[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"endovascular-treatments\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:endovascular-treatments":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,73,103],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100637050","a-prospective-randomized-study-comparing-the-safety-of-percutaneous-and-open-brachial-access-in-the-endovascular-treatment-of-peripheral-arterial-lesion-100637050",false,"NCT07573644","A Prospective Randomized Study Comparing the Safety of Percutaneous and Open Brachial Access in the Endovascular Treatment of Peripheral Arterial Lesion","BRAVO","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Endovascular diagnostic or therapeutic procedure via the brachial approach compatible with a 5F to 7F introducer\n* Patient affiliated with a social security scheme\n\nExclusion Criteria:\n\n* Adult patient under legal guardianship or curatorship\n* Contraindication to endovascular treatment\n* History of brachial artery puncture within the past 1 month\n* History of open surgical approach at the elbow\n* Presence of a stent at the puncture site\n* Acute upper limb ischemia\n* Life expectancy of less than one month\n* Patient refusal to participate in the study\n* Allergy to aspirin or clopidogrel\n* Pregnant woman\n* Patients not speaking the French language, refusing or unable to comply with the follow-up proposed in the study\n* Requirement for another endovascular procedure or open surgery within 30 days following the BRAVO study procedure","ALL","18 Years",{"count":19,"type":20},246,"ESTIMATED","INTERVENTIONAL",[23],"NA","Endovascular treatment tends to replace open surgery in the management of peripheral arterial disease. Access via the common femoral artery remains the primary approach for peripheral arterial interventions. Brachial artery access has emerged as a valid alternative when femoral access is not feasible. Brachial access can be achieved either percutaneously or through an open surgical approach at the elbow.\n\nA limited number of studies have reported complication rates associated with open and percutaneous brachial access in the treatment of peripheral arterial disease. These studies have shown higher complication rates for percutaneous access (ranging from 6% to 9%) compared with open brachial access (ranging from 1% to 2%). However, no direct comparison between the two approaches has been reported to date.\n\nThis study is the first to provide a direct, prospective, randomized comparison between open brachial access and percutaneous brachial access",[26,27,28],"Endovascular Treatments","Endovascular Surgery","Peripheral Arterial",[30,31,32],"peripheral arterial","endovascular treatments","endovascular surgery","NOT_YET_RECRUITING","2026-05-01",{"date":36,"type":37},"2026-05-07","ACTUAL",{"date":39,"type":20},"2026-06-01",{"date":41,"type":20},"2028-06-30",{"name":43,"class":44},"University Hospital, Brest","OTHER",11,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100610695","study-of-the-rate-of-progression-of-cerebral-ischemia-in-afro-caribbeans-100610695","NCT07230925","Study of the Rate of Progression of Cerebral Ischemia in Afro-Caribbeans","VESPERALS","* inclusion criteria:\n\n  * Patients aged 18 and over, admitted for IC due to LVO verified by medical imaging and hospitalized in neurology.\n  * Patients residing in Guadeloupe\n  * Afro-Caribbean patients: of African ancestry.\n  * Emergency inclusion, with exemption from obtaining consent due to the immediate life-threatening emergency situation of the patient (Article L1122-1-3 of the French Public Health Code); as soon as possible, consent to continue will be sought from the patient or, if applicable, from a relative or a trusted person.\n  * Patients affiliated to a social security scheme or equivalent\n* exclusion criteria:\n\n  * Patients under 18 years old\n  * Non-resident patients in Guadeloupe\n  * Protected persons (articles L1121-5, L1121-6 and L121-8 of the Public Health Code): pregnant or breastfeeding women, persons deprived of their liberty, under guardianship or curatorship)\n  * Withdrawal of consent during the study\n  * Patients not affiliated to a social security or equivalent scheme",{"count":54,"type":20},135,"OBSERVATIONAL","To compare the progression of cerebral ischemia from HF in Afro-Caribbean patients admitted to the CHUG to that of patients from Nantes included in the national ETIS registry.",[58,59,26],"Ischemic Stroke","Cerebral Ischemia",[61,62],"Cerebrovascular accident","Cerebral Blood Flow","2025-11-14",{"date":65,"type":37},"2025-11-17",{"date":67,"type":20},"2026-01",{"date":69,"type":20},"2028-01",{"name":71,"class":44},"Centre Hospitalier Universitaire de la Guadeloupe",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":84,"conditions":85,"keywords":89,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":72},"100599934","evt-in-acute-basilar-artery-occlusion-with-large-infarction-core-100599934","NCT07090941","EVT in Acute Basilar Artery Occlusion With Large Infarction Core","Trial of Endovascular Treatment in Acute Basilar Artery Occlusion Patients With a Large Infarct Core","BOLT","Inclusion Criteria:\n\n* 1\\. Age ≥18 years. 2. Symptoms and signs consistent with basilar artery ischemia. 3. Basilar artery or vertebral artery occlusion confirmed by computed tomography angiography (CTA), magnetic resonance angiography (MRA), digital subtraction angiography (DSA); if vertebral artery occlusion is present, it must completely obstruct blood flow to the basilar artery.\n\n  4\\. POST-NIHSS score ≥10 at randomization. 5. Time from symptom onset to randomization ≤24 hours (symptom onset defined as last known well time).\n\n  6\\. pc-ASPECTS of 3-5 on CT\u002FMRI (for patients aged \\\u003C80 years) or pc-ASPECTS of 3-7 (for patients aged ≥80 years).\n\n  7\\. Willingness of the patient or legally authorized representative to comply with protocol requirements and data collection procedures, with documented informed consent.\n\nExclusion Criteria:\n\n* 1\\. Pre-stroke modified Rankin Scale (mRS) score \\>2. 2. Factors in the target vessel that are expected to prevent completion of endovascular treatment.\n\n  3\\. Concurrent anterior and posterior circulation strokes or multivessel occlusions.\n\n  4\\. Significant mass effect with imaging or clinical signs of obstructive hydrocephalus or tonsillar herniation.\n\n  5\\. Basilar artery occlusion confirmed as chronic by prior imaging or investigator judgment.\n\n  6\\. Presence of untreated intracranial aneurysms, intracranial tumors (except small meningiomas), or intracranial vascular malformations.\n\n  7\\. Intracranial hemorrhage within the past 6 months, including parenchymal brain hemorrhage, intraventricular hemorrhage, or subarachnoid hemorrhage.\n\n  8\\. Presence of active bleeding, coagulation disorders, or uncorrectable bleeding tendencies.\n\n  9\\. Severe heart, liver, or kidney dysfunction or other severe systemic late-stage diseases.\n\n  10\\. Known allergy to iodine contrast agents or other treatment-related drugs. 11. Medically uncontrolled refractory hypertension (defined as persistent systolic blood pressure \\>185 mmHg or diastolic blood pressure \\>110 mmHg) (Note: Participants can be included if their blood pressure is controllable with medication and maintained at an acceptable level).\n\n  12\\. Uncontrollable blood glucose \\\u003C2.8 mmol\u002FL or \\>22.2 mmol\u002FL. 13. Pregnancy or breastfeeding. 14. Life expectancy \\\u003C6 months. 15. Participation in other clinical studies that may affect outcome assessment. 16. Investigator's judgment that the patient is unsuitable for participation in this study or may face significant risks (e.g., due to mental illness, cognitive, or emotional disorders preventing understanding and\u002For compliance with study procedures and\u002For follow-up).",{"count":82,"type":20},348,[23],"A multicenter, prospective, open-label, blinded endpoint, randomized controlled trial designed to evaluate the efficacy and safety of best medical management (BMM) combined with endovascular treatment (EVT) versus BMM alone in acute basilar artery occlusion (BAO) patients with large infarct cores.",[86,87,88,26],"Basilar Artery Occlusion","Large Ischemic Core","Large Core Infarct",[86,90,91],"Endovascular treatment","Large infarct core","RECRUITING","2025-07-21",{"date":95,"type":37},"2025-07-29",{"date":97,"type":20},"2025-08-01",{"date":99,"type":20},"2027-12-31",{"name":101,"class":102},"The First Affiliated Hospital of Hainan Medical University","OTHER_GOV",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":110,"targetDuration":112,"studyType":55,"phases":4,"briefSummary":113,"conditions":114,"keywords":118,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":72},"100551157","ischemic-post-conditioning-in-the-treatment-of-acute-ischemic-stroke-100551157","NCT06456437","Ischemic Post-conditioning in the Treatment of Acute Ischemic Stroke","Ischemic Post-conditioning in the Treatment of Acute Ischemic Stroke--a Multicenter, Prospective Cohort Study","Inclusion Criteria:\n\n* 1)Ischemic stroke confirmed by CT or MRI of the head;\n* 2\\) Large vessel occlusion confirmed by CTA or MRA of the head, including: intracranial internal carotid artery (ICA), middle cerebral artery (MCA M1\u002FM2), anterior cerebral artery (ACA A1\u002FA2), basilar artery (BA), vertebral artery (VA), and posterior cerebral artery (PCA P1\u002FP2);\n* 3\\) Recanalization of the occluded vessel at eTICI grade 2b\u002F3 as confirmed by DSA after thrombectomy;\n* 4)The patient\u002Flegally authorized representative has signed an informed consent form.\n\nExclusion Criteria:\n\n* 1\\) Inability to perform an MRI or CT scan for any reason;\n* 2）The patient has any condition that would interfere with neurologic assessment or psychiatric disorders;\n* 3）Stroke onset with seizures resulted in the inability to obtain an accurate NIHSS baseline;\n* 4）Pregnancy\n* 5）Other serious, advanced or terminal illness;",{"count":111,"type":20},200,"90 Days","Post-ischemic adaptation is a physical brain protective treatment strategy in which an ischemic event in an organ or tissue is treated and blood flow is restored, and an ischemic stimulus is given to local tissues to induce the production of anti-ischemic damage factors and reduce the damage associated with reperfusion therapy . Relevant basic studies have confirmed that post-ischemic adaptation can reduce infarct volume and promote neurological function recovery in animal models of cerebral infarction. Therefore, it may be beneficial to the recovery of neurological function in patients with acute ischemic stroke undergoing mechanical thrombus extraction.\n\nBased on the above background, the use of a balloon to repeatedly dilate-contract at the original occlusion site after revascularization to block and restore arterial flow may be an effective cerebroprotective treatment for patients with large-vessel occlusion who undergo thrombolysis. However, can this approach be safely used in patients with acute ischemic stroke treated with thrombolysis? What is the protocol for the length of time patients can tolerate post-ischemic adaptation? The application of this method in the treatment of acute ischemic stroke will be explored in this study.",[115,116,117,26],"Acute Ischemic Stroke","Large Vessel Occlusion","Intracranial Artery Occlusion With Cerebral Infarction",[119,120,121,122,123],"Endovascular treatments","Acute ischemic stroke","Retrieved clots","Ischemic Post-conditioning","Stroke etiology","2024-06-07",{"date":126,"type":37},"2024-06-13",{"date":128,"type":37},"2021-11-01",{"date":130,"type":20},"2025-12-31",{"name":132,"class":44},"Ming Wei"]