[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"endometrial-polyp\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:endometrial-polyp":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100563805","the-effect-of-levonorgestrel-intrauterine-system-in-preventing-endometrial-polyps-recurrence-100563805",false,"NCT06620939","The Effect of Levonorgestrel Intrauterine System in Preventing Endometrial Polyps Recurrence","The Effect of Levonorgestrel Intrauterine System in Preventing Endometrial Polyps Recurrence After Hysteroscopic Polypectomy: Protocol of a Multi-center Randomised Controlled Trial","Inclusion Criteria:\n\n1. （1）Women age 20 to 48 years old;\n2. （2）Previous history of endometrial polypectomy;\n3. （3）Postoperative pathology confirmed endometrial polyps；\n4. （4）Women without fertility desire within 2 years；\n5. （5）Signed informed consent.\n\nExclusion Criteria:\n\n1. （1）Contraindications for a hysteroscopic polypectomy or LNG-IUS or not willing to receive this type surgery；\n2. （2）Women who have a positive pregnancy test；\n3. （3）A I and II type submucosal uterine leiomyoma, congenital uterine malformation, atypical endometrial polyps, a (suspected) malignancy, atypical endometrial cells, reproductive tract infections；\n4. （4）Postoperative pathology confirmed non-endometrial polyps；\n5. （5）Postoperative pathology confirmed endometrial proliferative diseases which need hormone drug therapy after surgery；\n6. （6）Treatment with hormonal three months before surgery；\n7. （7）The uterine cavity is more than 10 cm deep；\n8. （8）Women with severe diseases；\n9. （9）Women who were enrolled in another clinical study that could potentially impact the objectives of this study prior to their initial visit were excluded.\n10. （10）Unable to cooperate with the study procedures for various reasons, such as language comprehension difficulties, mental illness, inability to travel to the study center, or poor compliance.","FEMALE","20 Years","48 Years",{"count":20,"type":21},558,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to determine whether the LNG-IUS is more effective to that of expectant in preventing endometrial polyp recurrence after hysteroscopic polypectomy.\n\nResearchers will compare LNG-IUS to expectant management to see if LNG-IUS works to reduce the recurrence rate of endometrial polyps.\n\nParticipants will:\n\nReceive Mirena placement or not after hysteroscopic polypectomy； Be scheduled for a follow-up with TVCD to screen for endometrial polyps recurrence every 6 months.",[27],"Endometrial Polyp",[29,30],"Endometrial polyp","Levonorgestrel intrauterine system","NOT_YET_RECRUITING","2024-10-02",{"date":34,"type":35},"2024-10-04","ACTUAL",{"date":37,"type":21},"2024-12-01",{"date":39,"type":21},"2028-12-31",{"name":41,"class":42},"Zhang Jian","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":55,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100556581","5fr-bipolar-electrode-vs-conical-optical-5fr-fibers-for-dual-wave-length-diode-laser-for-hysteroscopic-polypectomy-100556581","NCT06526962","5Fr Bipolar Electrode vs. Conical Optical 5Fr Fibers for Dual Wave-length Diode Laser for Hysteroscopic Polypectomy","Comparison Between Two Different Tools for Outpatient Hysteroscopic Polypectomy: 5Fr Bipolar Electrode vs. Conical Optical 5Fr Fibers for Dual Wave-length Diode Laser","HYSTOP","Inclusion Criteria:\n\n* age ≥18 years and \\\u003C 60 years;\n* suspicion of a single endometrial polyp, documented by ultrasound, with dimensions less than 20 mm;\n* presence of abnormal uterine bleeding or history of infertility (defined as absence of conception after 12 months of regular unprotected intercourse aimed at conception);\n* consent to participate in the study.\n\nExclusion Criteria:\n\n* presence of multiple endometrial polyps;\n* presence of a single endometrial polyp with dimensions greater than 20 mm;\n* concurrent presence of intrauterine fibroids, focal or diffuse endometrial thickening, and\u002For intrauterine adhesions (synechiae);\n* current or recent use (\\\u003C 3 months) of anticoagulant drugs and\u002For Selective Estrogen Receptor Modulators (SERMs);\n* presence of another known cause of vaginal\u002Fcervical bleeding;\n* suspected adnexal pathology;\n* confirmed diagnosis of endometrial cancer;\n* suspected acute pelvic inflammation or recent history of pelvic inflammation (\\\u003C 6 months);\n* presence of tight cervical canal stenosis;\n* requirement for any type of anesthesia to perform the hysteroscopic procedure.","18 Years","60 Years",{"count":54,"type":21},214,"12 Months","OBSERVATIONAL","The primary objective of this study is to compare the performance of two different surgical instruments, the 5 Fr bipolar electrode and the 5 Fr angled conical optical fiber for dual wavelength diode laser, in performing hysteroscopic polypectomy in an outpatient setting.",[27],[60,61,27,62,63],"Hysteroscopy","Outpatient","Polypectomy","Dual Wave-Lenght Diode Laser","RECRUITING","2024-07-24",{"date":67,"type":35},"2024-07-30",{"date":69,"type":35},"2024-05-07",{"date":71,"type":21},"2025-05-07",{"name":73,"class":42},"University of Cagliari",1]