[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"exercise-induced-bronchospasm\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:exercise-induced-bronchospasm":77},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100324531","swiss-paediatric-airway-cohort-100324531",false,"NCT03505216","Swiss Paediatric Airway Cohort","SPAC","Inclusion Criteria:\n\n* Children and adolescents aged 0-16 years\n* Resident in Switzerland\n* Seen in a paediatric pulmonary outpatient clinic due to respiratory problems\n* Parents and patients above age 14 must be able to sign an informed consent form\n\nExclusion Criteria:\n\nPrior diagnosis of cystic fibrosis, primary ciliary dyskinesia, severe heart disease, oncological disease, neuromuscular disease or severe disability","ALL","0 Years","16 Years",{"count":20,"type":21},6000,"ESTIMATED","OBSERVATIONAL","The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians in Switzerland for recurrent wheeze, cough, and exercise- or sleep-related respiratory problems. SPAC aims to answer important questions on clinical phenotypes, prognosis, diagnosis and treatment. SPAC is part of routine care, and only clinically indicated investigations are done. The comprehensive baseline assessment includes a detailed questionnaire to families, plus test results, diagnoses and treatments from hospital records. Follow-up is via monthly questionnaires the first 12 months and thereafter annual questionnaires to families, and data from follow-up visits.\n\nCurrently, 4344 patients from 10 clinics and hospitals in Switzerland (Aarau, Basel, Bern, Chur, Horgen, Lausanne, Luzern, St. Gallen, Worb, Zurich) have been enrolled.\n\nSPAC provides real-life data on children visiting the Swiss health care system for common respiratory problems. It will provide a research platform for health services research, and for nested clinical and transitional studies.\n\nPublications and plain language summaries are listed on the study website: https:\u002F\u002Fwww.spac-study.ch\u002Fpublikationen\u002F",[25,26,27,28,29,30],"Asthma","Wheezing","Cough","Exercise Induced Bronchospasm","Inspiratory Laryngeal Obstruction","Dysfunctional Breathing","RECRUITING","2026-04-16",{"date":34,"type":35},"2026-04-21","ACTUAL",{"date":37,"type":35},"2017-06-06",{"date":39,"type":21},"2030-06-01",{"name":41,"class":42},"University of Bern","OTHER",12,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100552976","prevalence-of-eilo-among-children-with-asthma-100552976","NCT06480084","Prevalence of EILO Among Children With Asthma","The Prevalence of Exercise-Induced Laryngeal Obstruction (EILO) Amongst Children With Asthma' - a Prospective Cross-sectional Study","Inclusion Criteria:\n\n* Age 12 to 18 years\n* Paediatrician diagnosed asthma confirmed with at least one of the following during the last two years: Positive ECT (post-exercise fall in FEV1 \\> 10%) \u002F Positive methacholine test (PC20 value of ≤8 mg\u002FmL) \u002F Bronchodilator reversibility (increase in FEV1 ≥12% and\u002For ≥200 mL following inhalation of 200-400 μg short-acting β2-agonists)\n\nExclusion Criteria:\n\n* Other severe cardiopulmonary disease\n* Inability to perform ECT or CLE test\n* Inability to perform technically acceptable spirometry\n* Asthma exacerbation or respiratory tract infection in the last 2 weeks\n* Short-acting β2-agonists or long-acting β2-agonists use less than respectively 8 and 24 hours before the ECT or CLE test\n* Oral corticosteroid use in the 4 weeks before the ECT or CLE test","12 Years","18 Years",{"count":54,"type":21},200,"INTERVENTIONAL",[57],"NA","The goal of this cross-sectional study is to investigate the prevalence of Exercise Induced Laryngeal Obstruction (EILO) in children with asthma.\n\nThe hypothesis is that the prevalence will be around 15%, which is higher than the prevalence of 5-8% among the general adolescent population. This is based on the increased prevalence of EILO among adult asthmatics.\n\nParticipants who are referred for an Exercise Challenge Test will perform an additional Continuous Laryngoscopy during Exercise Test with expiratory FEV1 curves, and fill in the Borg scale for dyspnea, Asthma Control Test, EILODI questionnaire and DISCO-RC questionnaire.",[60,61,62,63,64,65],"Exercise Induced Laryngeal Obstruction","Asthma in Children","Exercise-Induced Bronchospasm","Exercise-Induced Bronchoconstriction","Dyspnea","Larynx","NOT_YET_RECRUITING","2024-06-26",{"date":69,"type":35},"2024-06-28",{"date":71,"type":21},"2024-08-01",{"date":73,"type":21},"2026-04-30",{"name":75,"class":42},"Medisch Spectrum Twente",1,"Exercise-induced Bronchospasm"]