[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"emotional-regulation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:emotional-regulation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,50,82,113,148,182,221,253,279,303,328,358,393,419],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100639779","effect-of-yoga-and-values-clarification-on-stress-comfort-and-emotional-regulation-in-parents-of-children-with-special-needs-100639779",false,"NCT07628569","Effect of Yoga and Values Clarification on Stress, Comfort, and Emotional Regulation in Parents of Children With Special Needs","The Effect of a Comfort Theory-Based Yoga and Values Clarification Intervention on Emotion Regulation, Comfort, and Stress Levels in Parents of Children With Special Needs","Inclusion Criteria:\n\n* Being a parent of a child with special needs,\n* Not having received prior yoga training,\n* Not having a physical problem that would prevent them from practicing yoga,\n* Not having communication problems,\n* Speaking Turkish,\n* Not having learning disabilities,\n* Being suitable\u002Fwilling to work in a group.\n\nExclusion Criteria for Parents:\n\n* Having a physical problem that would prevent them from practicing yoga,\n* The parent not being a volunteer,\n* Not demonstrating compatibility with working in a group.",true,"ALL","18 Years",{"count":20,"type":21},66,"ESTIMATED","INTERVENTIONAL",[24],"NA","Parents of children with special needs often experience high levels of stress and difficulties in emotional regulation, which may negatively affect both their well-being and parent-child interactions. This study aims to evaluate the effect of a Comfort Theory-based yoga and values clarification intervention on emotional regulation, comfort, and perceived stress levels in these parents.\n\nThis randomized controlled study will include three groups: a yoga intervention group, a values clarification group, and a control group. Participants will be randomly assigned to groups. Data will be collected using the Emotion Regulation Scale, Perceived Stress Scale, and General Comfort Questionnaire.\n\nThe intervention is expected to improve emotional regulation and comfort levels while reducing perceived stress among parents of children with special needs. The findings may contribute to the development of effective nursing interventions to support caregiver well-being.",[27,28,29],"Stress","Emotional Regulation","Comfort",[31,32,27,33,28,34,35,36],"yoga","Values Clarification","Parents","comfort","Special Needs Children","Nursing Intervention","RECRUITING","2026-06-01",{"date":40,"type":41},"2026-06-05","ACTUAL",{"date":43,"type":41},"2026-04-29",{"date":45,"type":21},"2026-07",{"name":47,"class":48},"Ankara Yildirim Beyazıt University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":16,"sex":57,"minAge":18,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":67,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":78,"leadSponsor":80,"locationsCount":49},"100640077","trauma-informed-yoga-intervention-in-young-women-100640077","NCT07589777","Trauma-Informed Yoga Intervention in Young Women","Trauma-Informed Yoga Intervention: A Randomized Controlled Trial on Psychological Trauma, Emotion Regulation, and Interoceptive Awareness in Young Adult Women","Inclusion Criteria:\n\n* Being a woman aged 18-25 years\n* Providing voluntary written informed consent after being informed about the study\n* Scoring within the highest 25th percentile on the Transmitted Psychological Trauma Scale based on the pre-screening assessment, indicating high levels of trauma-related symptoms\n* Having no physical limitations that would prevent participation in weekly sessions and being medically eligible to engage in yoga practices\n* Agreeing to comply with the study protocol, including attendance at intervention sessions and completion of all assessments\n\nExclusion Criteria:\n\n* Inability to provide reliable responses due to the presence of active psychotic disorder, bipolar disorder, or severe cognitive impairment\n* Being in an acute psychological crisis\n* Initiation of intensive psychotherapy targeting trauma symptoms (e.g., trauma-focused therapy) within the past 3 months or participation in a similar structured psychosocial intervention during the study period\n* Presence of serious musculoskeletal, cardiovascular, or neurological conditions or injuries that would prevent participation in yoga, or medical restriction of physical activity by a physician\n* Having an established regular practice of yoga or meditation","FEMALE","25 Years",{"count":60,"type":21},46,[24],"The aim of this study is to evaluate the effects of a trauma-informed yoga intervention on psychological trauma symptoms, difficulties in emotion regulation, and interoceptive awareness in young adult women.",[64,65,66,28],"Trauma","Young Adult Females","Awareness",[68,69,70,71,72],"trauma-informed yoga","emotion regulation","interoceptive awareness","psychological trauma","randomized controlled trial","NOT_YET_RECRUITING","2026-05-09",{"date":76,"type":41},"2026-05-15",{"date":38,"type":21},{"date":79,"type":21},"2026-11-30",{"name":81,"class":48},"Saglik Bilimleri Universitesi",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":90,"briefSummary":91,"conditions":92,"keywords":99,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":49},"100489298","a-precision-medicine-approach-to-target-engagement-for-emotion-regulation-100489298","NCT05651295","A Precision Medicine Approach to Target Engagement for Emotion Regulation","Inclusion Criteria:\n\n* Elevated emotion dysregulation\n\nExclusion Criteria:\n\n* Lack of proficiency in English\n* No access to smartphone\n* Conditions requiring greater than outpatient care",{"count":89,"type":21},390,[24],"The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity. Second, using data from an initial sample, the investigators will prospectively assign an independent sample of participants to receive their predicted optimal or non-optimal skills to determine if it is feasible and efficacious to match participants to the most appropriate training condition. Results of these studies may identify the mechanisms by which emotion regulation interventions impact emotional functioning and allow for the development of personalized, evidence-based, and scalable emotion regulation interventions.",[28,93,94,95,96,97,98],"Depression","Anxiety","Borderline Personality Disorder","Obsessive-Compulsive Disorder","Posttraumatic Stress Disorder","Eating Disorders",[100,101,102,103],"cognitive-behavior therapy","mechanism","ecological momentary assessment","personalization","2026-05-07",{"date":106,"type":41},"2026-05-11",{"date":108,"type":41},"2023-09-29",{"date":110,"type":21},"2026-12-31",{"name":112,"class":48},"Matthew Southward, PhD",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":16,"sex":17,"minAge":120,"maxAge":18,"enrollmentInfo":121,"targetDuration":4,"studyType":22,"phases":123,"briefSummary":124,"conditions":125,"keywords":128,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":4},"100606288","transforming-adolescent-perception-and-mental-health-through-meditation-and-cognitive-reappraisal-a-mixed-method-study-100606288","NCT07173608","Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study","THRIVE","Inclusion Criteria:\n\n* Individuals between15-18 years of age\n* Ability to understand study instructions and provide informed consent\u002Fassent. (parental consent for minors)\n* Access to internet and a device to complete online study activities\n* Currently residing in the United States\n* Willing and able to travel to the hospital location in Boston for study procedures.\n\nExclusion Criteria:\n\n* Non-English speaking (Justification: the intervention and assessment instruments are not validated in a sufficient range of languages, and the research team lacks polylingual capabilities or the financial resources to hire interpreters for the duration of all proposed assessments.)\n* Practicing meditation regularly in the past 6 months (4 or more times per week for 4 weeks or more in the past 6 months)\n* History of psychiatric illness such as severe anxiety, severe depression, posttraumatic stress disorder (PTSD), Schizophrenia or bipolar disorder\n* Current use of cognition enhancing drugs\n* Current management for chronic pain\n* History (within past 5 years) of seizure, brain surgery or any condition causing cognitive decline.\n* Active history (within the last 5 years) of alcohol or drug abuse.\n* Current pregnancy or planning to become pregnant in the next 6 months\n* Currently enrolled in another interventional study that could impact the primary outcome, as determined by the PI\n* Significant visual impairment\n* Subject has previously learned the intervention.\n* Subject has contraindications for MRI (Detailed in the eligibility screening questions)","15 Years",{"count":122,"type":21},96,[24],"This study will evaluate how a comprehensive meditation-based program, Inner Engineering, supports teens ages 15-18 in becoming more joyful, focused, resilient, and better equipped to manage stress and thrive. Through this study, researchers will examine whether practices like meditation, yoga, and cognitive reframing can help adolescents view and respond to challenges with greater clarity and balance. The study will assess mental and physical impacts through self-report, physiological, and neuroimaging methods.",[126,127,28],"Meditation","Cognitive Reappraisal",[129,130,131,132,133,134,135,136,137,138],"meditation","Inner Engineering","Shambhavi Mahamudra Kriya","EEG","Functional MRI","MRI","Cognition","Mindfulness","Mental Health","Adolescent","2026-04-22",{"date":141,"type":41},"2026-04-23",{"date":143,"type":21},"2026-05",{"date":145,"type":21},"2028-03",{"name":147,"class":48},"Beth Israel Deaconess Medical Center",{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":152,"acronym":153,"eligibilityCriteria":154,"healthyVolunteers":16,"sex":17,"minAge":155,"maxAge":18,"enrollmentInfo":156,"targetDuration":4,"studyType":22,"phases":157,"briefSummary":158,"conditions":159,"keywords":163,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":4},"100630066","feasibility-study-of-a-compassionate-mindful-resilience-cmr-intervention-to-improve-mental-health-well-being-outcomes-among-youth-in-thailand-100630066","NCT07482839","Feasibility Study of a Compassionate Mindful Resilience (CMR) Intervention to Improve Mental Health Well-being Outcomes Among Youth in Thailand","CMR-YOUTH-THAI","Inclusion Criteria:\n\n* Adolescents between 16 and 18 years of age at the time of enrollment.\n* Current students in Grades 10 to 12 (Mathayom 4-6) at a Thai Secondary School in Northeastern Thailand.\n* Willingness to engage in a mindfulness-based intervention programme.\n* Ability to understand and communicate in the Thai language.\n* Ability to provide informed consent (dual consent from both the student and a parent\u002Flegal guardian is required).\n\nExclusion Criteria:\n\n* Significant mental health conditions that may impede participation, such as schizophrenia, bipolar I disorder, or severe major depression with psychotic features.\n* Cognitive impairments that prevent comprehension of the mindfulness intervention.\n* Concurrent involvement in another psychological intervention that might confound the study results.","16 Years",{"count":60,"type":21},[24],"This study is a single-arm feasibility trial designed to evaluate the implementation, acceptability, and preliminary effects of a culturally adapted Compassionate Mindful Resilience (CMR) intervention among adolescents in Thailand. The study is conducted in a secondary school setting and targets students aged 16 to 18 years.\n\nAdolescence is a critical developmental period associated with increased emotional vulnerability, academic pressure, and exposure to mental health risks. In Thailand, recent evidence indicates rising levels of stress, anxiety, and reduced psychological well-being among young people. School-based preventive interventions that strengthen internal coping skills are therefore a public health priority. While mindfulness-based interventions have demonstrated benefits in Western contexts, there is limited evidence regarding compassion-focused mindfulness programs that are culturally adapted for Thai adolescents.\n\nThe CMR intervention is a structured, manualized behavioral program that integrates mindfulness, self-compassion, and resilience-building skills. The program was originally developed by MindfulnessUK and subsequently adapted for the Thai adolescent context through a co-production process involving students, teachers, and school counselors. Cultural adaptations focused on language use, contextual relevance of examples, and alignment with the Thai educational environment, while maintaining fidelity to the core theoretical framework.\n\nAll participants enrolled in the study will receive the CMR intervention. The program consists of four weekly group sessions, each lasting approximately 90 minutes, delivered after school hours to minimize disruption to academic activities. Sessions include guided mindfulness practices, group discussions, and practical exercises aimed at increasing present-moment awareness, cultivating self-compassion, improving emotional regulation, and strengthening resilience. Home practice activities are encouraged between sessions to support skill integration into daily life.\n\nThe primary objective of the study is to assess feasibility. Feasibility outcomes include recruitment rate, retention rate, session attendance, intervention fidelity, and participant acceptability. These indicators will inform whether the intervention can be delivered as planned in a Thai school setting and whether progression to a larger-scale trial is justified.\n\nSecondary objectives explore preliminary changes in mental health-related outcomes. These include mindfulness, self-compassion, resilience, and overall well-being, measured using validated Thai-language instruments before and after completion of the intervention. Although the study is not powered to test effectiveness, these data will provide estimates of variability and potential effect sizes to inform the design of a future randomized controlled trial.\n\nParticipant safety is addressed through a predefined distress protocol. A school counselor is available during all intervention sessions to provide immediate support if participants experience emotional distress. Ethical approval has been obtained from the relevant institutional ethics committee, and written assent from participants, along with parental or guardian consent, is required prior to enrollment.\n\nOverall, this feasibility study will generate critical information on the practicality, acceptability, and preliminary impact of the Compassionate Mindful Resilience program for adolescents in Thailand. The findings will guide the development of a future definitive trial and contribute to the evidence base for culturally appropriate, school-based mental health promotion interventions in low- and middle-income settings.",[160,28,161,162],"Mental Health Well-being","Psychological Resilience","Substance Use Prevention",[164,165,166,167,168,169,170,171,172],"Compassionate Mindful Resilience (CMR)","Mindfulness-Based Intervention (MBI)","Adolescents","Thailand","Secondary School","Feasibility Study","Co-production","Self-compassion","Youth Mental Health","2026-04-18",{"date":175,"type":41},"2026-04-21",{"date":177,"type":21},"2026-05-01",{"date":179,"type":21},"2027-12-30",{"name":181,"class":48},"Queen's University, Belfast",{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":186,"acronym":4,"eligibilityCriteria":187,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":188,"enrollmentInfo":189,"targetDuration":4,"studyType":22,"phases":191,"briefSummary":192,"conditions":193,"keywords":207,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":220},"100471118","art-therapy-and-emotional-well-being-in-military-populations-with-posttraumatic-stress-symptoms-100471118","NCT05414708","Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms","Inclusion Criteria:\n\n* DEERS Eligible\n* Active Duty or Veteran separated within the past 10 years\n* Significant posttraumatic stress symptoms (score of \\>\u002F=31 on the PCL-5)\n\nExclusion Criteria:\n\n* History of moderate, severe, or penetrating brain injury\n* History of psychotic disorder, bipolar disorder, or active suicidal or homicidal ideation\n* History of multiple sclerosis, Huntington's disease, or Alzheimer's disease\n* History of stroke or myocardial infarction\n* History of brain tumor\n* History of seizures\n* Contradictions for MRI (for example, participants will be excluded for pregnancy, metal implants or suspected shrapnel, aneurysm\u002Fintracranial clips, cardiac pacemakers or implanted programmable devices or pumps)\n* Unable to provide informed consent\n* History of previous exposure to art therapy\n* Active substance use disorder","64 Years",{"count":190,"type":21},40,[24],"Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members. This research hopes to learn about the effects of art therapy on emotional expression and regulation in service members as well as the neurological systems at work. If a participant chooses to be in this study, he or she will attend eleven sessions over a period of six to eight months. The first session will be an interview and self-assessment questionnaires to collect information on a variety of symptoms, experiences, and personality traits, and an MRI scan. During the MRI scan, participants will be asked to perform a task where they will be shown a series of neutral and negative images. The following eight sessions will be one-hour art therapy sessions with a certified art therapist. The tenth session will consist of the same self-assessment questionnaires and another MRI scan. The final session will consist of some of the same questionnaires from the tenth visit, as well as a qualitative interview done virtually three months after the tenth visit.",[194,195,196,97,197,198,199,200,201,202,203,204,205,28,206],"PTSD","Military Activity","Post-Traumatic Headache","Posttraumatic Stress Disorder, Delayed Onset","Sleep Disturbance","Nightmare","Irritable Mood","Anger","Combat and Operational Stress Reaction","Combat Stress Disorders","Military Family","Military Operations","Emotion Processing",[194,208,209],"Military","Art Therapy","2026-01-06",{"date":212,"type":41},"2026-01-08",{"date":214,"type":41},"2022-02-01",{"date":216,"type":21},"2027-12",{"name":218,"class":219},"Walter Reed National Military Medical Center","FED",2,{"id":222,"slug":223,"hasResults":11,"nctId":224,"briefTitle":225,"officialTitle":226,"acronym":4,"eligibilityCriteria":227,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":228,"enrollmentInfo":229,"targetDuration":4,"studyType":22,"phases":231,"briefSummary":232,"conditions":233,"keywords":236,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":245,"startDateStruct":247,"completionDateStruct":249,"leadSponsor":251,"locationsCount":49},"100617218","group-skills-training-for-body-awareness-and-managing-emotions-100617218","NCT07315763","Group Skills Training for Body Awareness and Managing Emotions","Polyvagal Informed Group Skills Training for Body Awareness and Managing Emotions for People Living With Obesity","Inclusion Criteria:\n\n* Able to commit to the duration of the study from baseline to end of follow up period (up to 16 weeks)\n* Current service user of Specialist Weight Management Programme\n* Aged 18-65.\n* Good level of English spoken, reading and writing.\n* Identified by the University of Rhode Island Change Assessment (URICA) to be in the Contemplation, Action or Maintenance stage of change.\n* Access to device with internet connection to complete online questionnaires and with camera for online group sessions.\n\nExclusion Criteria:\n\n* Identified by the University of Rhode Island Change Assessment (URICA) to be in Pre-contemplation stage of change\n* Currently in psychological skills training treatment during the 16-week study period\n* History of organic brain injury or cognitive impairment\n* Clients presenting with suicidal intent","65 Years",{"count":230,"type":21},10,[24],"The goal of this study is to evaluate the effectiveness of a skills training group informed by polyvagal theory, when delivered in an NHS setting, for those living with obesity. Polyvagal Theory in Therapy encourages individuals to be curious, respect how their nervous system works, and notice and respond to bodily sensations. Research shows that interoception, which is the ability to sense and understand what is happening inside the body such as recognising hunger, pain, or emotions, may be challenging for people in larger bodies. These challenges have been connected to difficulties in managing emotions which may lead to behaviours such as emotional eating. This points to the need for a therapeutic approach that helps people both notice what's happening in their bodies and trust those signals enough to be able to respond in healthy ways. This project will test whether a novel polyvagal informed skills training group can improve body awareness (interoception) and emotional regulation for people within an NHS specialist weight management service using a single case experimental design. Participants will be randomly assigned a baseline period of either 14 or 21 (phase A of the design) using computer-generated randomisation. During this phase, participants will complete outcome measures. The skills training intervention phase (phase B) will begin immediately following the individual's baseline period. The intervention is the six session group polyvagal theory-informed skills training. A four-week follow-up period will follow the skills training group, during which participants will continue to complete the same outcome measures they had used in the first two phases. This phase will help assess whether immediate treatment gains are maintained and\u002For whether delayed treatment gains occur. Trend analysis within this phase will show whether improvement or decline occurs post-skills training.",[234,235,28],"Body Awareness","Obesity",[237,238,239,240,241,242,243,235],"Body awareness","Specialist Weight Management Service","Polyvagal Theory","Emotional regulation","Polyvagal theory in therapy","Single case experimental design","Skills training","2026-01-05",{"date":246,"type":41},"2026-01-07",{"date":248,"type":21},"2026-01-27",{"date":250,"type":21},"2026-09-30",{"name":252,"class":48},"Royal Holloway University",{"id":254,"slug":255,"hasResults":11,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":4,"eligibilityCriteria":259,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":260,"enrollmentInfo":261,"targetDuration":4,"studyType":22,"phases":263,"briefSummary":264,"conditions":265,"keywords":4,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":4},"100609695","neurofeedback-and-well-being-among-people-with-co-occurring-obsessive-compulsive-disorder-and-post-traumatic-stress-symptoms-100609695","NCT07217925","Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms","Exploring the Influence of Neurofeedback on the Well-Being of People With Symptoms of Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms","Inclusion Criteria:\n\n1. being a client placed on the clinic waitlist to receive exposure-response prevention for OCD symptoms at the Anxiety and OCD Treatment Center of Ann Arbor, in Ann Arbor, MI.\n2. having self-reported symptoms of OCD;\n3. having post-traumatic stress symptoms as indicated by a score of 3 or higher on the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5) screening measure;\n4. being age 18+.\n5. being a citizen of the United States of America -\n\nExclusion Criteria:\n\n1. a lifetime history of significant untreated mental illness (not currently treated schizophrenia, schizoaffective disorder, bipolar disorder, or substance use disorder) or neurological or pervasive developmental disorder;\n2. a documented history of epilepsy;\n3. lifetime history of any head injury with loss of consciousness;\n4. current exposure domestic or intimate partner violence or otherwise state that their current living conditions are unsafe;\n5. current experiences of psychosis or suicidality within the last six months;\n6. currently taking, or in the past month has taken benzodiazepines, narcotic drugs, or cannabis;\n7. currently pregnant\n8. engagement in self-harming behaviors in the last 3 months that required medical attention;\n9. lack of competence to understand or consent to the study procedures;\n10. lack of fluency in written and spoken English. -","90 Years",{"count":262,"type":21},20,[24],"The proposed study will collect novel data evaluating the feasibility of a neurofeedback training program delivered to prospective clients with a history of clinically concerning trauma-related mental health symptoms who are on a wait list to receive obsessive compulsive disorder-specific psychotherapy at an outpatient mental health clinic. This study will evaluate the influence of neurofeedback training on participant's overall sense of well-being, and additionally, whether any enhanced well-being is subsequently associated with positive changes in symptoms of obsessive compulsive disorder, post-traumatic stress, dissociation and other trauma-related mental health symptoms, emotional regulation, etc.",[266,267,28,268,269],"Well-Being, Psychological","Mood Disturbance","Dissociation","Post Traumatic Stress Symptoms","2025-11-10",{"date":272,"type":41},"2025-11-12",{"date":274,"type":21},"2025-11",{"date":276,"type":21},"2029-01",{"name":278,"class":48},"Wayne State University",{"id":280,"slug":281,"hasResults":11,"nctId":282,"briefTitle":283,"officialTitle":283,"acronym":284,"eligibilityCriteria":285,"healthyVolunteers":16,"sex":17,"minAge":286,"maxAge":155,"enrollmentInfo":287,"targetDuration":4,"studyType":22,"phases":289,"briefSummary":290,"conditions":291,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":294,"lastUpdatePostDateStruct":295,"startDateStruct":297,"completionDateStruct":299,"leadSponsor":301,"locationsCount":49},"100534291","e-emotio-project-a-gamified-preventive-school-based-paradigm-using-virtual-reality-technologies-for-improving-emotional-regulation-in-children-and-adolescents-100534291","NCT06236919","E-Emotio Project A Gamified Preventive School-based Paradigm Using Virtual Reality Technologies for Improving Emotional Regulation in Children and Adolescents.","e-Emotio","Inclusion Criteria:\n\n* School-aged participants (aged 10 to 16 years old)\n* Individuals who provide consent to participate.\n\nExclusion Criteria:\n\n* A previous diagnosis of severe psychiatric (e.g., maniac, or psychotic symptoms).\n* A previous diagnosis of severe psychiatric neurodevelopmental disorders (i.e., severe autism spectrum disorders, intellectual disabilities, etc),\n* A previous diagnosis of severe physical, motor, or sensory impairments that could interfere with the examination or the VR program.\n* Participants who cannot understand Spanish.","10 Years",{"count":288,"type":21},160,[24],"Introduction and Significance: Preventive interventions have been shown to reduce the risk of developing anxiety and depression, making them a critical focus area in mental health promotion for children and adolescents. Enhancing emotion regulation (ER) skills in young people is one approach to preventing anxiety and depression, as ER involves cognitive processes of modifying thoughts and behaviors to manage emotional responses in different contexts. Executive functions (EF), such as cognitive flexibility, working memory, and inhibition, play a crucial role in ER development and regulation in children and adolescents. Recently, immersive virtual reality (IVR) has emerged as a novel tool for improving cognitive training interventions' accessibility and effectiveness. IVR allows users to experience immersive, three-dimensional environments, where they can interact with objects and events in a highly engaging and realistic way. Considering these developments, this study aims to explore the potential benefits of Enhance VR, a gamified IVR program designed to improve ER skills and reduce anxiety and depressive symptoms among children and adolescents.\n\nMethodology: The study will be a longitudinal, parallel, single-blind, randomized controlled pilot trial involving 80 Spanish - or English-speaking participants aged 10 to 16 years old. Participants will be excluded if they have severe psychiatric or neurodevelopmental disorders, physical, motor, or sensory impairments, or a risk of experiencing high cybersickness symptomatology during the VR experience. Participants will be randomly allocated into two groups: an experimental group receiving E-Emotio VR and a control group receiving a placebo-based VR relaxation experience. Both VR interventions will last five weeks, two times a week, for 30 minutes. The experimental group will engage in six games targeting cognitive flexibility, planning, reappraisal strategies, working memory, divided and sustained attention, and processing speed. The control group will be immersed in ten different nature-based VR environments and perform relaxation exercises. Baseline and post-intervention assessments will be conducted using age-adapted validated measures of depressive and anxiety symptoms, ER, executive function (working memory, cognitive flexibility, inhibition, and planning), and attention. Following the intervention, the assessment battery will be re-administered by a blinded assessor, and statistical analyses will be conducted for all the primary and secondary measures assessed before and after the intervention in both groups.\n\nConclusion: In summary, this study aims to contribute to the development of effective preventive interventions for emotion regulation and mental health symptoms in children and adolescents by promoting ER through gamified VR cognitive training. The study's findings could have significant implications for mental health research, educational and clinical practice. By exploring the potential benefits of VR cognitive training, this research has the potential to inform future studies and clinical interventions aimed at improving young people's mental health and well-being. The gamification of cognitive training interventions could be a powerful tool for increasing engagement and motivation among young people, making them more likely to participate in such interventions.",[28,292,94,93,293],"Virtual Reality","Executive Function","2025-09-30",{"date":296,"type":41},"2025-10-06",{"date":298,"type":41},"2024-02-01",{"date":300,"type":21},"2026-04-25",{"name":302,"class":48},"Universitat Internacional de Catalunya",{"id":304,"slug":305,"hasResults":11,"nctId":306,"briefTitle":307,"officialTitle":308,"acronym":4,"eligibilityCriteria":309,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":310,"targetDuration":4,"studyType":22,"phases":312,"briefSummary":313,"conditions":314,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":319,"lastUpdatePostDateStruct":320,"startDateStruct":322,"completionDateStruct":324,"leadSponsor":326,"locationsCount":220},"100569860","impact-of-mindful-self-compassion-therapy-on-self-harm-behaviors-emotional-regulation-and-quality-of-life-among-patients-with-borderline-personality-disorder-100569860","NCT06699732","Impact of Mindful Self-Compassion Therapy on Self Harm Behaviors, Emotional Regulation and Quality of Life Among Patients With Borderline Personality Disorder","Impact of Mindful Self-Compassion Therapy on Self Harm Behaviors, Emotional Regulation and Quality of Life Among Patients With Borderline Personality Disorder: A Randomized Controlled Trial","Inclusion Criteria:\n\n* 1\\. First time diagnosed non-hospitalized patients of Borderline Personality Disorder.\n\n  2\\. Patients of Borderline Personality Disorder experiencing psychological distress,low level of quality of life, social support, emotional dysregulation would be included.\n\n  3\\. Borderline Personality Disorder patients with age 18 years and above (both gender) from outpatient department (OPD) 4. Borderline personality patients who would be able to understand Urdu language and can give the informed consent\n* Exclusion criteria\n\nThe study would have the following exclusion criteria:\n\n1. Hospitalized patients of Borderline Personality\n2. Patients with Borderline Personality having other chronic co-morbid diseases such as cancer, cognitive deficits, and other chronic psychological disorders.\n3. Patients with Borderline Personality younger than 18 years of age",{"count":311,"type":21},60,[24],"The primary purpose of the study is to investigate whether Mindful Self-Compassion (MSC) therapy can significantly reduce self-harm behaviors, improve emotional regulation, and enhance the quality of life in individuals diagnosed with Borderline Personality Disorder (BPD). The study aims to contribute to the existing literature by providing robust evidence on the efficacy of MSC therapy for BPD, which could inform clinical practices and improve treatment outcomes",[315,28,316,317,318],"Psychological Distress","Self Harm","Quality of Life (QOL)","Borderline Personality Disorder (BPD)","2025-08-29",{"date":321,"type":41},"2025-09-02",{"date":323,"type":41},"2024-09-21",{"date":325,"type":21},"2025-12-30",{"name":327,"class":48},"Fatima Jinnah Women University",{"id":329,"slug":330,"hasResults":11,"nctId":331,"briefTitle":332,"officialTitle":333,"acronym":4,"eligibilityCriteria":334,"healthyVolunteers":16,"sex":17,"minAge":335,"maxAge":336,"enrollmentInfo":337,"targetDuration":4,"studyType":22,"phases":339,"briefSummary":340,"conditions":341,"keywords":344,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":350,"lastUpdatePostDateStruct":351,"startDateStruct":353,"completionDateStruct":354,"leadSponsor":356,"locationsCount":4},"100574314","effectiveness-of-robot-assisted-intervention-and-sensory-integration-therapy-in-enhancing-social-emotional-skills-in-children-with-autism-100574314","NCT06757673","Effectiveness of Robot-Assisted Intervention and Sensory Integration Therapy in Enhancing Social-Emotional Skills in Children With Autism","Effectiveness of Robot-assisted Interaction Compared to Sensory Integration for Social Emotion Control in Autism Spectrum Disorder","Inclusion Criteria:\n\n1. Children aged 4-6 years, regardless of gender.\n2. Diagnosed with autism spectrum disorder (ASD) or suspected ASD.\n3. Cognitive ability: Developmental Quotient (DQ) ≥ 70, as assessed by the Comprehensive 4. Developmental Inventory for Infants and Toddlers (CDIIT).Social-emotional ability: DQ \\\u003C 85, as assessed by CDIIT, indicating challenges in emotional regulation and social skills.\n\n5\\. No significant physical or psychological conditions that could interfere with participation in the intervention.\n\nExclusion Criteria:\n\n1. Children younger than 4 years or older than 6 years.\n2. Cognitive ability: DQ \\\u003C 70, as assessed by CDIIT, indicating limited learning potential.\n3. Social-emotional ability: DQ ≥ 85, as assessed by CDIIT, indicating normal emotional and social functioning.\n4. Any physical or psychological condition deemed by the investigators to interfere with the intervention or assessments.","4 Years","6 Years",{"count":338,"type":21},12,[24],"This study is designed to evaluate and compare the impact of robot-assisted intervention using a smart robot (Kebbi Air) and traditional sensory integration therapy on improving social-emotional skills in children diagnosed with autism spectrum disorder (ASD) or suspected ASD. The study will enroll children aged 4 to 6 years, who will be randomly assigned to one of two groups: the experimental group, which will participate in guided interactions with the smart robot, or the control group, which will receive sensory integration therapy tailored to enhance emotional and social functioning.\n\nThe research aims to explore whether interactions with the robot, which are designed to simulate real-world social scenarios, can provide comparable or enhanced benefits compared to traditional sensory integration methods. Pre- and post-intervention assessments will be conducted over a 12-week period, using tools like the Achenbach System of Empirically Based Assessment (ASEBA) and the Sensory Processing Measure (SPM) to measure changes in emotional regulation, sensory processing abilities, and social engagement. The study hypothesizes that the robot-assisted intervention will offer a novel, engaging, and effective approach to supporting the developmental needs of children with ASD.",[342,28,343],"Autism Spectrum Disorder","Sensory Integration Dysfunction",[342,345,346,347,348,349],"Sensory Integration","Robot-Assisted Therapy","Social-Emotional Skills","Early Intervention","Occupational Therapy","2025-01-07",{"date":352,"type":41},"2025-01-09",{"date":350,"type":21},{"date":355,"type":21},"2025-08-31",{"name":357,"class":48},"National Taiwan University Hospital",{"id":359,"slug":360,"hasResults":11,"nctId":361,"briefTitle":362,"officialTitle":363,"acronym":364,"eligibilityCriteria":365,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":366,"targetDuration":4,"studyType":22,"phases":368,"briefSummary":369,"conditions":370,"keywords":378,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":384,"lastUpdatePostDateStruct":385,"startDateStruct":387,"completionDateStruct":389,"leadSponsor":391,"locationsCount":49},"100558208","evaluation-of-the-parenting-in-the-moment-online-program-for-forcibly-displaced-families-100558208","NCT06548126","Evaluation of the Parenting in the Moment Online Program for Forcibly Displaced Families","Evaluation of the Parenting in the Moment Program for Forcibly Displaced Families","PIMonline","Inclusion Criteria:\n\n1. The person is a primary Caregiver to a Child age 6 - 12 years in their care and living with them at least half the time\n2. The Caregiver is at least 18 years of age\n3. The Caregiver is able to do a program delivered in English, Spanish, Arabic or French, and to answer questions in English, Spanish, Arabic or French.\n4. The Caregiver resides in the United States\n5. The Caregiver has reliable access to a smart phone, tablet, or computer with stable internet access.\n6. One Parent, not necessarily the PCG, has experienced forced displacement in the past 10 years\n7. The Parent is able to consent for self and Child If the PCG does not have the legal right to provide Parent permission for the Child to participate, the Child's legal Parent\u002FCaregiver can provide consent while the PCG actively participates in the study with the Child.\n8. The Child is able to answer questions in English, Spanish, Arabic or French.\n\nExclusion Criteria:\n\n1. Prisoners\n2. Impaired decision-making capacity\n3. Disclosed active psychosis of Parent or Child\n4. Open Child protection case for abuse or neglect in the family",{"count":367,"type":21},720,[24],"This Randomized Controlled Trial will test the effectiveness of the Parenting in the Moment (PIM) online parenting program for parents with experiences of forced displacement.\n\nThe primary objective of this study is to conduct a summative (impact) evaluation of the PIM online parenting program as an in-home parent, skill-based program for parents of school-aged children, using a randomized controlled trial research design with community partnerships that inform the research throughout. The longer-term objectives are to build the evidence-base for in-home parent skill-based programs with strong empirical support (i.e., eligible for listing on the Families First Clearinghouse) and increase access to parenting programs for forcibly displaced families thereby improving child safety and wellbeing and strengthening their public health support.\n\n720 families will be recruited with forced migration backgrounds and within 10 years of arrival in the USA; 360 families will be assigned to the PIMonline program and 360 to a family resource list only, wait-list control group. Families will be recruited using stratified random sampling within the four PIM language groups: English, Spanish, Arabic, French. Within each language, half the families will be assigned to the PIMonline intervention program and the other half will be assigned to receiving a Family Resource List with access to the PIMonline program once the study ends.\n\nOne parent and one child per eligible family may participate. Data collection with participating families will take place at baseline (T1), 4-months after baseline (T2) and finally, 16 months after baseline (T3). Data collection includes caregiver online surveys, caregiver and child Zoom recorded Family Interaction Task conversations and interviewer administered child surveys for children aged 8-12 at each time point. Standardized, reliable and valid measures in the four languages will be used to assess change in outcomes through the surveys. Longitudinal growth curve analysis will be used to test PIM intervention effects. Our extensive dissemination plan involves nationwide community partners in child welfare and services to forcibly displaced families.",[371,372,373,374,375,376,137,377,64,28],"Child Safety","Coercion","Child Wellbeing","Adjustment","Parenting","Post Traumatic Stress Disorder","Child Maltreatment",[379,380,381,382,383],"Forced displacement","Refugees","Parenting Program","Immigrant Parenting Program","Refugee Parenting Program","2024-09-16",{"date":386,"type":41},"2024-09-19",{"date":388,"type":41},"2024-09-12",{"date":390,"type":21},"2026-06-15",{"name":392,"class":48},"Arizona State University",{"id":394,"slug":395,"hasResults":11,"nctId":396,"briefTitle":397,"officialTitle":398,"acronym":4,"eligibilityCriteria":399,"healthyVolunteers":11,"sex":17,"minAge":335,"maxAge":155,"enrollmentInfo":400,"targetDuration":4,"studyType":22,"phases":402,"briefSummary":403,"conditions":404,"keywords":405,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":410,"lastUpdatePostDateStruct":411,"startDateStruct":412,"completionDateStruct":414,"leadSponsor":416,"locationsCount":4},"100560695","adding-printed-cbt-materials-to-a-pediatric-digital-intervention-100560695","NCT06580496","Adding Printed CBT Materials to a Pediatric Digital Intervention","Examining the Impact of Adding Printed CBT Materials to a Pediatric Digital Emotional Regulation Intervention","Inclusion Criteria:\n\n* Age 4-16 years old at time of enrollment\n* Regular access to WiFi (for Mightier gameplay device connection)\n* Independently elected to engage with Mightier program\n\nExclusion Criteria:\n\n* Previous use of Mightier\n* Under the age of 4\n* Older then 16 years of age",{"count":401,"type":21},150,[24],"The primary goal of this study is to demonstrate that engaging with \"offscreen\" physical materials that focus on teaching and practicing Cognitive Behavioral Therapy-based skills alongside a digital emotional regulation intervention results in greater symptom improvement in kids than engaging with the digital intervention alone.\n\nParticipants are children who are using Mightier a video-game based heart rate biofeedback intervention used to build emotion regulation. Caregivers will be asked to complete a short survey prior to their child's first play and then complete that survey at 12 weeks post baseline.\n\nThe pre-post self-report design, combined with analyses accounting for engagement with offscreen materials will allow the investigators to observe changes during Mightier use and relate those changes to type of program engagement. (edited)",[28],[406,407,408,409],"Emotional Dysregulation","Pediatric","CBT","Digital Intervention","2024-09-03",{"date":386,"type":41},{"date":413,"type":21},"2024-09-15",{"date":415,"type":21},"2026-02-15",{"name":417,"class":418},"Neuromotion Labs","INDUSTRY",{"id":420,"slug":421,"hasResults":11,"nctId":422,"briefTitle":423,"officialTitle":424,"acronym":425,"eligibilityCriteria":426,"healthyVolunteers":11,"sex":17,"minAge":286,"maxAge":155,"enrollmentInfo":427,"targetDuration":4,"studyType":22,"phases":429,"briefSummary":430,"conditions":431,"keywords":433,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":437,"lastUpdatePostDateStruct":438,"startDateStruct":440,"completionDateStruct":442,"leadSponsor":444,"locationsCount":49},"100507674","students-with-involved-families-and-teachers-100507674","NCT05890456","Students With Involved Families and Teachers","Efficacy of the Students With Involved Families and Teachers (SWIFT) Program for Students With Emotional and Behavioral Disorders","SWIFT-RCT","Inclusion Criteria:\n\n* Students in grades 5 through 8\n* In school districts in the the Lane Education Service District\n* Eligible for or at risk of eligibility for special education services for emotional or behavior disorders\n* Transitioning or at risk of transitioning between school settings or placements\n* English or Spanish speaking\n\nExclusion Criteria:\n\n* Students receiving intensive family and school support services from local community mental health agencies\n* Students with a hearing or vision impairment that would limit participation in the program components or the assessment protocol.",{"count":428,"type":21},320,[24],"PURPOSE: In the proposed project, the investigators seek to examine whether the SWIFT Program might be efficacious to improve students' prosocial skills and emotion and behavior regulation and improve home-school communication and the use of positive parenting practices for families. The investigators will also test whether the SWIFT program might be efficacious to improve students' longer-term school adjustment and parents' involvement in school.\n\nSETTING: Study activities will take place in ten school districts in Lane County, OR. The districts have approximately 10,000 middle school students (Grades 6-8), and approximately 60% of students are eligible for free and reduced price lunch. Some participating districts participated in the IES-funded Goal 2 study to develop the SWIFT Program.\n\nPOPULATION: 320 students in Grades 6-8 who are receiving special education services for emotional or behavioral disorders, and transitioning or at risk of transitioning between school settings and placements will be recruited. Parents and content area teachers of all participating students will be recruited to complete assessment measures. It is expected that up to 15% of the children in the study will be of Latino ethnicity and approximately 60% will be European-American and 10-20% will be of other or multiple ethnicities.\n\nINTERVENTION: The SWIFT Program is a 9-12 month intervention that includes four components: (a) behavioral progress monitoring, (b) case management of the intervention elements and coordination with the school, (c) parent support to promote parent engagement\u002Fcollaboration with the school and study routines in the home, and (d) behavioral skills coaching for students.\n\nSERVICES AS USUAL (SAU) CONTROL CONDITION: The SAU students and families will continue to receive any services that they were receiving prior to their entry into the study (as will the SWIFT students and families). These may include school-based interventions and supports and related services as required in the student's IEP.",[28,432,375],"Adolescent Behavior",[434,435,436],"Positive Parenting","Behavior Regulation","Academic Success","2023-05-26",{"date":439,"type":41},"2023-06-06",{"date":441,"type":41},"2021-12-22",{"date":443,"type":21},"2026-06-30",{"name":445,"class":48},"Oregon Social Learning Center"]