[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"eosinophilic-gastrointestinal-disorders-egids\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:eosinophilic-gastrointestinal-disorders-egids":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,39],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100612765","dupilumab-therapy-for-egids-100612765",false,"NCT07257835","Dupilumab Therapy for EGIDs","Dupilumab Therapy for Refractory Eosinophilic Gastrointestinal Disorders in Children","Inclusion Criteria:\n\n* Clinical diagnosis of Refractory Peptic Ulcers\n* with Refractory Eosinophilic Gastrointestinal Disorders\n\nExclusion Criteria:\n\n* with Active Helicobacter pylori infection at present.\n* with Inflammatory bowel disease\n* with Parasite infection\n* with Cancer","ALL","1 Year","18 Years",{"count":20,"type":21},20,"ESTIMATED","OBSERVATIONAL","This is a single-center observational study to investigate the efficacy and tolerability of dupilumab in children with refractory eosinophilic gastrointestinal disorders.",[25],"Eosinophilic Gastrointestinal Disorders (EGIDs)","RECRUITING","2025-11-26",{"date":29,"type":30},"2025-12-02","ACTUAL",{"date":32,"type":30},"2025-01-01",{"date":34,"type":21},"2027-12-01",{"name":36,"class":37},"Children's Hospital of Fudan University","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":47,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":50,"conditions":51,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":65},"100249239","omega-outcome-measures-in-eosinophilic-gastrointestinal-disorders-across-the-ages-100249239","NCT02523118","OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages","A Prospective, Multicenter Study to Compare and Validate Endoscopic, Histologic, Molecular, and Patient-Reported Outcomes in Pediatric and Adult Patients With Eosinophilic Esophagitis (EoE), Gastritis (EoG), Enteritis (EoN) and Colitis (EoC)","OMEGA","Inclusion Criteria:\n\n* Males or females 3 years of age and older\n* Mucosal eosinophilia:\n\nEoE ≥ 15 eosinophils\u002FHPF in the distal or proximal esophagus EoG ≥ 30 eosinophils\u002FHPF in 5 HPF\\'s in the body and\u002For antrum EoN ≥ 53 eosinophils\u002FHPF in the duodenum and\u002For ≥ 56 eosinophils\u002FHPF in the jejunum and\u002For ileum EoC ≥ 84 eosinophils\u002FHPF from the transverse or descending colon and\u002For ≥ 32 eosinophils\u002FHPF from the rectosigmoid colon or a biopsy from any colonic location with ≥ 100 eosinophils\u002FHPF\n\n\\- Presence of symptoms is required for patients who are newly diagnosed but not required for patients who were previously diagnosed.\n\nExclusion Criteria:\n\n* History of intestinal surgery other than G tube placement\n* Enrolled in a blinded investigational study at the time of the first study visit\n* Have esophageal stricture (\\<3mm)\n* Have other identifiable causes for eosinophilia (except Inflammatory Bowel Disease): infections, Gastrointestinal (GI) cancer, other GI inflammatory disease (e.g., Ulcerative Colitis or Crohn\\'s Disease)","3 Years",{"count":49,"type":21},1350,"The purpose of this observational study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EoG, EoN and EoC normally undergo endoscopy and\u002For colonoscopy where cells are collected for microscopic analysis. Treatments are then decided based on how the cells look. We are aiming to compare different tissue components such as inflammatory cell types with clinical symptoms. We want to see if scores on standard questionnaires can give us an idea how well the person is doing.",[25,52,53,54,55],"Eosinophilic Esophagitis","Eosinophilic Gastritis","Eosinophilic Gastroenteritis","Eosinophilic Colitis","2025-09-11",{"date":58,"type":30},"2025-09-12",{"date":60,"type":30},"2015-07-17",{"date":62,"type":21},"2051-01-01",{"name":64,"class":37},"Children's Hospital Medical Center, Cincinnati",19]