[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"endoscopic-video-assisted-nipple-sparing-mastectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:endoscopic-video-assisted-nipple-sparing-mastectomy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100637699","endoscopic-video-assisted-nipple-sparing-mastectomy-100637699",false,"NCT07579117","Endoscopic Video-Assisted Nipple-Sparing Mastectomy","EVA - Endoscopic Video-Assisted Nipple-Sparing Mastectomy (E-NSM): A Pilot Study","EVA","Inclusion Criteria:\n\n* Female patients aged ≥18 years\n* Candidates for nipple-sparing mastectomy (NSM) with immediate reconstruction\n* Histologically confirmed invasive carcinoma cT1N0, or carriers of pathogenic germline mutations undergoing prophylactic mastectomy\n* Breast size I-III and absence of significant glandular ptosis\n* Signed informed consent\n\nExclusion Criteria:\n\n* Inflammatory breast cancer\n* Locally advanced clinical stage (cT2-T4 or N+)\n* Ductal carcinoma in situ (DCIS) without invasive component\n* Previous radiotherapy to the affected breast\n* Locoregional recurrence\n* Clinical conditions contraindicating prosthetic reconstruction\n* Indication for skin-sparing (SSM) or skin-reducing mastectomy (SRM)\n* Ongoing or completed neoadjuvant chemotherapy before surgery\n* Refusal or inability to sign informed consent\n* Inability to complete scheduled follow-up","FEMALE","18 Years",{"count":20,"type":21},10,"ESTIMATED","INTERVENTIONAL",[24],"NA","Endoscopic video-assisted nipple-sparing mastectomy (E-NSM) is an advancement in minimally invasive breast surgery designed to reduce surgical trauma and improve cosmetic outcomes while maintaining strict oncologic safety. The procedure will be carried out by a dedicated surgical team in which at least one operator holds certified laparoscopic surgical training issued by a recognized scientific society, ensuring appropriate technical expertise and adherence to surgical safety standards.",[27,28,29],"Endoscopic Video-assisted Nipple-sparing Mastectomy","Breast Surgery","Breast Cancer","RECRUITING","2026-05-28",{"date":33,"type":34},"2026-06-01","ACTUAL",{"date":36,"type":34},"2026-05-23",{"date":38,"type":21},"2027-07",{"name":40,"class":41},"European Institute of Oncology","OTHER"]