[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"etomidate\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:etomidate":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100597754","etomidate-and-esketamine-on-postoperative-pain-after-tonsillectomy-undergoing-children-100597754",false,"NCT07062601","Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children","Effect of Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children With General Anesthesia","Inclusion Criteria:\n\n* Children who underwent elective tonsillectomy\n* Aged 2-10 years old\n* ASA class I-II\n\nExclusion Criteria:\n\n* Children with hepatic or renal dysfunction\n* Those with increased intracranial or intra-ocular pressure\n* Children with schizophrenia, bipolar disorder, and any other psychiatric condition\n* Children with preexisting chronic pain\n* Children with preoperative combined sinus bradycardia or atrioventricular block","ALL","2 Years","10 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","Objective: To explore the effect of etomidate and esketamine on postoperative pain after tonsillectomy in children.\n\nMethods: Investigators enrolled 64 children with American Society of Anesthesiologists (ASA) physical status I and II, aged 2-10 years, and scheduled for elective undergoing tonsillectomy with general anesthesia. All the enrolled patients were randomly divided into etomidate and fentanyl group (Group A) and etomidate and esketamine group (Group B). In the etomidate-fentanyl group (group A), 0.3 mg\u002Fkg etomidate and 4 µg\u002Fkg fentanyl were given at the induction of anesthesia, followed by continuous infusion of propofol at 4-12 mg\u002Fkg\u002Fh and remifentanil at 3-6 µg\u002Fkg\u002Fh until the end of the surgery, respectively; in the etomidate-esketamine group (group B), induction of anesthesia with 0.3 mg\u002Fkg etomidate and 0.5 mg\u002Fkg esketamine , followed by continuous infusion of propofol at 4-12 mg\u002Fkg\u002Fh and remifentanil at 3-6 µg\u002Fkg\u002Fh until the end of the operation. Anesthesiologists who were unaware of the grouping recorded the FlACC Pain Scale at 2 h, 8 h, and 24 h after surgery.",[27,28,29,30],"Etomidate","Esketamine","Tonsillectomy","Children",[27,32,29],"Esketomine","NOT_YET_RECRUITING","2025-07-10",{"date":36,"type":37},"2025-07-14","ACTUAL",{"date":34,"type":21},{"date":40,"type":21},"2025-11-15",{"name":42,"class":43},"Anqing Municipal Hospital","OTHER"]