[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"emotion-regulation-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:emotion-regulation-disorders":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100641392","hybrid-dialectical-behavior-therapy-for-veterans-to-further-reduce-emotion-regulation-problems-and-trauma-symptoms-100641392",false,"NCT07652645","Hybrid Dialectical Behavior Therapy for Veterans to Further Reduce Emotion Regulation Problems and Trauma Symptoms","REfreshment of Dialectical Behaviour Therapy for Veterans to Further Reduce Symptoms and Prevent Relapse of Post-traumatic Stress Disorder and Emotion Regulation Symptoms by Guided Self-Help","REFRESH","Inclusion Criteria:\n\n* Adult veteran (18 years or older), treated at Sinai Center, with knowledge of DBT\n* Primairy diagnosis of PTSD, determined with CAPS-5, resulting from war-related traumas\n* Stable for four weeks on their medication (type and doses)\n* Able to to do online homework assignments and communicate with their therapist via an eHealth platform\n* Dutch speaking\n\nExclusion Criteria:\n\n* Chronic psychosis (psychotic features as comorbidity from PTSD is allowed) or bipolar disorder type 1\n* IQ below 80 or cognitive disorders\n* Severe self-harming behaviour, such as auto-mutilation or suicidal ideations as main problem\n* Following day treatments or other intensive treatment for residual symptoms","ALL","18 Years",{"count":20,"type":21},24,"ESTIMATED","INTERVENTIONAL",[24],"NA","Around 10% of post-active veterans experience post-traumatic stress disorder (PTSD) many years post-mission. PTSD in veterans is frequently associated with challenges in emotion regulation, aggression, suicidality, and financial and psychosocial stress. In 2018, a 12-week clinical treatment programme, the Veterans Intensive Treatment Unit (VIBU), was developed for veterans experiencing these psychiatric symptoms, for whom conventional treatments had proven ineffective. The VIBU provides patients with trauma-focused and dialectical behaviour therapy (DBT). A recent study revealed that the VIBU was effective in reducing psychiatric symptoms. However, a recurrence of symptoms was observed in patients a few months after discharge. Consequently, an aftercare programme consisting of hybrid DBT is offered to consolidate and repeat the DBT skills and apply them in daily life.",[27,28,29],"PTSD","Emotion Regulation Disorders","Substance Abuse",[31,27,32,33,34],"Emotional dysregulation","DBT","Hybrid DBT","Veterans","RECRUITING","2026-06-11",{"date":38,"type":39},"2026-06-17","ACTUAL",{"date":41,"type":39},"2026-06-01",{"date":43,"type":21},"2028-10",{"name":45,"class":46},"Arkin","INDUSTRY",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":47},"100588054","cognitive-remediation-therapy-for-schizophrenia-effects-on-eeg-and-emotional-regulation-100588054","NCT06936397","Cognitive Remediation Therapy for Schizophrenia: Effects on EEG and Emotional Regulation","A Randomized Controlled EEG-GSR Study on the Effects of Cognitive Remediation Therapy on Neurophysiological and Emotional Regulation Markers in Schizophrenia","CRT-SCHZ","Inclusion Criteria (Schizophrenia Group):\n\n* Diagnosed with schizophrenia according to DSM-5 criteria\n* Age between 18 and 55 years\n* Clinically stable (no hospitalization or medication change within 1 month)\n* Minimum primary school education\n* Able to provide informed consent\n* Right-handed (for EEG protocol consistency)\n\nInclusion Criteria (Healthy Control Group):\n\n* No history of psychiatric or neurological disorders\n* Age- and gender-matched to schizophrenia group\n* No current medication affecting CNS\n* Able to provide informed consent\n* Right-handed\n\nExclusion Criteria (Both Groups):\n\n* Current or past substance use disorder (within the past year)\n* Comorbid neurological illness (e.g., epilepsy, traumatic brain injury)\n* Current use of benzodiazepines or medications that significantly affect cognitive function\n* Intellectual disability or MoCA score \\\u003C 20\n* Visual or hearing impairments that could interfere with task performance\n* Participation in a psychological intervention in the last 3 months",true,"55 Years",{"count":59,"type":21},60,[24],"This study aims to determine whether Cognitive Remediation Therapy (CRT) can improve attention, memory, and emotional regulation in people with schizophrenia. CRT is a structured program that includes exercises to strengthen cognitive skills such as problem-solving, working memory, and emotion regulation.\n\nThe study will recruit 60 participants: 30 individuals with schizophrenia and 30 healthy individuals of similar age and gender. Those with schizophrenia will be randomly assigned to either receive CRT or be placed on a waitlist without therapy. All participants will undergo non-invasive brain activity (EEG) and emotional response (GSR) recordings before and after the therapy.\n\nThe study's main question is: Does participating in a 12-week CRT program improve brain-based markers of attention and emotional regulation in people with schizophrenia?\n\nAdditional tests, such as memory and emotion recognition tasks and self-report questionnaires, will help assess changes in thinking skills and emotional well-being. The study may help better understand how CRT affects both brain function and quality of life in schizophrenia.",[63,64,28],"Schizophrenia Disorders","Cognitive Dysfunction",[66,67,68,69,70,71,72,73,74,75],"Cognitive Remediation Therapy","Schizophrenia","EEG","GSR","Emotion Regulation","Executive Function","P300","Mismatch Negativity","Neurophysiological Biomarkers","Psychophysiology","2025-04-13",{"date":78,"type":39},"2025-04-20",{"date":80,"type":39},"2025-03-15",{"date":82,"type":21},"2025-10-15",{"name":84,"class":85},"Beykoz University","OTHER"]