[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"end-of-life-decision-making\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:end-of-life-decision-making":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100621414","a-culturally-adapted-decision-aid-intervention-to-support-chinese-american-dementia-caregivers-in-feeding-related-decisions-100621414",false,"NCT07370311","A Culturally Adapted Decision Aid Intervention to Support Chinese American Dementia Caregivers in Feeding-Related Decisions","Inclusion Criteria:\n\n* Age 21 years and older\n* Self-identify as Chinese\n* Providing caregiving or involvement in end-of-life care decision-making for older Chinese adults with: a) moderate or advanced dementia, b) feeding difficulties, and c) poor oral intake, eating\u002Fswallowing problems, or weight loss\n\nExclusion Criteria:\n\n* Dementia patients are a) receiving tube feeding, b) enrolled in hospice care, or 3) have a documented preference against a feeding tube","ALL","21 Years","99 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","Family caregivers of people with dementia have to decide between tube feeding and hand feeding when persistent eating problems arise. This decision can be difficult for Chinese American dementia caregivers, due to the interplay of culture, potential absence of a patient's advance directive, poor understanding of dementia, and lack of knowledge on the risks and benefits of tube feeding. In this polit study, the principal investigator examines whether a culturally adapted decision aid intervention regarding feeding options named \"Chinese version of Making Choices Feeding Options for Patients with Dementia Decision Aid\" (CMCFODA) will improve Chinese American caregivers' decision-making about feeding options in patients with moderate or advanced dementia. The proposed study advances the field by providing critical evidence to inform the development and implementation of culturally adapted decision support interventions in end-of-life dementia care.",[26,27,28],"Dementia Caregivers","End of Life Decision Making","Advanced Dementia",[30,31,32,33],"Chinese Americans","feeding options","decision aid","decision coaching","RECRUITING","2026-06-15",{"date":37,"type":38},"2026-06-17","ACTUAL",{"date":40,"type":38},"2026-03-24",{"date":42,"type":20},"2028-07-31",{"name":44,"class":45},"Yaolin Pei","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":15,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":67,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":46},"100618117","coaching-doctors-and-nurses-to-improve-ethical-decision-making-in-team-100618117","NCT07327450","Coaching Doctors and Nurses to Improve Ethical Decision-making in Team","Coaching Doctors and Nurses to Improve Ethical Decision-making in Team: a Stepped Wedge Cluster Randomized Trial in 10 Departments of the Ghent University Hospital","CODE II","Inclusion Criteria:\n\n* Patients potentially receiving excessive treatment (PET) who are identified by clinicians during their first hospitalization. PET is defined as a patient in whom 2 or more clinicians doubt whether the treatment or treatment limitation code is consistent with their expected survival or quality of life (= \"too much\" or \"excessive treatment\") or whether the treatment limitation code is in line with the patient's or relatives' goals.\n* Family members of PET\n* Junior and senior doctors (including Department Heads) taking care of hospitalized patients\n* Nurses (including head nurses) taking care of hospitalized patients\n* Allied health professionals (psychologists, physical therapists, speech therapists, occupational therapists, social workers, spiritual care providers) taking care of hospitalized patients\n* PET admitted \u002F clinicians working in the 10 participating departments of of the Ghent University Hospital (Cardiology, Gastro-enterology and Hepatology, General Internal Medicine, Geriatrics, Hematology, Medical Oncology, Neurology, Nephrology (including dialysis unit), Pulmonology and the Medical ICU)\n\nExclusion Criteria:\n\n* PET with a previous written DNI-DNACPR order\n* Patients and family members of PET who are less than 18 years old and persons who cannot understand Ducth questionnaires","18 Years",{"count":57,"type":20},360,[23],"Literature and a pilot study performed in 2019 indicate room for enhancing openness to discuss ethical sensitive issues within and between teams, and improving goal-oriented care and decision-making for the benefit of the patient at end-of-life, worldwide and more specifically in Belgium and in the Ghent University Hospital. The CODE study intervention performed in 2021 suggests already an improvement in goal oriented care operationalized via written Do-Not-Intubate and Do-Not-Attempt Cardio-Pulmonary Resuscitation (DNI-DNACPR orders in the Ghent University Hospital. In this study, the investigators found a nearly doubling of the incidence in written DNI-DNACPR in patient potentially receiving excessive treatment (PET) (from 19.7% to 29.7%, p\\\u003C0.001) and in patients hospitalized for the first time (from 1.9% to 3.4%, p=0.011) without increasing one-year mortality, after coaching doctors during 4 months in self-reflective and empowering leadership, and coping with group dynamics. However, the investigators found no improvement in the perception of the quality of the ethical climate by clinicians, more specifically by nurses. Despite the fact that ethical decision-making is considered a strategic priority in the Ghent University Hospital and an intense communication campaign, clinicians identified also a much smaller number of PET during this interventional study than during the observational pilot study in 2019. Although fading attention for the study over time and visibility of the electronic CODE alert to identify PET was claimed as the main reasons by 75% and 50.7% of the nurses, respectively, 95% expressed the desire to keep on using this alert in the future. This underscores a deeper concern in nurses. More than 40% expressed fear of blaming doctors or skepticism regarding the impact of identifying PET. Nonetheless, 35% acknowledged improvement in interdisciplinary meetings about end-of-life issues since study initiation. These findings highlights the need to additionally coach the entire team in future studies. Indeed, creating a safe climate which enhances inter-professional shared decision-making for the benefit of the patient requires both, specific self-reflective and empowering leadership skills in doctors and head nurses (including the management of group dynamics in the interdisciplinary team), and confidence in speaking up in nurses and other health care professionals. This is what the investigators want to develop with this intervention. These skills will also help clinicians during patient and family meetings which will enable clinicians to better take into account the patient's and family's wishes.",[61,62,63,27,64,65,66],"Decision Making ,Shared","Leadership","End of Life Communication","End of Life Patients","Ethical Sensitivities","Coaching",[66,68,69,70,71,72,73],"Shared decision-making","Goal-oriented care","Ethical climate","Leaderschip","Communication","End-of-life","NOT_YET_RECRUITING","2026-04-03",{"date":77,"type":38},"2026-04-09",{"date":79,"type":20},"2026-04-01",{"date":81,"type":20},"2028-06-30",{"name":83,"class":45},"University Hospital, Ghent",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":15,"minAge":55,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":93,"phases":4,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":46},"100558493","end-of-life-decision-making-among-young-patients-with-advanced-cancer-a-grounded-theory-approach-100558493","NCT06551831","End-of-life Decision-making Among Young Patients With Advanced Cancer: a Grounded Theory Approach","Inclusion Criteria:\n\n* The patient has a solid tumor.\n* The age at initial cancer diagnosis is between 15 and 39 years.\n* The patient is at least 18 years old at the time of enrollment.\n* The patient has cancer with metastasis, either present at initial diagnosis or occurring after treatment or follow-up.\n* After metastasis, the first-line curative treatment is ineffective.\n\nExclusion Criteria:\n\n\\- Patients who, for any reason, including severe psychological distress (as determined by the attending physician, psychiatrist, or specialist nurse based on assessments and impressions during routine patient care), cognitive impairment, or physical limitations (such as frailty), are unable to communicate or participate in an interview lasting more than 30 minutes.","39 Years",{"count":92,"type":20},30,"OBSERVATIONAL","The purpose of this qualitative research is to use grounded theory to explore and describe the thoughts of young advanced cancer patients regarding end-of-life care and how these thoughts influence the related decision-making process.",[96],"End-of-life Decision-making",[98,99,100],"Young Patients","Advanced Cancer","Grounded Theory","2024-08-11",{"date":103,"type":38},"2024-08-13",{"date":105,"type":38},"2024-07-23",{"date":107,"type":20},"2025-07",{"name":109,"class":45},"National Taiwan University Hospital"]