin",[60,61,62,58],"Acute kidney injury","Emergency surgery","Risk factor","2026-03-13",{"date":65,"type":34},"2026-03-17",{"date":67,"type":34},"2025-01-01",{"date":69,"type":21},"2027-05-01",{"name":71,"class":40},"Samsun University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":89,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":41},"100558744","acute-preoperative-pain-and-chronic-post-surgical-pain-in-emergency-surgery-100558744","NCT06555107","Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery","POCSE","Inclusion Criteria:\n\n* Age ≥18 years old.\n* Emergency orthopaedic and\u002For abdominal surgery.\n* Informed consent.\n* Affiliation to a social security scheme\n\nExclusion Criteria:\n\n* Intraoperative complications that are life-threatening or require the surgical procedure to be discontinued.\n* Post-operative intensive care unit admission.\n* Ambulatory surgery.\n* Endoscopic surgery.\n* Repeat surgery at the same site in less that 3months.\n* Pregnant or breast-feeding patients.\n* Patients under guardianship or deprived of liberty.\n* Patients suffering from psychiatric pathologies.\n* Patients suffering from neurodegenerative pathologies.\n* Patients for whom self-assessment of pain using a numerical scale (0-10) cannot be carried out (non-communicative patients, non-French-speaking patients, and so on).",{"count":80,"type":21},693,[24],"Studies evaluating postoperative pain as a risk factor for CPSP are almost exclusively carried out in the context of scheduled surgery. As a result, the preoperative pain studied as a risk factor for chronicity is essentially a state of pain that has persisted for several weeks or even several months.\n\nIn emergency surgeries, patients are subject to acute preoperative pain of varying intensity and the duration of which may vary by a few days. A few studies have highlighted the intensity of acute preoperative pain as a factor favouring moderate to severe postoperative pain. At this point, no study has addressed the long-term consequences of this intense preoperative pain the emergency context.\n\nAn evaluation in the field of emergency surgery, where the preoperative pain is often intense and limited in time, would enable us to identify more precisely the impact of acute pain on the incidence of CPSP.\n\nThe investigators are hypothesising that the occurrence of CPSP at 3 months in patients undergoing emergency orthopaedic or abdominal surgery is associated with acute preoperative pain.",[84,85,29,86,87,88],"Chronic Postsurgical Pain","Acute Pain","Opioid","Postoperative Pain","Risk Factors",[90,84,85,91,92,87],"risk factors","emergency surgery","opioid","2026-01-15",{"date":95,"type":34},"2026-01-16",{"date":97,"type":34},"2024-08-29",{"date":99,"type":21},"2027-04",{"name":101,"class":40},"Centre Hospitalier Universitaire, Amiens",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":112,"conditions":113,"keywords":121,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":41},"100594226","prognosis-of-veno-venous-extracorporeal-membrane-oxygenation-in-emergency-thoracic-surgery-100594226","NCT07016685","Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery","Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery","PECUR","Inclusion Criteria:\n\n* Adults ≥ 18 years\n* VV-ECMO initiated during or after emergency thoracic surgery\n* No opposition to data use\n\nExclusion Criteria:\n\n* Pregnant women\n* Veno-Arterial ECMO patients\n* Patients under legal protection",{"count":111,"type":21},380,"Veno-vneous extracorporeal membrane oxygenation (VV-ECMO) is an established support strategy for acute respiratory failure, but its role in the perioperative management of emergency thoracic surgery remains poorly defined. This retrospective, multicenter, observational study aims to assess the clinical outcomes and prognostic factors in this high-risk population. Patients undergoing emergency thoracic procedures requiring VV-ECMO will be compared to a control cohort of patients treated with VV-ECMO for medical respiratory failure. Data will be collected from two French academic centers (CHU Amiens-Picardie and CHU Dijon).",[114,115,29,116,117,118,119,120],"VV-ECMO","Thoracic Surgery","ARDS","Retrospective Cohort","Propensity Score Matching","Mortality","ECMO Outcomes",[122,114,91,116,123,124,125,126],"thoracic surgery","retrospective cohort","propensity score matching","mortality","ECMO outcomes","2025-06-12",{"date":129,"type":34},"2025-06-13",{"date":131,"type":34},"2025-06-01",{"date":133,"type":21},"2026-04",{"name":101,"class":40}]