[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"executive-function-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:executive-function-disorder":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100562502","goal-management-training-gmt-for-improvement-of-cognitive-control-function-after-acquired-brain-injury-100562502",false,"NCT06604000","Goal Management Training (GMT) for Improvement of Cognitive Control Function After Acquired Brain Injury","Inclusion Criteria:\n\n* Patients aged 18-65 with acquired brain injury with no concomitant diseases minimum 12 months' post-injury\u002Fsurgery, reporting cognitive control problems by structured interview or clinical performance measures.\n\nExclusion Criteria:\n\n* Non-fluency in Norwegian Language\n* Major psychiatric disorder or reported ongoing alcohol or substance abuse.\n* Premorbid neurological disease or insult and\u002For comorbid neurological disease.\n* Aphasia or other specified language problems causing potential communication problems.\n* Impaired basic linguistic, mnemonic, motor, or perceptual function that can interfere with the ability to engage with training or estimated IQ \\\u003C 85","ALL","18 Years","65 Years",{"count":19,"type":20},116,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to investigate predictors of treatment outcome, and the effect of individual treatment components of Goal Management Training (GMT) for improvement of cognitive control function in people with acquired brain injury (ABI).\n\nPrimary aim: To identify demographic, clinical and cognitive predictors of treatment response in Goal Management Training after acquired brain injury (ABI)?\n\nSecondary aims: To investigate the effects of a) extended cuing (via a smartphone) and b) a booster module?\n\n* All included participants will receive Goal Management Training in groups of 4-6 patients, as implemented in a rehabilitation hospital setting (St. Olavs Hospital, Trondheim University Hospital). The standard treatment (\"GMT Usual\") consists of 10 sessions, delivered as 2 sessions a day, one day per week, over 5 weeks.\n* All participants will be asked to complete self-report measures and performance-based cognitive testing at baseline (T1), immediately after the main treatment period (T2), at 6 months (T3), and 1 year (T4) after treatment.\n* After baseline assessment, 50% of participants will be randomized to receive extended cuing through a smartphone application (\"GMT Cuing\") - intended to facilitate the effect of between-session tasks (homework) completed by the participants. These participants will, in addition to the standard treatment, on a daily basis receive a message that says \"STOP\" as a reminder to do their home assignments.\n* After completion of the 10 GMT sessions and the first post-treatment assessment immediately after the main treatment period, 50% of the participants will be randomized to receive an additional booster module (\"GMT Boost\") 3 months after the last ordinary GMT module - intended to facilitate a prolonged treatment response. The remaining 50% will receive no booster module (\"GMT No Boost\")\n* Randomization will be carried out on treatment group-level (all patients in the same group receive the same treatment). The total anticipated sample size is N = 116 patients.\n* The Global Executive Composite (GEC) score derived from BRIEF-A will be used as the primary outcome measure. A selection of other included measures will be used as secondary outcome measures.",[26,27],"Acquired Brain Injury","Executive Function Disorder",[29,30,31,32,33,34],"acquired brain injury","goal management training","executive function","cognitive control","GMT","cognitive rehabilitation","RECRUITING","2025-12-01",{"date":38,"type":39},"2025-12-02","ACTUAL",{"date":41,"type":39},"2023-09-26",{"date":43,"type":20},"2030-01-01",{"name":45,"class":46},"St. Olavs Hospital","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":15,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":79},"100544502","neurofeedback-based-digital-therapeutics-for-the-diagnosis-and-treatment-of-adhd-in-children-100544502","NCT06369714","Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children.","Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Children.","ADHD","Inclusion Criteria:\n\n* Meet the diagnostic criteria established by the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) for ADHD.\n* Digital Cancellation Test total score\\\u003C50 points.\n* Raven's Standard Progressive Matrices score≥85.\n* 6 years ≤ Age\\\u003C12 years.\n* No interventions for ADHD received within 4 weeks.\n* No color blindness.\n\nExclusion Criteria:\n\n* Patients with organic mental disorders, schizophrenia, bipolar disorder, depressive disorders, and other psychiatric conditions.\n* Patients with comorbid autism spectrum disorder, Tourette's syndrome, and other neurodevelopmental disorders.\n* Patients with comorbid conduct disorders.\n* Patients with severe traumatic brain injury or neurological disorders.\n* Patients with a history of severe somatic diseases.\n* Patients with a history of substance or drug dependency.","6 Years","12 Years",{"count":59,"type":20},210,[23],"A multi-center, randomized controlled trial is being conducted to investigate the efficacy of a novel digital therapeutics (DTx) program that utilizes a cross-training approach between neurofeedback training and executive function training for pediatric patients (aged 6-12) diagnosed with ADHD. This gamified interactive program is designed to improve attention deficits and executive function impairments in pediatric patients with ADHD. It is delivered through an engaging iPad game in a home-based treatment format. Patients will be randomly assigned to one of three groups: medication alone, digital therapeutics alone, or a combination of both interventions. Subjects will undergo 30 treatment sessions over the 8-week period, with each session lasting 30 minutes. Investigators will reassess symptoms of ADHD, executive functions, and objective measures of attention at the end of the treatment. Additionally, questionnaires will be distributed to parents to gather their insights and feedback on the treatment approach. This innovative digital therapeutics approach is expected to improve ADHD symptoms individually and enhance therapeutic outcomes when used alongside conventional drug treatment regimens.",[63,27],"Attention Deficit Disorder With Hyperactivity",[65,66,67,68,69],"Digital Therapeutics","Neurofeedback","Attention Deficit Disorders with Hyperactivity","Children","Executive function disorder","2025-06-08",{"date":72,"type":39},"2025-06-10",{"date":74,"type":39},"2023-02-24",{"date":76,"type":20},"2025-12-31",{"name":78,"class":46},"Lei Lei, MD",2,{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":15,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":21,"phases":92,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":47},"100555348","the-purpose-of-this-research-is-to-investigate-the-effects-of-aerobic-exercise-on-executive-function-in-obese-children-100555348","NCT06510920","The Purpose of This Research is to Investigate the Effects of Aerobic Exercise on Executive Function in Obese Children","Effects of Aerobic Exercise on Executive Function Among Obese Children","Inclusion Criteria:\n\n* Age: Obese children aged 8-10 years.\n* The body weight was obese or above.\n* There was no history of other concomitant diseases related to obesity,Children with simple obesity.\n* Normal blood pressure.\n* The International Physical Activity Scale (IPAQ, Chinese version) measured participants 'physical activity in the past 7 days, with internal consistency reliability r = 0.927(Qiu NN, 2004).\n* The physical condition Safety questionnaire (PAR-Q) was used to ensure that the exercise in thistest could be completed safely(Appendix2).\n* Uncorrected or corrected visual acuity was normal.\n\nExclusion Criteria:\n\n* In the process of the experiment, it is necessary to participate in other forms of intervention experiments. If the members of the experimental group or the control group are engaged in regular exercise or planned training, they need to be excluded from the experiment.\n* If the members of the experimental group are absent from work for more than1 week, the samples will be deemed to fall off. If the members of the experimental group and the control group fail to participate in any of the data collection on time, they will be excluded.\n* Before and after the experiment, the members of the experimental group or the control group who limited their movement due to sprain and other reasons were excluded.They were randomly divided into experimental group and control group.",true,"8 Years","10 Years",{"count":91,"type":20},62,[23],"The goal of this clinical trial is to learn if aerobic exercise improves executive functioning in obese children. It will also understand the effects of aerobic exercise on executive functioning in obese children. The main questions it aims to answer are:\n\n1. What are the levels of executive functioning(inhibitory function, working memory, and cognitive flexibility) in normal-weight and obese children aged 8-10 years?\n2. What are the differences on executive function before and after aerobic exercise intervention among obese children?\n3. Do factors of health, gender and ages influence students' executive functioning (inhibitory function, working memory, and cognitive flexibility)? Researchers will compare the aerobic exercise intervention group with the no-aerobic exercise group in terms of executive function to see if and how much aerobic exercise has an effect on executive function.\n\nParticipants will:\n\n(1) The aerobic exercise intervention group was given football and volleyball exercise intervention, and the control group was given routine school life for 3 months.\n\n2\\. Record the participants before and after the intervention level of executive function.",[27,95],"Obesity, Childhood",[97,98,99,100],"Executive function","Obese Children","Aerobic Exercise","Mental health","NOT_YET_RECRUITING","2024-07-18",{"date":104,"type":39},"2024-07-19",{"date":106,"type":20},"2024-08-01",{"date":108,"type":20},"2024-12-30",{"name":110,"class":46},"Jing Xin"]