[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"emotional-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:emotional-disorder":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,46,76,108,131,164,192,219],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100603584","compassion-based-family-intervention-for-adolescents-100603584",false,"NCT07138417","Compassion-Based Family Intervention for Adolescents","Compassion-Based Family Intervention for Adolescents With Emotional Disorders and Their Parents: A Randomized Waitlist-Controlled Trial","Inclusion Criteria:\n\n* the adolescent is aged 12-18 years\n* for the adolescent, required scores at enrollment: at least one of the following criteria is met (i) 17-item Hamilton Depression Rating Scale (HAMD-17) (Hamilton, 1960) total score ≥17 and ≤30, (ii) Hamilton Anxiety Rating Scale (HAMA) (Hamilton, 1959) total score ≥18 and ≤29; and in addition, the item 3 score of HAMD-17 (suicide) must be ≤2\n* at least one parent is willing to participate\n* the adolescent has normal auditory and visual perception abilities and intellectual level\n* the participating parent has normal reading and writing ability\n* the adolescent has no history of manic episodes\n\nExclusion Criteria:\n\n* the adolescent presents with psychotic symptoms, bipolar disorder, or schizophrenia\n* the parent suffers from a mental illness or psychological disorder\n* the adolescent or their parent has a history of substance abuse\n* the adolescent or their parent has a severe neurological disorder or major physical disease\n* the adolescent or their parent is assessed as having high suicide risk","ALL","12 Years","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Adolescents with emotional disorders (such as depression or anxiety) often experience distress that also affects their parents, creating a cycle of stress within the family. This study tests a new compassion-based family intervention designed to help both adolescents and their parents. The program includes six weekly sessions (120 minutes each). The study will recruit 60 parent-adolescent dyads. Half will receive the intervention immediately; the other half will wait 6 weeks before receiving it. We will measure changes in depression, anxiety, parenting stress, family relationships, and - using brain imaging (fNIRS) and heart rate monitors - how the intervention affects parent-child emotional and physiological synchrony. Assessments will take place before the intervention, right after, and at 3-month and 6-month follow-ups. The goal is to see whether this family-focused compassion program can improve mental health for both adolescents and their parents.",[27],"Emotional Disorder",[29,30,31,32],"Emotional disorder","adolescents","compassion","parents","RECRUITING","2026-05-05",{"date":36,"type":37},"2026-05-08","ACTUAL",{"date":39,"type":37},"2025-08-30",{"date":41,"type":21},"2027-07",{"name":43,"class":44},"Beijing HuiLongGuan Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":45},"100635771","unified-protocol-for-emotional-disorders-hitop-pro-trial-100635771","NCT07557017","Unified Protocol for Emotional Disorders: HiTOP-PRO Trial","Investigating the Impact of the Unified Protocol on HiTOP Dimensions and Temperamental Traits in Patients With Emotional Disorders","UP-HITOP","Inclusion Criteria: Adults aged 18-65 years.\n\nSeeking outpatient treatment at NÚDZ for emotional disorder symptoms.\n\nMeets diagnostic eligibility on ADIS-5 for at least one of the following (ICD-10 categories consistent with the protocol): F32, F33, F34, F40, F41, F42, F43, F45, F60, F61.\n\nAble to understand and complete study questionnaires and procedures (Czech language).\n\nWilling and able to participate in psychotherapy and complete assessments at baseline and post-treatment (14 weeks).\n\nIf taking psychotropic medication: dose stable for ≥6 weeks prior to enrolment and expected to remain stable during the acute study period where clinically feasible.\n\nProvides written informed consent.\n\nExclusion Criteria: Current or lifetime psychotic disorder or current manic\u002Fhypomanic episode.\n\nHigh acute suicide risk requiring a higher level of care (e.g., imminent risk, recent serious attempt) or current severe self-harm risk incompatible with outpatient psychotherapy study procedures.\n\nPrimary substance use disorder requiring specialised treatment or acute intoxication\u002Fwithdrawal.\n\nSevere cognitive impairment or neurodevelopmental\u002Fneurological condition that prevents valid consent or completion of study procedures.\n\nConcurrent psychological treatment that would conflict with study participation (e.g., starting a new structured psychotherapy during the 14-week study period), unless it constitutes the assigned TAU.\n\nImmediate need for intensive treatment (e.g., inpatient admission) at the time of screening.\n\nInability to commit to the study schedule or complete required assessments.",{"count":55,"type":21},90,[24],"This randomised, parallel-group clinical trial evaluates the effects of the Unified Protocol (UP), a transdiagnostic cognitive-behavioural psychotherapy, on dimensional symptom outcomes aligned with the Hierarchical Taxonomy of Psychopathology (HiTOP) and on related temperamental\u002Fpersonality traits in adults with emotional disorders. Participants are randomly assigned (1:1:1) to UP, treatment as usual (TAU), or a waitlist (WL). Outcomes are assessed at baseline and after approximately 14 weeks. A planned follow-up assessment approximately 3 months after treatment completion is collected in the UP arm only.",[27],[60,61,62,63,64,65,66],"emotional disorders","unified protocol","HiTOP","Hierarchical Taxonomy Of Psychopathology","transdiagnostic therapy","personality traits","temperamental traits","2026-04-22",{"date":69,"type":37},"2026-04-29",{"date":71,"type":37},"2025-10-08",{"date":73,"type":21},"2028-07-31",{"name":75,"class":44},"National Institute of Mental Health, Czech Republic",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":83,"maxAge":17,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":94,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":45},"100544791","matching-assessment-and-treatment-for-children-with-disruptive-behaviour-and-their-parents-100544791","NCT06373484","Matching Assessment and Treatment for Children With Disruptive Behaviour and Their Parents","MATCH-DB","Inclusion Criteria:\n\n* Child is borderline\u002Fclinically at risk on the Child Behaviour Checklist (CBCL) or Teacher Report Form (TRF) (T-score greater than or equal to 60 on Externalizing Problems composite scale or a T-score greater than or equal to 65 on the Oppositional Defiant Disorder and\u002For Conduct Disorder scales)\n* Child has clinically severe impairment in the interpersonal relations (greater than 3), functioning in schoolwork (greater than 3), or total domains (greater than 15) on the Columbia Impairment scale.\n* Parent is able and willing to participate in a group treatment\n\nExclusion Criteria:\n\n* Child has an ongoing query or diagnosis of Pervasive Developmental Disorder or Autism or Asperger's Disorder\n* Evidence of cognitive delays or an intellectual disability (based on the Kauffman Brief Intelligence Test-2 (KBIT-2), verbal and\u002For IQ composite standard score below 80 or collateral information)\n* Child behaviour or emotional functioning that make group participation not possible\n* Child preference for individual treatment.\n* Parent behaviour or emotional functioning that make group participation not possible\n* Parent preference for individual treatment.","6 Years",{"count":85,"type":21},200,[24],"This study will develop and test whether personalized profiles of children with Disruptive Behaviour Disorder (DBD) and their parents based on important psychological, emotional, and neuropsychological indicators predict their response to child cognitive behavioral treatment and Behavioral Parent Training.",[89,27,90,91,92,93],"Disruptive Behavior Disorder","Behavioural Disorder","Attention Deficit Hyperactivity Disorder","Conduct Disorder","Oppositional Defiant Disorder",[95,96,91,92,93,97,98],"Emotional and Behavioural Disorders","Disruptive Behaviour Disorder","Parenting Skills","Behavioural Parenting Training","2026-03-16",{"date":101,"type":37},"2026-03-17",{"date":103,"type":37},"2022-10-01",{"date":105,"type":21},"2027-09",{"name":107,"class":44},"Centre for Addiction and Mental Health",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":118,"phases":4,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":45},"100617972","impact-of-emotional-disorders-on-response-to-immune-checkpoint-inhibitor-therapy-in-liver-cancer-100617972","NCT07325565","Impact of Emotional Disorders on Response to Immune Checkpoint Inhibitor Therapy in Liver Cancer","Impact of Emotional Disorders on Response to Immune Checkpoint Inhibitor Therapy in Liver Cancer: A Multicenter, Prospective, Multi-Cohort Study","Inclusion Criteria:\n\n* Age between 18 and 75 years, inclusive, regardless of gender.\n* Presence of at least one radiologically measurable lesion according to the Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 (defined as a lesion with a longest diameter of ≥10 mm on CT scan).\n* Newly diagnosed, treatment-naïve patients with hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICC).\n* Child-Pugh liver function score ≤ 7.\n* Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.\n* Absence of severe organic diseases affecting the heart, lungs, brain, or other major organs.\n\nExclusion Criteria:\n\n* History of other malignancies.\n* Recurrent HCC.\n* Prior systemic therapy for HCC.\n* Hepatic decompensation.\n* History of severe psychiatric disorders.\n* Current use of antidepressant or anxiolytic medication.\n* Inability to comprehend or complete the assessment questionnaires.","75 Years",{"count":117,"type":21},651,"OBSERVATIONAL","Hepatocellular carcinoma (HCC) carries a poor prognosis, with limited efficacy from current therapies including immune checkpoint inhibitors (ICIs). Concurrently, emotional distress (ED) is highly prevalent in cancer patients and is implicated in tumor progression via neuroendocrine-immune axis dysregulation (e.g., HPA axis activation, immunosuppressive TME). Emerging evidence, particularly from lung cancer, suggests ED may adversely impact ICI efficacy. However, its specific role and clinical significance in HCC, especially regarding ICI response, remain poorly understood.\n\nTo address this gap, we propose a large-scale, prospective, multicenter, multi-cohort study to systematically evaluate the impact of ED on treatment outcomes in HCC patients receiving immunotherapy.",[121,27],"Liver Cancer","2025-12-24",{"date":124,"type":37},"2026-01-08",{"date":126,"type":37},"2025-12-20",{"date":128,"type":21},"2028-12-31",{"name":130,"class":44},"Tongji Hospital",{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":138,"targetDuration":4,"studyType":22,"phases":140,"briefSummary":141,"conditions":142,"keywords":146,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":45},"100598364","unified-protocol-in-penitentiary-facilities-100598364","NCT07070531","Unified Protocol in Penitentiary Facilities","Feasibility and Clinical Utility Study of the Unified Protocol for Group Treatment of Emotional Disorders in Penitentiary Facilities","Inclusion Criteria:\n\n* At least one emotional disorder diagnosis (e.g., anxiety, depression, OCD, trauma-related, somatic, dissociative) based on the MINI interview\n* Comprehension of the intervention language (Spanish or Catalan)\n* Substance abstinence for more than 1 month\n* Voluntary participation and availability for all assessment and treatment sessions\n* Stable pharmacological treatment during the study unless medically contraindicated\n* Signed informed consent\n\nExclusion Criteria:\n\n* No emotional disorder diagnosis\n* Cognitive impairment or IQ \\\u003C70 preventing comprehension\n* Diagnosis of a mental disorder incompatible with group formats (e.g., histrionic personality disorder)\n* Suicide risk at assessment\n* Legal status involving potential release or leave that could affect adherence",{"count":139,"type":21},25,[24],"Emotional disorders (EDs), which include anxiety disorders, unipolar mood disorders, and other related conditions, exhibit a high prevalence within prison populations, significantly exceeding that of the general population. Despite the high incidence of these disorders, the resources available for their treatment in correctional facilities are limited. The shortage of both human and material resources hinders inmates' access to quality mental health care.\n\nIn this context, the Unified Protocol (UP) for the transdiagnostic treatment of emotional disorders, a transdiagnostic intervention grounded in Cognitive Behavioral Therapy, has demonstrated effectiveness in addressing a variety of psychological problems across different contexts. It has also proven to be cost-effective, particularly when delivered in a group format. Therefore, implementing the UP in group format within correctional settings could represent a viable strategy to optimize limited resources and provide accessible and effective treatment to a larger number of inmates.\n\nThe primary objective of this pilot study is to evaluate the feasibility and clinical utility of the UP for the treatment of emotional disorders in prison environments. To this end, the UP will be delivered to approximately 25 participants, organized into groups of six to eight individuals, each receiving 12 weekly sessions lasting one hour. Follow-up assessments will be conducted at one, three, and six months after the intervention.\n\nA mixed-methods approach will be employed to analyze the results, combining quantitative analyses to assess changes in emotional symptomatology and qualitative analyses to explore participant satisfaction and therapist acceptance. It is expected that participants will experience statistically significant improvements in emotional symptoms and that these improvements will be sustained over time, up to the six-month follow-up. It is also anticipated that participants will report a high level of satisfaction with the treatment. Furthermore, therapists are expected to evaluate the intervention positively and to identify potential barriers to its implementation.\n\nThe results of this pilot study will contribute to improving the feasibility and clinical utility of the UP in correctional settings, while also laying the groundwork for a future randomized controlled trial involving a larger number of facilities, participants, and therapists.",[143,144,145,27],"Depression Disorders","Anxiety","Mood Disorders",[147,148,149,150,151,152,153],"Unified Protocol","Transdiagnostic Intervention","Incarcerated Population","Correctional Facilities","Group Therapy","Cognitive-behavioral Therapy","Emotional Disorders","NOT_YET_RECRUITING","2025-07-16",{"date":157,"type":37},"2025-07-17",{"date":159,"type":21},"2025-11-01",{"date":161,"type":21},"2026-07-01",{"name":163,"class":44},"Instituto de Investigación Sanitaria Aragón",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":168,"acronym":169,"eligibilityCriteria":170,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":171,"enrollmentInfo":172,"targetDuration":4,"studyType":22,"phases":174,"briefSummary":175,"conditions":176,"keywords":178,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":45},"100560479","progression-of-a-group-of-patients-suffering-from-emotional-dysregulation-but-heterogeneous-in-terms-of-diagnosis-benefiting-from-the-dbt-group-programme-100560479","NCT06577675","Progression of a Group of Patients Suffering From Emotional Dysregulation But Heterogeneous in Terms of Diagnosis, Benefiting From the DBT Group Programme.","PEAC-TRE","Inclusion Criteria:\n\n* Patients affiliated to or entitled under a social security scheme\n* Patients aged 18 to 65 suffering from emotional dysregulation and presenting one of the following clinical profiles: borderline disorder, bipolar disorder, addictive disorders, eating disorders, PTSD.\n* Follow-up by the Saint Etienne sector (mobile teams, psychological medical centre, intra-hospital services, full-time therapeutic reception centre and day hospitals).\n* DERS scale score \\> 94.\n* Patient having received informed information about the study and having signed consent to participate in the study.\n\nExclusion Criteria:\n\n* Psychotic disorders,\n* Melancholic depression,\n* Aggressive and hostile behaviour preventing group work,\n* Intellectual deficit,\n* Patient under guardianship.","65 Years",{"count":173,"type":21},32,[24],"Human beings experience emotions and have the ability to manage them, but when these abilities are undermined by mental illness, the result is emotional dysregulation. Borderline patients (1 to 4% of the population) suffer from this symptom and can benefit from a specific therapy: DBT (Dialectical Behaviour Therapy; Linehan, 1993). Created specifically for this condition, DBT significantly reduces emotional dysregulation, a dimension at the root of behavioural disorders that is known to be poorly relieved by drug treatments. The DBT group training programme offers patients the opportunity to learn and practise emotional regulation skills. Four types of skills are taught skills: mindfulness, interpersonal skills, emotional regulation and and distress tolerance. This therapy is part of the psychiatric care, in which patients take responsibility in their own care.\n\nThere are many studies showing the effectiveness of DBT and its programme with borderline patients. But there are other pathologies concerned by emotional dysregulation: thymic disorders in particular bipolar (1 to 2.5%), addictive disorders (8 to 10%), eating disorders (ADD, 10%), post-traumatic stress disorder (PTSD, 2%).",[177,27],"Emotion Regulation",[179,180,181,182],"emotional dysregulation","training programme","behaviour therapy","heterogeneous diagnostic groups","2025-06-19",{"date":185,"type":37},"2025-06-22",{"date":187,"type":37},"2025-04-17",{"date":189,"type":21},"2026-05",{"name":191,"class":44},"Centre Hospitalier Universitaire de Saint Etienne",{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":199,"targetDuration":4,"studyType":22,"phases":200,"briefSummary":201,"conditions":202,"keywords":204,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":218},"100587445","effectiveness-and-acceptability-of-the-unified-protocol-for-the-transdiagnostic-treatment-of-emotional-disorders-in-people-with-long-covid-19-100587445","NCT06928480","Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in People With Long COVID-19.","UP-LONGCOVID-R","Inclusion Criteria:\n\n* Residing in Autonomous Community of Aragon (Spain).\n* Being at least 18 years old.\n* Understanding of Spanish.\n* Being diagnosed with long COVID-19: documented SARS-CoV-2 infection and persistence of symptoms beyond 12 weeks after the acute infection.\n* Symptoms of depression (ODSIS≥7) and\u002For anxiety (OASIS≥8).\n* Meeting the criteria for an emotional disorder diagnosis.\n* Having access to Internet.\n* Signing the informed consent.\n\nExclusion Criteria:\n\n* Pre-existing emotional symptoms prior to the acute SARS-CoV-2 infection.\n* Actually receiving psychological treatment.\n* Having a diagnosis of severe mental disorder (e.g., personality disorder, bipolar disorder, etc.).\n* Active suicidal ideation at the time of the assessment.\n* Individuals on psychotropic medication must maintain their dosage throughout the study, unless medically contraindicated.",{"count":55,"type":21},[24],"This Randomized Controlled Trial (RCT) aims to assess the effectiveness and acceptability of the Unified Protocol (UP) in an online group format for the treatment of emotional disorders in adults. Participants will be 90 adults (45 in the control group and 45 in the experimental group) with diagnosis of long COVID and comorbid emotional disorders. Participants will be recruited at Hospital Royo Villanova from Zaragoza, Spain.\n\nIn this study it will be explored whether the changes obtained after the intervention in emotional disorders and cognitive complaints are maintained over 12 months. Additionally, levels of chronic stress will be longitudinally evaluated in the experimental group through accumulated cortisol levels in hair, before and after the application of the UP.",[203,27,144,143,177],"Long Covid-19",[205,153,206,147,207,208,209],"Long COVID-19","Emotion regulation skills","Transdiagnostic","Psychological","Cognitive Behavioral","2025-05-19",{"date":212,"type":37},"2025-05-22",{"date":214,"type":37},"2025-05-01",{"date":216,"type":21},"2026-12-31",{"name":163,"class":44},2,{"id":220,"slug":221,"hasResults":11,"nctId":222,"briefTitle":223,"officialTitle":224,"acronym":4,"eligibilityCriteria":225,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":226,"targetDuration":4,"studyType":22,"phases":228,"briefSummary":229,"conditions":230,"keywords":233,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":45},"100558156","unified-protocol-for-treatment-of-emotional-disorders-in-brief-groups-in-primary-care-services-in-spain-100558156","NCT06547450","Unified Protocol for Treatment of Emotional Disorders in Brief Groups in Primary Care Services in Spain","Study of the Cost-efficacy and Acceptability of the Unified Protocol for Treatment of Emotional Disorders in Brief Groups in Primary Care Services in Spain (PU-AP)","Inclusion Criteria:\n\n* Have at least one EDs diagnosis (anxiety, depressive, obsessive-compulsive, trauma and somatic disorders) from the ADIS-5 interview\n* Have a score between 0 and 5 severity (mild-moderate) on the diagnoses on the CSR of the ADIS-5\n* Be able to attend all assessment and treatment sessions\n* Individuals on pharmacological treatment will be asked to maintain the dosage for the duration of the study, unless there is a medical contraindication\n\nExclusion Criteria:\n\n* Absence of clinical diagnosis\n* Presenting a diagnosis of EDs with a severity score on diagnoses between 6 and 8 on the ADIS-5 CSR (severe) or a clinical condition requiring specialized mental health intervention such as presence of severe mental disorder (e.g., personality disorder, bipolar disorder, or schizophrenia), suicide risk at the time of assessment, or substance use in the past three months\n* Who have received 8 or more sessions of CBT (during the past five years) with techniques such as cognitive flexibility or exposure\n* Who are receiving psychological treatment.",{"count":227,"type":21},180,[24],"The aim of this project is to contribute to the improvement of psychological care received in primary care (PC), through the study of the cost-effectiveness and acceptability of the Unified Protocol for the treatment of emotional disorders in brief groups in primary care services in Spain (PU-AP) for the treatment of emotional disorders (EDs), the most prevalent in our society. To do so, a pilot study will be carried out, and, subsequently, a randomized clinical trial to study the efficacy, cost-effectiveness and acceptability of the Unified Protocol for the transdiagnostic treatment of EDs, applied in 5 or 8 group sessions. Finally, the researchers will analyze whether there are specific patient profiles that will benefit more from one or the other condition. The results will contribute to the personalization of the psychological treatment of users with EDs attending PC in the Spanish public health system.",[27,231,232],"Anxiety Disorders","Depressive Disorder",[27,147,234,235,236,237],"Primary Care","Transdiagnostic approach","Group format","Brief format","2025-02-27",{"date":240,"type":37},"2025-03-03",{"date":242,"type":21},"2025-05-10",{"date":244,"type":21},"2027-09-01",{"name":163,"class":44}]