[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"endometrial-biopsy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:endometrial-biopsy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100632423","phase-4-pipelle-vs-the-curved-aspirator-device-100632423",false,"NCT07513493","Pipelle vs the Curved Aspirator Device","The Conventional Pipelle vs the Curved Aspirator Device: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Patients \\\u003C18- 45 years with risk factors for endometrial cancer requiring endometrial biopsy.\n2. Patients ≥ 45 -95 years with abnormal uterine bleeding.\n3. Postmenopausal patients with bleeding or suspected endometrial pathology\n\nExclusion Criteria:\n\n1. Any patient who does not meet the inclusion criteria.\n2. Patients with contraindications to endometrial biopsy, including:\n\n   * Pregnancy\n   * Acute pelvic inflammatory disease\n   * Acute cervical infection\n   * Acute vaginal infection\n   * Cervical cancer\n   * Lack of patient consent",true,"FEMALE","18 Years","95 Years",{"count":21,"type":22},124,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","The primary aim of this study is to rigorously compare the efficacy of two commonly used endometrial sampling devices, the Pipelle and the Miltex, these devices are standard of care at Maimonides. This primary objective is critical, as the ability to accurately reach the uterine cavity is fundamental to obtaining adequate samples for histopathological evaluation, which is crucial for diagnosing endometrial cancer and other uterine pathologies.",[28],"Endometrial Biopsy",[30],"Gynecology","RECRUITING","2026-03-30",{"date":34,"type":35},"2026-04-07","ACTUAL",{"date":37,"type":35},"2026-01-02",{"date":39,"type":22},"2028-03-31",{"name":41,"class":42},"Maimonides Medical Center","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":43},"100596523","methoxyflurane-for-iud-insertion-and-endometrial-biopsy-100596523","NCT07046572","Methoxyflurane for IUD Insertion and Endometrial Biopsy","A Double-blind Placebo-controlled Randomized Controlled Trial (RCT) of 3ml Methoxyflurane for Intrauterine Device (IUD) Insertion and Endometrial Biopsy","Inclusion Criteria\n\n* Any participant ≥18 years and ≤ 65 years presenting for an IUD insertion or endometrial biopsy\n* For IUD insertion, only nulliparous patients\n* English speaking participants only\n* Availability of a ride home from the appointment\n\nExclusion Criteria\n\n* Use of pain medication that is not an NSAID or acetaminophen (e.g. opioids, benzodiazepines) within past 24 hours\n* Misoprostol administration within 24 hours\n* Breastfeeding\n* Any diagnosed chronic pain syndromes (e.g. fibromyalgia, vaginismus)\n* Allergy to methoxyflurane\n* Renal or liver disease\n* Known or genetically susceptible to malignant hyperthermia or a history of severe adverse reactions in either patient or relatives\n* Baseline vital signs of systolic blood pressure \\\u003C100, diastolic blood pressure \\\u003C60 and\u002For pulse \\\u003C60.\n* Previous unsuccessful office attempt of IUD insertion or endometrial biopsy by the same practitioner (note of clarification: previous unsuccessful IUD insertion or biopsy attempt by a different practitioner will still be eligible)\n* Clinically evident respiratory impairment","65 Years",{"count":53,"type":22},174,[55],"NA","The aim of this study is to determine if 3ml of inhaled Methoxyflurane, in the form of a Penthrox inhaler, reduces pain during IUD insertion and\u002For endometrial biopsy. The proposed study is a double-blind, placebo-controlled RCT.\n\nEach participant will be randomly assigned to one of two arms:\n\n1. Intervention (3ml of Methoxyflurane via a Penthrox inhaler)\n2. Placebo (3ml of normal saline via an identical placebo Penthrox inhaler)\n\nThe primary outcome is global pain score, which will be patient-reported by the 100 mm Visual Analogue Scale (VAS) 5-minutes following the procedure (endometrial biopsy or IUD insertion).",[28,58],"Intrauterine Devices",[60],"methoxyflurane","2025-07-28",{"date":63,"type":35},"2025-07-30",{"date":65,"type":35},"2025-07-24",{"date":67,"type":22},"2026-03-01",{"name":69,"class":42},"Mount Sinai Hospital, Canada",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":23,"phases":80,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":43},"100589952","the-effect-of-virtual-reality-on-women-undergoing-endometrial-biopsy-100589952","NCT06961097","The Effect of Virtual Reality on Women Undergoing Endometrial Biopsy","The Effect of Virtual Reality Glasess Application on Pain and Anxiety in Women Undergoing Endometrial Biopsy:A Randomized Controlled Research","Inclusion Criteria:\n\n* \\*Being over 18 years old\n\n  * Speaking and understanding Turkish\n  * Being willing to participate in the research\n\nExclusion Criteria:\n\n* Not volunteering to participate in research \\* Not speaking or understanding Turkish","70 Years",{"count":79,"type":22},64,[55],"The aim was to determine the effect of nature sounds and images that will be shown to women who underwent endometrial biopsy by using virtual reality glasses on pain and anxiety.\n\nHypotheses H0: Virtual reality glasses have no effect on women's pain and anxiety during endometrial biopsy.\n\nH1: Virtual reality glasses have an effect on women's pain and anxiety during endometrial biopsy.\n\nThe study will be carried out in two different groups. The practice will start with meeting the women who apply to the Radiology clinic for an endometrial biopsy. After the women are evaluated in terms of eligibility criteria for the research, the women who are eligible will be informed about the research and written informed consent will be obtained from the women who accept. The random distribution of women to the study groups will be carried out using the Block Randomization method. The following applications will be made to the groups.\n\nVirtual Reality Group In addition to the routine procedure, virtual reality glasses will be applied to the women in the virtual reality group of the research. Virtual reality glasses is a device that works on compatible smart mobile phones. After being taken to the gynecological table for the HSG procedure, the women included in the experimental group will be made to watch a video lasting an average of 15 minutes with virtual reality glasses until the procedure is completed. While watching the video, the relaxing nature sounds music of the video will be played in the practice room with a bluetooth speaker.\n\nControl Group Patients in the control group of the study will not be subjected to any treatment other than the routine procedure.",[28],"2025-07-16",{"date":85,"type":35},"2025-07-20",{"date":87,"type":35},"2025-05-01",{"date":89,"type":22},"2026-06-01",{"name":91,"class":42},"Ondokuz Mayıs University"]