[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"emotion-regulation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:emotion-regulation":35},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,45,0,25,[9,52,94,122,148,177,196,223,255,287,321,352,383,413,436,479,502,530,557,593,615,631,658,680,697],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":18,"sex":19,"minAge":20,"maxAge":21,"enrollmentInfo":22,"targetDuration":4,"studyType":25,"phases":26,"briefSummary":28,"conditions":29,"keywords":36,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100630118","bonding-before-birth-a-mhealth-intervention-for-first-time-expectant-couples-100630118",false,"NCT07483515","Bonding Before Birth: A mHealth Intervention for First-time Expectant Couples","Bonding Before Birth: A Cluster-randomized, Controlled, mHealth Trial for Developing Mindfulness and Emotional Regulation in Expectant Couples","B³","Inclusion Criteria:\n\nMothers:\n\n1. 21-50 years of age\n2. Less than 20 weeks of pregnancy, confirmed by ultrasonography upon enrolment\n3. Singleton pregnancy\n4. Nulliparous\n5. Plan to deliver in Singapore\n6. Proficient and able to respond to questionnaires in English\n7. Intends for herself and her child to stay in Singapore for the next 2 years\n8. Access to a smartphone\n9. Willing to download the study app\n10. Score of 7 or more in the Edinburgh Postnatal Depression Scale\n\nFathers:\n\n1. 21-75 years of age\n2. Proficient and able to respond to questionnaires in English\n3. Intends for himself and his child to stay in Singapore for the next 2 years\n4. Access to a smartphone\n5. Willing to download the study app\n\nExclusion Criteria:\n\nMothers:\n\n1. Any pre-existing or history of psychotic depression, schizophrenia, and bipolar disorders\n2. Currently on oral\u002FIV steroids and\u002For thyroid medication\n3. History of thyroid disease\n4. Pregnant using assisted reproductive technologies\n5. Multiple pregnancies\n6. Currently enrolled in interventional randomised controlled trials\n7. Responded \"Yes, quite often\" to EPDS item 10 (\"The thought of harming myself has occurred to me\")\n\nFathers:\n\n1\\. Currently enrolled in interventional randomised controlled trials",true,"ALL","21 Years","75 Years",{"count":23,"type":24},572,"ESTIMATED","INTERVENTIONAL",[27],"NA","Emotional regulation is a key component of reducing parenting stress, a sense of self-efficacy, and thus successful parenting, child outcomes, and productivity amongst working parents. However, few interventions begin building these necessary components in pregnancy prior to the extremely stressful period immediately post-partum, where little trait and behavioural modification occurs. More importantly, most interventions overlook the importance of having both partners, despite fathers\u002Fpartners playing a significant role in influencing maternal stress and mood symptoms.\n\nThis goal of this study is to examine whether short weekly exercises delivered through a mobile app can help first-time parents feel better emotionally during pregnancy. These exercises are designed to help people manage their emotions and stress. Researchers want to know if doing these exercises, along with getting weekly feedback and encouragement, can reduce signs of depression and improve emotional control.\n\nExpecting mothers and fathers who are having their first child may be able to join the study if they meet certain conditions. Participants should be planning to stay in Singapore for the next two years and be comfortable using a smartphone and answering questions in English. Participants may benefit from learning new ways to manage stress and emotions, which could help improve their mental health.\n\nParticipants will wear a Fitbit watch to track activity. They will complete a short weekly survey about their well-being during pregnancy and a monthly survey about their work productivity until six months after the baby is born. They will also answer online surveys about their health, relationships, and background at the start, three times during pregnancy, and three times after birth. In addition, they will visit the research lab twice to take part in tasks that measure thinking and behaviour.",[30,31,32,33,34,35],"Anxiety","Pregnancy","Parenting Self-efficacy","Stress (Psychology)","Depression","Emotion Regulation",[37,38,35,34,31,30],"Reinforcement Learning","Micro-randomization","RECRUITING","2026-06-28",{"date":42,"type":43},"2026-06-30","ACTUAL",{"date":45,"type":24},"2026-07-06",{"date":47,"type":24},"2028-12-31",{"name":49,"class":50},"Institute for Human Development and Potential (IHDP), Singapore","OTHER",1,{"id":53,"slug":54,"hasResults":12,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":18,"sex":19,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":25,"phases":64,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":51},"100644295","sharing-tales-that-teach-shared-picturebook-reading-for-early-childhood-emotional-and-cognitive-development-100644295","NCT07666802","Sharing Tales That Teach: Shared Picturebook Reading for Early Childhood Emotional and Cognitive Development","Sharing Tales That Teach: An RCT of Emotion-Focused Shared Picturebook Reading Versus Standard Dialogic Reading to Support Emotion Regulation and Executive Function in Caregiver-Child Dyads","STTT","Inclusion Criteria:\n\n* Child aged 4 to 5 years at baseline assessment\n* Child enrolled in a participating state primary school\n* At least one primary caregiver willing to participate in shared reading activities and study assessments\n* Caregiver has sufficient proficiency in English to engage with intervention materials and questionnaires\n\nExclusion Criteria:\n\n* Child has an identified sensory impairment, such as uncorrected hearing or vision difficulties, that would impede engagement with study tasks\n* Family is unable to commit to baseline and follow-up assessments","48 Months","59 Months",{"count":63,"type":24},200,[27],"Sharing Tales That Teach is a randomised study of a shared picturebook reading programme for 4- to 5-year-old children and their primary caregivers. The study will test whether a caregiver-delivered, emotion-focused shared reading programme leads to greater improvements in children's emotion regulation than a standard dialogic shared reading programme.\n\nEmotion regulation refers to children's developing ability to understand, express and manage emotions in ways that support learning, relationships and wellbeing. These skills are closely linked with executive function, including children's ability to remember instructions, control impulses and shift flexibly between activities. Shared picturebook reading may provide a natural, low-cost way for caregivers to support these skills through everyday interaction.\n\nFamilies in the randomised part of the study will be allocated to one of two 8-week shared reading programmes. In the emotion-focused group, caregivers will receive training in strategies such as naming emotions, discussing why characters feel as they do, talking about consequences of emotions and modelling ways to manage feelings. In the comparison group, caregivers will receive training in standard dialogic picturebook reading strategies, such as naming, describing, sequencing and asking open questions, without an explicit focus on emotions or emotion regulation. Both groups will use the same picturebooks and will be asked to complete three shared reading sessions per week at home.\n\nThe main hypothesis is that children in the emotion-focused shared reading group will show greater improvement in emotion regulation from baseline to 12-month follow-up than children in the standard dialogic shared reading group. The study will also examine whether the programme affects children's executive function, caregiver wellbeing and caregiver emotion regulation. Additional exploratory analyses will examine caregiver-child interaction processes and whether caregiver or child characteristics are associated with different intervention effects.\n\nThe study will recruit caregiver-child dyads through state primary schools in Greater London. Children will complete age-appropriate tasks and caregivers will complete questionnaires at baseline and follow-up. A laboratory subsample may also complete additional behavioural, observational and neurophysiological assessments. The study is low risk, non-invasive and does not involve medical treatment.",[67,68,35],"Child Development","Executive Functions (EF)",[35,70,71,72,73,74,75,76,77,78,79,80,81,82,83],"Inhibitory Control","Cognitive Flexibility","Working Memory","Self-Control","Shared Reading","Dialogic Reading","Picturebooks","Early Childhood","Preschool Children","Caregiver-Child Dyads","Randomized Controlled Trial","Randomised Controlled Trial","Behavioural Intervention","Developmental Cognitive Neuroscience","NOT_YET_RECRUITING","2026-06-18",{"date":87,"type":43},"2026-06-24",{"date":89,"type":24},"2026-09",{"date":91,"type":24},"2028-08-01",{"name":93,"class":50},"University of Greenwich",{"id":95,"slug":96,"hasResults":12,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":12,"sex":19,"minAge":102,"maxAge":103,"enrollmentInfo":104,"targetDuration":4,"studyType":25,"phases":106,"briefSummary":107,"conditions":108,"keywords":111,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":51},"100584816","an-interactive-education-program-to-reduce-high-risk-behavior-in-adolescents-ph-ii-itrac-hero-100584816","NCT06894277","An Interactive Education Program to Reduce High Risk Behavior in Adolescents Ph II (iTRAC HERO)","An Interactive Education Program to Reduce High Risk Behavior in Adolescents Ph II","iTRAC-HERO","Inclusion Criteria:\n\n* Attending 7th grade\n* Between 12 and 14 years old\n* Parent\u002Fguardian speaks English or Spanish\n* Attending participating school\n\nExclusion Criteria:\n\n* Unable to read at a 4th grade level\n* Have a sibling who has participated in the study\n* Have a development disorder","12 Years","14 Years",{"count":105,"type":24},120,[27],"Using the efficacious iTRAC intervention to enhance emotion regulation competencies as a foundation, this study will create and test iTRAC-HERO to teach emotion regulation skills in the context of sexual health education.",[109,35,110],"Risky Sexual Behavior","Adolescent Behavior",[109,35,110],"2026-06-12",{"date":114,"type":43},"2026-06-16",{"date":116,"type":43},"2025-04-01",{"date":118,"type":24},"2026-08-31",{"name":120,"class":121},"Klein Buendel, Inc.","INDUSTRY",{"id":123,"slug":124,"hasResults":12,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":18,"sex":19,"minAge":129,"maxAge":4,"enrollmentInfo":130,"targetDuration":4,"studyType":25,"phases":132,"briefSummary":133,"conditions":134,"keywords":138,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":51},"100643565","ai-based-communication-simulation-and-human-library-narratives-100643565","NCT07637461","AI-Based Communication Simulation and Human Library Narratives.","Pediatric Nursing Education Integrating AI-Based Communication Simulation and Human Library Narratives: Evaluating Effects on Students' Communication, Empathy, and Emotion Regulation","Inclusion Criteria:\n\n1. Must be 18 years of age or older\n2. Must have completed required nursing courses including Anatomy, Physical Examination and Assessment (with Laboratory), and Basic Nursing (with Internship)\n3. Must be willing to participate in the research and agree to complete the relevant questionnaire.\n\nExclusion Criteria:\n\n1. Individuals with mental illness or cognitive impairment that may affect their participation in the research or the reliability of the data","18 Years",{"count":131,"type":24},40,[27],"This research plan aims to establish an effectiveness assessment system for promoting clinical communication, empathy, and emotion regulation in pediatric nursing students through a combination of AI communication simulation and human library narrative.\n\nThis study sets five specific objectives:\n\n1. To develop and implement a pediatric nursing teaching model that integrates AI communication simulation and human library narrative.\n2. To evaluate the effectiveness of this teaching model in improving nursing students' clinical communication skills.\n3. To examine the effectiveness of this teaching intervention in enhancing nursing students' empathy.\n4. To explore the impact of this teaching intervention on nursing students' emotion regulation abilities.\n5. To understand students' learning experiences, feelings, changes in emotion regulation, and suggestions for improvement regarding this integrated teaching intervention.",[135,35,136,137],"Nursing Students","Empathy","AI (Artificial Intelligence)",[135,35,136,137],"2026-06-04",{"date":141,"type":43},"2026-06-09",{"date":143,"type":24},"2026-08-01",{"date":145,"type":24},"2027-07-31",{"name":147,"class":50},"National Defense Medical University, Taiwan",{"id":149,"slug":150,"hasResults":12,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":154,"eligibilityCriteria":155,"healthyVolunteers":12,"sex":19,"minAge":129,"maxAge":156,"enrollmentInfo":157,"targetDuration":4,"studyType":25,"phases":159,"briefSummary":160,"conditions":161,"keywords":164,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":176},"100423432","manage-emotions-to-reduce-aggression-mera-100423432","NCT04793776","Manage Emotions to Reduce Aggression (MERA)","Manage Emotions to Reduce Aggression - MERA: A Brief Aggression Treatment for Veterans With PTSD Symptoms","MERA","Inclusion Criteria:\n\n1. Male and female Veterans who deployed to combat zones since 9\u002F11.\n2. Currently meets criteria for full or subthreshold PTSD, determined by the Clinician-Administered PTSD Scale for DSM-5\n3. Engaged in at least 3 self-reported aggressive acts (e.g., yelling, throwing objects, hitting objects\u002Fpeople) in the last month, measured by the Overt Aggression Scale\n4. Impulsive aggression is his\u002Fher primary form of aggression, determined by the Impulsive Premeditated Aggression Scale\n5. Each Veteran must allow an independent aggression rater (live-in partner, family member, or roommate above 18 years of age)\\] verify the number of aggressive acts, using the Overt Aggression Scale.\n6. Agreement not to change psychotropic medications through the duration of the study.\n\nExclusion Criteria:\n\n1. Currently suicidal with intent of self-harm in the last week.\n2. Currently homicidal with plans to hurt a specific person.\n3. Unable to complete self-report measures.\n4. Meets diagnostic criteria for bipolar disorder or psychotic disorder.\n5. Had a psychotropic medication change within 4 weeks prior to the baseline assessment. Veterans receiving general mental health services or engaging in usual care will be allowed to participate.","64 Years",{"count":158,"type":24},204,[27],"PTSD is one of the most prevalent mental health conditions affecting Veterans who have served since 9\u002F11. Veterans with posttraumatic stress disorder (PTSD) report difficulty controlling impulsive aggression (IA). An inability to manage one's emotions (emotion dysregulation) is an underlying mechanism of IA. Reducing IA and increasing use of PTSD evidence-based psychotherapies are two critical missions for the Veterans Health Administration. The proposed research supports these missions by comparing a 3- session emotion regulation treatment (Manage Emotions to Reduce Aggression) to a control group in order to determine if MERA can reduce IA and prepare Veterans for PTSD treatment. By enhancing Veterans' abilities to cope with trauma-related emotions and feel equipped to initiate PTSD treatments, this research aims to help Veterans decrease IA and ultimately recover from PTSD.",[162,163,35],"Stress Disorders, Post-Traumatic","Aggression",[162,163,35,165,166],"Veterans","Psychotherapy",{"date":168,"type":43},"2026-06-08",{"date":170,"type":43},"2022-01-03",{"date":172,"type":24},"2026-12-30",{"name":174,"class":175},"VA Office of Research and Development","FED",2,{"id":178,"slug":179,"hasResults":12,"nctId":180,"briefTitle":181,"officialTitle":181,"acronym":4,"eligibilityCriteria":182,"healthyVolunteers":12,"sex":19,"minAge":4,"maxAge":4,"enrollmentInfo":183,"targetDuration":4,"studyType":25,"phases":185,"briefSummary":186,"conditions":187,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":188,"lastUpdatePostDateStruct":189,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":51},"100551666","testing-an-intergenerational-model-of-suicide-risk-in-mother-child-dyads-100551666","NCT06463054","Testing an Intergenerational Model of Suicide Risk in Mother-child Dyads","Inclusion Criteria:\n\n* Biological mothers with legal custody of target child between 9-11\n* Confirmed lifetime Biological mothers with legal custody of target child between 9-11\n* Confirmed lifetime history of suicidal behavior for mothers of suicidal behavior for mothers\n\nExclusion Criteria:\n\n* Any mothers and children with major medical illnesses that might be associated with organic personality changes or ER difficulties (e.g. Parkinson's Disease, seizure disorders)\n* Cardiac nervous system abnormalities that would influence physiological readings\n* Previous DBT (Dialectical Behavior Therapy) in the last six months",{"count":184,"type":24},150,[27],"The investigators are interested in learning more about how the role of mothers' emotions has on the transmission of suicide risk to children. Eligible participants will be invited to participate in a baseline assessment, and 4 follow-up assessments in the next year. This research study is a randomized control trial. Participants that choose to enroll are randomly assigned, that is by chance (like by flipping a coin) to receive DBT Skills Training or treatment as usual (TAU). Participants may also be selected for DBT skills training, it which would occur once a week for 6 months.",[35],"2026-06-02",{"date":139,"type":43},{"date":191,"type":43},"2024-04-01",{"date":193,"type":24},"2028-03-31",{"name":195,"class":50},"University of Pittsburgh",{"id":197,"slug":198,"hasResults":12,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":202,"eligibilityCriteria":203,"healthyVolunteers":18,"sex":19,"minAge":204,"maxAge":205,"enrollmentInfo":206,"targetDuration":4,"studyType":25,"phases":208,"briefSummary":209,"conditions":210,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":51},"100530896","screens-sleep-circadian-rhythms-and-electronics-in-the-evening-study-100530896","NCT06192745","SCREENS: Sleep, Circadian Rhythms, and Electronics in the EveNing Study","Experimental Effects of Light And Content From Evening Screen Media Use On Children's Sleep, Executive Functioning, And Emotion Regulation","SCREENS","Inclusion Criteria:\n\n* children between 8.0 and 11.9 year old\n* Tanner stage 1 and 2\n* live with their parent(s) (biological or legal guardian at least 50% of the time and has a primary role of caring for the child).\n* Children who sleep between 8.5 to 11 hours per night habitually\n* Children must sleep alone most nights\n* parent and child able to communicate and read and write in English\n* The child does not have to have access to a mobile device (tablet or Phone), but if they do, the primary device they use has to be an a) Android OS ≥5.0 either used only by the study child or shared with others, b) Amazon Fire OS ≥5.0 that only the child uses or c) an Apple iOS ≥14.0 that only the child uses.\n* If the child's primary device is a Android or Amazon Fired device, the parent and child agree to install Chronicle App (Android or Amazon). If the child's primary device is an Apple device, the parent and child agree to allow us to gather usage screenshots from the primary iPad or iPhone.\n* Families must live in the greater Houston area.\n\nExclusion Criteria:\n\n* child blindness or colorblindness\n* significant vision problems\n* developmental or cognitive delays\n* diagnosis of a sleep or psychiatric disorder\n* diagnosed cognitive or learning impairment affecting executive functioning (e.g., attention deficit hyperactivity disorder)\n* medical conditions that impact sleep\n* taking medications that impact sleep\n* travel beyond 2 time zones in the month before starting the study","8 Years","11 Years",{"count":207,"type":24},220,[27],"The proposed project aims to disentangle the impact of evening light exposure emitted from tablet devices from the impact of arousing media content on children's sleep regulation, circadian physiology and next-day emotion regulation and executive functioning.",[211,212,213,35],"Sleep","Circadian Rhythm","Executive Function","2026-06-01",{"date":216,"type":43},"2026-06-03",{"date":218,"type":43},"2025-01-10",{"date":220,"type":24},"2028-08-30",{"name":222,"class":50},"Baylor College of Medicine",{"id":224,"slug":225,"hasResults":12,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":18,"sex":19,"minAge":129,"maxAge":4,"enrollmentInfo":230,"targetDuration":4,"studyType":25,"phases":232,"briefSummary":233,"conditions":234,"keywords":240,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":249,"completionDateStruct":251,"leadSponsor":253,"locationsCount":51},"100512176","smartphone-based-cognitive-emotion-regulation-training-for-unpaid-primary-caregivers-of-persons-with-alzheimers-disease-100512176","NCT05949047","Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease","Biobehavioral Mechanisms of Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease","Inclusion Criteria:\n\nHealthy Adult Caregivers\n\n* Unpaid primary caregiver of patient with Alzheimer's Disease\u002FAlzheimer's Disease and Related Dementias (AD\u002FADRD)\n* At least 18 years of age, with no maximum age, provided that all other inclusion\u002Fexclusion criteria are met\n* Must be able to speak, read, and write in English\n* Must be free of any current or past DSM diagnosis (i.e. healthy adults), with the exception of current or past mood or anxiety disorders or past substance-related disorders (i.e., current or past mood or anxiety disorders and\u002For past substance-related disorders would not represent an exclusion factor)\n* Must have a smartphone. This represents any major iOS or Android-based smartphone. The smartphone will also be used for collection of ecological momentary assessment (EMA) data via SurveySignal.\n* Must provide significant level of caregiving to their care recipient\n* Must be at least minimally-stressed\n\nCognitively Impaired Adults\n\n* Must have diagnosed with Alzheimer's Disease\u002FAlzheimer's Disease and Related Dementias (AD\u002FADRD)\n* Must be the care recipient of the primary caregiver who is completing the study\n* Must be able to understand and willing to complete a questionnaire and the consent form\n* Must have minimum level of dementia symptoms\n\nExclusion Criteria:\n\nHealthy Adult Caregivers\n\n* Current or past psychiatric disorders (e.g., psychotic and personality disorders) with the exception of current or past mood or anxiety disorders or past substance-related disorders (i.e., current or past mood or anxiety disorders and\u002For past substance-related disorders would not represent an exclusion factor)\n* Currently receiving psychotherapy that specifically addresses caregiver burden\u002Fdistress or employs cognitive reappraisal as a major component\n* Significant visual, auditory, or cognitive impairment that compromises their ability to understand and complete the task\n* Caregiver participants who cease meeting inclusion criteria during the study will be dismissed from the study and compensated pro-rata.\n* Has formerly participated in a study from our lab involving the same or essentially same design (e.g., former participants who provided pilot\u002Fpreliminary data for this study)\n\nCognitively Impaired Adults\n\n* The care recipient does not wish to participate, and\u002For their caregiver does not want them to participate\n* Significant visual, auditory, or cognitive impairment that compromises their ability to understand and complete questionnaires, even with their caregiver's help will exclude them from the study\n* Has formerly participated in a study from our lab involving the same or essentially same design (e.g., former participants who provided pilot\u002Fpreliminary data for this study)",{"count":231,"type":24},270,[27],"Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD) not only exact a heavy toll on patients, they also impose an enormous emotional, physical, and financial burden on unpaid, often family, caregivers. The strain of providing care for a loved one diagnosed with AD, often across several years, is associated with elevated depression risk and poorer overall health. Emotion regulation skills represent an ideal target for psychological intervention to promote healthy coping in ADRD caregivers. The project seeks to use an experimental medicine approach to test the efficacy and biobehavioral mechanisms of a novel, relatively brief, targeted, scalable, smartphone-based cognitive emotion regulation intervention aimed at improving psychological outcomes (i.e., reducing perceived stress, caregiver burden, and depressive symptoms) in ADRD unpaid primary caregivers as well as examine potential benefits of the caregiver intervention on quality of life in care recipients. Cognitive reappraisal is the ability to modify the trajectory of an emotional response by thinking about and appraising emotional information in an alternative, more adaptive way. Reappraisal can be operationalized via two primary tactics: psychological distancing (i.e. appraising an emotional stimulus as an objective, impartial observer) and reinterpretation (i.e., imagining a better outcome than what initially seemed apparent). The project will investigate the efficacy and underlying biobehavioral mechanisms of a novel, one-week cognitive reappraisal intervention in this population, with follow-up assessments at 2 weeks, 4 weeks, and 3 months. ADRD unpaid primary caregivers will be randomly assigned to receive training in either distancing, reinterpretation, or a no regulation natural history control condition, with ecological momentary assessments of self-reported positive and negative affect, remotely- collected psychophysiological health-related biomarkers (i.e., heart rate variability data) using pre-mailed Polar H10 chest bands, and health-related questionnaire reports. Distancing training is expected to result in longitudinal reductions in self-reported negative affect, longitudinal increases in positive affect, and longitudinal increases in HRV that are larger than those attributable to reinterpretation training and no-regulation control training.",[235,236,35,237,238,239],"Caregivers","Emotions","Stress","Psychological","Psychophysiology",[241,242,243,244,245],"emotion regulation","caregiving","affective science","psychophysiology","psychoneuroimmunology","2026-05-27",{"date":248,"type":43},"2026-05-29",{"date":250,"type":43},"2023-09-14",{"date":252,"type":24},"2027-05-31",{"name":254,"class":50},"Bryan Denny",{"id":256,"slug":257,"hasResults":12,"nctId":258,"briefTitle":259,"officialTitle":260,"acronym":4,"eligibilityCriteria":261,"healthyVolunteers":12,"sex":19,"minAge":262,"maxAge":102,"enrollmentInfo":263,"targetDuration":4,"studyType":25,"phases":265,"briefSummary":266,"conditions":267,"keywords":271,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":278,"lastUpdatePostDateStruct":279,"startDateStruct":281,"completionDateStruct":283,"leadSponsor":285,"locationsCount":4},"100614574","pilot-trial-of-an-emotion-regulation-and-executive-functioning-intervention-for-self-injurious-thoughts-and-behaviors-sitbs-in-children-100614574","NCT07281365","Pilot Trial of an Emotion Regulation and Executive Functioning Intervention for Self-Injurious Thoughts and Behaviors (SITBs) in Children","Proof-of-Concept Trial of an Emotion Regulation and Executive Functioning Intervention for SITBs in Children","Inclusion Criteria:\n\n* between the ages of 7-12\n* at least one caregiver\u002Flegal guardian able to participate (more permitted)\n* experienced at least one episode of SITBs within the last month\n* ability to attend weekly sessions in-person or via telehealth\n* ability to attend baseline and 12-week assessments in-person.\n* estimated verbal IQ of 70 or greater\n\nExclusion Criteria\n\n* symptoms interfering with ability to participate in assessments\u002Ftherapy (i.e., psychosis)\n* estimated verbal IQ\\\u003C70 or previous diagnosis of intellectual development disorder\n* requiring inpatient psychiatric stabilization or high-intensity intervention to prevent hospitalization\n* active substance use\n* ward of the state","7 Years",{"count":264,"type":24},52,[27],"The goal of this study is to develop and test an outpatient intervention for preadolescents (ages 7-12) with self-injurious thoughts and behaviors (SITBs).\n\nThe main questions it aims to answer are:\n\n1. Does the newer intervention lead to better engagement of families in treatment compared to treatment as usual (TAU)?\n2. Is the new intervention feasible, acceptable, and appropriate?\n3. Does the new intervention lead to more improvements in SITBs, mental health symptoms, and treatment targets compared to TAU?\n\nPreadolescent participants with SITBs and their families will be randomized to either the new intervention or TAU, which will consist of the typical interventions the study therapist would use for preadolescents with SITBs. Participants will:\n\n1. Complete an initial baseline assessment to determine eligibility and assess SITBs, mental health symptoms, executive functioning, and emotion regulation\n2. Participate in a \\~weekly, outpatient intervention lasting around 3-4 months\n3. Complete additional assessments at mid-treatment, post-treatment, and 3-month follow-up\n4. Participate in an interview sharing their perceptions of the intervention",[268,269,270,35],"Self-injury","Suicidal Ideation and Behavior","Executive Functioning",[272,273,274,275,276,277],"Preadolescents","Children","Self-Injury","Suicidal ideation and behavior","Randomized controlled trial","Feasibility","2026-05-13",{"date":280,"type":43},"2026-05-14",{"date":282,"type":24},"2026-12",{"date":284,"type":24},"2028-05",{"name":286,"class":50},"University of Colorado, Denver",{"id":288,"slug":289,"hasResults":12,"nctId":290,"briefTitle":291,"officialTitle":292,"acronym":293,"eligibilityCriteria":294,"healthyVolunteers":18,"sex":19,"minAge":295,"maxAge":296,"enrollmentInfo":297,"targetDuration":4,"studyType":25,"phases":299,"briefSummary":300,"conditions":301,"keywords":304,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":315,"completionDateStruct":317,"leadSponsor":319,"locationsCount":51},"100623790","gutlink4kids-intervention-100623790","NCT07401212","GUTLINK4KIDS Intervention","The Impact of Chronic Consumption of Prebiotics on Cognitive and Affective Outcomes, Gut Microbiome Diversity and Composition in 3-5 Year Olds: a Double-blind Placebo-controlled, Parallel-groups Randomised Controlled Trial","GUTLINK4KIDS","Inclusion Criteria:\n\n* Parents (18 years and over) of generally healthy children aged 3-5-years-old (36-71 months) with lower dietary fibre intake than the recommended daily amount (10.4g\u002Fday in 18-47-month-olds and less than 12.6g\u002Fday in 48-60-month-olds).\n\nExclusion Criteria:\n\n* Children with a significant acute or chronic co-existing illness (including inflammatory bowel disease, functional gastrointestinal disorders, coeliac disease etc, neurodevelopmental, immunological, psychiatric, or metabolic disorders.\n* Children who have taken any pre\u002Fprobiotic supplements or antibiotic treatment within the 4 weeks prior to enrolment.\n* Children with food allergies and intolerances","3 Years","5 Years",{"count":298,"type":24},106,[27],"This study aims to investigate the chronic effects of prebiotic consumption on cognitive, behavioural and gut microbiome outcomes in children aged 3-5 years.",[302,211,303,35],"Temperament","Cognition",[305,241,306,307,308,309,310,311],"prebiotics","gut microbiome diversity","children","relative abundance","sleep","internalising symptoms","externalising symptoms","2026-04-27",{"date":314,"type":43},"2026-04-28",{"date":316,"type":43},"2026-03-02",{"date":318,"type":24},"2027-02-01",{"name":320,"class":50},"University of Reading",{"id":322,"slug":323,"hasResults":12,"nctId":324,"briefTitle":325,"officialTitle":326,"acronym":327,"eligibilityCriteria":328,"healthyVolunteers":18,"sex":19,"minAge":129,"maxAge":329,"enrollmentInfo":330,"targetDuration":4,"studyType":25,"phases":332,"briefSummary":333,"conditions":334,"keywords":338,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":344,"lastUpdatePostDateStruct":345,"startDateStruct":347,"completionDateStruct":349,"leadSponsor":350,"locationsCount":51},"100635966","act-based-group-therapy-and-mobile-application-intervention-for-emotional-eating-100635966","NCT07559552","ACT-Based Group Therapy and Mobile Application Intervention for Emotional Eating","The Effect of Acceptance and Commitment Therapy and a Mobile App on Emotional Eating, Emotion Regulation, and Psychological Flexibility in Overweight Individuals","ACT-EE","Inclusion Criteria:\n\n* Agreeing to participate in the study,\n* Being between 18-65 years of age,\n* Having a body mass index ≤ 25 (BMI ≤ 29.9),\n* Being able to read and write,\n* Having an iOS or Android smartphone,\n* Having internet access,\n* Having a home environment suitable for online sessions (having a computer\u002Fsmartphone, internet access at home, the patient being able to be alone in the room during the session, etc.),\n\nExclusion Criteria:\n\n* Having communication problems that would prevent the interview,\n* Having a diagnosis of a mental disorder, including an eating disorder, that would prevent participation in the study, or having concomitant serious medical conditions that could potentially jeopardize study participation.\n* Having undergone bariatric surgery. • Being on the waiting list for bariatric surgery.\n* Being pregnant, breastfeeding, or planning to become pregnant within the next 6 months.\n* Receiving therapy\u002Fcounseling for emotional eating and emotion regulation problems,\n* Using a mobile application for emotional eating and emotion regulation problems,","65 Years",{"count":331,"type":24},78,[27],"This study aims to evaluate the effects of an Acceptance and Commitment Therapy (ACT)-based group therapy program, combined with an ACT-based mobile app, on emotional eating, emotion regulation, and psychological flexibility in overweight individuals. Emotional eating is a condition in which individuals frequently use eating behavior as a coping mechanism for negative emotions.\n\nParticipants will be randomly assigned to intervention groups receiving ACT-based group therapy, ACT-based group therapy combined with an ACT-based mobile app, or a control group. The intervention will last six weeks and will include structured group sessions as well as mobile-based exercises, reminders, and coping strategies.\n\nOutcome measures will include emotional eating, emotion regulation, and psychological flexibility. Assessments will be conducted at baseline, post-intervention, and during the follow-up phase. The findings of this study are expected to contribute to the development of accessible and effective interventions for emotional eating.",[335,35,336,337],"Emotional Eating","Overweight","Psychological Flexibility",[339,335,35,337,340,341,342,336,343],"Acceptance and Commitment Therapy","Mobile Health (mHealth)","Mobile Application","Group Therapy","Digital Intervention","2026-04-22",{"date":346,"type":43},"2026-04-30",{"date":348,"type":24},"2026-06-15",{"date":172,"type":24},{"name":351,"class":50},"Saglik Bilimleri Universitesi",{"id":353,"slug":354,"hasResults":12,"nctId":355,"briefTitle":356,"officialTitle":357,"acronym":4,"eligibilityCriteria":358,"healthyVolunteers":18,"sex":19,"minAge":129,"maxAge":329,"enrollmentInfo":359,"targetDuration":4,"studyType":25,"phases":360,"briefSummary":361,"conditions":362,"keywords":367,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":374,"lastUpdatePostDateStruct":375,"startDateStruct":377,"completionDateStruct":379,"leadSponsor":381,"locationsCount":51},"100482169","the-social-regulation-of-threat-related-vigilance-and-arousal-100482169","NCT05558527","The Social Regulation of Threat-related Vigilance and Arousal","Effects of Trauma and Discrimination on the Social Regulation of Threat-related Vigilance and Arousal","Inclusion Criteria:\n\n* In a stable romantic relationship for 6 months or more\n* Normal vision or corrected-to-normal vision\n* Fluent in English\n\nExclusion Criteria:\n\n* If vision is corrected-to-normal, needs to use hard contact lenses, bifocal contact lenses, or glasses\n* Experienced a traumatic event within the past 4 weeks",{"count":5,"type":24},[27],"This study will examine the effects of social support on threat vigilance and arousal using eye tracking. We will also test the moderating effects of trauma and discrimination history.",[363,364,35,365,366,30],"Psychological Trauma, Historical","Discrimination, Racial","Social Interaction","Hypervigilance",[368,369,370,371,372,373],"psychological trauma","ethnoracial discrimination","hypervigilance","anticipated threat","social emotion regulation","social touch","2026-04-06",{"date":376,"type":43},"2026-04-13",{"date":378,"type":43},"2025-12-18",{"date":380,"type":24},"2029-12",{"name":382,"class":50},"University of Nevada, Reno",{"id":384,"slug":385,"hasResults":12,"nctId":386,"briefTitle":387,"officialTitle":388,"acronym":389,"eligibilityCriteria":390,"healthyVolunteers":18,"sex":19,"minAge":204,"maxAge":391,"enrollmentInfo":392,"targetDuration":4,"studyType":25,"phases":394,"briefSummary":395,"conditions":396,"keywords":400,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":404,"lastUpdatePostDateStruct":405,"startDateStruct":407,"completionDateStruct":408,"leadSponsor":410,"locationsCount":412},"100623603","pace-study-school-based-mindfulness-and-compassion-interventions-for-children-100623603","NCT07398781","PACE Study: School-Based Mindfulness and Compassion Interventions for Children","The PACE Study (Present-Moment Awareness, Attention, Compassion, Emotion Regulation): Effects of School-Based Mindfulness and Compassion Interventions","PACE","Inclusion Criteria:\n\n* Participants must be primary school students (grades 3rd-7th)\n\nExclusion Criteria:\n\n* Lack of signed consent","13 Years",{"count":393,"type":24},500,[27],"This study aims to evaluate the effects of three school-based interventions focused on mindfulness, compassion, and social-emotional learning on children's psychological well-being and higher-order cognitive functions.\n\nThe interventions are delivered in the classroom through structured experiential activities. Children are assessed before and after the interventions using standardized tests and questionnaires measuring attention, executive functions, emotional regulation, mindfulness, self-compassion, and social-emotional skills.",[397,398,399,35],"School-based Intervention","Mindfulness-based Intervention","Compassion",[401,402,241,403],"mindfulness","compassion","School","2026-03-17",{"date":406,"type":43},"2026-03-19",{"date":376,"type":24},{"date":409,"type":24},"2027-12",{"name":411,"class":50},"IRCCS Fondazione Stella Maris",4,{"id":414,"slug":415,"hasResults":12,"nctId":416,"briefTitle":417,"officialTitle":418,"acronym":4,"eligibilityCriteria":419,"healthyVolunteers":12,"sex":19,"minAge":204,"maxAge":420,"enrollmentInfo":421,"targetDuration":4,"studyType":25,"phases":423,"briefSummary":424,"conditions":425,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":427,"lastUpdatePostDateStruct":428,"startDateStruct":430,"completionDateStruct":432,"leadSponsor":434,"locationsCount":51},"100500983","evaluating-additive-effects-of-including-canines-in-regulating-together-100500983","NCT05803343","Evaluating Additive Effects of Including Canines in Regulating Together","Evaluating Additive Effects of Including Canines in Regulating Together: A Group Treatment to Address Emotion Dysregulation in Youth With Autism Spectrum Disorder","Inclusion Criteria:\n\n* Concern of emotion dysregulation (ED) as measured by a score of 6 or greater on the Emotion Dysregulation Inventory-Reactivity (EDI-R)\n* Diagnosis of autism spectrum disorder (ASD)\n* Diagnosis confirmed by an experienced ASD clinician and further supported by scoring in the range for ASD on the Autism Diagnostic Observation Schedule (ADOS-2)\n* A Full Scale Intelligence Quotient score of 65 or greater on the Weschler Abbreviated Scale Intelligence (WASI-II)\n* English is the primary language\n* Family willing to keep prescribed medication stable over the course of the study period\n\nExclusion Criteria:\n\n* Participant has a phobia toward or is allergic to canines\n* Participant has a history of aggression toward animals\n* Participant has had any physical aggression toward other children outside the home in the past 2 weeks that resulted in injury\n* Presence of comorbid major neuropsychiatric illness warranting other treatment approaches as determined by the study clinician(s) including substance use disorders, psychotic disorders\u002Fschizophrenia, and bipolar disorder, among others\n* Presence of any major sensory impairment that would limit participating in the material including blindness or uncorrected hearing loss\n* A legal guardian is not available to provide informed consent","15 Years",{"count":422,"type":24},240,[27],"The primary objective is to evaluate the potential additive effect of animal-assisted intervention (AAI) on a manualized behavioral treatment targeting emotion dysregulation (ED) in children with autism spectrum disorder (ASD).\n\nAim 1: Evaluate whether Regulating Together-Canine demonstrates earlier and greater improvement in emotion dysregulation than Regulating Together-Standard.\n\nAim 2: Evaluate if Regulating Together-Canine increases child engagement and learning compared to Regulating Together-Standard.\n\nExploratory Aim: Explore association of physiological arousal (via heart rate tracking) with emotion dysregulation, treatment engagement, and learning.",[426,35],"Autism Spectrum Disorder","2026-03-16",{"date":429,"type":43},"2026-03-18",{"date":431,"type":43},"2023-02-28",{"date":433,"type":24},"2027-08-31",{"name":435,"class":50},"Children's Hospital Medical Center, Cincinnati",{"id":437,"slug":438,"hasResults":12,"nctId":439,"briefTitle":440,"officialTitle":441,"acronym":4,"eligibilityCriteria":442,"healthyVolunteers":12,"sex":19,"minAge":129,"maxAge":443,"enrollmentInfo":444,"targetDuration":4,"studyType":25,"phases":445,"briefSummary":446,"conditions":447,"keywords":462,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":316,"lastUpdatePostDateStruct":471,"startDateStruct":473,"completionDateStruct":475,"leadSponsor":477,"locationsCount":51},"100493968","neurostimulation-versus-therapy-for-problems-with-emotions-100493968","NCT05712057","Neurostimulation Versus Therapy for Problems With Emotions","Neurostimulation Enhanced Cognitive Restructuring for Transdiagnostic Emotional Dysregulation: A Component Analysis","Inclusion Criteria:\n\n* age 18 to 55\n* elevated overall score on Difficulties with Emotion Regulation Scale (DERS total score \\>=90)\n* has been in the same type of psychotherapy (including none) for the last 4 weeks\u002F1mo (\\*except for current CBT) and is willing to stay on the same regimen throughout the study.\n* low self-reported use of cognitive restructuring (ERQ restructuring subscale average score \\\u003C 4.7)\n* meets criteria for at least one mood (including Bipolar II w\u002Fo current hypomania), anxiety, stressor, OCD, Impulse Control, ADHD, or eating DSM-5 disorder (except exclusionary diagnoses such as severe anorexia). Note: Both current or partial remission of the disorder will be ok for inclusion into the study.\n* verbal agreement to maintain dose of prescribed psychotropic medication (if any) constant throughout the study, provided they are stable on it for the past 4 weeks (except exclusion medication and except if there is a medical emergency requiring changes in medication).\n* Naïve to rTMS\n\nExclusion Criteria:\n\n* current hypomania (Note: Bipolar II w\u002Fo current hypomanic episode is ok for inclusion)\n* meets diagnostic criteria for current or history of psychotic disorder, or psychotic features,\n* meets diagnostic criteria for Bipolar I disorder\n* meets diagnostic criteria on SCID5 for current alcohol or substance use disorder (moderate and high severity) or meets past history of severe alcohol use disorder\n* unable to read, blind, or deaf, or unwilling to give consent\n* non-English speaker,\n* verbal IQ \\\u003C 90 on the North American Adult Reading Test (NART).\n* current uncontrolled anorexia or other condition requiring hospitalization\n* high risk for suicide defined as either having attempted suicide in past 6 months or reporting current suicidal ideation that includes a method, plan, or intent to die\n* current serious medical illness, including current severe migraine headaches\n* started\u002Fchanged psychotropic medications in the prior 4 weeks, or plans to change medication during the study\n* history of seizure except those therapeutically induced by ECT (childhood febrile seizures are acceptable and these subjects may be included in the study), history of epilepsy in self or first degree relatives, stroke, brain surgery, head injury, cranial metal implants, known structural brain lesions that are contraindications for TMS, devices that may be affected by TMS (pacemaker, medication pump, cochlear implant, implanted brain stimulator), have left elbow\u002Fhand\u002Fwrist tendonitis\n* conditions associated with increased intracranial pressure, space occupying brain lesion (considered significant and unsafe for TMS by the study MD), transient ischemic attack, cerebral aneurysm, dementia, Parkinson's or Huntington's disease, multiple sclerosis\n* Wellbutrin \\>300mg per day or on daily stimulant\u002FADHD medications above the recommended FDA daily recommendations\n* use of investigational drug or devices within 4 weeks of screening\n* cochlear implants\n* Pregnancy\n* metal in body that would exclude them from the MRI scan; severe claustrophobia\n* is a prisoner or in police custody at time of screening, or has pending court case jeopardizing the participation in the study\n* has had TMS in their lifetime\n* has had CBT in the past 4 weeks or plans to start therapy during the study\n* weighs over 300 pounds (could not fit in MRI scanner)","55 Years",{"count":422,"type":24},[27],"The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (dlPFC). The secondary aim is to identify key changes in the emotion regulation neural network following the combined intervention versus each of the components alone. The third aim is to explore personalized biomarkers for response to emotion regulation training.\n\nParticipants will undergo brain imaging while engaging in an emotional regulation task. Participants will be randomly assigned to learn one of two emotion regulation skills. Participants will be reminded of recent stressors and will undergo different types of neurostimulation, targeted using fMRI (functional MRI) results. Participants who may practice their emotion regulation skills during neurostimulation in a one-time session. Following this training, participants will undergo another fMRI and an exit interview to assess for immediate neural and behavioral changes. Measures of emotion regulation will be assessed at a one week and a one month follow up visit.",[35,448,449,450,451,452,453,454,455,456,457,458,459,460,461],"Mood Disorders","Stress Disorder","Anxiety Disorders","OCD","Impulse Control Disorder","Eating Disorders","Emotional Dysfunction","Emotional Instability","Emotional Distress","Emotional Maladjustment","Emotional Impulsivity","Obsessive-Compulsive Disorder","Emotion Dysregulation","Borderline Personality Disorder",[460,463,464,465,466,467,468,469,470],"Distress Intolerance","Neuromodulation","Neurostimulation","TMS","cognitive restructuring","regulation skills","neuroimaging","Emotion regulation",{"date":472,"type":43},"2026-03-04",{"date":474,"type":43},"2023-05-15",{"date":476,"type":24},"2027-12-01",{"name":478,"class":50},"Duke University",{"id":480,"slug":481,"hasResults":12,"nctId":482,"briefTitle":483,"officialTitle":484,"acronym":4,"eligibilityCriteria":485,"healthyVolunteers":12,"sex":19,"minAge":129,"maxAge":4,"enrollmentInfo":486,"targetDuration":4,"studyType":25,"phases":488,"briefSummary":489,"conditions":490,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":493,"lastUpdatePostDateStruct":494,"startDateStruct":496,"completionDateStruct":498,"leadSponsor":500,"locationsCount":51},"100494747","assessment-of-emotion-regulation-strategies-used-when-suicidal-100494747","NCT05722197","Assessment of Emotion Regulation Strategies Used When Suicidal","Real-Time Assessment of Emotion Regulation Strategies Used by Suicidal Military Personnel","Inclusion Criteria:\n\n* Currently serving in any Branch or Component of the U.S. military\n* \\>18 years old;\n* Score ≥ 5 on the Scale for Suicidal Ideation and\u002For endorse a suicide attempt, aborted attempt, or interrupted attempt within the past month on the Self-Injurious Thoughts and Behaviors Interview-Revised (SITBI-R)\n* Ability and willingness to complete research-related activities remotely\n* Regular access to an Android or Apple smartphone that is compatible with the ecological momentary assessment application\n\nExclusion Criteria:\n\n* Engagement in mental health treatment within the past year (including taking psychotropic medications)\n* A psychiatric or medical condition that preventing providing informed consent or from participating in the treatments (e.g., psychosis, mania, acute intoxication); or - Expecting to separate from the military within 90 days",{"count":487,"type":24},334,[27],"Crisis Response Planning is an efficacious, one-session intervention that increases positive affect, decreases negative affect and psychiatric hospitalizations, and reduces suicide attempts by 76% among Servicemembers. Crisis Response Planning is hypothesized to reduce suicidality by identifying a variety of personalized strategies that are designed to strengthen and\u002For promote emotion regulation processes.Research in nonmilitary samples suggests the effectiveness of emotion regulation strategies varies across situations. The applicability of these findings to suicidality among Servicemembers is unknown. Improved understanding of what strategies work under which circumstances and for whom will significantly advance our ability to prevent suicide among Servicemembers. Hypotheses include:\n\n1. Use of self-management strategies, thinking about reasons for living, and seeking social support at time t will be associated with significant reductions in suicidal ideation at time t+1.\n2. Use of distraction, reappraisal, and interpersonal emotion regulation strategies at time t will be associated with significant reductions in suicidal ideation at time t+1.\n3. Affect intensity and social context will significantly moderate the time-lagged effects of Crisis Response Planning and emotion regulation strategy use on suicidal ideation.\n4. Distinct profiles of demographic (e.g., gender, age), historical (e.g., prior suicide attempts), and psychological characteristics (e.g., emotion dysregulation, symptom severity) will predict who experiences a decrease in suicidal ideation following the use of Crisis Response Planning and emotion regulation strategies.\n5. (Exploratory): Individuals who utilize their Crisis Response Planning more frequently and perceive Crisis Response Planning as more effective will be more likely to engage in mental health treatment at follow-up.",[491,492,35],"Suicidal Ideation","Treatment Refusal","2026-02-16",{"date":495,"type":43},"2026-02-19",{"date":497,"type":43},"2022-01-23",{"date":499,"type":24},"2027-01-23",{"name":501,"class":50},"Ohio State University",{"id":503,"slug":504,"hasResults":12,"nctId":505,"briefTitle":506,"officialTitle":507,"acronym":4,"eligibilityCriteria":508,"healthyVolunteers":18,"sex":19,"minAge":509,"maxAge":4,"enrollmentInfo":510,"targetDuration":4,"studyType":25,"phases":512,"briefSummary":513,"conditions":514,"keywords":517,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":521,"lastUpdatePostDateStruct":522,"startDateStruct":524,"completionDateStruct":526,"leadSponsor":528,"locationsCount":51},"100603403","jockey-club-support-project-100603403","NCT07136064","Jockey Club Support Project","Jockey Club Support Project to Enhance Emotion Regulation Skills and Resilience of Cross-Boundary Families: A Randomized Controlled Trial","Inclusion Criteria for Parents:\n\n1. have at least one child between the fifth and twelfth grade;\n2. can participate in the intervention with their child;\n3. are Hong Kong residents or have a family member who is a Hong Kong resident;\n4. live in Shenzhen.\n\nInclusion Criteria for Children:\n\n1. are between the fifth and twelfth grade;\n2. are Hong Kong residents or have a family member who is a Hong Kong resident;\n3. live in Shenzhen.\n\nExclusion Criteria:\n\n(a) those who have current diagnoses of severe physical or mental illnesses;","10 Years",{"count":511,"type":24},450,[27],"Guided by the process model of emotion regulation, integrative affect-regulation framework for resilience, and the reciprocal dynamics of emotion, affect, and resilience in the family system, researchers will develop a parallel intervention to incorporate two key members in Mainland-Hong Kong cross-boundary families: a parent and a child by improving their affect\u002Femotion regulation skills, de-escalate family conflicts, and flourish under hardships. Specifically, researchers predict that participants in the intervention group will report greater improvement in resilience, emotion regulation, psychological well-being, family harmony, and social connectedness than those in the control group.",[515,516,35],"Family Relations","Resilience",[518,519,241,520],"cross-boundary families","resilience","randomized controlled trial","2026-02-10",{"date":523,"type":43},"2026-02-12",{"date":525,"type":43},"2025-11-15",{"date":527,"type":24},"2028-08",{"name":529,"class":50},"City University of Hong Kong",{"id":531,"slug":532,"hasResults":12,"nctId":533,"briefTitle":534,"officialTitle":535,"acronym":536,"eligibilityCriteria":537,"healthyVolunteers":12,"sex":19,"minAge":129,"maxAge":4,"enrollmentInfo":538,"targetDuration":4,"studyType":25,"phases":539,"briefSummary":540,"conditions":541,"keywords":542,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":548,"lastUpdatePostDateStruct":549,"startDateStruct":551,"completionDateStruct":553,"leadSponsor":555,"locationsCount":176},"100600334","improving-emotional-wellbeing-of-university-students-emotion-regulation-100600334","NCT07096141","Improving Emotional Wellbeing of University Students: Emotion Regulation","Improving Emotional Wellbeing of University Students Using Culturally Adapted Dialectic Behaviour Approaches in Group Settings\" (UniWELL-D): Protocol of a Feasibility and Effectiveness Study","UniWELL-D","Inclusion Criteria:\n\n1. Must be a Bogazici University student.\n2. Must be 18 years or older.\n3. Must score above the threshold on the Difficulties in Emotion Regulation Scale (DERS-16).\n\nExclusion Criteria:\n\n1. Not Bogazici University student.\n2. Has serious and severe mental illness.\n3. High risk of self-harm\u002Fharm to others.\n4. Scoring below the threshold of on the Difficulties in Emotion Regulation Scale (DERS-16).\n5. Younger than 18 years old.",{"count":131,"type":24},[27],"University students' psychological well-being is a growing public health concern. University life involves major psychological, social, and academic changes, increasing vulnerability to mental health issues. Group-based Dialectical Behaviour Therapy (DBT) has been shown to support student well-being effectively. However, interventions tailored to specific cultural and contextual needs are more likely to be helpful. Western-based therapy models may not fully align with non-Western populations, such as students in Türkiye.\n\nIn Türkiye, public mental health services are often limited to short psychiatric consultations, while therapy is typically accessed privately. University counselling centres offering free or low-cost therapy are therefore essential. Cost-effective interventions like group DBT may be especially valuable in these settings. To address this gap, culturally adapted DBT groups should be developed and evaluated for Turkish university students.\n\nThis study is part of the UniWELL Project (sister to UniWELL-C) and examines the effectiveness of DBT-informed emotion regulation groups for Turkish students. Any Bogazici University student aged 18+ is eligible. Exclusion criteria include severe mental illness, high risk of harm to self\u002Fothers, or scoring below threshold on the Difficulties in Emotion Regulation Scale (DERS-16), as these students may require more individual support.\n\nThe study includes participation in an 8-session DBT-informed group. Participants are expected to benefit from free psychological support, guided reflection, and shared experiences with peers. The research will also contribute to the evidence base for culturally adapted interventions.\n\nThere are some risks: participants may feel overwhelmed during the sessions or while completing questionnaires. If so, support will be provided by a clinical psychology master's student and\u002For the group facilitator, under supervision of an experienced clinical psychologist. If a participant's risk increases, they will be referred to psychiatric services. An emergency contact will be requested to ensure safety if needed.\n\nThe study will take place at Bogazici University through the Translational Clinical Psychology Lab, in collaboration with BUREM. It is expected to run for at least one year, possibly extending up to three years. The study is partially funded by the Bogazici Scientific Research Projects Unit (20022). Dr Ayse Akan (t-clinpsylab@bogazici.edu.tr) is the study lead and main contact.",[35],[241,543,544,545,546,547],"mental health","DBT","group therapy","university student mental health","culturally adapted psychotherapy","2025-12-14",{"date":550,"type":43},"2025-12-22",{"date":552,"type":43},"2025-03-05",{"date":554,"type":24},"2027-12-31",{"name":556,"class":50},"Bogazici University",{"id":558,"slug":559,"hasResults":12,"nctId":560,"briefTitle":561,"officialTitle":562,"acronym":563,"eligibilityCriteria":564,"healthyVolunteers":18,"sex":19,"minAge":129,"maxAge":4,"enrollmentInfo":565,"targetDuration":4,"studyType":25,"phases":567,"briefSummary":568,"conditions":569,"keywords":576,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":584,"lastUpdatePostDateStruct":585,"startDateStruct":587,"completionDateStruct":589,"leadSponsor":591,"locationsCount":51},"100600344","get-better-together-relationship-education-for-military-couples-100600344","NCT07096271","Get Better Together: Relationship Education For Military Couples","Better Together: A Relationship Enrichment Program Targeting Transdiagnostic Interpersonal Emotion Regulation Among Military Couples","GBT RCT","Inclusion Criteria:\n\n* Couple is in a committed romantic relationship of at least six months\n* At least one partner is a military Service member on active duty\n* Both partners are age 18 or older\n* Couple has not previously attended a relationship enrichment retreat or workshop together (e.g., CREDO, Strong Bonds, BSRT). This does not include couples therapy or pre-marital counseling.\n\nExclusion Criteria:\n\n* One or both partners decline to provide informed consent\n* Required command endorsement for retreat attendance is not received (for Service members E-6 and below)\n* Couple is unable or unwilling to attend any of the scheduled retreats during the study period",{"count":566,"type":24},1000,[27],"This study is testing a program called Get Better Together, a relationship education program designed to help military couples effectively navigate life stressors as a team. The goal is to find out if attending Get Better Together improves mental health and relationship skills, and reduces problems like alcohol misuse, aggression, and suicide risk. Couples who join the study will be randomly placed into one of two groups. One group will attend Get Better Together at a weekend retreat. The other group will continue their usual activities and later receive access to an online relationship education program. All participants will complete surveys before the retreat and again 2, 4, and 6 months later.",[35,570,571,572,573,574,575],"Relationship Conflict","Suicide Risk","Alcohol Use","Intimate Partner Violence (IPV)","Relationship Distress","Interpersonal Emotion Regulation",[577,578,579,580,581,241,582,583],"Behavioral: Get Better Together (GBT)","military","intimate relationships","suicide prevention","primary prevention","relationship education","interpersonal emotion regulation","2025-10-15",{"date":586,"type":43},"2025-10-20",{"date":588,"type":43},"2025-09-22",{"date":590,"type":24},"2028-07",{"name":592,"class":50},"Henry M. Jackson Foundation for the Advancement of Military Medicine",{"id":594,"slug":595,"hasResults":12,"nctId":596,"briefTitle":597,"officialTitle":598,"acronym":4,"eligibilityCriteria":599,"healthyVolunteers":18,"sex":19,"minAge":102,"maxAge":600,"enrollmentInfo":601,"targetDuration":4,"studyType":25,"phases":603,"briefSummary":604,"conditions":605,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":606,"lastUpdatePostDateStruct":607,"startDateStruct":609,"completionDateStruct":611,"leadSponsor":613,"locationsCount":51},"100534491","joypop-mobile-mental-health-app-with-youth-100534491","NCT06239519","JoyPop Mobile Mental Health App With Youth","Increasing Access to Mental Health Support for 12-17 Year Old Youth With the JoyPop Mobile Mental Health App: Randomized Controlled Trial","Inclusion Criteria:\n\n* Youth must be on the wait-list for mental health services at St. Joseph's Care Group or Thunder Bay Counselling Centre and be between 12-17 years old.\n* Eligible youth will also need to be available to attend a virtual or in-person orientation session.\n* In order to download the JoyPop app, participants will need access to an iOS device (e.g., iPhone, iPad). Refurbished iPhones containing just the JoyPop app will be provided to participants to use for the duration of the trial if they do not have access to their own.","17 Years",{"count":602,"type":24},110,[27],"Youth in Canada are in need of novel, innovative approaches to support their mental health and wellbeing. Within this age group, research suggests rates of several mental health difficulties and related hospitalizations have increased over recent decades. These challenges are exacerbated in rural communities, such as in Northwestern Ontario, where youth access mental health services less frequently and face longer wait times than those in more urban areas. Such limited access and extended waits can exacerbate symptoms, prolong distress, and increase the risk for adverse outcomes. In partnership with St. Joseph Care Group and Thunder Bay Counselling Centre, the investigators are evaluating the impact of a mental health app (JoyPop) as a tool for youth waiting for mental health services. The JoyPop app was developed to support improved emotion regulation - a fundamental difficulty for youth presenting with mental health challenges and an ability still undergoing maturation during this developmental period. A two-arm randomized controlled trial (RCT) will be used to evaluate the effectiveness of the app compared to usual practice while youth aged 12-17 are waiting for mental health services.",[35,34,30,237],"2025-09-03",{"date":608,"type":43},"2025-09-10",{"date":610,"type":43},"2024-02-01",{"date":612,"type":24},"2025-12",{"name":614,"class":50},"Lakehead University",{"id":616,"slug":617,"hasResults":12,"nctId":618,"briefTitle":619,"officialTitle":620,"acronym":4,"eligibilityCriteria":621,"healthyVolunteers":18,"sex":19,"minAge":129,"maxAge":622,"enrollmentInfo":623,"targetDuration":4,"studyType":25,"phases":624,"briefSummary":625,"conditions":626,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":606,"lastUpdatePostDateStruct":627,"startDateStruct":628,"completionDateStruct":629,"leadSponsor":630,"locationsCount":51},"100534493","joypop-mobile-mental-health-app-with-transitional-aged-youth-100534493","NCT06239545","JoyPop Mobile Mental Health App With Transitional-Aged Youth","Increasing Access to Mental Health Support for 18-25 Year Old Youth With the JoyPop Mobile Mental Health App: Randomized Controlled Trial","Inclusion Criteria:\n\n* Youth must be on the wait-list for mental health services at St. Joseph's Care Group or Thunder Bay Counselling Centre and be between 18-25 years old.\n* Eligible youth will also need to be available to attend a virtual or in-person orientation session.\n* In order to download the JoyPop app, participants will need access to an iOS device (e.g., iPhone, iPad). Refurbished iPhones containing just the JoyPop app will be provided to participants to use for the duration of the trial if they do not have access to their own.","25 Years",{"count":602,"type":24},[27],"New challenges, stressors, and a loss of support often accompany the transition from adolescence to adulthood. Not surprisingly, transitional-aged youth (TAY) between the ages of 18-25 experience some of the highest rates of mental distress. However, access to mental health services diminish for TAY due to gaps in care when transitioning from pediatric to adult services. These challenges are exacerbated in rural communities, such as in Northwestern Ontario, where youth already access mental health services less frequently and face longer wait times than those in more urban areas. Limited access and extended waits can exacerbate symptoms, prolong distress, and increase the risk for adverse outcomes. Novel, innovative approaches are urgently needed to support TAY in Northwestern Ontario. In partnership with St. Joseph Care Group and Thunder Bay Counselling Centre, the investigators are evaluating the impact of a mental health app (JoyPop) as a tool for TAY waiting for mental health services. The JoyPop app was developed to support improved emotion regulation - a fundamental difficulty for youth presenting with mental health challenges. A two-arm randomized controlled trial (RCT) will be used to evaluate the effectiveness of the app compared to usual practice while TAY are waiting for mental health services.",[35,34,30,237],{"date":608,"type":43},{"date":610,"type":43},{"date":612,"type":24},{"name":614,"class":50},{"id":632,"slug":633,"hasResults":12,"nctId":634,"briefTitle":635,"officialTitle":636,"acronym":4,"eligibilityCriteria":637,"healthyVolunteers":18,"sex":19,"minAge":129,"maxAge":622,"enrollmentInfo":638,"targetDuration":4,"studyType":25,"phases":639,"briefSummary":640,"conditions":641,"keywords":642,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":606,"lastUpdatePostDateStruct":651,"startDateStruct":653,"completionDateStruct":655,"leadSponsor":657,"locationsCount":51},"100515411","joypop-mobile-mental-health-app-with-indigenous-transitional-aged-youth-100515411","NCT05991154","JoyPop Mobile Mental Health App With Indigenous Transitional-Aged Youth","Increasing Access to Mental Health Support for 18-25 Year Old Indigenous Youth With the JoyPop Mobile Mental Health App: Randomized Controlled Trial","Inclusion Criteria:\n\n* Indigenous transitional-aged youth must be on the wait-list for mental health services at Dilico Anishinabek Family Care and be between 18-25 years old.\n* Eligible youth will also need to be available to attend a virtual or in-person orientation session.\n* In order to download the JoyPop app, participants will need access to an iOS device (e.g., iPhone, iPad). Refurbished iPhones containing just the JoyPop app will be provided to participants to use for the duration of the trial if they do not have access to their own.",{"count":602,"type":24},[27],"Indigenous youth in Northwestern Ontario who need mental health supports experience longer waits than non-Indigenous youth within the region and when compared to youth in other more urban areas. Limited access and extended waits can exacerbate symptoms, prolong distress, and increase risk for more serious outcomes. Transitional aged youth (i.e., those in their mid-late teens to early twenties) are a particularly vulnerable group. Novel, innovative approaches are urgently needed to provide support for Indigenous youth in Northwestern Ontario. In partnership with Dilico Anishinabek Family Care, the investigators are evaluating the impact of a mental health app (JoyPop) as a tool for Indigenous transitional-aged youth who are waiting for mental health services. The JoyPop app was developed to support improved emotion regulation - a key difficulty for youth presenting with mental health challenges. A two-arm randomized controlled trial (RCT) will be used to evaluate the effectiveness of the app compared to usual practice while Indigenous transitional-aged youth are waiting for mental health services.",[35,34,30,237],[643,644,645,241,646,647,543,648,649,650],"eHealth","mobile health","smartphone","Indigenous","First Nations","youth","transitional-aged youth","waitlist",{"date":652,"type":43},"2025-09-05",{"date":654,"type":43},"2023-08-11",{"date":656,"type":24},"2025-12-31",{"name":614,"class":50},{"id":659,"slug":660,"hasResults":12,"nctId":661,"briefTitle":662,"officialTitle":663,"acronym":4,"eligibilityCriteria":664,"healthyVolunteers":12,"sex":19,"minAge":204,"maxAge":129,"enrollmentInfo":665,"targetDuration":4,"studyType":25,"phases":667,"briefSummary":668,"conditions":669,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":672,"lastUpdatePostDateStruct":673,"startDateStruct":675,"completionDateStruct":677,"leadSponsor":678,"locationsCount":176},"100503818","lh-canine-therapy-study-100503818","NCT05840198","LH Canine Therapy Study","Evaluating the Impact of a Canine-assisted Therapy Program in Youth Residing in a Residential Treatment Center.","Inclusion Criteria:\n\n* Youth must be receiving in-patient services at Lawrence Hall or Lydia Home\n* Youth must provide informed assent.\n* Youth must complete at least one of the primary outcomes during the baseline assessment.\n* Youth must remain in residential care for the duration of the 6-week intervention.\n* Youth assigned to the Recovery \\& Care intervention group must attend at least one of the 6 sessions.\n\nExclusion Criteria:\n\n* Severe cognitive, psychiatric, or physical condition or limitation that would prevent participation.\n* Severe animal allergy\n* Animal phobia\n* History of mistreatment of animals.",{"count":666,"type":24},48,[27],"The goal of this pilot project is to test for initial efficacy of the Recovery \\& Care Canine-Assisted Therapy program that has been developed and implemented in youth institutionalized for behavioral and emotional problems. We are using two study sites, Lawrence Hall and Lydia Home, both Chicago-based residential treatment centers for youth with behavioral and emotional problems, many of whom have experienced child maltreatment and trauma. Comparisons will be made to a matched sample of youth from Lawrence Hall and Lydia Home receiving treatment as usual. Results from this project will provide preliminary evidence of whether a structured, goal-oriented intervention program focused on dog training activities has direct impact on increasing youth emotional self-regulation, impulse control, and self-efficacy, which are important targets for intervention among youth with mental health problems. If successful, this project could lead to a larger, randomized control clinical trials study that tests the longitudinal impact of the program that could further lead to national dissemination of the Recovery \\& Care curriculum as an alternative therapeutic approach.",[35,670,671],"Behavioral Disorder","Self Esteem","2025-08-15",{"date":674,"type":43},"2025-08-17",{"date":676,"type":43},"2023-05-24",{"date":612,"type":24},{"name":679,"class":50},"University of Chicago",{"id":681,"slug":682,"hasResults":12,"nctId":683,"briefTitle":684,"officialTitle":685,"acronym":4,"eligibilityCriteria":686,"healthyVolunteers":12,"sex":19,"minAge":204,"maxAge":600,"enrollmentInfo":687,"targetDuration":4,"studyType":25,"phases":688,"briefSummary":689,"conditions":690,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":672,"lastUpdatePostDateStruct":691,"startDateStruct":693,"completionDateStruct":695,"leadSponsor":696,"locationsCount":51},"100499863","feasibility-of-a-dog-training-therapy-program-in-uc-outpatient-youth-receiving-psychiatric-services-100499863","NCT05788783","Feasibility of a Dog Training Therapy Program in UC Outpatient Youth Receiving Psychiatric Services","Evaluating the Impact of a Canine-assisted Therapy Program in Youth Enrolled in Outpatient Treatment for Social, Emotional, and Behavioral Problems.","Inclusion Criteria:\n\n* Currently receiving outpatient mental health services at the University of Chicago or have received outpatient mental health services from the community in the last 12 months.\n* Available for scheduling during the entire 6-week intervention program\n* Interest in participating in the program\n\nExclusion Criteria:\n\n* Severe cognitive, psychiatric, or physical condition or limitation that would prevent participation.\n* Severe animal allergy\n* Animal phobia\n* History of mistreatment of animals.\n* Above-average scores on both measures of behavioral regulation and emotional regulation\n* WASI t-score of intellectual ability \\\u003C 60.",{"count":666,"type":24},[27],"The goal of this pilot project is to test for initial efficacy of the Recovery \\& Care Canine-Assisted Therapy program that has been developed and implemented in Lawrence Hall, a Chicago-based residential treatment center for maltreated youth. In this study, the investigators test the feasibility, acceptability, and short-term efficacy of expanding the program to a group of youth currently in outpatient treatment for social, emotional, and behavioral problems. Results from this project will provide preliminary evidence of whether a structured, goal-oriented intervention program focused on dog training activities has direct impact on increasing youth emotional self-regulation, impulse control, and self-efficacy, which are important targets for intervention among youth with mental health problems. If successful, this project could lead to a larger, randomized control clinical trials study that tests the longitudinal impact of the program that could further lead to national dissemination of the Recovery \\& Care curriculum as an alternative therapeutic approach.",[35,670,671],{"date":692,"type":43},"2025-08-21",{"date":694,"type":43},"2024-02-26",{"date":612,"type":24},{"name":679,"class":50},{"id":698,"slug":699,"hasResults":12,"nctId":700,"briefTitle":701,"officialTitle":702,"acronym":703,"eligibilityCriteria":704,"healthyVolunteers":12,"sex":19,"minAge":705,"maxAge":329,"enrollmentInfo":706,"targetDuration":4,"studyType":25,"phases":707,"briefSummary":708,"conditions":709,"keywords":712,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":717,"lastUpdatePostDateStruct":718,"startDateStruct":720,"completionDateStruct":722,"leadSponsor":724,"locationsCount":51},"100600704","comparing-brief-psychoanalytic-couple-therapy-and-emotionally-focused-therapy-in-reducing-relationship-distress-100600704","NCT07100951","Comparing Brief Psychoanalytic Couple Therapy and Emotionally Focused Therapy in Reducing Relationship Distress","Comparing the Efficacy of Brief Psychoanalytic Couple Therapy and Emotionally Focused Therapy in Reducing Relationship Distress and Psychopathological Symptoms: A Randomized Controlled Trial","BPCT-EFT-RCT","Inclusion Criteria:\n\n* Heterosexual couples (both partners must participate)\n* Age between 24 and 65 years\n* Minimum 2 years of relationship duration\n* At least one partner scoring ≤ 30 on the Dyadic Adjustment Scale (DAS-32), indicating clinically significant relationship distress\n* At least one partner scoring in the mild, moderate, or severe range on the Beck Depression Inventory-II (BDI-II) or Beck Anxiety Inventory (BAI)\n\nExclusion Criteria:\n\n* Current participation in individual or couple psychotherapy\n* Use of psychiatric medication during the past 3 months\n* Presence of severe psychiatric disorders (e.g., psychosis, bipolar disorder)\n* History or presence of physical or severe psychological partner violence, assessed via Conflict Tactics Scale (CTS-2)\n* Active substance use disorder within the past 6 months","24 Years",{"count":105,"type":24},[27],"This study compares the effects of two different couple therapy approaches-Brief Psychoanalytic Couple Therapy (BPCT) and Emotionally Focused Therapy (EFT)-on reducing relationship problems and emotional symptoms like depression and anxiety.\n\nMany couples struggle with emotional distance, repeated arguments, and dissatisfaction in their relationships. While EFT is a widely used and research-supported therapy that focuses on rebuilding emotional bonds, BPCT is a less-studied method that aims to help couples understand how early relationship experiences and unconscious patterns affect their current interactions.\n\nThe purpose of this study is to find out whether one of these therapies is more effective than the other in improving relationship satisfaction and reducing emotional distress. The study also looks at changes in how people regulate their emotions and how secure they feel in their relationships after therapy.\n\nIn this randomized controlled trial, 60 heterosexual couples experiencing relationship distress and symptoms of anxiety or depression will be randomly assigned to one of three groups:\n\nBPCT group - couples receive weekly online therapy focusing on deep emotional and psychological patterns in their relationship.\n\nEFT group - couples receive weekly online therapy focusing on emotional connection and improving communication.\n\nWaitlist control group - couples do not receive therapy during the study but will be offered therapy afterward.\n\nEach therapy lasts 12 weeks, and follow-up assessments will be conducted up to 6 months after therapy ends. Data will be collected before, during, and after treatment using questionnaires that measure relationship satisfaction, depression, anxiety, emotional regulation, and attachment style.\n\nThe results of this study will help determine which type of therapy is more beneficial for couples experiencing emotional and relational difficulties and may provide important insights for mental health professionals working with distressed couples.",[710,450,35,711,574],"Depressive Disorder","Attachment",[713,714,715,716,574,35,34,30],"Brief Psychoanalytic Couple Therapy","Emotionally Focused Therapy","Couple Therapy","Online Psychotherapy","2025-07-28",{"date":719,"type":43},"2025-08-03",{"date":721,"type":43},"2025-07-01",{"date":723,"type":24},"2026-07-15",{"name":725,"class":50},"Beykoz University"]