[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"enhanced-recovery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:enhanced-recovery":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100628665","crp-point-of-care-testing-trajectory-a-predictive-factor-for-anastomotic-leak-in-elective-colorectal-surgery-100628665",false,"NCT07464600","CRP Point-of-care Testing Trajectory, a Predictive Factor for Anastomotic Leak in Elective Colorectal Surgery","CRP Point-of-care Testing Trajectory, a Predictive Factor for Anastomotic Leak in Elective Colorectal Surgery? A Key to Early Rehabilitation?","CRP","Inclusion Criteria:\n\n* Patients undergoing elective (non-emergency) colorectal surgery, regardless of the approach (laparotomy, laparoscopy, robotic) and whether there is a protective ileostomy.\n\nExclusion Criteria:\n\n* No anastomosis\n* Urgent surgery\n* Pregnancy or breast-feeding\n* Patients under guardianship or trusteeship\n* Minor patients","ALL","18 Years",{"count":20,"type":21},500,"ESTIMATED","INTERVENTIONAL",[24],"NA","In colorectal surgery, one of the most feared complications is anastomotic leak (AL). To limit the consequences of AL, it must be diagnosed as early as possible, before it becomes symptomatic. Digestive surgeons use a variety of pre-, per- and post-operative techniques to reduce the rate of anastomotic fistula, but the risk persists, with a rate of 7% reported in the literature. It has been shown that the value of CRP between D1 and D5 correlates with the risk of AL, and that the trajectory between two consecutive days (D1 to D5 post-op) is the most discriminating element in predicting the risk of AF. This assay requires repeated intravenous sampling, which is the opposite of simplifying care. CRP point-of-care testing (POCT) is used in clinical practice, notably in pediatrics and outpatient medicine (in children and adults) to help prescribe probabilistic antibiotic therapy, as the instantaneousness of the result has an impact on patient management. For the diagnosis of AL, CRP POCT assessment could reduce the number of blood samples taken, shorten the time between sampling and medical management in cases of suspected AL, and thus improve the patient's post-operative experience.",[27,28,29,30,31],"Colorectal Surgery","Enhanced Recovery","CRP Point-of-care Testing Trajectory","Post-operative Complication","Anastomotic Leak",[33,34,35,36,37],"colorectal surgery","enhanced recovery","CRP point-of-care testing trajectory","post-operative complication","anastomotic leak","RECRUITING","2026-03-06",{"date":41,"type":42},"2026-03-11","ACTUAL",{"date":44,"type":42},"2025-09-17",{"date":46,"type":21},"2029-02",{"name":48,"class":49},"Centre Hospitalier Universitaire, Amiens","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":72,"leadSponsor":74,"locationsCount":50},"100625040","transversus-thoracic-muscle-plane-block-versus-pectointercostal-fascial-block-for-enhanced-recovery-after-cardiac-surgery-100625040","NCT07417462","Transversus Thoracic Muscle Plane Block Versus Pectointercostal Fascial Block for Enhanced Recovery After Cardiac Surgery","Transversus Thoracic Muscle Plane Block Versus Pectointercostal Fascial Block for Enhanced Recovery After Cardiac Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 40 to 60 years.\n* Both sexes.\n* American Society of Anesthesiology (ASA) physical status II-III.\n* Body mass index (BMI) \\\u003C 35 kg\u002Fm2.\n* Underwent cardiac surgery (coronary artery bypass graft surgery with median sternotomy).\n\nExclusion Criteria:\n\n* Valve replacement procedures.\n* Emergency operations.\n* Redo surgeries.\n* Minimally invasive approaches.\n* The presence of psychiatric disorders.\n* Cognitive impairment preventing accurate assessment using the verbal numerical rating scale (NRS).\n* Known hypersensitivity or a history of allergy to local anesthetics.\n* Had severe major organ dysfunction.\n* Left ventricular ejection fraction below 30%.\n* Pregnancy or breastfeeding.","40 Years","60 Years",{"count":61,"type":21},90,[24],"This work aims to assess the analgesic efficacies of transversus thoracic muscle plane block (TTPB) and transversus thoracic muscle plane block (TTPB) for open cardiac surgeries",[65,66,28,67],"Transversus Thoracic Muscle Plane Block","Pecto-intercostal Fascial Block","Cardiac Surgery","2026-02-18",{"date":70,"type":42},"2026-02-19",{"date":68,"type":42},{"date":73,"type":21},"2026-06-01",{"name":75,"class":49},"Assiut University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":83,"maxAge":59,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":50},"100590337","phase-4-lidocaine-infusion-versus-magnesium-infusion-in-decreasing-fentanyl-requirements-in-endoscopic-sinus-surgeries-100590337","NCT06966102","Lidocaine Infusion Versus Magnesium Infusion in Decreasing Fentanyl Requirements in Endoscopic Sinus Surgeries","Evaluating the Effect of Lidocaine Infusion Versus Magnesium Sulfate Infusion on Decreasing Total Fentanyl Requirements in Patients Undergoing Functional Endoscopic Sinus Surgeries: a Randomized Controlled Study","Inclusion Criteria:\n\n* Age from 21 to 60 years.\n* Both genders.\n* American society of Anesthesiologist (ASA) physical status I-II\n* Scheduled for functional endoscopic sinus surgery under general anesthesia.\n\nExclusion Criteria:\n\n* Patients with prolonged QT interval.\n* Patients with renal disease.\n* Patients with a history of allergy to lidocaine or magnesium sulfate.\n* American Society of Anesthesiologists class higher than II.\n* Patient refusal","21 Years",{"count":85,"type":21},156,[87],"PHASE4","Enhanced recovery after ear, nose and throat surgery is based on multimodal and multidisciplinary perioperative interventions to decrease postoperative pain. Functional endoscopic sinus surgery is a surgical management for chronic rhinosinusitis. Although a common procedure, there is a lack of knowledge about perioperative pain and specific pain management after such a procedure. Most of recommendations given in guidelines for postoperative pain management in nasal surgery and sinus surgery are subsumed under head and neck surgery. Head and neck surgery is a wide field covering widely variable surgical procedures. So, postoperative pain management guidelines may not meet the requirements for pain management during and after endoscopic sinus surgery.\n\nVarious medications have been used to improve the surgical field and postoperative pain including intravenous clonidine, dexmedetomidine, lidocaine, and magnesium.\n\nLidocaine has been used considering its analgesic, immuno-modulating, and anti-inflammatory properties. The opioid sparing effect of lidocaine is supported by a high level of evidence. The effectiveness of lidocaine infusion in obtaining reduction of postoperative pain, gastrointestinal recovery time, postoperative nausea and vomiting, and shortening the hospital length of stay, was demonstrated principally in major gastro-intestinal surgery.\n\nMagnesium sulfate is a good option in multimodal analgesia, as it stabilizes the cell membrane and intracytoplasmic organelles by mediating the activation of Na+-K+ ATPase and Ca++ ATPase enzymes, which have an important role in transmembrane ion exchange during the depolarization and repolarization phases. Moreover, magnesium inhibits the release of norepinephrine by blocking the N-type Ca++ channels at nerve endings.\n\nMany studies were designed to prove the role of the analgesic effect of lidocaine and magnesium infusion. However, this is the first randomized controlled study to assess the effect of lidocaine infusion versus magnesium sulphate infusion on decreasing total fentanyl requirements in patients undergoing functional endoscopic sinus surgery.\n\nThis randomized controlled trial was designed to compare the efficacy of lidocaine hydrochloride infusion versus magnesium sulphate infusion in controlling perioperative pain in patients undergoing functional endoscopic sinus surgery.",[28,90,91,92,93],"Functional Endoscopic Sinus Surgery","Lidocaine","Magnesium Sulphate","Perioperative Pain","NOT_YET_RECRUITING","2025-05-03",{"date":97,"type":42},"2025-05-11",{"date":99,"type":21},"2025-05-10",{"date":101,"type":21},"2025-07-30",{"name":103,"class":49},"Cairo University"]