[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"extracorporeal-shock-wave-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:extracorporeal-shock-wave-therapy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,53,76,109],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100638885","extracorporeal-shock-wave-therapy-in-lower-extremity-lymphedema-100638885",false,"NCT07626645","Extracorporeal Shock Wave Therapy in Lower Extremity Lymphedema","Efficacy of Extracorporeal Shock Wave Therapy (ESWT) in Lower Extremity Lymphedema: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18 to 80 years\n* Clinical diagnosis of lower extremity lymphedema established at least 6 months prior to enrollment\n* Completion of at least one cycle of CDT Phase 1 (intensive decongestive phase) within the preceding six months\n* Currently in CDT Phase 2 (maintenance phase) with active use of compression garments\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Active chemotherapy or radiotherapy\n* Active infection\n* Lower extremity vascular diseases including deep vein thrombosis or arterial insufficiency\n* Presence of a cardiac pacemaker\n* Pregnancy\n* Bleeding disorders","ALL","18 Years","80 Years",{"count":20,"type":21},36,"ESTIMATED","INTERVENTIONAL",[24],"NA","Lower extremity lymphedema is a chronic and progressive condition associated with significant functional impairment and reduced quality of life. The current gold-standard treatment is Complex Decongestive Therapy (CDT); however, a substantial proportion of patients continue to experience persistent symptoms during the maintenance phase. This prospective, randomized, double-blind, placebo-controlled clinical trial aims to evaluate the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) as an adjunct to standard CDT maintenance therapy in patients with lower extremity lymphedema. Participants will be randomly allocated to either an active ESWT group or a sham ESWT group, with both groups continuing standard CDT maintenance throughout the study. ESWT will be administered twice weekly for five sessions. Changes in limb volume, skin thickness and subcutaneous tissue thickness assessed by ultrasonography, pain, functional status, and quality of life will be evaluated at baseline, after treatment, and at one-month follow-up.",[27,28,29,30,31],"Lymphedema, Lower Limb","Extracorporeal Shock Wave Therapy","Edema Leg","Sham-controlled","Placebo Control Design",[33,34,35,36,37,38,39],"Lower Extremity Lymphedema","Extracorporeal Shock Wave Therapy (ESWT)","Complex Decongestive Therapy (CDT)","Limb Volume","Ultrasonography","skin and subcutaneous tissue thickness","Quality of Life","NOT_YET_RECRUITING","2026-06-02",{"date":43,"type":44},"2026-06-04","ACTUAL",{"date":46,"type":21},"2026-06-22",{"date":48,"type":21},"2027-02-01",{"name":50,"class":51},"Gazi University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":16,"minAge":17,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":52},"100637975","eswt-in-the-treatment-of-plantar-fasciitis-100637975","NCT07626723","ESWT in the Treatment of Plantar Fasciitis","The Effect of ESWT Session Count on Clinical Parameters in the Treatment of Chronic Plantar Fasciitis; Randomized Controlled Study","Inclusion Criteria:\n\n* Patients aged 18-65, both male and female, diagnosed with plantar fasciitis based on anamnesis and physical examination.\n* Patients must have had symptoms for at least 3 months.\n* Patients must consent to participate in the study according to the informed consent form.\n\nExclusion Criteria:\n\n* Complaint lasting less than 3 months\n* Having received an injection in the heel area within the last 6 months\n* Having applied physical therapy modalities to the heel area within the last 6 months\n* Bilateral complaint\n* Pregnancy\n* Malignancy\n* Epilepsy\n* History of cardiac pacemaker\n* Anticoagulant use\n* History of systemic inflammatory disease\n* History of fracture or surgery in the lower extremity\n* Presence of an open wound in the heel area\n* Hypersensitivity in the patient\n* Systemic infection in the patient\n* Uncontrolled hypertension in the patient\n* Uncontrolled diabetes in the patient\n* Inability of the patient to cooperate\n* History of neuromuscular disease affecting balance parameters\n* Patient's unwillingness to participate in the study",true,"65 Years",{"count":63,"type":21},57,[24],"Extracorporeal shock wave therapy (ESWT) has become widely preferred in Turkey and worldwide in recent years for the treatment of musculoskeletal diseases due to its non-invasive nature, ease of application, and low risk of complications, as it does not require surgical intervention. However, there is no consensus in the literature regarding the energy level used in ESWT applications, the frequency of application, and especially the ideal number of sessions. Different centers apply varying protocols in clinical practice, which can lead to heterogeneity in treatment outcomes. Scientifically determining the effect of variation in the number of ESWT sessions on clinical outcomes is important for establishing standard treatment protocols. Therefore, the aim of our study is to contribute to the existing literature by investigating the effect of variation in the number of ESWT sessions on clinical parameters such as pain, functional status, and quality of life in the treatment of chronic plantar fasciitis, and to develop more effective and evidence-based treatment approaches in patient management.",[67,28,37],"Plantar Fasciitis","2026-06-01",{"date":43,"type":44},{"date":71,"type":21},"2026-07-01",{"date":73,"type":21},"2027-03-15",{"name":75,"class":51},"Kirsehir Ahi Evran Universitesi",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":83,"maxAge":18,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":93,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":52},"100553873","is-adding-extracorporeal-shock-wave-therapy-to-physiotherapy-and-corticosteroid-injection-beneficial-for-frozen-shoulder-100553873","NCT06491745","Is Adding Extracorporeal Shock Wave Therapy to Physiotherapy and Corticosteroid Injection Beneficial for Frozen Shoulder","Is Adding Extracorporeal Shock Wave Therapy to Physiotherapy and Corticosteroid Injection Beneficial for Frozen Shoulder?","Inclusion Criteria:\n\n1. age between 20 to 80 years old;\n2. shoulder pain for ≥ 1 month;\n3. \\> 30% loss of passive range of motion (ROM) of the affected shoulder in external rotation and\u002For abduction, comparing with the sound side;\n4. pain visual analog scale on maximal passive external rotation or abduction \\> 4;\n5. showing willing to receive ESWT, shoulder joint injection, and attend regular physical therapy programs for 8 weeks.\n\nExclusion Criteria:\n\n1. severe systemic disorders including cancer, stroke, or cardiopulmonary diseases;\n2. uncontrolled DM;\n3. rotator cuff tear or calcification of the affected shoulder;\n4. fracture, dislocation, or arthritis of the shoulder due to rheumatic disorders;\n5. a history of drug allergy to local anesthetics or corticosteroids;\n6. pregnancy;\n7. receiving ESWT, corticosteroid joint or bursa injection of the affected shoulder during the preceding three months","20 Years",{"count":85,"type":21},94,[24],"Frozen shoulder, or adhesive capsulitis of the shoulder, is a common clinical problem characterized by pain, loss of both passive and active range of motion (ROM) of glenohumeral joint (GHJ), leads to functional limitation, and reduces quality of life. Primary frozen shoulder occurs without any obvious connection to any other condition, and secondary frozen shoulder is related to some medical problems, such as an injury, inflammatory, immunological, and endocrine conditions, or surgery of the shoulder. The prevalence of frozen shoulder is 2%-5% in general population, usually between 40 to 60 years old, and more in female. Diabetes patients have more chance of developing frozen shoulder than general population and the prevalence was 13.4%.\n\nFrozen shoulder is clinically divided into 3 overlapping phases. The painful freezing phase has a duration of 10 to 36 weeks and is characterized by pain and stiffness around the shoulder, which may worsen at night. The frozen phase is characterized by restricted ROM with a gradual relief of pain, which occurs at 4 to 12 months. The thawing phase with spontaneous improvement in the ROM takes 12 to 42 months. .Although frozen shoulder is a self-limited condition, the recovery may be slow and incomplete.\n\nTreatment of frozen shoulder consists of physiotherapy, oral medication (nonsteroidal anti-inflammatory drugs or corticosteroid), intra-articular corticosteroid injection, hydrodilatation, suprascapular nerve block, mobilization, manipulation under anesthesia, and operative intervention (arthroscopic release or open release). Because of the uncertainty of the efficacy and risk of surgical treatment, nonsurgical treatments are more likely chosen by patients. Among them, intra-articular steroid injection and physical therapy are commonly used nonsurgical treatments and have shown some benefits. .Because the clinical picture of frozen shoulder may be similar to, or combining with chronic subacromial bursitis, especially in the freezing stage, concomitant subacromial\u002Fsubdeltoid (SASD) bursa injection may be needed for treatment of frozen shoulder. In addition, the 3 stages of frozen shoulder often overlap and the clinical symptoms of patients are complex, adjuvant therapy is often needed throughout the course of treatment. Even after physical therapy (PT) and corticosteroid injection, mild to moderate contracture, especially external rotation, abduction, and internal rotation may still be present.\n\nOver the past few years new evidence has emerged on the effectiveness of extracorporeal shock wave therapy (ESWT) in the treatment of many musculoskeletal disorders. Briefly, ESWT has been shown to promote neovasculization, amplify growth factor and protein synthesis, increase of pain inhibiting substance, alteration of pain receptor neurotransmission, and intensification of tissue regeneration. Furthermore, ESWT can produce a cavitation effect between tissues, cause intertissue release, promote the separation of adhesion, and release the adhesive tissue. Because of its analgesic, anti-fibrotic, and anti-inflammatory effect, application of ESWT as main treatment or an adjunct to other interventions has been tried. Knoblock et al found that focused ESWT can reduce pain in painful nodules in Dupuytren's disease; in a randomized controlled trial Chen et al showed focused ESWT was superior to oral corticosteroid for frozen shoulder, although oral corticosteroid is not commonly prescribed for patients with frozen shoulder. Vahdatpour compared ESWT with sham ESWT on treatment of frozen shoulder after 40mg triamcinolone intra-articular injection, and found that ESWT group seemed to have positive effects on treatment, and quicker return to daily life. Another two studies investigating application of radial shock wave to patients with frozen shoulder showed improvement of ROM, even for diabetic patients. A systemic review and meta-analysis also showed ESWT seems beneficial to patients with frozen shoulder and could be used as an adjunct therapy to routine treatments. However, the authors mentioned that the quality of the included randomized controlled trials were hampered by significant heterogeneity regarding long-term analgesia and joint ROM.\n\nBecause the effect of ESWT against frozen shoulder has not been well established, we aim to investigate whether adding ESWT to corticosteroid injection and routine PT beneficial for patients with frozen shoulder? We hypothesize that ESWT would be a positive adjunctive therapy in the treatment of frozen shoulder.",[89,90,91,28,92],"Frozen Shoulder","Corticosteroid Injection","Physical Therapy","Rehabilitation",[94,95,96,97,98],"Frozen shoulder","corticosteroid injection","physical therapy","extracorporeal shock wave therapy","rehabilitation","RECRUITING","2025-12-22",{"date":102,"type":44},"2025-12-30",{"date":104,"type":44},"2024-08-01",{"date":106,"type":21},"2028-12-31",{"name":108,"class":51},"Shin Kong Wu Ho-Su Memorial Hospital",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":4,"eligibilityCriteria":115,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":116,"enrollmentInfo":117,"targetDuration":4,"studyType":22,"phases":119,"briefSummary":120,"conditions":121,"keywords":124,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":136,"locationsCount":52},"100549760","clinical-utility-of-eswt-in-restoring-hand-function-of-patients-with-nerve-injury-and-hypertrophic-scars-due-to-burns-100549760","NCT06438224","Clinical Utility of ESWT in Restoring Hand Function of Patients With Nerve Injury and Hypertrophic Scars Due to Burns","Clinical Utility of Extracorporeal Shock Wave Therapy in Restoring Hand Function of Patients With Nerve Injury and Hypertrophic Scars Due to Burns","Inclusion Criteria:\n\n* ≥ 18 years old\n* had sustained a deep partial-thickness (second-degree) or a full-thickness (third-degree) burn in the right dominant hand, which had been treated with a split-thickness skin graft (STSG) after the thermal injury\n* nerve injury to the hand was confirmed by electromyography\n* \\\u003C 6 months prior to the enrollment\n\nExclusion Criteria:\n\n* musculoskeletal diseases (fracture, amputation, rheumatoid arthritis, and degenerative joint diseases) of the hands\n* acute infection\n* malignant tumors\n* coagulopathy\n* pregnancy\n* potential for additional skin damage if exposed to ESWT and conventional occupational therapy.","75 Years",{"count":118,"type":21},120,[24],"Joint contractures and nerve injuries are common after hand burns. Extracorporeal shock wave therapy (ESWT) is effective not only for the regeneration of various tissues, including scar tissues, but also for reducing pain and pruritus in patients with burns. Researchers have attempted to explore the effects of ESWT on hand dysfunction caused by nerve injury following burns. The investigators planned to evaluate the effects of ESWT (compared to sham stimulation) on hands with nerve injury and hypertrophic scars and thereby on hand function. The ESWT parameters were as follows: energy flux density, 0.05-0.30 mJ\u002Fmm2; frequency, 4 Hz; 1000 to 2000 impulses per treatment; and 12 treatments, one\u002Fweek for 12 weeks. Outcome measures were as follows: 10-point visual analog scale for pain, Jebsen-Taylor hand function test, grip strength, Purdue Pegboard test, ultrasound measurement of scar thickness, and skin characteristics before and immediately after 12 weeks of treatment.",[122,28,123],"Hand Injuries","Burns",[125,126,127,128,129],"Extracorporeal shock wave therapy","hypertrophic scar","burns","hand function","nerve injury","2024-08-18",{"date":132,"type":44},"2024-08-20",{"date":134,"type":44},"2023-01-01",{"date":132,"type":21},{"name":137,"class":51},"Hangang Sacred Heart Hospital"]