[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"eus-guided-biopsy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:eus-guided-biopsy":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100611456","comparison-of-fnb-to-eus-cnb-for-pancreatic-lesions-100611456",false,"NCT07240818","Comparison of FNB to EUS-CNB for Pancreatic Lesions","Tissue Sample Comparison Between 22G FNB Needle and a New EUS Core Needle Biopsy Device for Pancreatic Lesions: A Single Center Prospective Randomized Pilot Trial","Inclusion Criteria:\n\n1. Patients who require EUS and tissue sampling of pancreatic solid lesions (size\\> 2.5 cm)\n2. Patients who can give consent\n\nExclusion Criteria:\n\n1. patients without pancreatic lesions\n2. Pregnant females\n3. Hematologic and Coagulation disorders (platelets \\\u003C 50,000\u002Fmm3, INR \\> 2, ANC \\\u003C1000)\n4. Patients with acute pancreatitis in the immediate 2 weeks before the procedure (if the lesion to be biopsied is in the pancreas)\n5. Cardiorespiratory dysfunction that precludes sedation\n6. patients unable to provide informed consent\n7. Previous chemotherapy or radiotherapy for a pancreatic neoplasm\n8. Patients who are not candidates for emergency surgery in case complications arise from the biopsy","ALL","18 Years","89 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","The primary aim of this study is to compare the tissue specimen quality and diagnostic accuracy of biopsies obtained with one puncture of a regular 22 FNB G needle and the motorized EUS CNB device of pancreatic lesions. The secondary aims are to compare the rate of blood contamination in the specimens obtained from biopsies of pancreatic lesions and the overall procedure duration. The hypothesis of this study is that the proportion of cases in which a single puncture of the lesion in question delivers adequate diagnostic tissue is higher with the motorized EUS CNB than with the 22 G FNB.",[27,28,29],"Diagnosis of a Pancreaticobiliary Disorder","Biopsy","EUS Guided Biopsy",[31,32,33,34],"FNB","EUS-CNB","Endodrill","EUS guided biopsy","NOT_YET_RECRUITING","2026-06-02",{"date":38,"type":39},"2026-06-04","ACTUAL",{"date":41,"type":21},"2026-07-01",{"date":43,"type":21},"2026-11-01",{"name":45,"class":46},"University of California, Davis","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":4},"100625578","comparison-between-triphasic-ct-abdomen-and-eus-fnb-in-characterization-of-pancreatic-lesion-100625578","NCT07424456","Comparison Between Triphasic CT Abdomen and EUS-FNB in Characterization of Pancreatic Lesion","Inclusion Criteria:\n\n* \\*Adult patients (age\\>18 years) presenting with focal pancreatic lesions detected on initial imaging.\n\n  * Patients referred for further evaluation by triphasic CT and\u002For EUS-guided biopsy.\n  * Patients able to provide informed consent\n\nExclusion Criteria:\n\n* Previous pancreatic surgery.\n\n  * Known metastatic disease at presentation.\n  * Contraindications to contrast-enhanced CT (e.g. severe renal impairment, contrast allergy)\n  * Contraindications to EUS or biopsy (e.g., coagulopathy uncorrected, severe cardiopulmonary instability).\n  * Pregnancy.",{"count":55,"type":21},50,"OBSERVATIONAL","evaluate the relationship between triphasic CT and EUS findings and the characterization of pancreatic lesions.",[29,59,60],"CT Scan","Pancreatic Lesions Located at the Body or the Tail",[62,63],"Triphasic Ct abdomen vs EUS-FNB","EUS-FNB","2026-02-13",{"date":66,"type":39},"2026-02-20",{"date":68,"type":21},"2026-02-01",{"date":70,"type":21},"2027-04-01",{"name":72,"class":46},"Assiut University",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":47},"100605925","eus-guided-fnb-induced-pancreatitis-assessment-100605925","NCT07168863","EUS-guided FNB-induced PANCREatitis Assessment","Incidence and Risk Factors of Acute Pancreatitis Following EUS-Guided Fine Needle Biopsy (EUS-FNB)","EUS-PANCREA","Inclusion Criteria:\n\nInpatients and outpatients aged 18 years or older undergoing EUS-guided FNB from a solid or cystic lesion in one of the following locations:\n\n* Pancreas\n* Ampulla of Vater\n* Distal CBD, defined as the intrapancreatic portion of the CBD where the FNB needle passes through the pancreas during biopsy\n\nExclusion Criteria:\n\n* Patients who undergo concurrent ERCP in the same day\n* Patients experiencing an ongoing episode of acute pancreatitis during EUS-FNB\n* Patients undergoing EUS-guided FNA\n* Uncorrectable coagulopathy (INR \\> 1.5)\n* Uncorrectable thrombocytopenia (platelet \\\u003C 50,000)\n* Decline to participate in the study and sign the informed consent form\n* Patients undergoing EUS-guided FNB from the proximal CBD where the FNB needle does not traverse the pancreas",{"count":82,"type":21},300,"This is a descriptive analytical study to investigate the prevalence and risk factors for pancreatitis after Endoscopic Ultrasonography-guided Fine Needle Biopsy (EUS-FNB) in patients at Shariati Hospital in Tehran. The study aims to identify risk factors for post-FNB pancreatitis to improve clinical protocols, reduce complications and treatment costs, and increase diagnostic accuracy for pancreatic and biliary tract diseases. The study will collect demographic and clinical data from all eligible patients undergoing EUS-guided FNB during the study period. Amylase and lipase levels will be measured in all enrolled patients 24 hours post-procedure. Pancreatitis will be diagnosed based on abdominal pain and amylase or lipase levels exceeding three times the normal range 24 hours after the procedure. The outcomes will be independently adjudicated by an expert gastroenterologist not involved in the EUS procedures by reviewing participants' medical records. The consensus definition will be applied as a diagnostic framework (rather than a strict definition) so that the adjudicator can use their best judgment in cases that does not strictly satisfy the criteria. The patients will be contacted 24-72 h after the procedure to follow-up on any potential complications. The study plans to enroll at least 300 patients.",[85,29],"Pancreatitis, Acute",[87,88],"acute pancreatitis","EUS-guided FNB","RECRUITING","2025-09-12",{"date":92,"type":39},"2025-09-15",{"date":94,"type":39},"2025-09-11",{"date":96,"type":21},"2027-03-12",{"name":98,"class":46},"University of Tehran"]