[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ethics\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ethics":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,56,82,105,129,156],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":40,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100638424","ecardiacrehab---a-hybrid-patient-centered-ehealth-programme-100638424",false,"NCT07590635","eCardiacRehab - a Hybrid Patient-Centered eHealth Programme","eCardiacRehab - a Randomized Controlled Trial on a Hybrid Home-Based Patient-Centered eHealth Programme With Tailored Solutions","eCardiacRehab","Inclusion Criteria:\n\n* Adult Norwegian (or Scandinavian) speaking patients (≥ 18 years) who have a Norwegian national identification number\n* With coronary artery disease after percutaneous coronary intervention\n* Living at home\n* Have internet available\n* Provide signed informed consent\n\nExclusion Criteria:\n\n* Patients with cognitive impairment that may interfere with the ability to comply with the study protocol\n* Severe aortic stenosis\n* Severe arrhythmias\n* Expected lifetime less than one year as determined by study personnel\n* Otherwise clinically unstable\n* Not fully revascularized\n* Awaits percutaneous coronary intervention or coronary artery bypass graft surgery\n* Inability to comply with the study protocol due to any physical disability, somatic disease, or mental problems as determined by study personnel","ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","INTERVENTIONAL",[24],"NA","The overall aim of eCardiacRehab trial is to meet rehabilitation needs of patients with coronary artery disease (CAD) regardless of their access to traditional place-based rehabilitation by developing and evaluating the efficacy and cost effectiveness of an interdisciplinary and comprehensive home-based hybrid programme. eCardiacRehab address patient- and system level challenges to increase access to cardiac rehabilitation (CR). We give particular attention to older patients, women, and those with comorbidities or mental health challenges. The vision of the hybrid home-based eCardiacRehab programme is to make CR available to all.\n\neCardiacRehab is a prospective, multicentre randomized open-label blinded end point evaluation (PROBE) trial. The primary endpoint is a hierarchical composite endpoint using a win-ratio framework combining cardiovascular (CV) death, unplanned contacts to the Emergency Department (ED) for observation or admission (\\>24 hours) for CV disease, and quality of life. Inclusion criteria are adult Scandinavian speaking patients (≥ 18 years) who have a Norwegian national identification number, with CAD treated with Percutaneous Coronary Intervention (PCI), are living at home, and have internet available to them and providing signed informed consent. Exclusion criteria are patients with severe aortic stenosis, severe arrhythmias, expected lifetime less than one year as determined by study personnel, otherwise clinically unstable, not fully revascularized, awaits PCI or coronary artery bypass graft operation (CABG) or inability to comply with the study protocol due to any physical disability, somatic disease, cognitive impairment or mental health challenges as determined by study personnel.",[27,28,29,30,31,32,33,34,35,36,37,38,39],"Comorbidities and Coexisting Conditions","Ethics","Continuity of Patient Care","Older Adults (65 Years and Older)","Cost-Benefit Analysis","Adherence, Medication","Secondary Prevention of Coronary Heart Disease","Health Literacy","eHealth Literacy","Mental Health","Cardiac Rehabilitation","Womens's Health","Coronary Artery Disease (CAD)",[37,41,42],"Coronary Artery Disease","Percutaneous Coronary Intervention","RECRUITING","2026-06-18",{"date":46,"type":47},"2026-06-23","ACTUAL",{"date":49,"type":47},"2026-05-21",{"date":51,"type":21},"2037-12-31",{"name":53,"class":54},"Haukeland University Hospital","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":22,"phases":66,"briefSummary":67,"conditions":68,"keywords":4,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":78,"leadSponsor":80,"locationsCount":55},"100631545","the-impact-of-technology-supported-interactive-teaching-in-ethics-education-100631545","NCT07502079","The Impact of Technology-supported Interactive Teaching in Ethics Education","The Impact of Technology-supported Interactive Teaching in Ethics Education on Nursing Students' Ethical Sensitivity and Ethical Decision-making Levels. A Randomized Controlled Trial","Inclusion Criteria:\n\nBeing 18 years of age or older Being a second-year nursing student Using a smartphone Not having received prior nursing ethics training Voluntary participation in the research.\n\nExclusion Criteria:\n\nBeing a first, third, or fourth-year nursing student. Having received prior training in nursing ethics. Not using a smartphone.",true,{"count":65,"type":21},142,[24],"The aim of the study is to determine the effect of technology-supported interactive teaching in ethics education on nursing students' ethical sensitivity and ethical decision-making levels.",[28,69,70,71,72],"Ethical Dilemma","Nursing","Nursing Student","Professional Ethics","NOT_YET_RECRUITING","2026-05-13",{"date":76,"type":47},"2026-05-14",{"date":76,"type":21},{"date":79,"type":21},"2026-06-30",{"name":81,"class":54},"Istanbul Aydın University",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":63,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":55},"100635037","the-effect-of-aging-simulation-suits-on-nursing-students-attitudes-toward-older-adults-and-their-levels-of-compassion-100635037","NCT07547475","The Effect of Aging Simulation Suits on Nursing Students' Attitudes Toward Older Adults and Their Levels of Compassion","\"The Effect of an Aging Simulation Suit on Nursing Students' Attitudes Toward Older Adults and Their Levels of Compassion Competence: A Randomized Controlled Pretest-Posttest Study\"","Inclusion Criteria:\n\n* Being a third-year nursing student\n* Being enrolled in the HMSR 312 Geriatric Nursing course\n* Volunteering to participate in the study\n\nExclusion Criteria:\n\n* Having a physical condition that would prevent the use of an aging simulation suit\n* Having advanced orthopedic, neurological, or balance problems",{"count":90,"type":21},102,[24],"With the increasing elderly population, nursing students' attitudes toward older adults and their levels of compassion competence have become increasingly important. While traditional educational methods may be insufficient in developing these skills, experiential learning approaches offer more effective outcomes. In particular, aging simulation applications enable students to understand the physical and emotional challenges experienced by older individuals, thereby enhancing their levels of empathy and compassion. The literature reports that simulation-based education has positive effects on attitudes and awareness. Therefore, the integration of aging simulation suits into nursing education is of great importance.",[28,94,95],"Aging","Compassion","2026-04-16",{"date":98,"type":47},"2026-04-23",{"date":100,"type":21},"2026-04-25",{"date":102,"type":21},"2026-06-25",{"name":104,"class":54},"Eastern Mediterranean University",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":22,"phases":114,"briefSummary":115,"conditions":116,"keywords":4,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":55},"100466041","comparing-direct-vs-indirect-methods-for-cascade-screening-100466041","NCT05348564","Comparing Direct vs Indirect Methods for Cascade Screening","Comparing Direct and Indirect Methods for Cascade Screening in Familial Hypercholesterolemia (FH) and Long QT Syndrome (LQTS)","Proband Inclusion Criteria:\n\n* KCNQ1 Thr224Met or APOB R3527Q carrier\n* 18 years or older\n\nProband Exclusion Criteria:\n\n* None\n\nFamily Inclusion Criteria:\n\n* 1st degree relative of a KCNQ1 Thr224Met or APOB Arg3527Gln carrier\n\nFamily Exclusion Criteria:\n\n* None",{"count":113,"type":21},200,[24],"An important aspect of successful genomic medicine implementation is developing effective approaches for screening at-risk family members after probands are identified, also known as cascade screening. Most cascade screening studies conducted to date have been conducted outside the US, and very few studies have used a rigorous approach involving a comparator group or randomized controlled design. A major question in the field is how to most effectively implement cascade screening, given commonly cited communication barriers, while respecting privacy among probands and family members. This study will conduct a randomized controlled trial to assess direct contact of relatives by study team members vs indirect, or proband-initiated, contact. We will assess efficacy of the cascade screening intervention, patient-centered outcomes regarding mental, physical, and psychosocial outcomes in probands and family members, and implementation evaluation outcomes.\n\nIndividuals who are known to carry the KCNQ1 Met224Thr or APOB Arg3527Gln variant will be eligible to participate. After providing consent and being deemed eligible, individuals will be randomized in a 1:1 manner into the direct or indirect contact of family members arm of the study. The randomization will be stratified by variant to ensure equal representation of each variant in the study arms. Individuals in the indirect arm will be instructed to contact their first-degree family members about the opportunity to be screened. They will be provided with a disease-specific pamphlet and a family letter explaining the cascade screening. In the direct arm, probands will be advised that the study staff will be contacting their family members. They will be instructed to also contact their family members prior to the study team contacting them. Approximately two weeks after this meeting with the proband, the study staff will mail letters to eligible first-degree family members of the probands. If we do not hear back from individual family members, we will follow-up with another letter, telephone call, or home visit. The information contained in the letters will be the same information for both the direct and indirect arms of the study. All interested family members will receive pre-test counseling and free, in-home, saliva-based genetic testing, and post-test counseling.",[117,118,28,119],"Long QT Syndrome","Familial Hypercholesterolemia","Genetic Testing","2026-04-10",{"date":122,"type":47},"2026-04-14",{"date":124,"type":47},"2023-05-15",{"date":126,"type":21},"2027-10",{"name":128,"class":54},"University of Maryland, Baltimore",{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":137,"targetDuration":4,"studyType":139,"phases":4,"briefSummary":140,"conditions":141,"keywords":144,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100623806","life-sustaining-treatments-in-critically-ill-children-100623806","NCT07401420","Life Sustaining Treatments in Critically Ill Children","Project Plan Physicians' Experiences of the Decision-making Process Regarding Decisions to Withhold\u002FDiscontinue Life-sustaining Treatment in Children Cared for in Intensive Care Units in Sweden. A Qualitative Study.","LST-Ped-Int","Inclusion Criteria:\n\n* Specialist physicians in critical care with experience from end of life care in critically ill children.\n\nExclusion Criteria:\n\nNone\n\n\\-",{"count":138,"type":21},30,"OBSERVATIONAL","Summary of the Research on Withdrawing and Withholding Life-Sustaining Treatment for Critically Ill Children Background Medical treatments require regular evaluation to ensure they align with the patient's best interests, particularly in intensive care where quality of life is often compromised. In the context of critically ill children, the challenge increases as patients may not be fully conscious or capable of expressing their needs and preferences. While intensive care can extend life, end-of-life situations necessitate careful consideration to avoid providing futile treatments that do not benefit the patient.\n\nDecision-Making Complexity Identifying when further treatment is beneficial poses significant challenges, influenced by various factors including the wishes of the patient and guardians. Previous studies indicate variability among healthcare providers in treatment decisions, often stemming from personal experiences and emotional responses. However, comparable research focusing on critically ill children in Nordic contexts remains scarce. Medical decisions often require balancing potential benefits against the risks of extended suffering or loss of valuable time at the end of life.\n\nA previous survey on end-of-life care in Europe indicated similar attitudes across regions but highlighted the need for cultural considerations. Sweden's distinct social and cultural values, characterized by individualism and secularism, may influence practices surrounding life-sustaining treatment.\n\nResearch Aims This research aims to investigate the factors affecting decision-making regarding the withdrawal and withholding of life-sustaining treatments for critically ill children in Swedish and Nordic intensive care units (ICUs). It will examine practitioners' experiences, attitudes, and the relative impact of children's autonomy in these decisions, excluding neonatal care.\n\nKey scientific questions focus on Physicians' attitudes and challenges regarding treatment withdrawal.\n\nMethodology\n\nSemi-structured interviews in multiple ICUs to explore ethical dilemmas faced by physicians.",[142,28,143],"Critical Illness","End of Life Care",[145,28,146],"Critical illness","End of life care","2026-02-06",{"date":149,"type":47},"2026-02-10",{"date":151,"type":21},"2026-02-01",{"date":153,"type":21},"2027-12-31",{"name":155,"class":54},"Göteborg University",{"id":157,"slug":158,"hasResults":11,"nctId":159,"briefTitle":160,"officialTitle":161,"acronym":4,"eligibilityCriteria":162,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":22,"phases":166,"briefSummary":167,"conditions":168,"keywords":170,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":4},"100611027","the-effect-of-digital-games-on-ethical-sensitivity-and-decision-making-in-nursing-students-100611027","NCT07235241","The Effect of Digital Games on Ethical Sensitivity and Decision Making in Nursing Students","The Effect of Digital Game-Based Teaching Methods on the Development of Ethical Sensitivity and Ethical Decision-Making Processes in Nursing Students","Inclusion Criteria:\n\nStudents must:\n\n* Have taken and successfully completed the Nursing Ethics course,\n* Be a fourth-year nursing student who has successfully completed all professional courses and is undertaking the 'Professional Training in the Workplace' placement.\n\nExclusion Criteria:\n\n* Students who have not taken the Nursing Ethics course or have failed the course before taking the Professional Training in the Workplace course.\n* Having a conditional grade point average (CGPA \\\u003C2.00) up to the period when the data was collected.","40 Years",{"count":165,"type":21},60,[24],"The study was planned using a randomised controlled experimental design to determine the effectiveness of digital game-based teaching in the development of ethical sensitivity and ethical decision-making processes among nursing students.",[169,28],"Decision Making",[28,169,171,172],"Digital Game","Nursing Students","2025-11-17",{"date":175,"type":47},"2025-11-19",{"date":177,"type":21},"2026-03",{"date":179,"type":21},"2026-06",{"name":181,"class":54},"Istanbul Medeniyet University"]