[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"eras\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:eras":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,18,0,[8,44,67,90,124,156,182,206,229,258,288,322,346,367,392,423,442,470],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100642644","feasibility-and-safety-of-a-pediatric-eras-protocol-for-laparoscopic-appendectomy-100642644",false,"NCT07643285","Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy","Clinical Outcomes and Institutional Integration of the ERAS (Enhanced Recovery After Surgery) Protocol in Pediatric Appendicetomies: A Mixed Methodological IDEAL (Idea, Development, Exploration, Assessment, Long-term Study) 2a Preliminary Study","Inclusion Criteria:\n\n1. Pediatric patients aged 5 to 18 years (preschool, school-age, and adolescent).\n2. Acute appendicitis without preoperative radiologic or clinical evidence of complication\u002Fperforation, who are candidates for and accept laparoscopic surgery.\n3. ASA Physical Status I (healthy) or ASA II (mild systemic disease).\n4. Family\u002Flegal guardians literate in Turkish (or the institution's primary service language) and able to comprehend the educational materials.\n5. Written informed consent from parents\u002Flegal guardians; for children of sufficient developmental maturity (generally ≥7 years), age-appropriate written assent.\n\nExclusion Criteria:\n\n1. Preoperative imaging or clinical evidence of complicated appendicitis (perforation, generalized peritonitis, intra-abdominal abscess) anticipated to require an extended procedure (anastomosis, resection, or extensive peritoneal irrigation).\n2. History of chronic pain syndrome or regular\u002Fsustained opioid use within the past 3 months.\n3. Therapeutic preoperative antibiotic treatment for an active infection (other than surgical prophylaxis).\n4. ASA III or higher; immunosuppression, progressive neurological disease, chronic inflammatory bowel disease, or other significant comorbidities likely to interfere with postoperative recovery\u002Fmobilization.\n5. Anatomic\u002Fmechanical contraindications to laparoscopy or pneumoperitoneum (e.g., prior major open abdominal surgery with suspected adhesions, abdominal wall defects).","ALL","5 Years","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","Acute appendicitis is the most common surgical emergency in children. Despite the widespread adoption of laparoscopic appendectomy, postoperative care still varies widely between institutions, with prolonged fasting, opioid-based analgesia, delayed feeding, and routine drain placement being common. Enhanced Recovery After Surgery (ERAS) is an evidence-based, multidisciplinary care pathway that has been shown in adults - and increasingly in children - to reduce length of stay, opioid consumption, and postoperative complications.\n\nThis single-center, prospective, single-arm cohort feasibility study (IDEAL Stage 2a) tests whether a comprehensive 20-item pediatric ERAS protocol, adapted for minimally invasive appendectomy in children aged 5-18 with non-complicated acute appendicitis (ASA I-II), can be implemented with high fidelity and acceptable safety in a tertiary academic pediatric surgery department. We aim to enroll 100 patients to obtain \\~80 evaluable cases. The primary endpoint is the global ERAS compliance rate (target ≥80%, with the lower bound of the 95% confidence interval staying above 70%). Co-primary safety endpoints include Clavien-Dindo ≥III complications and 30-day unplanned readmission rates, both targeted at \\\u003C5%. Secondary endpoints include time to medical readiness for discharge, actual length of stay, opioid sparing, and parent-reported outcomes.\n\nThe study includes a structured run-in phase (first 5 patients) with explicit decision logic to either continue with the protocol unchanged or revise it before full enrollment. Audit-and-feedback cycles every 20 patients monitor compliance drift. The findings will inform a definitive institutional clinical guideline and provide hypothesis-generating data for future multi-center trials.",[27,28,29,30],"Appendectomy, Laparoscopic","Acute Appendicitis","Pediatric Surgery","ERAS","RECRUITING","2026-06-28",{"date":34,"type":35},"2026-07-01","ACTUAL",{"date":37,"type":35},"2026-06-16",{"date":39,"type":21},"2027-08",{"name":41,"class":42},"Ahmet Burak Doğan, MD","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":30,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":65,"locationsCount":43},"100641479","eras-in-total-knee-arthroplasty-a-randomized-controlled-trial-100641479","NCT07655921","ERAS in Total Knee Arthroplasty: a Randomized Controlled Trial","Effectiveness of Enhanced Recovery After Surgery (ERAS) Protocols in Patients Undergoing Total Knee Arthroplasty: A Randomized Controlled Tria","Inclusion Criteria:\n\n* ASA grade of 1-3 BMI was restricted to less than 30 kg\u002Fm²\n\nExclusion Criteria:\n\n* ASA grade of IV or higher uncontrolled comorbidities not consenting to the protocol","50 Years","70 Years",{"count":54,"type":21},120,[24],"Total knee arthroplasty(TKA) is the most commonly performed procedure for advanced knee osteoarthritis. Enhanced recovery after surgery (ERAS) protocols are primarily implemented to reduce perioperative stress and improve surgical and functional outcomes. Evidence of the implementation of ERAS protocols in low to middle-income countries like Pakistan is limited. This study aims to evaluate the effectiveness of ERAS protocols in TKA patients.\n\nA prospective randomized controlled trial study was conducted within our institute from July 2025 to January 2026, in which a total of 239 patients who underwent primary bilateral TKA, of which 121 patients received conventional treatment and protocols, and a study group with 120 participants were managed according to the ERAS protocol. Patients were in the 50-70 years age bracket, and had an American Society of Anesthesiologists grade I-III. The protocol included preoperative physiotherapy, reduced fasting time, multimodal anesthesia, perioperative tranexamic acid, early ambulation and early oral intake. Postoperative outcomes included time to oral intake, postoperative nausea and vomiting, time to mobilization, length of hospital stay, range of motion and Hospital for Special Surgery score.",[30,58],"TKA","2026-06-12",{"date":61,"type":35},"2026-06-18",{"date":63,"type":35},"2025-05-13",{"date":34,"type":21},{"name":66,"class":42},"Liaquat National Hospital & Medical College",{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":77,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":43},"100599231","the-effect-of-perioperative-transcutaneous-electrical-acupoint-stimulation-combined-with-traditional-chinese-medicine-on-gastrointestinal-function-recovery-in-patients-undergoing-abdominal-surgery-100599231","NCT07081802","The Effect of Perioperative Transcutaneous Electrical Acupoint Stimulation Combined With Traditional Chinese Medicine on Gastrointestinal Function Recovery in Patients Undergoing Abdominal Surgery","the Effect of Perioperative Transcutaneous Electrical Acupoint Stimulation Combined With Traditional Chinese Medicine on Gastrointestinal Function Recovery in Abdominal Surgery Patients","Inclusion Criteria:\n\n* Patients aged \\>18 years with no severe preoperative gastrointestinal dysfunction (e.g., no chronic gastrointestinal diseases such as long-term constipation or diarrhea).\n* Scheduled abdominal Grade IV surgeries (limited to liver, gallbladder, pancreas, stomach, or intestinal procedures) performed via open or laparoscopic approach.\n* Preoperative American Society of Anesthesiologists (ASA) Physical Status Classification of I-III.\n* Patients and their families fully understand the study's purpose, methods, potential risks\u002Fbenefits, and provide signed informed consent.\n\nExclusion Criteria:\n\n* Comorbid severe systemic diseases.\n* Local skin abnormalities at acupoints (e.g.,broken skin, infection, allergies, or scarring).\n* Preoperative long-term use (\\>1 month) of gastrointestinal motility-affecting drugs (e.g., mosapride, domperidone) that cannot be discontinued, or allergies to TCM components\u002Felectrode materials.\n* Psychiatric disorders or cognitive impairment rendering patients unable to comply with the study.\n\nElimination Criteria:\n\n* Non-compliance with treatment protocols (e.g., receiving \\\u003C80% of planned sessions).\n* Significant missing data.\n* Occurrence of severe adverse events unrelated to the study intervention.","80 Years",{"count":76,"type":21},148,[24],"Protocol Summary Project Name:Effect of Perioperative TEAS Combined with TCM on Gastrointestinal Function Recovery in Abdominal Surgery Patients Research Objective:To evaluate the impact of perioperative TEAS combined with TCM on postoperative gastrointestinal function, pain, adverse reactions, hospital stay, and complications, as well as its safety, aiming to enrich the ERAS and prehabilitation theory and promote the integration of TCM in surgical practice.\n\nResearch Design:Prospective, randomized, open-label trial involving 148 abdominal surgery patients (Grade IV surgeries) randomly assigned 1:1 to the experimental group (TCM + TEAS + prehabilitation + ERAS) or the control group (prehabilitation + ERAS).\n\nTotal Cases:148 Case Selection\n\nInclusion Criteria:\n\n1. Age 18-80, no severe gastrointestinal dysfunction;\n2. Elective abdominal Grade IV surgeries (pancreas or colorectall surgeries) via open or laparoscopic methods;\n3. Preoperative ASA classification I-III;\n4. Signed informed consent.\n\nExclusion Criteria:\n\nSevere comorbidities, skin abnormalities at acupoints, long-term use of gastrointestinal motility drugs, or other factors affecting the trial.\n\nElimination Criteria:\n\nPoor compliance, significant missing data, or severe adverse events unrelated to the intervention.\n\nTreatment Plan TEAS combined with TCM from the day of surgery to postoperative day 4, alongside prehabilitation and ERAS.\n\nEfficacy Evaluation\n\nPrimary Outcomes:\n\nTime to first flatus and defecation.\n\nSecondary Outcomes:\n\nPostoperative hospital stay, time to tolerate semi-liquid\u002Fsolid food, nausea\u002Fvomiting, pain, bloating, first ambulation, 30-day readmission rate, WBC\u002FCRP levels, and gastrin levels.\n\nSafety Evaluation: Any adverse events. Statistical Methods Continuous variables expressed as mean (SD) or median (IQR); independent t-test for normal distributions. Categorical variables summarized as frequencies\u002Fpercentages, analyzed using χ² or Fisher's exact test. Group differences reported as 95% CI and two-sided P-values (P \\\u003C 0.05 significant). Preset subgroup analyses by surgery type and frailty.",[30,80],"Traditional Chinese Medication (TCM)","2026-05-30",{"date":83,"type":35},"2026-06-02",{"date":85,"type":35},"2025-09-01",{"date":87,"type":21},"2026-09-28",{"name":89,"class":42},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences",{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":96,"eligibilityCriteria":97,"healthyVolunteers":98,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":99,"targetDuration":4,"studyType":22,"phases":101,"briefSummary":102,"conditions":103,"keywords":108,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":43},"100638868","pecha-kucha-based-eras-education-in-cardiovascular-surgery-effects-on-nursing-students-knowledge-and-attitudes-100638868","NCT07606144","Pecha Kucha-Based ERAS Education in Cardiovascular Surgery: Effects on Nursing Students' Knowledge and Attitudes","The Effect of ERAS Education in Cardiovascular Surgery Delivered Using the Pecha Kucha Method on Nursing Students' Knowledge Level and Attitudes Toward Evidence-Based Nursing: A Randomized Controlled Trial","PK-ERAS","Inclusion Criteria:\n\n* Be willing to participate in the study\n* Be a second-year student in the undergraduate Nursing Program at Lokman Hekim University\n* Have access to the Internet\n\nExclusion Criteria:\n\n* Not willing to participate in the study\n\nBe a first-, third-, or fourth-year student in the undergraduate Nursing Program at Lokman Hekim University",true,{"count":100,"type":21},71,[24],"Nursing education is rapidly evolving due to changing healthcare needs and Generation Z learning preferences, which favor short, visual, and interactive methods. Innovative teaching strategies are therefore needed to improve nursing students' critical thinking, clinical decision-making, and problem-solving skills.\n\nThe Pecha Kucha (PK) method is a concise, visual presentation format consisting of 20 slides shown for 20 seconds each. It has been reported to improve attention, learning motivation, and knowledge acquisition in nursing education. However, its use in teaching Enhanced Recovery After Surgery (ERAS) protocols in cardiovascular surgery has not been previously studied.\n\nERAS protocols are evidence-based perioperative care pathways aimed at reducing surgical stress, complications, and recovery time. Nurses play a key role in implementing these protocols, including patient education, pain management, early mobilization, nutrition, and discharge planning. However, nurses' knowledge and application of ERAS remain limited.\n\nThis study aims to evaluate the effect of ERAS education delivered via the Pecha Kucha method on nursing students' knowledge and attitudes toward evidence-based nursing. The study will contribute evidence on innovative teaching strategies in nursing education.\n\nThis experimental study will include 71 second-year nursing students at Lokman Hekim University between May 15, 2026 and May 15, 2027. Data will be analyzed using appropriate parametric or non-parametric tests depending on distribution",[104,105,106,107,30],"Nursing Students","PechaKucha Method","PechaKucha Presentation","Teaching Methods",[109,110,105,111,112,107,30],"nursing","nursing students","PechaKucha","PechaKucha presentation","NOT_YET_RECRUITING","2026-05-22",{"date":116,"type":35},"2026-05-27",{"date":118,"type":21},"2026-05-15",{"date":120,"type":21},"2027-05-15",{"name":122,"class":123},"Lokman Hekim University","OTHER_GOV",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":128,"acronym":129,"eligibilityCriteria":130,"healthyVolunteers":98,"sex":16,"minAge":18,"maxAge":131,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":133,"briefSummary":134,"conditions":135,"keywords":141,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":43},"100614171","the-effect-of-the-cesarean-eras-protocol-on-mother-infant-and-father-infant-bonding-a-multicenter-randomized-controlled-clinical-trial-100614171","NCT07276126","The Effect of the Cesarean ERAS Protocol on Mother-Infant and Father-Infant Bonding: a Multicenter, Randomized Controlled Clinical Trial.","ERAS-CS-BOND-1","IInclusion Criteria:\n\nPregnant women aged 18-60 years.\n\nSingleton, live fetus, and ≥37 weeks of gestation.\n\nUndergoing elective or medically indicated cesarean delivery.\n\nAbility to read and understand Turkish (for questionnaire validity).\n\nMothers and fathers willing and able to complete postpartum follow-up assessments (2 hours, 24 hours, day 4, day 7).\n\nProvision of written informed consent by mother and, if participating, by father\u002Fpartner.\n\nMaternal postpartum clinical stability (no condition precluding questionnaire completion).\n\n❌ Exclusion Criteria (Dışlanma Kriterleri)\n\nExclusion Criteria:\n\nPreterm birth (\\\u003C37 weeks) or multiple gestation (twins, triplets).\n\nStillbirth, early neonatal death, or major congenital anomaly.\n\nNewborn requiring prolonged NICU stay preventing bonding assessments.\n\nMaternal severe obstetric complications:\n\nMassive postpartum hemorrhage\n\nHysterectomy\n\nSevere preeclampsia or eclampsia\n\nSevere postpartum infection\n\nMaternal active psychiatric disorder or use of psychotropic medication.\n\nMaternal need for high-dose opioid analgesia or sedation interfering with bonding assessments.\n\nInability to read\u002Funderstand Turkish or cognitive impairment preventing questionnaire completion.\n\nFailure to complete follow-up visits (2 hours, 24 hours, day 4, day 7).\n\nWithdrawal of consent at any time.","60 Years",{"count":43,"type":21},[24],"This is a multicenter, 1:1 parallel-group, randomized controlled trial designed to compare the effect of the Enhanced Recovery After Cesarean (ERAS) protocol versus standard perioperative care on mother-infant and father-infant bonding in women undergoing cesarean delivery. The study will initially be conducted as a single-center trial at Istanbul Okan University Hospital. Once adequate site preparation is completed, additional centers will be added to expand the study to a multicenter setting.\n\nPrimary Outcome:\n\nThe primary outcome is the total score on the Postpartum Bonding Questionnaire (PBQ) assessed on postpartum day 7, reflecting mother-infant bonding.\n\nSecondary Outcomes:\n\nSecondary outcomes include:\n\nMaternal\u002FParental Postnatal Attachment Scale (MIBS) score at 2 hours postpartum (mother)\n\nPBQ score at 24 hours postpartum (mother)\n\nPBQ score at day 4 postpartum (mother)\n\nPBQ score at day 7 postpartum (father-infant bonding)\n\nEdinburgh Postnatal Depression Scale (EPDS) scores for mothers at 2 hours and 7 days postpartum\n\nTime to initiation of breastfeeding\n\nRequirement for neonatal intensive care unit (NICU) admission\n\nSample Size:\n\nThe total multicenter target sample size is n=300, with 150 participants in the ERAS group and 150 in the standard care group. The initial single-center phase at Okan University Hospital will enroll a target of n=100 participants (50 per group).\n\nRandomization:\n\nParticipants will be randomized using a block and stratified randomization approach based on parity (primiparous vs multiparous) and planned type of anesthesia.\n\nBlinding (Masking):\n\nDue to the nature of the intervention, care providers cannot be blinded to group assignment. However, outcome assessors and data analysts will remain blinded to treatment allocation to minimize bias.\n\nStudy Timeline and Visits:\n\nParticipants will be evaluated at multiple time points following cesarean delivery: 2 hours postpartum, 24 hours postpartum, day 4 postpartum, and day 7 postpartum. All primary and secondary outcomes will be collected at the specified time points.\n\nSignificance and Rationale:\n\nThe ERAS protocol for cesarean delivery is designed to optimize perioperative care, enhance recovery, and potentially improve early parent-infant bonding. While previous studies have focused on maternal recovery and clinical outcomes, evidence regarding the impact of ERAS on both mother-infant and father-infant bonding remains limited. This trial aims to provide high-quality evidence on whether ERAS implementation can improve early bonding experiences, maternal mental health, breastfeeding initiation, and neonatal outcomes compared with standard perioperative care. The findings may guide future clinical practice and contribute to optimizing family-centered care in cesarean deliveries.\n\nKey Features:\n\nMulticenter, randomized controlled design\n\nParallel 1:1 allocation\n\nStratified randomization by parity and anesthesia type\n\nBlinded outcome assessment and data analysis\n\nMultiple postpartum evaluation points\n\nFocus on psychosocial and clinical outcomes\n\nExpected Contributions:\n\nThis study will provide comprehensive data on the feasibility and effectiveness of ERAS protocols in cesarean deliveries and their potential benefits for both maternal and paternal bonding with the newborn. The inclusion of both mother-infant and father-infant outcomes, as well as maternal mental health and breastfeeding indicators, ensures a holistic assessment of early family-centered outcomes.",[136,30,137,138,139,140],"Bonding","Cesarean Section","Maternal Care","Father - Child Relations","Mother-Infant Interaction",[142,143,144,145,146],"eras","erac","cesarean","maternal bonding","paternal bonding","2026-04-27",{"date":149,"type":35},"2026-04-28",{"date":151,"type":35},"2025-12-13",{"date":153,"type":21},"2026-04-20",{"name":155,"class":42},"Okan University",{"id":157,"slug":158,"hasResults":11,"nctId":159,"briefTitle":160,"officialTitle":161,"acronym":4,"eligibilityCriteria":162,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":22,"phases":166,"briefSummary":167,"conditions":168,"keywords":4,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":4},"100628336","comparison-of-anesthetic-techniques-for-early-recovery-after-ankle-arthroscopy-100628336","NCT07460310","Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy","Comparison of Total Intravenous, Balanced, and Spinal Anesthesia for Early Recovery Following Ankle Arthroscopy: A Multicenter, Prospective, Randomized Controlled Trial.","Inclusion Criteria:\n\n* Full understanding of the study procedures and methods, with a signed written informed consent form.\n* Aged 18 to 65 years, of either sex.\n* Scheduled for elective unilateral minimally invasive ankle surgery.\n* American Society of Anesthesiologists (ASA) physical status classification I or II.\n* Body Mass Index (BMI) between 16 and 32 kg\u002Fm\\^2\n\nExclusion Criteria:\n\n* Known hypersensitivity or allergy to any study medications or existing contraindications to anesthesia.\n* Chronic obstructive pulmonary disease (COPD) or unstable asthma.\n* History of difficult airway management, poorly controlled gastroesophageal reflux disease (GERD), or a known risk of aspiration.\n* Anticipated surgical duration exceeding 3 hours.\n* History of chronic preoperative opioid use or dependence.\n* History of severe postoperative adverse reactions (e.g., severe postoperative nausea and vomiting).\n* Pregnancy or lactation.\n* History of seizure disorders or epilepsy.\n* Severe peripheral neuropathy.\n* Any other condition that, in the opinion of the investigator, would preclude safe participation in the study.","65 Years",{"count":165,"type":21},200,[24],"Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence comparing anesthetic strategies in ankle arthroscopy is limited.\n\nThis multicenter randomized trial compares total intravenous anesthesia with propofol plus peripheral nerve block (PNB), general anesthesia plus PNB, and spinal anesthesia, with PACU-I recovery time as the primary outcome. Secondary outcomes include postoperative pain, opioid consumption, hospital length of stay, adverse events, recovery quality, satisfaction, limb weakness, and intraoperative hemodynamics.",[169,170,171,30,172],"Ankle Sprain","Ankle (Ligaments); Instability (Old Injury)","Pain Management","Ankle Arthroscopy","2026-03-04",{"date":175,"type":35},"2026-03-10",{"date":177,"type":21},"2026-03-01",{"date":179,"type":21},"2026-12-30",{"name":181,"class":42},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":187,"acronym":4,"eligibilityCriteria":188,"healthyVolunteers":11,"sex":189,"minAge":190,"maxAge":131,"enrollmentInfo":191,"targetDuration":4,"studyType":22,"phases":193,"briefSummary":195,"conditions":196,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":197,"lastUpdatePostDateStruct":198,"startDateStruct":200,"completionDateStruct":202,"leadSponsor":204,"locationsCount":43},"100601904","phase-4-impact-of-eras-protocol-on-length-of-hospital-stay-after-laparoscopic-surgeries-100601904","NCT07116564","Impact of ERAS Protocol on Length of Hospital Stay After Laparoscopic Surgeries","Impact of Multimodal Analgesia and ERAS Protocol on Length of Hospital Stay After Laparoscopic Gynecological Surgeries: A Randomized Control Trial","Inclusion Criteria:\n\n* ASA physical status I, II, and III\n* Patients scheduled for elective laparoscopic gynecological surgeries\n\nExclusion Criteria:\n\n* Refusal to participate\n* History of allergy or contraindication to study drugs\n* Patients in which procedure converted to open surgery\n* Diagnostic laparoscopic procedures\n* Patients with a history of severe anxiety or depression","FEMALE","20 Years",{"count":192,"type":21},98,[194],"PHASE4","The goal of this clinical trial is to determine the length of hospital stay in patients using multimodal analgesia with or without ERAS protocol scheduled for elective laparoscopic gynecological surgeries",[30],"2026-02-12",{"date":199,"type":35},"2026-02-17",{"date":201,"type":35},"2025-08-20",{"date":203,"type":21},"2026-11-01",{"name":205,"class":42},"Aga Khan University",{"id":207,"slug":208,"hasResults":11,"nctId":209,"briefTitle":210,"officialTitle":210,"acronym":30,"eligibilityCriteria":211,"healthyVolunteers":11,"sex":189,"minAge":18,"maxAge":212,"enrollmentInfo":213,"targetDuration":4,"studyType":214,"phases":4,"briefSummary":215,"conditions":216,"keywords":218,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":223,"completionDateStruct":225,"leadSponsor":227,"locationsCount":4},"100611618","enhanced-recovery-after-emergency-cesarean-section-a-comparative-study-assessing-postoperative-recovery-and-outcomes-100611618","NCT07242924","Enhanced Recovery After Emergency Cesarean Section: A Comparative Study Assessing Postoperative Recovery and Outcomes","Inclusion Criteria:\n\n* singleton pregnancy who undergoing emergency cesarean section after 34weeks and accepting to be included in the study.\n\nExclusion Criteria:\n\n* Pregnant woman who had previous rupture uterus.\n* Other medical disorders as hypertensive disorder during pregnancy, cardiac disease.\n* Intra-operative complications necessitating changes in post-operative care e.g. bowel injury, urinary tract injury.\n* Hemodynamically unstable (post-partum hemorrhage)","45 Years",{"count":20,"type":21},"OBSERVATIONAL","Cesarean section (CS) remains one of the most common major surgical procedures worldwide, with emergency CS accounting for approximately 30% of cases. Emergency CS presents unique challenges including increased maternal stress, higher complication rates, and prolonged recovery compared to elective procedures . Enhanced Recovery After Surgery (ERAS) protocols offer a promising approach to optimize outcomes in this population.\n\nOriginally developed for colorectal surgery, ERAS principles have been successfully adapted to obstetric practice over the past decade. These evidence-based protocols emphasize multimodal interventions including preoperative counseling, optimized analgesia, early mobilization, and timely nutrition. In obstetrics, ERAS implementation has demonstrated reduced length of stay, decreased opioid use, and improved patient satisfaction for elective CS .\n\nApplication of ERAS to emergency CS requires special considerations due to the urgent nature of the procedure. Modified protocols focus on rapid preoperative assessment, regional anesthesia with intrathecal opioids, and immediate postoperative care initiation . Emerging evidence suggests these adaptations maintain benefits while accommodating time constraints . Key outcomes include reduced postoperative pain, earlier return of bowel function, and improved breastfeeding rates .\n\nCurrent research demonstrates ERAS protocols can be safely implemented in emergency CS with proper staff training and institutional support . Ongoing studies continue to refine optimal practices, particularly regarding fluid management and thromboprophylaxis . As evidence accumulates, standardized guidelines for emergency CS ERAS pathways are expected to emerge .",[30,217],"Cesarean Section Pain",[30,219],"ERAS, emergency cs","2025-11-19",{"date":222,"type":35},"2025-11-21",{"date":224,"type":21},"2025-12-01",{"date":226,"type":21},"2028-12-01",{"name":228,"class":42},"Assiut University",{"id":230,"slug":231,"hasResults":11,"nctId":232,"briefTitle":233,"officialTitle":234,"acronym":235,"eligibilityCriteria":236,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":237,"targetDuration":4,"studyType":22,"phases":239,"briefSummary":240,"conditions":241,"keywords":245,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":248,"lastUpdatePostDateStruct":249,"startDateStruct":251,"completionDateStruct":253,"leadSponsor":255,"locationsCount":257},"100576555","impact-of-a-technology-platform-based-on-enhanced-recovery-aftereras-surgery-on-length-of-stay-after-coronary-artery-bypass-grafting-timely-project-100576555","NCT06786819","Impact of a Technology Platform Based on Enhanced Recovery After(ERAS) Surgery on Length of Stay After Coronary Artery Bypass Grafting: Timely Project","Estudo Randomizado de Cluster Escalonado Para Avaliar o Impacto de Uma Plataforma tecnológica Baseada no ERAS (Enhanced Recovery After Surgery) no Tempo de permanência após Cirurgia de revascularização miocárdica: Projeto Tempos Certos - REPLICCAR III","REPLICCARIII","Inclusion Criteria:\n\n* Adults over 18 years old\n* Indication for primary isolated CABG (elective or urgent status)\n* Own a personal cell phone\n* Have internet access\n* Knowledgeable in using the device\n* Full understanding and agreement regarding the informed consent form (ICF)\n\nExclusion Criteria:\n\n* Indication for associated surgery\n* Glycosylated hemoglobin level greater than 8%\n* Creatinine clearance less than 30 mL\u002Fmin\n* Pre-operative atrial fibrillation or use of pre-operative anticoagulation\n* Hemoglobin less than 12 g\u002FdL\n* Users of illicit drugs\n* STS score greater than 4%\n* Physical or mental disabilities that prevent adherence to the protocol\n* Refusal by the patient or family member",{"count":238,"type":21},480,[24],"Cardiovascular diseases continue to be the leading cause of death worldwide. Among them, coronary artery disease has the greatest impact, being characterized as one of the main causes of death in Brazil over the last decade. One of the well-established treatments is coronary artery bypass grafting, which is the most performed among cardiac surgeries and, in our scenario, is primarily funded by the Unified Health System (SUS). The information obtained from the Paulista Registry of Cardiovascular Surgeries (REPLICCAR), in partnership with FAPESP, has been important for implementing improvements in the landscape of cardiac surgeries in the state of São Paulo. Although outcomes in cardiac surgery have improved due to the structuring and organization of quality programs, this is still not a reality at the national level. In a situation where data collection and quality initiatives play a central role in continuous improvement, generating value becomes essential for the sustainability of cardiac surgery programs. In this sense, the concept of Enhanced Recovery After Surgery (ERAS) has gained increasing traction. This concept is based on multidisciplinary protocols and scientific evidence, which help prepare patients for rapid recovery, resulting in reduced complications, shorter hospital stays, and, primarily, lower hospital costs. On the other hand, the increase in surgical waiting lists has also led to a rise in home mortality due to cardiac causes. Thus, among the various challenges imposed by the current scenario, the investigators believe that preparing patients for rapid recovery after coronary artery bypass grafting presents an opportunity for the sustainability of the healthcare system. Therefore, the aim of this project is to evaluate the impact of a technology platform based on ERAS on the postoperative recovery time of patients undergoing coronary artery bypass grafting in reference centers in the state of São Paulo, Timely Project - REPLICCAR III.",[30,242,243,244],"Cardiac Surgery","Cardiac Surgery-CABG","Digital Health",[242,246,247,30,244],"CABG","ERASCS","2025-10-02",{"date":250,"type":35},"2025-10-03",{"date":252,"type":35},"2025-03-10",{"date":254,"type":21},"2026-09-01",{"name":256,"class":42},"University of Sao Paulo General Hospital",2,{"id":259,"slug":260,"hasResults":11,"nctId":261,"briefTitle":262,"officialTitle":263,"acronym":4,"eligibilityCriteria":264,"healthyVolunteers":11,"sex":16,"minAge":265,"maxAge":266,"enrollmentInfo":267,"targetDuration":4,"studyType":22,"phases":269,"briefSummary":270,"conditions":271,"keywords":274,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":280,"lastUpdatePostDateStruct":281,"startDateStruct":282,"completionDateStruct":284,"leadSponsor":286,"locationsCount":43},"100608844","pediatric-colostomy-reversal-traditional-care-vs-enhanced-recovery-after-surgery-100608844","NCT07206836","Pediatric Colostomy Reversal: Traditional Care vs. Enhanced Recovery After Surgery","Comparison of Outcome of Colostomy Reversal in Pediatric Patients With Enhanced Recovery After Surgery Versus Traditional Care Protocols.","Inclusion Criteria:\n\n* Patients with Colostomy\n* Admitted for Reversal of colostomy\n\nExclusion Criteria:\n\n* Patients with endocrinal abnormalities\n* Patients with cardiac abnormalities\n* Patients with spinal abnormalities\n* Patients with bleeding abnormalities\n* Patients who have undergone previous multiple abdominal surgeries","2 Years","13 Years",{"count":268,"type":21},60,[24],"The goal of this clinical trial is to learn whether using an Enhanced Recovery After Surgery (ERAS) protocol helps children recover faster after colostomy reversal compared with traditional care.\n\nThe main question it aims to answer is:\n\nDoes ERAS lower the number of days children need to stay in the hospital after colostomy reversal compared with traditional care?\n\nResearchers will compare two groups:\n\nERAS group - Children receive shorter pre-surgery fasting, no mechanical bowel preparation, early pain control, and early feeding after surgery.\n\nTraditional care group - Children receive the usual long bowel preparation, overnight fasting, opioid pain medicine, and a longer period without food after surgery.\n\nParticipants will:\n\nBe randomly assigned to either the ERAS or traditional care group\n\nHave their colostomy surgically closed by experienced pediatric surgeons\n\nBe monitored daily until they can eat a solid meal without vomiting; this marks the end of their hospital stay\n\nThe study will enroll 60 children ages 2-13 at Children's Hospital Faisalabad, Pakistan.\n\nResearchers will measure length of hospital stay from surgery until discharge as the main outcome.",[272,273,30],"Colostomy - Stoma","Stoma Reversal Procedure",[275,276,277,30,278,279],"Pediatric Colostomy","Colostomy Reversal","Enhanced Recovery After Surgery","Traditional Care protocol","Length of Hospital Stay","2025-10-01",{"date":250,"type":35},{"date":283,"type":35},"2025-08-01",{"date":285,"type":21},"2025-11",{"name":287,"class":42},"Children Hospital Faisalabad",{"id":289,"slug":290,"hasResults":11,"nctId":291,"briefTitle":292,"officialTitle":293,"acronym":294,"eligibilityCriteria":295,"healthyVolunteers":11,"sex":189,"minAge":18,"maxAge":296,"enrollmentInfo":297,"targetDuration":4,"studyType":22,"phases":298,"briefSummary":299,"conditions":300,"keywords":311,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":314,"lastUpdatePostDateStruct":315,"startDateStruct":317,"completionDateStruct":318,"leadSponsor":320,"locationsCount":43},"100609100","pre-habilitation-within-eras-protocol-for-gynecologic-oncology-surgery-the-preeras-study-100609100","NCT07210164","Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study","Prehabilitation With Exercise and Immunonutrition (Ocoxin®) in the Perioperative Management of Gynecologic Malignancies Under ERAS Protocol.","Pre_ERAS","Inclusion Criteria:\n\n* Type of gynecological malignancy: endometrial cancer, ovarian cancer, cervical cancer, treated with laparotomy after the decision of the gynecological-oncology unit (positive opinion of the Multidisciplinary Tumor Board - MDT)\n* Patient age: 18 to 85 years\n* General condition of the patient: ASA score I-III\n* Consent to implement the accelerated recovery protocol - Enhanced recovery after surgery (ERAS)\n* Sufficient understanding of the Greek language\n* Provision of signed, after thorough information, consent to participate in the study\n\nExclusion Criteria:\n\n* Women with performance status: ECOG \\>2 and ASA score \\>III\n* Women who have not been informed and have given written consent","85 Years",{"count":20,"type":21},[24],"ERAS (Enhanced Recovery After Surgery) protocols are step-by-step care plans that help patients recover faster after surgery. They focus on keeping the body's normal functions, lowering stress from surgery, and supporting a quicker recovery. In gynecologic cancer surgeries, ERAS has been shown to help patients do better, have fewer problems, and leave the hospital sooner.\n\nA prehabilitation program, in combination with ERAS protocols, aims to optimize patients' physical and psychological condition prior to surgery for gynecological cancers. Interventions may include tailored exercise, nutritional support, respiratory training, and psychological preparation. By enhancing baseline fitness and resilience, prehabilitation improves the body's ability to tolerate surgical stress, reduces complications, and facilitates a faster, smoother recovery within the ERAS framework.",[30,301,302,303,304,305,306,307,308,309,310],"Compliance","Quality of Life (QOL)","Excercise","Immunonutrition","Post Operative Pain","Laparotomy Patients","Surgical Complication","Gynaecological Malignancies","Gynaecologic Cancer","Gynaecological Oncology",[312,30,313,304],"Prehabilitation","Gynecologic Cancers","2025-09-29",{"date":316,"type":35},"2025-10-07",{"date":224,"type":21},{"date":319,"type":21},"2029-12-30",{"name":321,"class":42},"Aristotle University Of Thessaloniki",{"id":323,"slug":324,"hasResults":11,"nctId":325,"briefTitle":326,"officialTitle":327,"acronym":4,"eligibilityCriteria":328,"healthyVolunteers":11,"sex":189,"minAge":18,"maxAge":52,"enrollmentInfo":329,"targetDuration":4,"studyType":22,"phases":331,"briefSummary":332,"conditions":333,"keywords":335,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":337,"lastUpdatePostDateStruct":338,"startDateStruct":340,"completionDateStruct":342,"leadSponsor":344,"locationsCount":43},"100599659","enhanced-recovery-after-surgeryeras-following-gynaecological-oncology-surgery-in-a-tertiary-level-hospital-100599659","NCT07087366","Enhanced Recovery After Surgery(ERAS) Following Gynaecological Oncology Surgery in a Tertiary Level Hospital","Enhanced Recovery After Surgery(ERAS) Pathway Following Gynecological Oncology Surgery in a Tertiary Level Hospital:A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients between the age of 18-70 years,\n* diagnosed case with cervical, uterine or ovarian cancer,\n* Admitted for surgical management .\n\nExclusion Criteria:\n\n* Patients with severe comorbidity, including DM,CRD,CLD\n* patients with American Society of Anesthesiologists risk ≥ 4,\n* severe organ dysfunction or failure.",{"count":330,"type":21},130,[24],"Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery after surgical procedures by maintaining preoperative organ function and reducing the profound stress response following surgery.\n\nThe principle of ERAS is to optimize the patient's health before surgery, minimize stress to the body, and restore function to normal rapidly by taking steps before, during, and after surgery, to decrease the length of stay in the hospital, reduce recovery time, prevent complications, readmissions, same day discharge (SDD) and patient's satisfaction.\n\nThe aim of this study is to introduce the ERAS recommendations into the management of gynaecological surgical procedures in compared to conventional procedures.\n\nAfter taking permission from Institutional Review Board (IRB) of BSMMU, the proposed study will be started. After taking informed written consent and matching eligibility criteria, a total 160 patients will be selected in this prospective randomized control study. This study will be conducted in the Department of gynecological oncology, BSMMU for two years from April 2024 to March 2026. There will be two group in this study, patients of Group A will be selected for ERAS protocol from preoperative to postoperative event up to follow up. Patients of Group B will be selected for conventional method. Outcome of both procedure in terms of hospital stay, costs, requirement of analgesia and complications will be compared. Statistical analyses of the results will be obtained by using window-based computer software devised with Statistical Packages for Social Sciences (SPSS-25).",[30,334],"Cancer",[336],"RCT","2025-08-02",{"date":339,"type":35},"2025-08-07",{"date":341,"type":35},"2025-06-01",{"date":343,"type":21},"2027-06-30",{"name":345,"class":42},"Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh",{"id":347,"slug":348,"hasResults":11,"nctId":349,"briefTitle":350,"officialTitle":350,"acronym":4,"eligibilityCriteria":351,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":352,"targetDuration":4,"studyType":22,"phases":353,"briefSummary":354,"conditions":355,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":358,"lastUpdatePostDateStruct":359,"startDateStruct":361,"completionDateStruct":363,"leadSponsor":365,"locationsCount":43},"100596612","comparative-outcome-of-early-and-standard-oral-feeding-after-emergency-bowel-surgery-100596612","NCT07047729","COMPARATIVE OUTCOME OF EARLY AND STANDARD ORAL FEEDING AFTER EMERGENCY BOWEL SURGERY","Inclusion Criteria:\n\n* Either Gender\n* Requiring emergency surgery due to conditions such as obstructive bowel disease, GI perforation, colorectal surgery, blunt abdominal trauma (resulting from falls or roadside accidents), and penetrating abdominal trauma (involving firearm injuries and stab wounds).\n\nExclusion Criteria:\n\n* Patients with terminal cancer need palliative surgery (as their focus is on comfort care rather than surgical intervention).\n* Patients who had undergone surgery within the past 30 days (to avoid potential complications associated with recent surgical procedures).\n* Patients receive regular renal replacement therapy (to prevent additional stress on their medical condition).\n* Pregnant women (as surgical interventions may pose risks to both the mother and the unborn child).",{"count":268,"type":21},[24],"Informed consent will be obtained from patients or their legal representatives in cases where the patient is unconscious. Patient information, including names, ages, gender, smoking history, comorbidities, and the indication for emergency surgical procedures, will be documented. All surgical procedures will follow standard protocols and will be conducted by a single surgical team led by at least two consultants, each with more than five years of experience. All 60 patients will be randomly allocated into two groups using a random number table: Group A (early oral feeding), consisting of 30 patients, and Group B (standard oral feeding), consisting of 30 patients. In Group A, a liquid diet will be initiated within 24 hours after surgery and, if well-tolerated without vomiting, will transition to a regular diet over the subsequent 24 hours. On the other hand, in Group B, a standard diet (late feeding), including liquid filtrates, will only be introduced after the resolution of the ileus, during which these patients will remain NPO (nothing by mouth).",[356,357,30],"Bowel Surgery","Emergency Abdominal Surgery","2025-06-24",{"date":360,"type":35},"2025-07-02",{"date":362,"type":35},"2025-03-06",{"date":364,"type":21},"2025-09-06",{"name":366,"class":42},"Dr Hamail Khanum",{"id":368,"slug":369,"hasResults":11,"nctId":370,"briefTitle":371,"officialTitle":372,"acronym":4,"eligibilityCriteria":373,"healthyVolunteers":11,"sex":16,"minAge":374,"maxAge":4,"enrollmentInfo":375,"targetDuration":4,"studyType":22,"phases":377,"briefSummary":378,"conditions":379,"keywords":382,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":383,"lastUpdatePostDateStruct":384,"startDateStruct":386,"completionDateStruct":388,"leadSponsor":390,"locationsCount":43},"100594278","eras-program-implementation-for-mipd-100594278","NCT07017361","ERAS Program Implementation for MIPD","A Multicenter Randomized Prospective Study on Establishing an ERAS Program and Optimized Clinical Protocol for Patients Undergoing Minimally Invasive Pancreatoduodenectomy (MIPD)","Inclusion Criteria:\n\n* Age ≥ 19 years, scheduled for standard minimally invasive (robotic or laparoscopic) pancreatoduodenectomy for periampullary tumors\n* ECOG performance status of 0 or 1 at screening\n* Able to provide written informed consent, understand study procedures, and complete patient-reported questionnaires\n* ASA physical status classification I-III\n\nExclusion Criteria:\n\n* Hypersensitivity to fentanyl or ropivacaine\n* Cognitive impairment preventing independent use of patient-controlled analgesia or completion of questionnaires\n* Major internal medical or psychiatric disorders affecting treatment response\n* Severe hepatic or renal dysfunction\n* Any condition deemed inappropriate for study participation by the investigator","19 Years",{"count":376,"type":21},140,[24],"To evaluate the impact of an Enhanced Recovery After Surgery (ERAS) program on postoperative recovery in patients undergoing minimally invasive pancreatoduodenectomy (MIPD)",[380,30,381],"Pancreaticoduodenectomy","Minimally Invasive Surgery",[380,30,381],"2025-06-14",{"date":385,"type":35},"2025-06-17",{"date":387,"type":21},"2025-07-15",{"date":389,"type":21},"2027-12-31",{"name":391,"class":42},"Seoul National University Hospital",{"id":393,"slug":394,"hasResults":11,"nctId":395,"briefTitle":396,"officialTitle":397,"acronym":4,"eligibilityCriteria":398,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":4,"enrollmentInfo":399,"targetDuration":400,"studyType":214,"phases":4,"briefSummary":401,"conditions":402,"keywords":409,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":415,"startDateStruct":417,"completionDateStruct":419,"leadSponsor":421,"locationsCount":43},"100479104","compliance-with-eras-protocol-in-pancreatic-surgery-stress-response-and-outcomes-100479104","NCT05518643","Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes","Enhanced Recovery Program, Patient Reported Outcomes, Surgery-specific Outcomes and Stress Response After Pancreatic Surgery: A Prospective Observational Cohort Study by the Thessalic Pancreas Study Group (ThePANas).","Inclusion Criteria:\n\n* all pancreatic surgery patients\n* above the age of 18\n* fluent greek speakers\n* without communication barriers\n\nExclusion Criteria:\n\n* younger than 18 years-old\n* unable or unwilling to participate\n* other surgical procedures\n* communication barriers\n* lost to follow-up",{"count":54,"type":21},"1 Year","The purpose of this study is to evaluate the impact of compliance with enhanced recovery after surgery (ERAS) program on patient reported outcomes (PROs), surgery-specific outcomes and stress response after pancreatic surgery.\n\nThis prospective observational study will include all consecutive patients undergoing pancreatic surgery over a period of three years (2022 - 2025) at two sites, namely University General Hospital of Larissa and IASO Thessalias, in Greece. Patients will be prospectively enrolled after written informed consent. Data will be collected on patient characteristics, surgical and anaesthetic techniques, complications, and length of stay. Quality of life questionnaires will be administered to patients preoperatively, on the fith postoperative day, first follow-up after discharge, one month and six months after the operation. The stress response will be assessed by measuring the Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio (NLR and PLR) preoperatively, and on the first five postoperative days. Data will be collected on pancreatic surgery-specific complications such as delayed gastric emptying (DGE), post-pancreatectomy haemorrhage (PPH) and postoperative pancreatic fistula (POPF) formation. Anonymised data will be uploaded by the principal investigator on a protected excel spreadsheet for analysis.",[30,403,404,405,406,407,408],"Pancreas Cancer","Pancreas; Fistula","Delayed Gastric Emptying","Surgery-Complications","Pancreatic Hemorrhage","PROMs",[30,403,408,410,406,411,412,413],"Stress response to surgery","PLR","NLR","Quality of Life","2025-04-16",{"date":416,"type":35},"2025-04-22",{"date":418,"type":35},"2022-07-15",{"date":420,"type":21},"2025-06",{"name":422,"class":42},"University of Thessaly",{"id":424,"slug":425,"hasResults":11,"nctId":426,"briefTitle":427,"officialTitle":428,"acronym":4,"eligibilityCriteria":429,"healthyVolunteers":11,"sex":189,"minAge":190,"maxAge":74,"enrollmentInfo":430,"targetDuration":4,"studyType":214,"phases":4,"briefSummary":431,"conditions":432,"keywords":4,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":434,"startDateStruct":436,"completionDateStruct":438,"leadSponsor":440,"locationsCount":4},"100583573","eras-and-postoperative-recovery-in-gynecologic-patients-a-qor-15-study-100583573","NCT06878079","ERAS and Postoperative Recovery in Gynecologic Patients: A QoR-15 Study","Assessing Enhanced Recovery After Surgery (ERAS) Intervention Impact on Postoperative Recovery in Gynecological Patients Using QoR-15 Questionnaire","Inclusion Criteria:\n\n* Age between 20 and 80 years.\n* Undergoing routine gynecological surgery, including total or subtotal hysterectomy, myomectomy, oophorectomy, gynecologic cancer staging surgery, cytoreductive surgery, and pelvic exenteration.\n* Cancer patients with an Eastern Cooperative Oncology Group (ECOG) performance status of ≤2.\n* Receiving either standard perioperative care or ERAS protocol-based care.\n\nExclusion Criteria:\n\n* Age below 20 years.\n* Lack of decision-making capacity.\n* Undergoing emergency surgery.\n* History of clinical depression.\n* Undergoing palliative surgery.\n* History of chronic pain.",{"count":330,"type":21},"The Quality of Recovery-15 (QoR-15) questionnaire is a widely used Patient-Reported Outcome Measure (PROM) for evaluating postoperative recovery, including pain, physical function, and emotional well-being. Enhanced Recovery After Surgery (ERAS) is a multidisciplinary care model designed to optimize perioperative management through standardized protocols.\n\nFor gynecological surgery, ERAS emphasizes preoperative education, early interventions (e.g., smoking cessation, anemia management, nutrition optimization), intraoperative strategies (e.g., fluid balance, nausea prevention, temperature control), and postoperative care (e.g., early mobilization, pain control, ileus prevention). However, while ERAS is gaining acceptance, its effectiveness can vary due to workload, patient variability, and institutional resources, and its superiority over traditional care remains inconclusive.\n\nThis study aims to objectively compare ERAS and traditional perioperative care using the QoR-15 questionnaire to assess patient satisfaction, recovery speed, surgical risk reduction, and complication prevention. Rather than solely promoting ERAS, this research seeks to evaluate its applicability, enhance personalized care, and provide scientific evidence for perioperative management optimization.",[433,30],"Gynecologic",{"date":435,"type":35},"2025-03-14",{"date":437,"type":21},"2025-03",{"date":439,"type":21},"2026-06",{"name":441,"class":42},"National Taiwan University Hospital",{"id":443,"slug":444,"hasResults":11,"nctId":445,"briefTitle":446,"officialTitle":447,"acronym":448,"eligibilityCriteria":449,"healthyVolunteers":11,"sex":189,"minAge":450,"maxAge":296,"enrollmentInfo":451,"targetDuration":453,"studyType":214,"phases":4,"briefSummary":454,"conditions":455,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":460,"lastUpdatePostDateStruct":461,"startDateStruct":463,"completionDateStruct":465,"leadSponsor":467,"locationsCount":469},"100566463","enhanced-recovery-protocols-in-gynecologic-oncology-100566463","NCT06655506","Enhanced Recovery Protocols in Gynecologic Oncology","Enhanced Recovery Protocols in Gynecological Cancer Patients: a Feasibility Study","ERGO","Inclusion Criteria:\n\npatients with gynaecological cancer and an ECOG performance status \\\u003C4, ASA score \\\u003C4.\n\nExclusion Criteria:\n\npatients with metastatic cancer of non-gynaecological origin patients that are not able to follow ERAS protocol due to medical reasons patients with severe debilitating comorbidities (ECOG status 4, ASA score 4-5)","25 Years",{"count":452,"type":21},600,"60 Days","Enhanced Recovery After Surgery (ERAS) are developed to provide a systematic structure for managing postsurgical patients.These protocols promote evidenced-based practices and implement a multidisciplinary effort to maintain normal physiology in the perioperative period and aid in earlier recovery. The present study aims to investigate the feasibility of and compliance to a structured ERAS protocol among Gynecological Oncological Centers in Greece as well as to compare the outcomes among patients that fullfilled the minimum number of necessary criteria, compared to those that were enrolled in ERAS protocols but did not meet the sufficient necessary criteria.",[30,456,457,458,413,459],"Gynecologic Cancer","Perioperative Complication","Postoperative Pain","Infections","2024-10-22",{"date":462,"type":35},"2024-10-23",{"date":464,"type":35},"2024-10-20",{"date":466,"type":21},"2026-07-30",{"name":468,"class":42},"National and Kapodistrian University of Athens",8,{"id":471,"slug":472,"hasResults":11,"nctId":473,"briefTitle":474,"officialTitle":475,"acronym":4,"eligibilityCriteria":476,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":296,"enrollmentInfo":477,"targetDuration":4,"studyType":22,"phases":479,"briefSummary":480,"conditions":481,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":484,"lastUpdatePostDateStruct":485,"startDateStruct":487,"completionDateStruct":489,"leadSponsor":490,"locationsCount":43},"100397157","lung-surgery-with-enhanced-recovery-vs-lung-surgery-without-enhanced-recovery-100397157","NCT04451473","Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery","The Short Term and Long Term Comparison of Lung Surgery With or Without Enhanced Recovery","Inclusion Criteria: patients with stage I-IIIa Non-small-cell Lung Cancer underwent radical resection or other benign lung lesions need VATS surgery.\n\n\\-\n\nExclusion Criteria: cardio-pulmonary function couldn't tolerate surgery\n\n\\-",{"count":478,"type":21},350,[24],"Objective: The adoption of Enhanced Recovery Surgery programs in lung resection is relatively recent with limited outcome data. This study aimed to determine the impact of an Enhanced Recovery Surgery pathway on short- term and long- term results in patients undergoing lung resection for primary lung cancer.\n\nMethods: A Randomized Controlled Trial was designed to collect the perioperative data on consecutive patients undergoing lung resection for primary lung cancer. Patients will be randomizely assigned to the ERAS- Group and Control- Group. Short-term and long- term effect will be compared between the two groups.",[482,483,30],"Lung Cancer","Surgery","2022-11-14",{"date":486,"type":35},"2022-11-16",{"date":488,"type":35},"2019-10-08",{"date":343,"type":21},{"name":491,"class":42},"The Second Hospital of Shandong University"]