[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"enhanced-recovery-after-surgery-eras-protocol\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:enhanced-recovery-after-surgery-eras-protocol":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,41,66,97,123,150,181],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100638297","effectiveness-of-enhanced-recovery-after-surgery-eras-protocols-for-arthroscopic-anterior-cruciate-ligament-reconstruction-in-an-ambulatory-surgery-setting-100638297",false,"NCT07602231","Effectiveness of Enhanced Recovery After Surgery (ERAS) Protocols for Arthroscopic Anterior Cruciate Ligament Reconstruction in an Ambulatory Surgery Setting","Evaluation of Clinical Outcomes and Feasibility of Enhanced Recovery After Surgery (ERAS) Protocols for Arthroscopic Anterior Cruciate Ligament Reconstruction in an Ambulatory Surgery Setting: A Non-randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of anterior cruciate ligament (ACL) rupture with indication for primary arthroscopic reconstruction\n* Voluntary agreement to participate in the study and signing of the informed consent form\n\nExclusion Criteria:\n\n* Patients with concomitant knee pathologies requiring additional surgical procedures in the same session\n* Presence of contraindications for ambulatory (day) surgery\n* Failure to adhere to the scheduled follow-up visits","ALL","18 Years",{"count":19,"type":20},115,"ESTIMATED","INTERVENTIONAL",[23],"NA","The anterior cruciate ligament (ACL) is a critical component for maintaining knee stability by resisting anterior tibial translation and internal rotation. ACL rupture is one of the most common orthopedic injuries, with an estimated incidence of 70 cases per 100,000 people annually. Since its inception, arthroscopic anterior cruciate ligament reconstruction (AACLR) has proven to be the gold standard, providing excellent outcomes in terms of graft longevity, return to sports, and patient satisfaction. Modern medical trends are shifting toward day-surgery protocols, where patients are discharged within 24 hours without an overnight stay. This model is identified as a major factor in enhancing the quality of postoperative recovery and patient satisfaction.\n\nThe Enhanced Recovery After Surgery (ERAS) program utilizes evidence-based multimodal interventions to reduce surgical stress and accelerate functional recovery. While day-surgery for AACLR has been proven feasible globally, its implementation in Vietnam remains limited due to systemic barriers. At the University Medical Center Ho Chi Minh City, although ERAS has been applied since 2022, the average length of stay for AACLR is 2.57 days, indicating significant room for optimization. This study aims to evaluate the current compliance with ERAS and the effectiveness of fully implementing these protocols to enable a day-surgery model.\n\nThe research is designed in two phases, including a descriptive cohort and a clinical intervention. The intervention focuses on 06 core ERAS measures:\n\n* Comprehensive preoperative counseling and education.\n* Reducing preoperative fasting by using Maltodextrin 2 hours before surgery.\n* Standardized anesthesia combined with local infiltration analgesia (LIA).\n* Multimodal analgesia to minimize opioid consumption.\n* Early drainage removal within 6-8 hours postoperatively.\n* Immediate postoperative rehabilitation starting in the recovery unit. Effectiveness will be measured through various outcomes: the quality of early recovery via the QoR-15 score, mechanical knee function via the Lysholm Knee Scoring Scale (LKSS), and health-related quality of life via the EQ-5D-5L. Furthermore, a cost-effectiveness analysis (CEA) will be conducted using the Incremental Cost-Effectiveness Ratio (ICER). The study expects to demonstrate that strict ERAS adherence makes day-surgery AACLR feasible, reduces hospital-acquired infections, optimizes operating room productivity, and lessens the financial burden on both patients and the healthcare system.",[26,27,28],"Anterior Cruciate Ligament Rupture","Enhanced Recovery After Surgery (ERAS) Protocol","Ambulatory Surgery","NOT_YET_RECRUITING","2026-05-22",{"date":32,"type":33},"2026-05-28","ACTUAL",{"date":35,"type":20},"2026-05-18",{"date":37,"type":20},"2027-06-30",{"name":39,"class":40},"University Medical Center Ho Chi Minh City (UMC)","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":49,"minAge":17,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":65},"100636313","enhanced-recovery-after-surgery-in-hysterectomy-patients-100636313","NCT07564063","Enhanced Recovery After Surgery in Hysterectomy Patients","Effectiveness of Enhanced Recovery After Surgery (ERAS) Protocols in Hysterectomy Patients. A Prospective,Randomized Controlled Clinical Trial.","ERAS","Inclusion Criteria:\n\n* Women aged 18-70 years.\n* Undergoing elective total hysterectomy for benign or early stage malignant gynacological conditions .\n* ASA ( American Society of Anesthesiologists ) physical status I-II.\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* Emergency hysterectomy\n* Advanced malignant requiring extensive debulking\n* Known bowel disease or previous bowel surgery ( crohn's disease , bowel obstruction )\n* Significant cognitive impairment or psychiatric illness\n* Inability to follow ERAS protocol (e.g., cognitive impairment)\n* Refusal to participate","FEMALE","70 Years",{"count":52,"type":20},78,[23],"This prospective randomized controlled clinical trial aims to evaluate the effectiveness of Enhanced Recovery After Surgery (ERAS) protocols in patients undergoing elective hysterectomy. ERAS is an evidence-based perioperative approach designed to reduce surgical stress, accelerate recovery, and improve clinical outcomes. Participants will be randomized to receive either ERAS-based care or conventional perioperative management. The study will assess whether ERAS implementation reduces hospital stay and improves postoperative recovery without increasing complications.",[27],"2026-04-26",{"date":58,"type":33},"2026-05-04",{"date":60,"type":20},"2026-06-01",{"date":62,"type":20},"2027-01-01",{"name":64,"class":40},"Cairo University",1,{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":74,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":78,"conditions":79,"keywords":84,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":96},"100623395","pre-operative-risk-assessment-combined-with-targeted-intervention-in-the-chinese-elderly-with-spine-surgery-ii-100623395","NCT07396077","Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery II","Multimodal Physiological Reserve Optimizing Prehabilitation Program (PHYSIO-Prehab) in the Chinese Elderly With Spine Surgery","PRACTICE-2","Inclusion Criteria:\n\n1. Aged ≥75 years at the time of screening\n2. Voluntarily sign the informed consent form\n3. Clinically diagnosed with degenerative lumbar spinal disorders with duration of symptoms \\>6 months\n4. Requiring elective lumbar fusion surgery (single-level or multi-level, open or minimally invasive approach)\n5. No severe cognitive impairment (Mini-Mental State Examination score \\> 9)\n6. Scheduled to undergo surgery within 6-8 weeks after screening (allowing completion of the 6-week prehabilitation program)\n\nExclusion Criteria:\n\n1. Scheduled to undergo other emergency surgery or day surgery\n2. Urgent medical conditions requiring priority management before spinal surgery\n3. With spinal disorders other than degenerative diseases (spinal fracture, tumor, metastasis, infection, ankylosing spondylitis, scoliosis with Cobb angle \\>40°)\n4. With contraindications to prehabilitation exercise (New York Heart Association Class IV heart failure, unstable angina, uncontrolled hypertension \\[systolic BP ≥180 mmHg or diastolic BP ≥110 mmHg despite medication\\])\n5. With severe functional disability for other disorders or long-term bedridden status unable to perform basic physical activities\n6. With allergy or intolerance to nutritional supplements used in the prehabilitation program\n7. Participating in another clinical trial involving prehabilitation, perioperative intervention, or spinal surgery within 3 months before screening","75 Years",{"count":76,"type":20},248,[23],"This multicenter, parallel-group, assessor-blinded randomized controlled trial will enroll 248 adults aged ≥75 years with degenerative lumbar spinal diseases scheduled for elective lumbar fusion surgery, and they will be randomized 1:1 into the intervention and usual care groups. The intervention group will receive a 6-week PHYSIO-Prehab multimodal prehabilitation program, including multicomponent exercise, nutritional intervention, comorbidity optimization, and cognitive prehabilitation with brain protection strategies. The control group will receive standard health education provided via a manual, and both groups will receive consistent perioperative Enhanced Recovery After Surgery care. The primary outcome will be the change in Barthel Index (a tool for assessing independence in activities of daily living) from baseline to 30 days postoperatively; secondary outcomes will include pain scores, disability, patient satisfaction, and the 30-day postoperative Comprehensive Complication Index. The trial will initiate recruitment in April 2026 and conclude in December 2027, aiming to evaluate the feasibility and efficacy of PHYSIO-Prehab and provide high-quality evidence for patient-centered perioperative care pathways in this population.",[80,81,82,27,83],"Spine Degeneration","Lumbar Degenerative Disease","Frail Elderly","Prehabilitation",[83,47,85,86],"lumbar fusion","ADL","RECRUITING",{"date":89,"type":33},"2026-04-28",{"date":91,"type":33},"2026-04-15",{"date":93,"type":20},"2027-12-30",{"name":95,"class":40},"Xuanwu Hospital, Beijing",4,{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":16,"minAge":104,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":21,"phases":108,"briefSummary":109,"conditions":110,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":65},"100630028","impact-of-different-fasting-strategies-on-gastric-ultrasound-and-anxiety-levels-in-children-100630028","NCT07482345","Impact of Different Fasting Strategies on Gastric Ultrasound and Anxiety Levels in Children","Impact of Three Different Preoperative Fasting Strategies on Gastric Ultrasound Findings and Anxiety Levels in Children Undergoing Inguinoscrotal Surgery: A Prospective Randomized Trial","Inclusion Criteria:\n\n* Patients scheduled to undergo elective surgery under general anesthesia for circumcision, undescended testis, inguinal hernia, and\u002For hypospadias (inguinoscrotal surgery)\n* Patients with an ASA physical status classification of I-II\n* Patients able to tolerate oral intake in the preoperative period and comply with the assigned fasting protocol\n* Written informed consent obtained from parents or legal guardians\n\nExclusion Criteria:\n\n* Patients with ASA physical status III or higher\n* Patients requiring emergency surgery\n* History of gastroesophageal reflux disease, gastrointestinal motility disorders, or metabolic\u002Fneurological diseases affecting gastric emptying\n* History of upper gastrointestinal surgery\n* Active upper respiratory tract infection or lower respiratory tract infection within the previous 2-4 weeks\n* Severe pulmonary disease, including uncontrolled or moderate-to-severe persistent asthma, bronchopulmonary dysplasia, cystic fibrosis, interstitial lung disease, or other chronic lung diseases\n* Diabetes mellitus or endocrine\u002Fmetabolic disorders that may affect perioperative glucose metabolism\n* Obese patients with high aspiration risk (\\>95th percentile for age)\n* Cognitive or communication impairments that may interfere with compliance with the study protocol\n* Grade 2 or Grade 3 gastric fullness detected on preoperative gastric ultrasonography\n* Lack of written informed consent from parents or legal guardians for participation in the study","2 Years","12 Years",{"count":107,"type":20},90,[23],"Children who undergo surgery are usually asked to stop eating and drinking for several hours before anesthesia to reduce the risk of stomach contents entering the lungs. However, long fasting times may cause discomfort, dehydration, low blood sugar, and increased anxiety in children. Recent guidelines suggest that clear liquids can safely be allowed closer to the time of surgery, and some enhanced recovery protocols even recommend giving carbohydrate-containing drinks before anesthesia.\n\nThis study will compare three different preoperative fasting approaches in children undergoing elective inguinoscrotal surgery: traditional fasting, preoperative carbohydrate drinks, and the \"Sip-Til-Send\" approach, which allows clear fluids until the child is called to the operating room.\n\nThe children's anxiety levels will be evaluated before surgery using a validated anxiety scale and assess stomach content and volume using gastric ultrasound. The secondary outcomes such as nausea, vomiting, pain, emergence delirium, and blood glucose levels will be evaluated.\n\nThe results may help determine safer and more comfortable fasting strategies for children undergoing surgery.",[111,27,112],"Preoperative Fasting","Pediatric Surgery","2026-03-19",{"date":115,"type":33},"2026-03-23",{"date":117,"type":20},"2026-03-25",{"date":119,"type":20},"2027-04-30",{"name":121,"class":122},"Bursa City Hospital","OTHER_GOV",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":130,"sex":49,"minAge":131,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":21,"phases":135,"briefSummary":137,"conditions":138,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":65},"100606646","phase-4-erector-spinae-block-in-reducing-peri-operative-opioid-consumption-in-total-abdominal-hystrectomy-100606646","NCT07178262","Erector Spinae Block in Reducing Peri-operative Opioid Consumption in Total Abdominal Hystrectomy","Opioid Sparing Effect of Erector Spinae Block in Patients Undergoing Total Abdominal Hysterectomy; A Randomized Control Trial","Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) class: I, II and III .\n* Elective Hysterectomy under General Anesthesia.\n\nExclusion Criteria:\n\n* Lack of consent\n* Body mass index \\>35 kg\u002Fm2\n* Allergic to study medicine\n* Opioid abuse or misuse disorder\n* Chronic pain",true,"16 Years","80 Years",{"count":134,"type":20},60,[136],"PHASE4","Hystrectomy is a surgical procedure that involves removal of uterus from the body of patient using a lower abdominal incision. This is an extremely painful procedure which causes discomfort and greatly increases opioids consumption in the peri-operative period. This can be reduced by using nerve blocks such as Erector spinae plane block.",[139,27,140],"Erector Spinae Block","Opioid","2025-09-12",{"date":143,"type":33},"2025-09-17",{"date":145,"type":33},"2025-08-01",{"date":147,"type":20},"2025-10-30",{"name":149,"class":40},"Kulsoom International Hospital",{"id":151,"slug":152,"hasResults":11,"nctId":153,"briefTitle":154,"officialTitle":155,"acronym":4,"eligibilityCriteria":156,"healthyVolunteers":11,"sex":157,"minAge":158,"maxAge":159,"enrollmentInfo":160,"targetDuration":4,"studyType":21,"phases":162,"briefSummary":163,"conditions":164,"keywords":168,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":65},"100483571","enhanced-recovery-after-surgery-eras-pathway-in-patients-undergoing-robot-assisted-laparoscopic-radical-prostatectomy-100483571","NCT05576766","Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy","Impact of Enhanced Recovery After Surgery (ERAS) Pathway on Outcomes in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 60 years or over but below 90 years.\n* Scheduled to undergo robot-assisted laparoscopic radical prostatectomy (RARP) for prostate cancer.\n* Agree to participate in this study and give written informed consent.\n\nExclusion Criteria:\n\n* Scheduled to undergo combined surgery, including RARP combined with pelvic lymph node dissection or other procedures.\n* American Society of Anesthesiologists (ASA) physical classification ≥IV.\n* Inability to receive preoperative aerobic exercise because of severe cardiovascular disease, motor system diseases (arthritis, lumbar vertebrae disease), or central nervous system diseases (epilepsy, parkinsonism).\n* Inability to communicate in the preoperative period because of profound dementia, deafness, or language barriers.\n* History of schizophrenia, anxiety or depressive disorders, or other mental disorders.","MALE","60 Years","90 Years",{"count":161,"type":20},54,[23],"Prostate cancer ranks second among all malignances in men and has become a significant threat to men's health. Robot-assisted laparoscopic radical prostatectomy (RARP) has become a standard treatment for prostate cancer. How to improve recovery following RARP surgery is worth investigating. The enhanced recovery after surgery (ERAS) pathway involves a series of evidence-based procedures. It is aimed to reduce the systemic stress response to surgery and shorten the length of hospital stay. This randomized trial aims to investigate the impact of Enhanced Recovery After Surgery (ERAS) Pathway on early outcomes after RARP surgery.",[165,166,27,83,167],"Prostate Cancer","Robot-Assisted Laparoscopic Radical Prostatectomy","Length of Hospital Stay",[165,166,169,170,47,83,171],"RARP","Enhanced Recovery After Surgery","Length of hospital stay","2025-08-15",{"date":174,"type":33},"2025-08-21",{"date":176,"type":20},"2025-09",{"date":178,"type":20},"2026-12",{"name":180,"class":40},"Peking University First Hospital",{"id":182,"slug":183,"hasResults":11,"nctId":184,"briefTitle":185,"officialTitle":186,"acronym":4,"eligibilityCriteria":187,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":188,"enrollmentInfo":189,"targetDuration":4,"studyType":21,"phases":191,"briefSummary":192,"conditions":193,"keywords":197,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":65},"100577842","effect-of-enhanced-recovery-after-surgery-for-benign-anorectal-conditions-100577842","NCT06803550","Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions","Effect of Enhanced Recovery After Surgery in Reducing the Incidence of Postoperative Urinary Retention After Surgery for Benign Anorectal Conditions: a Randomized Controlled Trial","Inclusion Criteria:\n\n* both sexes\n* aged between 18 and 65 years old\n* presented with benign anorectal conditions including chronic anal fissure, hemorrhoids, and fistula-in-ano will be eligible for the study\n\nExclusion Criteria:\n\n* younger than 18\n* older than 65 years old\n* pregnant female\n* history of relevant urological diagnosis (benign prostatic hyperplasia\u002Fprostate cancer\u002Furethral stricture\u002Fbladder neck stenosis\u002Fdetrusor underactivity\u002Fdetrusor overactivity)\n* history of relevant urological procedure (radical prostatectomy\u002F transurethral prostatectomy\u002Fbladder neck or urethral surgery\u002Fpelvic radiotherapy)\n* use of permanent urinary catheter\n* intraoperative urological procedures\n* with any form of urinary diversion\n* severe cognitive impairment\n* who undergo other anorectal procedures","65 Years",{"count":190,"type":20},100,[23],"This study aims to assess the role of Enhanced recovery after surgery(ERAS) protocol in reducing postoperative urine retention (POUR) after surgery for benign anorectal conditions.",[194,195,196,27],"Anal Fistula","Anal Fissure Chronic","Haemorrhoid",[47,198,199,200,201,202],"Postoperative urinary retention","Benign anorectal conditions","Anal fistula","Anal fissure","Haemorrhoids","2025-01-30",{"date":205,"type":33},"2025-02-03",{"date":207,"type":33},"2024-12-17",{"date":209,"type":20},"2025-06-30",{"name":211,"class":40},"Mansoura University"]