[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"executive-functioning\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:executive-functioning":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,52,84,116],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100582242","acupuncture-for-adhd-acupoint-data-mining-clinical-effectiveness-and-interviews-to-explore-treatment-outcomes-100582242",false,"NCT06860763","Acupuncture for ADHD: Acupoint Data Mining, Clinical Effectiveness, and Interviews to Explore Treatment Outcomes.","Clinical Study on Acupuncture Treatment for Attention Deficit Hyperactivity Disorder.","ACU-ADHD","Inclusion Criteria:\n\nPatients will be considered for enrolment if they meet the criteria of:\n\n* A confirmed diagnosis of ADHD based on the DSM-5 criteria for ADHD (Western medical diagnosis) and in accordance with the ADHD Chinese Medicine Clinical Trial Design and Evaluation Technical Guidelines.\n* Aged between 6 and 12 years.\n* No use of any other pharmacological treatments (both Western and traditional Chinese medicine) within the two weeks prior to the start of the study.\n* An IQ score of greater than 80, as determined by the Raven's Progressive Matrices test.\n* The participant has not participated in any other clinical trials.\n\nExclusion Criteria:\n\nPatients will be excluded from the study if they meet any of the following criteria:\n\n* Do not meet the inclusion criteria\n* Have comorbid psychiatric disorders, severe medical or psychiatric conditions that may interfere with the study (e.g., epilepsy, severe anxiety), pervasive developmental disorders, intellectual disability, or a history of suicidal or self-harming behavior\n* Have participated in any other drug clinical trials within the past 3 months.\n* Have severe comorbid conditions such as cardiovascular, hepatic, renal, or hematologic diseases.\n* Have any other conditions that the researchers believe may interfere with the assessment of treatment efficacy or safety.","ALL","6 Years","12 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to evaluate the efficacy of acupuncture as a treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6-12 years. Using a mixed-methods approach, the research will triangulate data from acupoint data mining, treatment outcomes assessment, and patient perspectives to provide a comprehensive analysis of acupuncture's potential therapeutic benefits for ADHD.\n\nThis prospective cohort study will recruit children diagnosed with ADHD, assigning them to receive either acupuncture combined with traditional Chinese herbal treatment or herbal treatment alone. Quantitative assessments using the the SNAP-IV, Conners 3-P, BRIEF-2, PedsQL™ 4.0 Generic Core Scales, PSQI and CGI that will be complemented by qualitative interviews to capture nuanced patient experiences and treatment outcomes.\n\nThe study will span 12 months, commencing on March 1st, 2025 with an expected completion by February 28th, 2026. By integrating quantitative assessments with qualitative insights, it aims to provide comprehensive evidence on acupuncture's role in ADHD management. Findings may inform clinical guidelines and enhance patient-centered care approaches.",[28,29,30,31,32,33],"Acupuncture","ADHD - Attention Deficit Disorder With Hyperactivity","Children","Interview","Executive Functioning","Quality of Life (QOL)",[28,35,36,31,37,38],"ADHD","Executive functioning","TCM","PedsQL","RECRUITING","2026-06-21",{"date":42,"type":43},"2026-06-23","ACTUAL",{"date":45,"type":43},"2024-10-15",{"date":47,"type":22},"2027-01-31",{"name":49,"class":50},"The Third Affiliated Hospital of Beijing University of Chinese Medicine","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":19,"enrollmentInfo":60,"targetDuration":4,"studyType":23,"phases":62,"briefSummary":63,"conditions":64,"keywords":68,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":4},"100614574","pilot-trial-of-an-emotion-regulation-and-executive-functioning-intervention-for-self-injurious-thoughts-and-behaviors-sitbs-in-children-100614574","NCT07281365","Pilot Trial of an Emotion Regulation and Executive Functioning Intervention for Self-Injurious Thoughts and Behaviors (SITBs) in Children","Proof-of-Concept Trial of an Emotion Regulation and Executive Functioning Intervention for SITBs in Children","Inclusion Criteria:\n\n* between the ages of 7-12\n* at least one caregiver\u002Flegal guardian able to participate (more permitted)\n* experienced at least one episode of SITBs within the last month\n* ability to attend weekly sessions in-person or via telehealth\n* ability to attend baseline and 12-week assessments in-person.\n* estimated verbal IQ of 70 or greater\n\nExclusion Criteria\n\n* symptoms interfering with ability to participate in assessments\u002Ftherapy (i.e., psychosis)\n* estimated verbal IQ\\\u003C70 or previous diagnosis of intellectual development disorder\n* requiring inpatient psychiatric stabilization or high-intensity intervention to prevent hospitalization\n* active substance use\n* ward of the state","7 Years",{"count":61,"type":22},52,[25],"The goal of this study is to develop and test an outpatient intervention for preadolescents (ages 7-12) with self-injurious thoughts and behaviors (SITBs).\n\nThe main questions it aims to answer are:\n\n1. Does the newer intervention lead to better engagement of families in treatment compared to treatment as usual (TAU)?\n2. Is the new intervention feasible, acceptable, and appropriate?\n3. Does the new intervention lead to more improvements in SITBs, mental health symptoms, and treatment targets compared to TAU?\n\nPreadolescent participants with SITBs and their families will be randomized to either the new intervention or TAU, which will consist of the typical interventions the study therapist would use for preadolescents with SITBs. Participants will:\n\n1. Complete an initial baseline assessment to determine eligibility and assess SITBs, mental health symptoms, executive functioning, and emotion regulation\n2. Participate in a \\~weekly, outpatient intervention lasting around 3-4 months\n3. Complete additional assessments at mid-treatment, post-treatment, and 3-month follow-up\n4. Participate in an interview sharing their perceptions of the intervention",[65,66,32,67],"Self-injury","Suicidal Ideation and Behavior","Emotion Regulation",[69,30,70,71,72,73],"Preadolescents","Self-Injury","Suicidal ideation and behavior","Randomized controlled trial","Feasibility","NOT_YET_RECRUITING","2026-05-13",{"date":77,"type":43},"2026-05-14",{"date":79,"type":22},"2026-12",{"date":81,"type":22},"2028-05",{"name":83,"class":50},"University of Colorado, Denver",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":90,"sex":17,"minAge":18,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":23,"phases":94,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":115},"100566123","hybrid-effectiveness-implementation-trial-of-an-executive-functioning-intervention-for-childrens-mental-health-services-100566123","NCT06651086","Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services","Inclusion Criteria:\n\nMental Health Programs:\n\n* Publicly-funded\n* Providing outpatient or school-based psychotherapy services to children\n* Have at least 8 mental health providers on staff\n\nTherapists:\n\n* Employed as staff or trainee at a participating program\n* Employed at the program for at least the next 12 months\n* Providing psychotherapy services to children\n* Has an eligible child on current caseload (see below)\n\nAutistic Child\u002FCaregiver Participants (enrolled in a dyad with a participating therapist):\n\n* Child age 6-12 years\n* Receiving services from an enrolled therapist\n* Documented or suspected\\* autism diagnosis\n\n  * In the event of suspected autism diagnosis, the presence of elevated autism symptoms on the Social Responsiveness Scale-2nd Edition or the Autism Diagnostic Observation Scale-2nd Edition\n\nNon-Autistic Child\u002FCaregiver Participants (enrolled in a dyad with a participating therapist):\n\n* Child age 6-12 years\n* Receiving services from an enrolled provider\n* No history of documented or suspected autism diagnosis",true,"99 Years",{"count":93,"type":22},672,[25],"This project aims to follow up on a prior project examining the impact of training therapists in an executive functioning intervention Unstuck and On Target (UOT) adapted for community mental health settings. Study aims are to test the clinical and implementation effectiveness of training mental health therapists in Unstuck and On Target, an executive functioning intervention, relative to Unified Protocol for Children, a transdiagnostic intervention for emotional disorders. This includes examining the implementation of Unstuck and associated outcomes (e.g., effective delivery, expanded use of Unstuck beyond autism, the feasibility of Unstuck) and impact on changes in child executive functioning and behaviors.",[97,32],"Autism Spectrum Disorder",[99,100,101,102,103,104,105],"Autism spectrum disorder","executive functioning","emotion regulation","mental health symptoms","Unified Protcol for Children","Unstuck and On Target","evidence based intervention","2026-04-15",{"date":108,"type":43},"2026-04-20",{"date":110,"type":43},"2024-12-15",{"date":112,"type":22},"2029-08-31",{"name":114,"class":50},"San Diego State University",2,{"id":117,"slug":118,"hasResults":11,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":4,"eligibilityCriteria":122,"healthyVolunteers":90,"sex":17,"minAge":123,"maxAge":124,"enrollmentInfo":125,"targetDuration":4,"studyType":23,"phases":126,"briefSummary":127,"conditions":128,"keywords":132,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":4},"100592310","investigating-the-effectiveness-of-a-2-week-novel-non-invasive-brain-stimulation-technique-on-cognitive-outcomes-in-healthy-adults-100592310","NCT06991764","Investigating the Effectiveness of a 2-week Novel Non-invasive Brain Stimulation Technique on Cognitive Outcomes in Healthy Adults","Investigating the Effectiveness of a 2-week High-frequency Transcranial Pulsed-current Stimulation on Cognitive Outcomes in Healthy Adults: A Randomised, Double Blinded, Sham-controlled Study","Inclusion Criteria:\n\n* Male and female young (21 to 30 years) and older adults (60 to 75 years)\n* Right-handed\n* Must be a native English speaker\n* No clinical diagnosis of neurodevelopmental, mood, neurological or neurodegenerative disorders\n* Adults with cardiometabolic or cardiovascular conditions may participate if their condition is controlled and stable with medication and \u002F or lifestyle interventions\n\nExclusion Criteria:\n\n* Currently on long-term medication for pain or migraines \u002F headaches\n* Adults with metallic implants in the chest or head region\n* Adults with epilepsy, or known seizure or immediate family members that have had a seizure before\n* Had a recent head injury that resulted in a temporary loss of consciousness or of memory in the last 12 months\n* Had prior head surgery\n* Prone to fainting\n* Sensitive skin or prone to skin allergies","21 Years","75 Years",{"count":21,"type":22},[25],"The goal of this randomised controlled trial is to investigate the effects of a 2-week high-frequency transcranial pulsed current stimulation (tPCS) on cognitive outcomes in older and healthy adults. The main questions it aims to answer are:\n\n1. Would a single session of anodal tPCS over the left prefrontal cortex improve working memory, task inhibition, and task switching in healthy young and older adults, compared to anodal transcranial direct current stimulation (tDCS) and sham-tPCS?\n2. Would repeated session of anodal-tPCS (2-weeks) lead to improvements in working memory, task inhibition, and task switching in healthy young and older adults, compared to tDCS and sham-tPCS?\n3. Will tPCS be better tolerated among healthy adults, compared to tDCS?\n\nResearchers will compare tPCS \u002F tDCS \u002F sham-tPCS to see if there are any differences in cognitive outcomes after 1 session and after repeated sessions, as well as to compare the tolerance of tPCS against tDCS and sham-tPCS.\n\nParticipants will be requested to:\n\n* Undergo 1 of 3 of the following conditions: tDCS \u002F tPCS \u002F sham-tPCS\n* Complete three sessions of cognitive tasks testing working memory, inhibition and task switching at baseline (pre-stimulation), after day 1 of brain stimulation and after 10 sessions of brain stimulation (post- repeated stimulation)\n* Undergo fNIRS-EEG brain measurements concurrently with the cognitive tasks",[129,130,32,131],"Transcranial Direct Current Stimulation (tDCS)","Ageing","Transcranial Electric Stimulation",[133,134,32,135,136,137,130],"Randomised Controlled Trial","Non-Invasive Brain Stimulation","Transcranial Direct Current Stimulation","Transcranial Pulsed Current Stimulation","Healthy Adults","2025-05-18",{"date":140,"type":43},"2025-05-28",{"date":142,"type":22},"2025-06-01",{"date":144,"type":22},"2027-04-30",{"name":146,"class":50},"Nanyang Technological University"]