[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"endurance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:endurance":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100602772","effects-of-treadmill-based-gait-training-in-patients-with-stroke-100602772",false,"NCT07127861","Effects of Treadmill-Based Gait Training in Patients With Stroke","TreadmillACV","Inclusion Criteria:\n\n* Aged between 18 and 80 years\n* History of stroke at least six months prior\n* Presence of hemiplegia or hemiparesis\n* Ability to walk independently or with assistive devices\n\nExclusion Criteria:\n\n* Cognitive impairments interfering with the understanding of treatment procedures\n* Inability to get on and maintain position on the treadmill\n* Severe heart failure\n* Active inflammatory or infectious conditions at the time of evaluation\n* Attendance below 80% of scheduled sessions",true,"ALL","18 Years","80 Years",{"count":21,"type":22},24,"ESTIMATED","INTERVENTIONAL",[25],"NA","Hemiplegia is one of the most common sequelae after stroke. Most patients develop thermal asymmetry between the affected and contralateral sides of the body, as well as an asymmetric gait pattern characterized by differences in the duration of gait cycle phases, step length, cadence, and weight distribution between limbs. These patterns result in reduced aerobic capacity, endurance, energy efficiency, and walking speed, negatively impacting the patient's functional abilities.\n\nThere are different methodologies for the treatment gait impairments. Among them, treadmill training has been investigated as an effective therapeutic approach to post-stroke rehabilitation.\n\nTreadmill gait training may reduce asymmetry between hemibodies in hemiplegic patients.\n\nFor this reason, our aim is to describe the effects of treadmill training on gait, focusing on its impact on thermal asymmetry, walking speed, aerobic endurance, and the biomechanical and kinematic characteristics of gait.\n\nPatients with hemiplegia will undergo treadmill-based gait training to evaluate its influence on the recovery of this sequel of stroke.",[28,29,30,31,32,33],"Gait","Thermography","Walking Speed, Mesh id D000072797","Endurance","Step Time and Length","Gait Analysis","RECRUITING","2026-03-25",{"date":37,"type":38},"2026-03-31","ACTUAL",{"date":40,"type":38},"2025-09-14",{"date":42,"type":22},"2026-03",{"name":44,"class":45},"University of Salamanca","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":16,"sex":17,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":46},"100606996","effects-of-blood-flow-restriction-exercises-on-lumbar-muscle-endurance-and-balance-in-healthy-young-adults-100606996","NCT07182812","Effects of Blood Flow Restriction Exercises on Lumbar Muscle Endurance and Balance in Healthy Young Adults","Effects of Blood Flow Restriction Sit-to-Stand Exercises on Lumbar Extensor Muscle Endurance, Balance, and Physiological Parameters in Healthy Young Adults: A Randomized Controlled Trial","BFR-LUMBEX","Inclusion Criteria:\n\n* Age between 20 and 25 years\n* Healthy, without musculoskeletal disorders\n* No chronic neurological or systemic disease\n* No regular exercise program in the last 3 months\n* Voluntary participation with signed informed consent\n\nExclusion Criteria:\n\n* History of musculoskeletal disease, injury, or chronic low back pain\n* Neurological conditions or regular use of medications affecting balance or cardiovascular function\n* Pregnancy\n* Participation in regular lumbar or core exercise programs within the last 3 months\n* Any symptoms during exercise (e.g., excessive fatigue, dizziness, abnormal blood pressure changes) that may pose health risks\n* Withdrawal of consent or inability to comply with study protocol","20 Years","25 Years",{"count":58,"type":22},70,[25],"This study aims to examine the effects of blood flow restriction (BFR) exercises on back muscle endurance and balance in healthy young adults. BFR is a training method that involves applying controlled pressure to the limbs with a cuff while performing simple exercises. It has been shown to improve muscle strength and endurance even at low exercise loads, reducing stress on the joints.\n\nIn this study, participants aged 20 to 25 years will be randomly assigned to two groups. One group will perform sit-to-stand (STS) exercises combined with BFR, while the other group will perform the same exercises without BFR. The exercise program will last 6 weeks, with 2 sessions per week.\n\nBefore and after the program, participants will be assessed for:\n\nLumbar extensor muscle endurance (using the Biering-Sørensen test)\n\nBalance performance (using a computerized balance platform)\n\nPhysiological responses such as oxygen saturation, heart rate, and blood pressure\n\nThe purpose of this research is to determine whether BFR exercises improve spinal muscle endurance and balance more effectively than standard sit-to-stand exercises. The results may provide new insights into the use of BFR training as a safe and practical strategy for improving posture, preventing back problems, and enhancing physical performance in young adults.",[62,63,64,65,31],"Healthy Volunteers","Low Back Pain","Postural Balance","Muscle Fatigue",[67,68,69,70,64,71,72,73],"Blood Flow Restriction Exercise","Sit-to-Stand Exercise","Lumbar Extensor Muscles","Muscle Endurance","Physiological Parameters (Oxygen Saturation, Heart Rate, Blood Pressure)","Young Adults","Randomized Controlled Trial","NOT_YET_RECRUITING",{"date":76,"type":38},"2025-09-19",{"date":78,"type":22},"2025-09-29",{"date":80,"type":22},"2025-11-30",{"name":82,"class":45},"Mehmet Akif Guler",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":16,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":23,"phases":95,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":4},"100600071","efficacy-of-ln18178-in-improving-muscle-strength-aerobic-capacity-and-body-composition-in-healthy-young-males-100600071","NCT07092722","Efficacy of LN18178 in Improving Muscle Strength, Aerobic Capacity and Body Composition in Healthy Young Males","A Randomized, Double Blind, Placebo Controlled Parallel Arm Clinical Study to Evaluate the Efficacy of LN18178 in Improving Muscle Strength, Aerobic Capacity and Body Composition in Healthy Young Males","Inclusion Criteria:\n\n1. Untrained healthy male subjects aged between 36 and 50 years with a Body Mass Index (BMI) between 22 and 27 kg\u002Fm2.\n2. Willingness to do exercise training program during the course of the study.\n3. Subject considered generally healthy as per health history and routine clinical investigations.\n4. Ability to understand the risks and benefits of the protocol.\n5. Subject should provide written informed consent and agree to be available for regular follow up throughout the study duration.\n6. Subjects who are sexually active must agree to use adequate non-hormonal contraception during the study\n7. Subjects agree to maintain current diet and activity level.\n8. Subject agrees not to start any new therapies for energy boosting supplements or protein supplements or health drinks during the course of the study.\n9. Subjects willing to refrain from drinking coffee or caffeinated drinks or beverages during the study.\n\nExclusion Criteria:\n\n1. Subjects who are resistance trained or undergoing resistance training.\n2. Subjects with blood pressure more than or equal to 140\u002F90 mmHg, fasting plasma glucose more than 125 mg\u002FdL and abnormal ECG.\n3. Subjects underwent treatment for COVID-19 within last 3 months or tested positive during the study will be excluded.\n4. Evidence or history of musculoskeletal, respiratory, haematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, neurologic diseases, malignancies.\n5. Subjects diagnosed with sleep apnea or related disorders.\n6. Subjects consuming medications that can interfere with muscle mass such as corticosteroids, testosterone replacement or anabolic drugs.\n7. History of psychiatric disorder that may impair the ability of subjects to provide written informed consent.\n8. Subjects consuming alcohol (more than 3 standard drinks per week) or smokers ( more than 3 cigarettes per day).\n9. Subjects who consume recreational drugs (such as cocaine, methamphetamine, marijuana, etc.) or chewable tobacco products.\n10. Subjects under medications including anti-hypertensives, antidepressants, anticholinergics, inhaled beta agonists, anti-hyperlipidemics, psychotropics etc.\n11. Subjects using any centrally acting anorectic agents, drugs that inhibit the absorption of nutrients and endocannabinoid neuromodulators during the two weeks prior to enrolment into the study.\n12. Subjects who underwent major surgical procedures in last 6 months.\n13. Subject with HIV positive or history of any other STDs.\n14. Subject has participated in a clinical study within the last 30 days prior to recruitment or concurrently participating in another study\n\n    \\-","MALE","36 Years","50 Years",{"count":94,"type":22},120,[25],"The Purpose of the study is to evaluate the efficacy of LN18178 in improving muscle strength, aerobic capacity and body composition in healthy young males.",[98,31,99],"Muscle Strength Recovery","Healthy Human Volunteers","2025-07-29",{"date":102,"type":38},"2025-07-30",{"date":104,"type":22},"2025-08-04",{"date":106,"type":22},"2026-01-15",{"name":108,"class":45},"GENCOR Lifestage Solutions"]