[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"enteral-nutrition-feeding\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:enteral-nutrition-feeding":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,43,78,109,137],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100633009","predictive-value-of-gastrointestinal-blood-flow-for-enteral-nutrition-intolerance-in-critically-ill-patients-100633009",false,"NCT07521111","Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients","Study on the Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients","Inclusion Criteria:\n\n* Age \\> 18 years old.\n* Expected duration of enteral nutrition support \\> 7 days.\n* Patients or their legal representatives sign the informed consent form.\n\nExclusion Criteria:\n\n* History of major gastrointestinal surgery such as subtotal gastrectomy and gastrointestinal anastomosis.\n* Contraindications to abdominal point-of-care ultrasound (POCUS) examination (e.g., recent large-area abdominal burns, dressings blocking movement, open abdomen).\n* Presence of severe gastrointestinal diseases such as gastroparesis, intestinal obstruction, digestive tract perforation, and gastrointestinal bleeding upon admission.\n* Presence of severe peripheral vascular disease or valvular heart disease.\n* Pregnant or lactating women.","ALL","18 Years",{"count":19,"type":20},500,"ESTIMATED","28 Days","OBSERVATIONAL","This study aims to explore the correlation between gastrointestinal blood flow and the incidence of enteral nutrition intolerance (ENI) and its symptoms in critically ill patients, construct and compare predictive models including blood flow parameters, and evaluate their incremental predictive value.",[25,26,27,28,29],"Critical Illness","Enteral Nutrition Intolerance","Enteral Nutrition Feeding","Prediction Models","Machine Learning","RECRUITING","2026-04-02",{"date":33,"type":34},"2026-04-09","ACTUAL",{"date":36,"type":34},"2026-01-25",{"date":38,"type":20},"2027-06-30",{"name":40,"class":41},"Ruijin Hospital","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":42},"100622411","we-need-to-feed-facilitating-enteral-education-for-discharge-100622411","NCT07383272","We Need to FEED: Facilitating Enteral Education for Discharge","We Need to F.E.E.D.: Facilitating Enteral Education for Discharge - Improving the Quality of Discharge for Pediatric Patients With Enteral Tubes","WeNeed2FEED","Inclusion Criteria:\n\n* Patients must be within the age range of 0 to 17 years.\n* Patients who have recently had an enteral feeding tube placed (G-tube, J-tube, GJ-tube, or NG-tube).\n* The patient must be hospitalized at the time of the study and scheduled for discharge within the study period (before discharge).\n* A legal guardian must be available to participate in the study, complete questionnaires, and engage in the educational sessions.\n* Both the pediatric patient and their caregiver must be willing to participate in the study, including completing surveys and receiving educational materials.\n\nExclusion Criteria:\n\n* Patients who have had an enteral tube (G-tube, J-tube, GJ-tube, or NG-tube) for more than a short period (e.g., those who have had tubes in place for more than 3 months) may be excluded, as the study is focused on newly placed feeding tubes.\n* Patients aged 18 years or older are excluded from the study, as the project targets pediatric patients specifically.\n* If the caregiver (or the child, where applicable) has significant cognitive or language barriers that would prevent them from understanding the educational content or completing the surveys, they may be excluded.\n* Families who do not speak English may be excluded.\n* Patients with significant comorbidities or unstable clinical conditions that would make participation in the discharge education protocol impractical will be excluded. This includes, but is not limited to, patients with severe respiratory failure requiring nitric oxide therapy, hemodynamic instability requiring blood pressure medications (e.g., vasopressors), or other acute medical conditions requiring active intensive care. Patients who are stable and preparing for discharge, even after a prolonged NICU or PICU stay, will not be excluded.\n* Only legal guardian can enroll child.\n* Patients whose caregivers are unable or unwilling to adhere to study protocols (e.g., participating in follow-up assessments or completing questionnaires) may be excluded to ensure consistency and reliable data collection.","17 Years",{"count":53,"type":20},20,"INTERVENTIONAL",[56],"NA","Aim: We need to FEED (Facilitating Enteral Education for Discharge) project aims to streamline and enhance the discharge process for pediatric patients with enteral nutrition (including G-tubes, J-tubes, GJ-tubes, and NG-tubes) and ultimately create enteral discharge protocol. The aim of the study is to describe the effectiveness of the discharge education program for children with enteral tubes on caregiver knowledge and determine the impact of the program on unplanned ER, Urgent care or clinic visits. By ensuring that all necessary supplies, orders, and follow-up appointments are in place prior to discharge, and by providing comprehensive education and support to parents, the project seeks to improve patient outcomes, reduce healthcare utilization, enhance coordination and communication among healthcare providers.",[27],[60,61,62,63,64,65,66,67],"education","feeding tube","g tube","ng tube","gj tube","parent education","pediatrics","patient education","NOT_YET_RECRUITING","2026-03-24",{"date":71,"type":34},"2026-03-25",{"date":73,"type":20},"2026-04-01",{"date":75,"type":20},"2028-05-01",{"name":77,"class":41},"University of Illinois at Chicago",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":54,"phases":87,"briefSummary":88,"conditions":89,"keywords":93,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":42},"100606520","the-pre-vail-study-100606520","NCT07176624","The PRE-VAIL Study","The Effect of Reducing Enteral Nutrition Before Prone Positioning on Clinical Outcomes in Mechanically Ventilated ARDS Patients: A Multicenter Randomized Controlled Trial (The PRE-VAIL Study)","Inclusion Criteria:\n\n* Age ≥18 years old\n* Within 24 hours of admission to the ICU, one or more organ systems have failed (the Sequential Organ Failure Assessment (SOFA) score of any single organ system is ≥2)\n* Meet the diagnostic criteria for moderate\u002Fsevere ARDS (even after optimizing the ventilation Settings, the oxygenation index is still \\\u003C 150mmHg and PEEP is still ≥5 cm H2O)\n* It is expected to stay in the ICU for more than 48 hours\n\nExclusion Criteria:\n\n* There are contraindications for the prone position\n* There are contraindications for EN, preventing the initiation of early EN (≤48 hours)\n* Expected to die within 48 hours\n* Pregnancy",{"count":86,"type":20},259,[56],"During the prone position, there may be an increase in intragastric pressure. The investigators focus on a scientific question: Whether reducing enteral nutrition before the prone position will benefit patients with severe mechanically ventilated acute respiratory distress syndrome (ARDS).\n\nThe experimental group had the enteral nutrition dose reduced before the prone position, while the control group did not have the enteral nutrition dose reduced",[90,91,27,92],"ARDS (Moderate or Severe)","Prone Position","Intensive Care Unit (ICU) Admission",[94,95,96,97,98,99],"ARDS","Mechanical ventilation","Prone position","Enteral nutrition","Gastric retention","Clinical outcome","2026-02-05",{"date":102,"type":34},"2026-02-09",{"date":104,"type":34},"2025-09-14",{"date":106,"type":20},"2028-02-20",{"name":108,"class":41},"The First Hospital of Jilin University",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":4,"eligibilityCriteria":115,"healthyVolunteers":11,"sex":16,"minAge":116,"maxAge":117,"enrollmentInfo":118,"targetDuration":4,"studyType":54,"phases":120,"briefSummary":121,"conditions":122,"keywords":125,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":42},"100616547","stepwise-enteral-nutritional-algorithm-and-patient-outcomes-in-pediatric-intensive-care-units-100616547","NCT07307027","Stepwise Enteral Nutritional Algorithm and Patient Outcomes in Pediatric Intensive Care Units","Could a Stepwise Enteral Nutritional Algorithm Affect Patient's Outcome in Pediatric Intensive Care Units? An Interventional Study","Inclusion Criteria:\n\n* Critically ill infants and children admitted to the Pediatric Intensive Care Units.\n* Age range from 1 month to 16 years (specifically males up to 14 years and females up to 16 years).\n\nExclusion Criteria:\n\n* Patients who are discharged or died within 24 hours of admission.\n* Patients with acute pancreatitis.\n* Patients with esophageal perforation.\n* Patients with a known metabolic disorder.\n* Patients requiring a ketogenic diet.\n* Patients with Short Bowel Syndrome.","1 Month","16 Years",{"count":119,"type":20},80,[56],"The aim of the study to evaluate the effectiveness and patient's outcome after implementing enteral nutrition algorithm designed to achieve optimal enteral nutrition delivery in the pediatric intensive care unit and to evaluate the effect of implementing this protocol on critically ill patient's individual's outcome.",[123,27,124],"Enteral Nutrition","Enteral Nutrition Intolerance in Critically Ill Patients",[126,127],"enteral nutrition in critically ill","EN","2026-01-14",{"date":130,"type":34},"2026-01-16",{"date":132,"type":34},"2024-12-01",{"date":134,"type":20},"2026-03-03",{"name":136,"class":41},"Ain Shams University",{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":4,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":144,"enrollmentInfo":145,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":146,"conditions":147,"keywords":151,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":42},"100593092","correlation-study-between-sma-blood-flow-reactivity-and-acute-gastrointestinal-injury-in-critically-ill-patients-100593092","NCT07001943","Correlation Study Between SMA Blood Flow Reactivity and Acute Gastrointestinal Injury in Critically Ill Patients","Correlation Study Between SMA Blood Flow Reactivity and Acute Gastrointestinal Functional Injury in Critically Ill Patients","Inclusion Criteria:\n\n* Adults aged ≥18 years and ≤80 years.\n* Admitted to the study with a expected stay of more than 72 hours.\n* Require initiation of enteral nutrition support.\n\nExclusion Criteria:\n\n* Pre-existing severe gastrointestinal diseases.\n* Patients with gastrointestinal bleeding.\n* Patients with bowel obstruction.\n* Pregnant or lactating women.\n* Patients with contraindications to bedside Doppler ultrasound.","80 Years",{"count":119,"type":20},"This study aims to address the challenges of enteral nutrition support in critically ill ICU patients with varying gastrointestinal function. We'll use bedside Doppler ultrasound to monitor superior mesenteric artery (SMA) blood flow changes post - feeding, exploring its correlation with Acute Gastrointestinal Injury (AGI) and other hemodynamic indicators. Our goals are to identify the patterns of SMA blood flow changes, establish a predictive model linking SMA blood flow reactivity to AGI risk, and propose individualized enteral nutrition strategies based on intestinal hemodynamics. Through this innovative approach, we hope to enhance the safety of enteral nutrition, reduce AGI incidence, and improve patient outcomes.",[148,25,27,149,150],"Intestinal Ischemia","Hemodynamics","Ultrasonography, Doppler",[123,25,148,149],"2025-08-28",{"date":154,"type":34},"2025-09-05",{"date":156,"type":34},"2025-06-01",{"date":158,"type":20},"2026-07-01",{"name":160,"class":41},"Peking Union Medical College Hospital"]