[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"erector-spina-plan-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:erector-spina-plan-block":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,77,100],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100620859","single--versus-two-level-esp-block-for-analgesia-after-lumbar-stabilization-surgery-100620859",false,"NCT07363096","Single- Versus Two-Level ESP Block for Analgesia After Lumbar Stabilization Surgery","Comparison Of Single- Versus Two-Level Erector Spinae Plane Block For Postoperative Analgesia In Patients Undergoing Lumbar Stabilization Surgery","ESP-Lumbar","Inclusion Criteria:\n\n* ASA I-II-III,\n* BMI:18-40,\n* Patients undergoing lumbar stabilization surgery involving 2 to 4 vertebral levels\n* Patients who personally provide written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Patients with chronic pain conditions\n* Patients with a history of chronic opioid use\n* Patients undergoing emergency lumbar stabilization surgery","ALL","18 Years","80 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","Lumbar stabilization surgery is commonly associated with moderate to severe postoperative pain. Effective pain control is important to improve patient comfort, early mobilization, and recovery. The erector spinae plane (ESP) block is a regional anesthesia technique that has been increasingly used for postoperative pain management in spine surgery.\n\nThis study aims to compare the effectiveness of single-level versus two-level ultrasound-guided ESP block for postoperative pain control in patients undergoing lumbar stabilization surgery. Patients will be randomly assigned to receive either a single-level ESP block or a two-level ESP block in addition to standard analgesic treatment.\n\nPostoperative pain scores, opioid consumption, and the incidence of side effects will be evaluated during the postoperative period. The results of this study may help determine the most effective ESP block technique for pain management after lumbar stabilization surgery.",[28,29,30],"Postoperative Pain Management","Lumbar Spinal Fusion Surgery","Erector Spina Plan Block",[32,33,28],"Erector Spina Plane Block","Acute Pain","NOT_YET_RECRUITING","2026-01-15",{"date":37,"type":38},"2026-01-23","ACTUAL",{"date":40,"type":22},"2026-02-01",{"date":42,"type":22},"2027-01-03",{"name":44,"class":45},"Ankara Etlik City Hospital","OTHER_GOV",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":56,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100587831","effects-of-erector-spinae-plane-block-on-opioid-consumption-anesthetic-consumption-and-hemodynamics-in-lumbar-disc-herniation-surgeries-100587831","NCT06933498","Effects of Erector Spinae Plane Block on Opioid Consumption, Anesthetic Consumption and Hemodynamics in Lumbar Disc Herniation Surgeries.","Comparison of the Effects of Preoperative and Intraoperative Erector Spinae Plane Block on Opioid Consumption, Anesthetic Consumption and Hemodynamics in Lumbar Disc Herniation Surgeries.","Inclusion Criteria:\n\n* Those over 18 and under 75 years of age,\n* Those with an American Society of Anesthesiologists (ASA) score of I-II-III,\n* Those with a body mass index (BMI) between 18-40 kg\u002Fm2\n* Patients undergoing surgery with general anesthesia\n* Patients undergoing LDH surgery (levels 1, 2, and 3)\n* Patients with informed consent\n\nExclusion Criteria:\n\n* Patients with severe cardiovascular system disease,\n* Patients with coagulation disorders,\n* Those allergic to the anesthetic and analgesic drugs to be administered,\n* Patients with infection at the injection site,\n* Patients with severe renal failure, gastrointestinal ulceration or severe asthma that prevents standard analgesia protocol\n* Patients who have previously undergone LDH surgery at the same level,\n* Patients who are planned to have surgery at more than 3 levels\n* Patients with ASA 4 and above,\n* Patients who are planned with total intravenous anasthesia(TIVA)","75 Years",{"count":21,"type":22},[25],"Lumbar disc herniation (LDH) is an increasingly common spine disorder . In patients treated surgically, inhalation anesthesia and the use of opioids for analgesic purposes are generally the chosen anesthetic methods. Surgical techniques such as discectomy, microdiscectomy, and stabilization (REF) are used to treat LDH. Although discectomy is considered the primary option in the treatment of LDH, less invasive techniques such as microdiscectomy have been applied in recent years . However, despite the use of less invasive techniques, patients experience pain after surgery . Clinicians want to avoid complications such as thromboembolism and hemodynamic deterioration that may occur due to postoperative pain, and to apply effective pain treatment for patient comfort and rapid discharge from the hospital. It has also been stated that inadequate postoperative pain treatment may increase the risk of developing chronic pain. Therefore, the use of opioids for analgesic purposes in the intraoperative and postoperative periods is quite common. However, opioid use may cause side effects that negatively affect postoperative recovery and may delay discharge. Some of these situations include delayed recovery from anesthesia, failure to perform early postoperative neurological examination due to delayed recovery, postoperative nausea and vomiting (PONV), pruritus, urinary retention, respiratory depression, gastrointestinal dysfunction, and addiction.\n\nAnother important issue is the difficulty of applying effective treatment to patients, the side effects that develop due to the applied treatments, and the increase in healthcare costs, which are important problems. Therefore, it is also very important to take a cost-effective approach while trying to treat patients at the highest level. The applied anesthesia and analgesia methods can also significantly affect the cost of surgical treatments. In particular, inhalation anesthetics used in patients receiving general anesthesia and opioids used for intraoperative and postoperative analgesia constitute a significant portion of the anesthesia cost. Therefore, strategies that will provide cost savings by reducing the use of both inhalation anesthetics and opioids are emphasized. In this context, nerve blocks or fascial plane blocks applied with local anesthetics come to the fore. With the widespread use of ultrasonography in regional anesthesia practice, regional plane blocks have also become widespread in parallel with this development and have begun to take more place in the literature. Erector spinae plane block (ESPB) is also among these blocks that are increasingly gaining ground in the literature. ESPB is a technique defined for both acute and chronic pain. ESPB is performed by administering local anesthetic (LA) to the fascial plane between the transverse process of the vertebra and the overlying erector spinae muscle. When literature data are examined, ESPB can be applied from the thoracic or lumbar levels in LDH surgery, before and after preoperative anesthesia induction, intraoperatively, at the end of surgery, before extubation or in the postoperative period. ESPB can be applied with the patient in the prone position, sitting or lateral decubitus position.\n\nIn studies conducted on patients undergoing laparoscopic cholecystectomy, it was found that ESPB reduced the amount of intraoperative inhalation anesthetic and opioid consumption. In another study examining the effect of ESPB on lumbar spine surgeries, it was found that ESPB reduced the use of intraoperative fentanyl and isoflurane and significantly shortened the recovery time. In addition, ESPB is thought to provide more effective analgesia in postoperative pain management and reduce opioid consumption and opioid-related side effects after lumbar spine surgeries. According to the results of published studies, it has been stated that ESPB is more effective for postoperative analgesia in patients undergoing lumbar surgery, significantly reduces pain scores at rest (static) and during activity (dynamic), provides a significant decrease in 24-hour opioid consumption, prolongs the first analgesic requirement period and is associated with fewer side effects.\n\nAnother important issue is to keep intraoperative hemodynamics stable within normal limits in patients under general anesthesia. Hemodynamic stability is very important to ensure that the amount of bleeding from the surgical site is kept at a minimum level, especially during LDH surgeries. It has been stated that the combined application of regional anesthesia and general anesthesia in spinal surgery provides better pain control as well as better hemodynamic stability.\n\nThis study aimed to compare the effects of preoperative and intraoperative ESPB on opioid consumption, anesthetic drug consumption, and hemodynamics in LDH surgeries.",[30,59,60],"Opioid Consumption","Postoperative Pain",[62,63,64,65,66],"Lumbar disc herniation surgery.","Erector spinae plane block","Anesthetic drug consumption","Opioid consumption","Perioperative hemodynamics","RECRUITING","2025-09-17",{"date":70,"type":38},"2025-09-18",{"date":72,"type":38},"2025-04-15",{"date":74,"type":22},"2026-01-30",{"name":76,"class":45},"Ankara Ataturk Sanatorium Training and Research Hospital",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":23,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":46},"100581978","perioperative-analgesia-with-erector-spinae-plane-block-in-liver-transplant-recipients-100581978","NCT06857331","Perioperative Analgesia With Erector Spinae Plane Block in Liver Transplant Recipients","Optimization of Perioperative Analgesia With Erector Spinae Plane Block During Major Abdominal Surgeries in Patients With Impaired Liver Function","Inclusion Criteria:\n\n* impaired liver function - cirrhosis or chronic liver disease with the development of hypocoagulation (APTT \\> 35 sec, INR \\> 1.5), thrombocytopenia, patients requiring major abdominal surgery, age \\> 18 years, written consent to participate in the study was obtained\n\nExclusion Criteria:\n\n* Platelet count \\\u003C50x109, failed ESP catheterization unilateral or bilateral, failed epidural anesthesia attempt, history of allergy or hypersensitivity to local anesthetics, hepatopulmonary syndrome, patients on mechanical ventilation before surgery, patients on CRRT before surgery, refusal to participate in the study",{"count":85,"type":22},50,[25],"The goal of this clinical trial is to learn if ESP block is safe and effective for perioperative analgesia in patients undergoing liver transplant. The main question it aims to answer are Is ESP block safe and has a minimum side effects, like hematoma? Is it effective for perioperative analgesia? Researchers will compare the results to a group of patients who underwent liver transplants without any regional anaesthesia techniques.\n\nParticipants will receive bilateral thoracic ESP block on the day of the transplantation with a subsequent bilateral catheterization.",[89,30],"Liver Transplant","2025-02-26",{"date":92,"type":38},"2025-03-04",{"date":94,"type":38},"2024-05-05",{"date":96,"type":22},"2025-12-10",{"name":98,"class":99},"Bogomolets National Medical University","OTHER",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":107,"sex":17,"minAge":18,"maxAge":54,"enrollmentInfo":108,"targetDuration":4,"studyType":110,"phases":4,"briefSummary":111,"conditions":112,"keywords":114,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":4},"100575325","effect-of-left-erector-spinae-plane-block-on-left-ventricular-functions-100575325","NCT06770816","Effect of Left Erector Spinae Plane Block on Left Ventricular Functions","ESP-LV ECHO","Inclusion Criteria:\n\nPatients undergoing elective left-sided thoracic surgery ASA I-III 18-75 years of age\n\nExclusion Criteria:\n\n1. Refusal at enrollment\n2. Request for withdrawal from the study\n3. Inability to give informed consent\n4. Emergency surgery\n5. Bleeding diathesis\n6. Presence of contraindications to the LA agents used in this study\n7. Use of chronic opioids\n8. Psychiatric disorders\n9. Presence of infection at the injection site",true,{"count":109,"type":22},23,"OBSERVATIONAL","Many studies have shown a decrease in inotropic status (intrinsic function) after blockade of cardiac sympathetic innervation with thoracic epidural anesthesia (TEA) (4,5). There is no study in the literature investigating the cardiac effects of left thoracic ESP block. We think that left thoracic ESP block, like TEA, may also have cardiac effects. Therefore, we aimed to investigate the effect of left thoracic ESP block on left ventricular functions with transthoracic echocardiography (TTE).",[30,113],"Echocardiography",[115,116,117],"erector spina plan block","left ventricle","echocardiography","2025-01-07",{"date":120,"type":38},"2025-01-13",{"date":122,"type":22},"2025-01-10",{"date":124,"type":22},"2026-02-02",{"name":126,"class":99},"Aydin Adnan Menderes University"]